The Induction of 72-kD Gelatinase in T Cells upon Adhesion to
... The mechanisms by which T cells actively invade the perivascular tissue are virtually unknown. We show here that the binding of cloned MBP-specific Thl cells to VCAM-1 on endothelial cells induces the expression of 72-kD gelatinase in T cells. In the experiments presented here, T cells were cocultur ...
... The mechanisms by which T cells actively invade the perivascular tissue are virtually unknown. We show here that the binding of cloned MBP-specific Thl cells to VCAM-1 on endothelial cells induces the expression of 72-kD gelatinase in T cells. In the experiments presented here, T cells were cocultur ...
TRANSMEMBRANE ADAPTOR PROTEINS: ORGANIZERS OF
... Most transmembrane proteins are excluded from rafts. However, several lipidmodified molecules can be found in rafts5, including the following: the co-receptors CD4 and CD8; the adhesion receptor CD44; members of the tumour-necrosis-factorreceptor family; and various transmembrane adaptor proteins (T ...
... Most transmembrane proteins are excluded from rafts. However, several lipidmodified molecules can be found in rafts5, including the following: the co-receptors CD4 and CD8; the adhesion receptor CD44; members of the tumour-necrosis-factorreceptor family; and various transmembrane adaptor proteins (T ...
Mutations in Actin-Related Proteins 2 and 3 Affect Cell Shape
... WRM and DIS1 Genes Are Integral Components of the ARP2/3 Complex Based on the mutations, the protein truncations in wrm1-2, dis1-1, and dis1-2 would be predicted to occur after amino acids 14, 97, and 290, respectively (Figure 1C). The G-to-A change in wrm1-1 results in the alteration of a conserved ...
... WRM and DIS1 Genes Are Integral Components of the ARP2/3 Complex Based on the mutations, the protein truncations in wrm1-2, dis1-1, and dis1-2 would be predicted to occur after amino acids 14, 97, and 290, respectively (Figure 1C). The G-to-A change in wrm1-1 results in the alteration of a conserved ...
Mesoderm migration in the Xenopus gastrula
... its adhesive properties, its more specific role in mesoderm migration is the induction of lamellipodium formation. In this way, the SCR substrate not only provides adhesiveness and resistance to mesoderm cell traction, but also regulates the protrusive activities of migrating cells. Migrating mesode ...
... its adhesive properties, its more specific role in mesoderm migration is the induction of lamellipodium formation. In this way, the SCR substrate not only provides adhesiveness and resistance to mesoderm cell traction, but also regulates the protrusive activities of migrating cells. Migrating mesode ...
Cell Lineage and Fate Map of the Primary
... of early development known as spiral cleavage. Animals with spiral cleavage have diverse body plans, and homologous embryonic cells can be readily identified among distantly related animals. Spiralian embryos are particularly amenable to studies of fate-mapping, and larval fates of identified cells ...
... of early development known as spiral cleavage. Animals with spiral cleavage have diverse body plans, and homologous embryonic cells can be readily identified among distantly related animals. Spiralian embryos are particularly amenable to studies of fate-mapping, and larval fates of identified cells ...
The lysosomal signaling anchor p18/LAMTOR1 controls epidermal
... cornified cell envelope composed of involucrin and loricrin, which are cross-linked by transglutaminase 1 (TGM1) and covalently bound to lipids. The inter-corneocyte space is filled mostly with ceramides and cholesterol, as well as several catabolic enzymes that are secreted from granular cells via ...
... cornified cell envelope composed of involucrin and loricrin, which are cross-linked by transglutaminase 1 (TGM1) and covalently bound to lipids. The inter-corneocyte space is filled mostly with ceramides and cholesterol, as well as several catabolic enzymes that are secreted from granular cells via ...
Discs large 5, an Essential Gene in Drosophila, Regulates Egg
... detected in 40% of ovarioles (150 ovarioles) (Figure 2C). Transient ...
... detected in 40% of ovarioles (150 ovarioles) (Figure 2C). Transient ...
3. Taxonomy and classification of Algae
... singled and equidistant, in contrast to prochlorophytes and most other algae, but similar to Rhodopyta and Glaucophyta. The reserve polysaccharide is cyanophycean starch, stored in tiny granules lying between the thylakoids. In addition, these cells often contain cyanophycin granules, that is, polym ...
... singled and equidistant, in contrast to prochlorophytes and most other algae, but similar to Rhodopyta and Glaucophyta. The reserve polysaccharide is cyanophycean starch, stored in tiny granules lying between the thylakoids. In addition, these cells often contain cyanophycin granules, that is, polym ...
About Lung Carcinoid Tumors What Are Lung Carcinoid Tumors?
... prove to be more potent than current drugs such as octreotide and lanreotide. Another new approach is to pair drugs similar to octreotide with a radioactive atom. These drugs are like those used for some radionuclide scans, but the radiation is stronger. The drugs bind to the carcinoid cells, delive ...
... prove to be more potent than current drugs such as octreotide and lanreotide. Another new approach is to pair drugs similar to octreotide with a radioactive atom. These drugs are like those used for some radionuclide scans, but the radiation is stronger. The drugs bind to the carcinoid cells, delive ...
Quantitative Receptor Binding Assay of Interleukin
... strictly require 37 °C as an incubation temperature since the thymocytes must be cultured at least 3 days. Receptor binding assay, on the other hand, which could be completed in I h, remained successful in the temperatures above 25 °C up to 45 °C. Receptor binding assay could also be applied to the ...
... strictly require 37 °C as an incubation temperature since the thymocytes must be cultured at least 3 days. Receptor binding assay, on the other hand, which could be completed in I h, remained successful in the temperatures above 25 °C up to 45 °C. Receptor binding assay could also be applied to the ...
Some Characteristics of an Early Protein (ICP 22) Synthesized in
... unabated during this period. Other polypeptides not discussed here are identified in Fig. 5 in order to allow comparison with earlier work using the same electrophoresis system. Modification of lCP 22 The autoradiograms in Fig. 3 and 4 suggested that the post-translational modification of ICP 22 to ...
... unabated during this period. Other polypeptides not discussed here are identified in Fig. 5 in order to allow comparison with earlier work using the same electrophoresis system. Modification of lCP 22 The autoradiograms in Fig. 3 and 4 suggested that the post-translational modification of ICP 22 to ...
Staining
... Tissue is cut in slides of one cell layer, it means 4-10mm. Tissue is translucent and „well- readable“ in this case Devices that are used for cutting are called microtomes. Tissue slices are put on slide. They are stretched out by heat, and stick by egg whiteglycerin ...
... Tissue is cut in slides of one cell layer, it means 4-10mm. Tissue is translucent and „well- readable“ in this case Devices that are used for cutting are called microtomes. Tissue slices are put on slide. They are stretched out by heat, and stick by egg whiteglycerin ...
Changes in Cell Morphology and the Cellular Localization of Protein
... things—and the crux of what makes fission yeast so valuable as a model organism— essential cellular processes are extremely well conserved. The likelihood that a mutation ...
... things—and the crux of what makes fission yeast so valuable as a model organism— essential cellular processes are extremely well conserved. The likelihood that a mutation ...
The F8H Glycosyltransferase is a Functional Paralog of FRA8
... of rhamnose to O2 of galacturonic acid (GalA) using UDPβ-L-rhamnose (Peña et al. 2007). The poplar wood-associated PoGT47C glycosyltransferase is a functional ortholog of the Arabidopsis FRA8 because overexpression of PoGT47C in the fra8 mutant rescues the GX deficiency caused by the fra8 mutation (Z ...
... of rhamnose to O2 of galacturonic acid (GalA) using UDPβ-L-rhamnose (Peña et al. 2007). The poplar wood-associated PoGT47C glycosyltransferase is a functional ortholog of the Arabidopsis FRA8 because overexpression of PoGT47C in the fra8 mutant rescues the GX deficiency caused by the fra8 mutation (Z ...
Diffusion of Green Fluorescent Protein in Three Cell
... E. coli strains. The strains of E. coli used were all derivatives of the parental strain MC4100, which was selected for arabinose resistance (MC4100AR) (2). The GFP gene was GFPmut3* (6). GFP constructs were expressed using the arabinose-inducible pBAD24 vector (10). The TatA-GFP construct is descri ...
... E. coli strains. The strains of E. coli used were all derivatives of the parental strain MC4100, which was selected for arabinose resistance (MC4100AR) (2). The GFP gene was GFPmut3* (6). GFP constructs were expressed using the arabinose-inducible pBAD24 vector (10). The TatA-GFP construct is descri ...
Topic: Reproduction Aim: Describe the stages of embryonic
... Following fertilization, the zygote moves through the oviduct propelled by involuntary smooth muscle contractions and by the cilia lining the oviduct. Around 30 hours after fertilization, the zygote undergoes its first mitosis and cell division. This process, called cleavage, continues, and by the t ...
... Following fertilization, the zygote moves through the oviduct propelled by involuntary smooth muscle contractions and by the cilia lining the oviduct. Around 30 hours after fertilization, the zygote undergoes its first mitosis and cell division. This process, called cleavage, continues, and by the t ...
MLAB 1415-Hematology Keri Brophy
... – Occurs if hemopexin and haptoglobin is depleted. Free hgb circulates in blood. 2. Hemoglobinuria – Occurs if free hgb can not be absorbed by the liver and kidney 3. Hemosiderinuria • Hemosiderin in the urine, sign of filtration of hemoglobin thru the kidney ...
... – Occurs if hemopexin and haptoglobin is depleted. Free hgb circulates in blood. 2. Hemoglobinuria – Occurs if free hgb can not be absorbed by the liver and kidney 3. Hemosiderinuria • Hemosiderin in the urine, sign of filtration of hemoglobin thru the kidney ...
Caveolin-3 and SAP97 form a scaffolding protein complex that
... shown). Therefore, the Cav-3 that was pulled down from heart extracts by GST1.5C1 likely represents the fraction bound to SAP97. The interaction between SAP97 and Cav-3 was confirmed in cotransfection experiments and in vitro. Figure 1C shows that anti-PDZ antibody specifically coprecipitated Cav-3 ...
... shown). Therefore, the Cav-3 that was pulled down from heart extracts by GST1.5C1 likely represents the fraction bound to SAP97. The interaction between SAP97 and Cav-3 was confirmed in cotransfection experiments and in vitro. Figure 1C shows that anti-PDZ antibody specifically coprecipitated Cav-3 ...
Comparison of Properties of Medial Entorhinal Cortex
... Mechanisms underlying grid cell firing in the medial entorhinal cortex (MEC) still remain unknown. Computational modeling studies have suggested that cellular properties such as spike frequency adaptation and persistent firing might underlie the grid cell firing. Recent in vivo studies also suggest ...
... Mechanisms underlying grid cell firing in the medial entorhinal cortex (MEC) still remain unknown. Computational modeling studies have suggested that cellular properties such as spike frequency adaptation and persistent firing might underlie the grid cell firing. Recent in vivo studies also suggest ...
Androgens Down-Regulate bcl-2 Protooncogene Expression in ZR
... breast cancer growth in a proportion of women comparable to that achieved with other endocrine therapies. In fact, a direct growth inhibitory effect of androgens has been demonstrated in estrogen-responsive ZR-75-1 human breast cancer cells under both basal and estrogen-induced incubation conditions ...
... breast cancer growth in a proportion of women comparable to that achieved with other endocrine therapies. In fact, a direct growth inhibitory effect of androgens has been demonstrated in estrogen-responsive ZR-75-1 human breast cancer cells under both basal and estrogen-induced incubation conditions ...
Formative Cell Divisions: Principal Determinants of Plant
... A relay of coordinated oriented cell divisions involving precise cell division plane switches gradually transforms the fertilized egg cell into an embryo by determining the fates and positions of cells, patterning tissues and creating organs. Therefore, oriented cell divisions form ‘principal determ ...
... A relay of coordinated oriented cell divisions involving precise cell division plane switches gradually transforms the fertilized egg cell into an embryo by determining the fates and positions of cells, patterning tissues and creating organs. Therefore, oriented cell divisions form ‘principal determ ...
Klebsiella pneumoniae survives within macrophages by
... of 100:1. However, these conditions also triggered a significant decrease in cell viability as detected ...
... of 100:1. However, these conditions also triggered a significant decrease in cell viability as detected ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.