Chapter 7 Body Systems
... Functional Anatomy of Cells • The typical cell (Figure 3-1) – generic cell ...
... Functional Anatomy of Cells • The typical cell (Figure 3-1) – generic cell ...
bacterial cell shape - Jacobs-Wagner Lab
... glycan strands to the existing structure, which are then automatically pulled into the stress-bearing layer by the cleavage and removal of one old strand46. The large number and variety of hydrolases have so far hindered rigorous testing of these hypotheses. Mechanical properties. As isolated peptid ...
... glycan strands to the existing structure, which are then automatically pulled into the stress-bearing layer by the cleavage and removal of one old strand46. The large number and variety of hydrolases have so far hindered rigorous testing of these hypotheses. Mechanical properties. As isolated peptid ...
Role for Rab7 in maturation of late autophagic vacuoles
... lysosomal enzyme inhibitors. The amount of the membraneassociated, 16 kDa LC3II increased at the same rate as the volume fraction of autophagic vacuoles in HeLa cells, while the amount of the soluble, 18 kDa LC3I decreased (Kabeya et al., 2000). It was proposed that during autophagy LC3I was process ...
... lysosomal enzyme inhibitors. The amount of the membraneassociated, 16 kDa LC3II increased at the same rate as the volume fraction of autophagic vacuoles in HeLa cells, while the amount of the soluble, 18 kDa LC3I decreased (Kabeya et al., 2000). It was proposed that during autophagy LC3I was process ...
4
... copolymer-conjugated doxorubicin via an enzymatically degradable bond (PK1) remain unclear. These conjugates were originally designed to release the drug from the oligopeptide side chain by the activity of lysosomal proteases (8). Some authors initially demonstrated that HPMA copolymer conjugates wi ...
... copolymer-conjugated doxorubicin via an enzymatically degradable bond (PK1) remain unclear. These conjugates were originally designed to release the drug from the oligopeptide side chain by the activity of lysosomal proteases (8). Some authors initially demonstrated that HPMA copolymer conjugates wi ...
Amyotrophic Lateral Sclerosis SOD1
... been involved in different neuropathologies with an inflammatory component, such as Alzheimer’s and Huntington’s diseases, multiple sclerosis, spinal cord injury, and neuropathic pain (15, 16). Recent articles reported that P2X7 receptor expression and modulation are linked to neuroinflammation in h ...
... been involved in different neuropathologies with an inflammatory component, such as Alzheimer’s and Huntington’s diseases, multiple sclerosis, spinal cord injury, and neuropathic pain (15, 16). Recent articles reported that P2X7 receptor expression and modulation are linked to neuroinflammation in h ...
The functional cobalamin (vitamin B12)–intrinsic factor receptor is a
... canine I-GS cases have abnormal processing and deficient apical membrane expression of cubilin.20 However, extensive genetic analyses of Norwegian and Middle Eastern kindreds24 as well as of canine I-GS cases25 have disclosed that the disease displays locus heterogeneity. Very recently, Tanner et al ...
... canine I-GS cases have abnormal processing and deficient apical membrane expression of cubilin.20 However, extensive genetic analyses of Norwegian and Middle Eastern kindreds24 as well as of canine I-GS cases25 have disclosed that the disease displays locus heterogeneity. Very recently, Tanner et al ...
Pleiotropy of leptin receptor signalling is defined by distinct roles of
... motif (YXXQ) [36], was exchanged for valine, which is found in this position in the Tyr1077 motif. A proline residue at P+2 has been proposed to be important for binding of STAT1 by the IL-6 receptor gp130 [37] and was exchanged for glycine. A consensus sequence for binding of STAT5 has not yet been ...
... motif (YXXQ) [36], was exchanged for valine, which is found in this position in the Tyr1077 motif. A proline residue at P+2 has been proposed to be important for binding of STAT1 by the IL-6 receptor gp130 [37] and was exchanged for glycine. A consensus sequence for binding of STAT5 has not yet been ...
An Integrated Chemical Biology Approach Identifies Specific
... Ewing’s sarcoma is a pediatric cancer of the bone that is characterized by the expression of the chimeric transcription factor EWS-FLI1 that confers a highly malignant phenotype and results from the chromosomal translocation t(11;22)(q24;q12). Poor overall survival and pronounced long-term side effe ...
... Ewing’s sarcoma is a pediatric cancer of the bone that is characterized by the expression of the chimeric transcription factor EWS-FLI1 that confers a highly malignant phenotype and results from the chromosomal translocation t(11;22)(q24;q12). Poor overall survival and pronounced long-term side effe ...
My Life with Dicty
... collect growing Dictyostelium amoebae and initiate synchronous development. For the next 24 hours my attention was totally focused on the developing cells as they aggregated, formed slugs, and culminated into fruiting bodies. I was enamored but did not realize for several years that it would be a li ...
... collect growing Dictyostelium amoebae and initiate synchronous development. For the next 24 hours my attention was totally focused on the developing cells as they aggregated, formed slugs, and culminated into fruiting bodies. I was enamored but did not realize for several years that it would be a li ...
Targeting Membrane-Bound Viral RNA Synthesis Reveals
... interact with viral particles thus inactivating their binding or cellentry activity. To clarify this possibility, the virus was incubated with ,70 IC50 doses of K22 or DMSO solvent for 15 min at 37uC, followed by virus dilution and its titration at non-inhibitory compound concentrations. Similar tit ...
... interact with viral particles thus inactivating their binding or cellentry activity. To clarify this possibility, the virus was incubated with ,70 IC50 doses of K22 or DMSO solvent for 15 min at 37uC, followed by virus dilution and its titration at non-inhibitory compound concentrations. Similar tit ...
Filling two-piece hard gelatin capsules with liquids
... evident in Figure 1, which compares the in vitro dissolution profiles of triamterene when formulated with different solubilizing excipients [13]. Formulating drug compounds in liquid or semi-solid excipients is also used to target lymphatic transport [14] or to circumvent the impact of transporters ...
... evident in Figure 1, which compares the in vitro dissolution profiles of triamterene when formulated with different solubilizing excipients [13]. Formulating drug compounds in liquid or semi-solid excipients is also used to target lymphatic transport [14] or to circumvent the impact of transporters ...
Biophys-85_R1
... causes ATP release, which leads to proliferation of adventitial fibroblasts of the pulmonary artery and induces transformation to myofibroblasts via autocrine/paracrine mechanisms [29], indicating the role of ATP in vascular remodeling in pulmonary arterial hypertension. A blockade of purine recepto ...
... causes ATP release, which leads to proliferation of adventitial fibroblasts of the pulmonary artery and induces transformation to myofibroblasts via autocrine/paracrine mechanisms [29], indicating the role of ATP in vascular remodeling in pulmonary arterial hypertension. A blockade of purine recepto ...
Chloroplast Tubules Visualized in Transplastomic Plants Expressing
... chloroplast tubules in mesophyll cells adjacent to the epidermal cells in some leaves (Fig. 4a). These observations suggest that chloroplast tubules may be regulated developmentally and/or tissue-specifically and have functions related to photosynthesis and the intracellular signal transduction. Pre ...
... chloroplast tubules in mesophyll cells adjacent to the epidermal cells in some leaves (Fig. 4a). These observations suggest that chloroplast tubules may be regulated developmentally and/or tissue-specifically and have functions related to photosynthesis and the intracellular signal transduction. Pre ...
Basic Research Grants Funded for 2012
... The role of vehicle coat protein alpha-COP in new models of SMA: Sara Custer, Ph.D., Indiana University for $140,000 for two years. Objective: This award supports Dr. Sara Custer's postdoctoral training in the lab of Dr. Elliot Androphy at the Indiana University School of Medicine. The main focus of ...
... The role of vehicle coat protein alpha-COP in new models of SMA: Sara Custer, Ph.D., Indiana University for $140,000 for two years. Objective: This award supports Dr. Sara Custer's postdoctoral training in the lab of Dr. Elliot Androphy at the Indiana University School of Medicine. The main focus of ...
Nup358 interacts with APC and plays a role in cell polarization
... Nathke et al., 1996). APC is also a tumor suppressor that is truncated in most colorectal cancers and has a well-established role in negatively regulating Wnt signaling by mediating the degradation of β-catenin (Bienz and Clevers, 2000; Nathke, 2004; Polakis, 2000). However, its role in microtubule ...
... Nathke et al., 1996). APC is also a tumor suppressor that is truncated in most colorectal cancers and has a well-established role in negatively regulating Wnt signaling by mediating the degradation of β-catenin (Bienz and Clevers, 2000; Nathke, 2004; Polakis, 2000). However, its role in microtubule ...
ABSTRACT SUSTAINED DELIVERY AND PHARMACODYNAMICS OF AN INTEGRIN
... therapies. Development of novel therapeutic agents provides effective treatment for ocular disorders. However, treatment of many posterior segment diseases like agerelated macular degeneration (AMD) and diabetic retinopathy (DRP) is far from satisfactory due to the limited availability of novel ther ...
... therapies. Development of novel therapeutic agents provides effective treatment for ocular disorders. However, treatment of many posterior segment diseases like agerelated macular degeneration (AMD) and diabetic retinopathy (DRP) is far from satisfactory due to the limited availability of novel ther ...
Novel role for the Lu/BCAM–spectrin interaction in actin cytoskeleton
... spectrin interaction, enhanced the half-life of Lu/BCAM at the MDCK (Madin–Darby canine kidney) cell surface, and increased Lu/BCAM-mediated cell adhesion and spreading on laminin 511/521. We have shown that the Lu/BCAM–spectrin interaction mediated actin reorganization during cell adhesion and spre ...
... spectrin interaction, enhanced the half-life of Lu/BCAM at the MDCK (Madin–Darby canine kidney) cell surface, and increased Lu/BCAM-mediated cell adhesion and spreading on laminin 511/521. We have shown that the Lu/BCAM–spectrin interaction mediated actin reorganization during cell adhesion and spre ...
ANTIGENS IN IMMUNITY XV. ULTRASZl~IlcroRAL
... reticular cell process. Fig. 5 shows that lymphocytes, too, can engender delicate cytoplasmic extensions and these when examined in transverse or tangential section, are not distinguishable from the more tenuous of reticular cell processes cut in similar plane. In fact in many cases, where a complex ...
... reticular cell process. Fig. 5 shows that lymphocytes, too, can engender delicate cytoplasmic extensions and these when examined in transverse or tangential section, are not distinguishable from the more tenuous of reticular cell processes cut in similar plane. In fact in many cases, where a complex ...
as PDF
... rests particularly with T and B-cells as they display the receptors capable of recognising non self molecules from the self. The specific attack is also complimented before by the strategic non specific immune responses generated by polymmorphonucelar cells, NKs, macrophages, co-stimulatory molecule ...
... rests particularly with T and B-cells as they display the receptors capable of recognising non self molecules from the self. The specific attack is also complimented before by the strategic non specific immune responses generated by polymmorphonucelar cells, NKs, macrophages, co-stimulatory molecule ...
Phage Therapy
... down the most lytic phage, and the phage that affected multiple strains of the mastitis causing bacteria. Eventually two phage were selected for analyses because of their high lytic ability towards over half of the 15 isolates of S. aureus[4]. This study demonstrates yet another medical application ...
... down the most lytic phage, and the phage that affected multiple strains of the mastitis causing bacteria. Eventually two phage were selected for analyses because of their high lytic ability towards over half of the 15 isolates of S. aureus[4]. This study demonstrates yet another medical application ...
Science Jeopardy - Broward County Public Schools
... (1) Save a duplicate of this template. (2) Enter all answers and questions in the normal view. (view/normal) (3) Change the category headings in the normal view (view/normal) (4) View as a slideshow. (5) Use the home red button after each question. ...
... (1) Save a duplicate of this template. (2) Enter all answers and questions in the normal view. (view/normal) (3) Change the category headings in the normal view (view/normal) (4) View as a slideshow. (5) Use the home red button after each question. ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.