CELL MOTILITY: Spatial and Temporal Regulation of
... leukocytes, fibroblasts, epithelial cells, and neuronal growth cones, fulfill their specific biological roles. Although these cells’ overall migration occurs through related molecular and cellular mechanisms, their types of movement are very distinct and are optimized to their specific environments. ...
... leukocytes, fibroblasts, epithelial cells, and neuronal growth cones, fulfill their specific biological roles. Although these cells’ overall migration occurs through related molecular and cellular mechanisms, their types of movement are very distinct and are optimized to their specific environments. ...
Reduce Formation of SLP-76 Linker of Activated T Cells and SLP
... microclusters (MCs). Despite marked inhibition of actin remodeling and cell spreading, the induction of MCs containing TCRCD3 or ZAP70 was not affected significantly by Nef. However, Nef potently inhibited the subsequent formation of MCs positive for the signaling adaptor Src homology-2 domain-conta ...
... microclusters (MCs). Despite marked inhibition of actin remodeling and cell spreading, the induction of MCs containing TCRCD3 or ZAP70 was not affected significantly by Nef. However, Nef potently inhibited the subsequent formation of MCs positive for the signaling adaptor Src homology-2 domain-conta ...
Biology I Pacing Guide
... Classify solutions as acidic, basic, or neutral and relate the significance of the pH scale on an organism’s survival (e.g., consequences of having different concentrations of hydrogen and hydroxide ions). (DOK 2) Compare and contrast the structure, properties, and principal functions of carbohydrat ...
... Classify solutions as acidic, basic, or neutral and relate the significance of the pH scale on an organism’s survival (e.g., consequences of having different concentrations of hydrogen and hydroxide ions). (DOK 2) Compare and contrast the structure, properties, and principal functions of carbohydrat ...
The Biology of Cancer Metastasis: Historical
... interrelated steps (Fig. 3), each of which can be rate limiting because a failure at any step may halt the process (16). The outcome of the process is dependent on both the intrinsic properties of the tumor cells and the host response, such that metastasis is a balance of host-tumor cellular interac ...
... interrelated steps (Fig. 3), each of which can be rate limiting because a failure at any step may halt the process (16). The outcome of the process is dependent on both the intrinsic properties of the tumor cells and the host response, such that metastasis is a balance of host-tumor cellular interac ...
Structure and Function of Membrane Proteins: Overview
... I. Cells are separated from the world by a thin, fragile structure, the plasma membrane – 5 – 10 nm thick A. ~10,000 plasma membranes stacked one on top of another would equal the thickness of a book's page B. No hint of a plasma membrane is detected in a thin section under a light microscope since ...
... I. Cells are separated from the world by a thin, fragile structure, the plasma membrane – 5 – 10 nm thick A. ~10,000 plasma membranes stacked one on top of another would equal the thickness of a book's page B. No hint of a plasma membrane is detected in a thin section under a light microscope since ...
Millius et al., J. Cell Sci., 2012 - Cardiovascular Research Institute
... Fig. 2. Actin and p40 retrograde flow is similar to WAVE2 retrograde flow. (A) Left panel shows epifluorescence image of an XTC cell expressing a low concentration of EGFP-tagged p40 subunit of the Arp2/3 complex (corresponds to supplementary material Movie 3). Scale bar: 5 mm. Middle panel shows ma ...
... Fig. 2. Actin and p40 retrograde flow is similar to WAVE2 retrograde flow. (A) Left panel shows epifluorescence image of an XTC cell expressing a low concentration of EGFP-tagged p40 subunit of the Arp2/3 complex (corresponds to supplementary material Movie 3). Scale bar: 5 mm. Middle panel shows ma ...
Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts,...
... (PS1NTF, MAB1563, Chemicon/Millipore, Billerica, MA, USA), C-terminal fragment of presenilin 1 (PS1CTF, 4627, gift from Dr. Michael Wolfe), Nicastrin (NCT, Sigma), and APH-1 (Affinity BioReagents, Cambridge, MA, USA). Although the specificity of anti-PS1NTF (amino acids 21–80 of human PS1) to monkey P ...
... (PS1NTF, MAB1563, Chemicon/Millipore, Billerica, MA, USA), C-terminal fragment of presenilin 1 (PS1CTF, 4627, gift from Dr. Michael Wolfe), Nicastrin (NCT, Sigma), and APH-1 (Affinity BioReagents, Cambridge, MA, USA). Although the specificity of anti-PS1NTF (amino acids 21–80 of human PS1) to monkey P ...
Bone physiology
... Junctional complexs (gap junctions) are often found between the osteoblasts. The plasma membrane of the osteoblast is characteristically rich in alkaline phosphatase (used as an index of bone formation) and been shown to have rceptors for parathyroid hormone, but not for calcitonin. ...
... Junctional complexs (gap junctions) are often found between the osteoblasts. The plasma membrane of the osteoblast is characteristically rich in alkaline phosphatase (used as an index of bone formation) and been shown to have rceptors for parathyroid hormone, but not for calcitonin. ...
Comparing The Effects of Small Molecules BIX
... Most of them may have more than one target and unexpected toxicity or other in vivo side-effects may thus interfere with their clinical application (10). To study the effects of VPA, BIX-01294, RG-108 and Bay K8644 on inducing the expression of pluripotency markers in vivo, we used them in different ...
... Most of them may have more than one target and unexpected toxicity or other in vivo side-effects may thus interfere with their clinical application (10). To study the effects of VPA, BIX-01294, RG-108 and Bay K8644 on inducing the expression of pluripotency markers in vivo, we used them in different ...
Biliary Atresia Is Associated with CD4 Th1 Cell
... Figure 1. Fluorescent immunohistochemistry reveals an increase in CD8⫹ T cells, CD3⫹/CD4⫹ T cells, and Kupffer cells in the portal tracts in biliary atresia. Frozen sections from normal liver (n ⫽ 4), other neonatal cholestatic liver diseases (TPN, n ⫽ 4; CDC, n ⫽ 1; NH, n ⫽ 3), and biliary atresia ...
... Figure 1. Fluorescent immunohistochemistry reveals an increase in CD8⫹ T cells, CD3⫹/CD4⫹ T cells, and Kupffer cells in the portal tracts in biliary atresia. Frozen sections from normal liver (n ⫽ 4), other neonatal cholestatic liver diseases (TPN, n ⫽ 4; CDC, n ⫽ 1; NH, n ⫽ 3), and biliary atresia ...
Biology I
... and precision in using graduated cylinders, balances, beakers, thermometers, and rulers *1b. Formulate questions that can be answered through research and experimental design. (DOK 3) *1c. Apply the components of scientific processes and methods in classroom and laboratory investigations (e.g., hypo ...
... and precision in using graduated cylinders, balances, beakers, thermometers, and rulers *1b. Formulate questions that can be answered through research and experimental design. (DOK 3) *1c. Apply the components of scientific processes and methods in classroom and laboratory investigations (e.g., hypo ...
Neutrophils injure cultured skeletal myotubes
... was included in the coculture medium to provide a substrate for nitric oxide synthesis and to enhance neutrophil degranulation (33). The final neutrophil preparation routinely yielded ⬎98% neutrophils with cell viability ⬎98% as determined by trypan blue exclusion. For the cytotoxicity assay, neutro ...
... was included in the coculture medium to provide a substrate for nitric oxide synthesis and to enhance neutrophil degranulation (33). The final neutrophil preparation routinely yielded ⬎98% neutrophils with cell viability ⬎98% as determined by trypan blue exclusion. For the cytotoxicity assay, neutro ...
Localisation of the Ki-67 antigen within the nucleolus
... Waseem and Lane, 1990). However, pKi-67 appears unique in that it associates with nucleoli of proliferating cells only and with chromosomes during mitosis. The nucleolus contains rRNA gene repeats and is the site of ribosome synthesis. Nucleoli display a unique higher-order structure (reviewed by Sc ...
... Waseem and Lane, 1990). However, pKi-67 appears unique in that it associates with nucleoli of proliferating cells only and with chromosomes during mitosis. The nucleolus contains rRNA gene repeats and is the site of ribosome synthesis. Nucleoli display a unique higher-order structure (reviewed by Sc ...
doc - 3.24 MB - Medicines for Malaria Venture
... hypnozoites is long overdue. In the absence of a clear understanding of the molecular mechanisms, the whole parasite is the best place to start such a search. Screening large collections of compounds against whole parasites is now a matter of course for P. falciparum [24], where ‘high content’ image ...
... hypnozoites is long overdue. In the absence of a clear understanding of the molecular mechanisms, the whole parasite is the best place to start such a search. Screening large collections of compounds against whole parasites is now a matter of course for P. falciparum [24], where ‘high content’ image ...
Pseudomonas spp.-induced systemic resistance
... 2002; Robert et al., 2002) and in response to elicitor molecules that enhance resistance against Botrytis cinerea and Plasmopara viticola (Aziz et al., 2006, 2007; Vandelle et al., 2006; Varnier et al., 2009). These defence responses comprise the oxidative burst characterized by the transient genera ...
... 2002; Robert et al., 2002) and in response to elicitor molecules that enhance resistance against Botrytis cinerea and Plasmopara viticola (Aziz et al., 2006, 2007; Vandelle et al., 2006; Varnier et al., 2009). These defence responses comprise the oxidative burst characterized by the transient genera ...
A model of chloroplast growth regulation in mesophyll cells
... Dockery and Keener (2001) based their quorum sensing model on the eight component gene-regulatory system described in Van Delden and Iglewski (1998). They simplified it down to two ordinary differential equations using time scale assumptions. We adopt the two variable model in this paper but conside ...
... Dockery and Keener (2001) based their quorum sensing model on the eight component gene-regulatory system described in Van Delden and Iglewski (1998). They simplified it down to two ordinary differential equations using time scale assumptions. We adopt the two variable model in this paper but conside ...
Polarity Control of Spindle Positioning in the C. elegans Embryo
... examples of niche-dependent asymmetric divisions. The mechanisms that control these divisions differ from the focus of this chapter and are therefore not discussed. Insight obtained in C. elegans studies has substantially contributed to the molecular understanding of asymmetric divisions in mammals, ...
... examples of niche-dependent asymmetric divisions. The mechanisms that control these divisions differ from the focus of this chapter and are therefore not discussed. Insight obtained in C. elegans studies has substantially contributed to the molecular understanding of asymmetric divisions in mammals, ...
Transient and Stable GFP Expression in Germ Cells by the vasa
... transgenic fish; consumers’ attitudes toward genetically modified fish. Red seabream (Pagrus major) is an economically important marine species in China. The methods for sperm cryopreservation of the fish have been developed successfully. However, little progress has been achieved in the embryo cryo ...
... transgenic fish; consumers’ attitudes toward genetically modified fish. Red seabream (Pagrus major) is an economically important marine species in China. The methods for sperm cryopreservation of the fish have been developed successfully. However, little progress has been achieved in the embryo cryo ...
INTRODUCCIÓN
... Prostaglandins (PGs) play a key role in the development on the immune response, through the regulation of both pro- and anti-inflammatory processes. PGD2 can be either proor anti-inflammatory depending on the inflammatory milieu. Prostaglandin D synthethase (PGDS) is the enzyme responsible for the c ...
... Prostaglandins (PGs) play a key role in the development on the immune response, through the regulation of both pro- and anti-inflammatory processes. PGD2 can be either proor anti-inflammatory depending on the inflammatory milieu. Prostaglandin D synthethase (PGDS) is the enzyme responsible for the c ...
The Functional Influence of Burst and Tonic Firing Mode on Synaptic
... PGN neurons that were monosynaptically connected with a simultaneously recorded LGNd cell resulted in IPSPs with a relatively fixed latency of ;1 msec. The mean amplitude of these single IPSPs varied considerably among different pairs of cells, ranging from just above the noise level (0.1– 0.2 mV) t ...
... PGN neurons that were monosynaptically connected with a simultaneously recorded LGNd cell resulted in IPSPs with a relatively fixed latency of ;1 msec. The mean amplitude of these single IPSPs varied considerably among different pairs of cells, ranging from just above the noise level (0.1– 0.2 mV) t ...
Tansley review - Professor Gero Steinberg
... A deeper understanding of the MT-based transport mechanisms that underlie polar growth and plant infection requires detailed knowledge of the cellular organization of the cytoskeleton. Intensive work along these lines in U. maydis has been undertaken. Unexpectedly, these studies reveal that molecula ...
... A deeper understanding of the MT-based transport mechanisms that underlie polar growth and plant infection requires detailed knowledge of the cellular organization of the cytoskeleton. Intensive work along these lines in U. maydis has been undertaken. Unexpectedly, these studies reveal that molecula ...
Tracheary element evolution
... tubes are further classified into sieve cells and sieve tube elements (or members). Sieve cell: A long slender element, with relatively unspecialized sieve areas, with tapering end walls that lack sieve plates; found in the phloem of gymnosperms. Sieve tube element (member): One of the component cel ...
... tubes are further classified into sieve cells and sieve tube elements (or members). Sieve cell: A long slender element, with relatively unspecialized sieve areas, with tapering end walls that lack sieve plates; found in the phloem of gymnosperms. Sieve tube element (member): One of the component cel ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.