Research Interests
... morphogenesis. Repeated pair-wise changes in these morphogenic characters (from cellular processes to patterning elements) that are phylogenetically correlated will suggest hypotheses of functional relationships between the correlated characters that can then be tested. Likewise, variations in a mo ...
... morphogenesis. Repeated pair-wise changes in these morphogenic characters (from cellular processes to patterning elements) that are phylogenetically correlated will suggest hypotheses of functional relationships between the correlated characters that can then be tested. Likewise, variations in a mo ...
The Role of Intracellular Signaling Pathways in the Pathogenesis of
... cytokines, such as TNF-α, IL-1β, and CD40, as well as chemokines and cell adhesion molecules. NF-κB plays an important role in controlling expression of cytokines, cell adhesion molecules, and molecules involved in resistance to cell death. NF-κB is activated in many types of cancer, including MM, a ...
... cytokines, such as TNF-α, IL-1β, and CD40, as well as chemokines and cell adhesion molecules. NF-κB plays an important role in controlling expression of cytokines, cell adhesion molecules, and molecules involved in resistance to cell death. NF-κB is activated in many types of cancer, including MM, a ...
Early Morphogenesis of the Caenorhabditis elegans Pharynx
... Prior to pharyngeal extension, the pharyngeal cells appear wedge-shaped with their apical surfaces, as defined by JAM-1::GFP expression, located at the tip of the wedge and their basolateral compartment extending over the remaining surfaces (Figs. 3A, 3C, and 3E). The cells’ apicobasal polarity is a ...
... Prior to pharyngeal extension, the pharyngeal cells appear wedge-shaped with their apical surfaces, as defined by JAM-1::GFP expression, located at the tip of the wedge and their basolateral compartment extending over the remaining surfaces (Figs. 3A, 3C, and 3E). The cells’ apicobasal polarity is a ...
Cell Lineage and Fate Map of the Primary Somatoblast of the
... of early development known as spiral cleavage. Animals with spiral cleavage have diverse body plans, and homologous embryonic cells can be readily identified among distantly related animals. Spiralian embryos are particularly amenable to studies of fate-mapping, and larval fates of identified cells ...
... of early development known as spiral cleavage. Animals with spiral cleavage have diverse body plans, and homologous embryonic cells can be readily identified among distantly related animals. Spiralian embryos are particularly amenable to studies of fate-mapping, and larval fates of identified cells ...
Fate of primitive streak cells
... The regionalization of mesoderm precursors in the PS The developmental fate of cells in the PS of the gastrulating embryo was analyzed by tracing the distribution of DiI- or DiO-labeled cells and the pattern of tissue colonization displayed by graft-derived lacZ- or GFP-expressing cells. The results ...
... The regionalization of mesoderm precursors in the PS The developmental fate of cells in the PS of the gastrulating embryo was analyzed by tracing the distribution of DiI- or DiO-labeled cells and the pattern of tissue colonization displayed by graft-derived lacZ- or GFP-expressing cells. The results ...
The cortical cytoskeletal network and cell-wall
... such a way that it serves as a focal point for later division-related events such as mitosis and cytokinesis. Although the function of the PPB remains largely unresolved, it apparently leaves a positional imprint in the form of proteins such as MOR1, TON1 and FASS/TON2/DCD1, which consistently local ...
... such a way that it serves as a focal point for later division-related events such as mitosis and cytokinesis. Although the function of the PPB remains largely unresolved, it apparently leaves a positional imprint in the form of proteins such as MOR1, TON1 and FASS/TON2/DCD1, which consistently local ...
Human Placenta Is a Potent Hematopoietic
... becomes hematopoietic. The emergence of multipotent progenitors and HSCs, organized in clusters of cells closely adherent to the ventral wall of the dorsal aorta, starts at day 27 in the developing splanchnopleura/AGM region (Tavian et al., 1996, 1999, 2001). Starting at day 30, the first erythroid ...
... becomes hematopoietic. The emergence of multipotent progenitors and HSCs, organized in clusters of cells closely adherent to the ventral wall of the dorsal aorta, starts at day 27 in the developing splanchnopleura/AGM region (Tavian et al., 1996, 1999, 2001). Starting at day 30, the first erythroid ...
produced in photosynthesis
... Typical, or C3 photosynthesis is carried out by most plants growing in areas with sufficient water. In this type of photosynthesis, an enzyme called RuBP carboxylase grabs CO2 in the light independent reactions of photosynthesis. This works fine as long as there is plenty of carbon dioxide and rela ...
... Typical, or C3 photosynthesis is carried out by most plants growing in areas with sufficient water. In this type of photosynthesis, an enzyme called RuBP carboxylase grabs CO2 in the light independent reactions of photosynthesis. This works fine as long as there is plenty of carbon dioxide and rela ...
Merotelic kinetochore orientation occurs frequently during early
... Accepted 19 June 2003 Journal of Cell Science 116, 4213-4225 © 2003 The Company of Biologists Ltd doi:10.1242/jcs.00716 ...
... Accepted 19 June 2003 Journal of Cell Science 116, 4213-4225 © 2003 The Company of Biologists Ltd doi:10.1242/jcs.00716 ...
Annexure A: Ethical approval 116
... was diluted to 300 µM in PBS, 50 µl of which was added to 50 µl of PBS in each well to obtain a final concentration of 150 µM. JC-1 JC-1 in powder form was purchased from Sigma-Aldrich (St Louis, USA). A 1 mM stock solution was prepared in DMSO and stored at -70°C. Prior to use, the stock solution w ...
... was diluted to 300 µM in PBS, 50 µl of which was added to 50 µl of PBS in each well to obtain a final concentration of 150 µM. JC-1 JC-1 in powder form was purchased from Sigma-Aldrich (St Louis, USA). A 1 mM stock solution was prepared in DMSO and stored at -70°C. Prior to use, the stock solution w ...
REVIEWS - BioNMR Lab @ USTC
... into SYNGENEIC mice, caused dose-dependent inhibition of tumour growth14. In nude mice implanted with KU812 cells, oral treatment with 160 mg kg–1 daily in three divided doses for 11 consecutive days was associated with continuous blockage of p210BCR–ABL tyrosine phosphorylation, and resulted in tum ...
... into SYNGENEIC mice, caused dose-dependent inhibition of tumour growth14. In nude mice implanted with KU812 cells, oral treatment with 160 mg kg–1 daily in three divided doses for 11 consecutive days was associated with continuous blockage of p210BCR–ABL tyrosine phosphorylation, and resulted in tum ...
Fulltext: english, pdf
... toremifene and tamoxifen inhibited mitogen-induced proliferation and up-regulated tumor necrosis factor (TNF) receptor family molecules (36). Conversely, tamoxifen was shown to be stimulatory for TNFa production in cultures of normal human peripheral mononuclear blood cells, but this feature was abs ...
... toremifene and tamoxifen inhibited mitogen-induced proliferation and up-regulated tumor necrosis factor (TNF) receptor family molecules (36). Conversely, tamoxifen was shown to be stimulatory for TNFa production in cultures of normal human peripheral mononuclear blood cells, but this feature was abs ...
Immunological profile and aspects of immunotherapy in type 1 diabetes Maria Hjorth
... children induced a better preservation of endogenous insulin secretion compared with placebo. Here, we demonstrate that the treatment induced an early GAD65-specific Th2 and regulatory immune profile. After a few months, and still after more than two years, the recall response to GAD65 was character ...
... children induced a better preservation of endogenous insulin secretion compared with placebo. Here, we demonstrate that the treatment induced an early GAD65-specific Th2 and regulatory immune profile. After a few months, and still after more than two years, the recall response to GAD65 was character ...
classification of connective tissue
... small cells that contain a centrally-placed nucleus and large numbers of mitochondria. Brown adipocytes are multilocular cells, i.e., each cell contains multiple small lipid droplets. ...
... small cells that contain a centrally-placed nucleus and large numbers of mitochondria. Brown adipocytes are multilocular cells, i.e., each cell contains multiple small lipid droplets. ...
Promega Notes 99: NIH Chemical Genomics Center: Small
... www.NCGC.nih.gov), created in 2004, is part of the Molecular Libraries Screening Center Network (MLSCN), which is a network of screening centers created to discover small molecules for fundamental biological research as well to validate drug targets. NCGC optimizes high-throughput cellularbased and ...
... www.NCGC.nih.gov), created in 2004, is part of the Molecular Libraries Screening Center Network (MLSCN), which is a network of screening centers created to discover small molecules for fundamental biological research as well to validate drug targets. NCGC optimizes high-throughput cellularbased and ...
Surface CD81 Via Microparticles Release and Intercellular Transfer
... CD81 levels were markedly reduced on freshly isolated human T cells upon activation with anti-CD3 and anti-CD28 mAbs (Fig. 1B, upper panel). A similar reduction was observed on human tonsillar B cells after activation with anti-IgM mAbs and IL-4 (Fig. 1B, lower panel). Flow cytometric analysis with ...
... CD81 levels were markedly reduced on freshly isolated human T cells upon activation with anti-CD3 and anti-CD28 mAbs (Fig. 1B, upper panel). A similar reduction was observed on human tonsillar B cells after activation with anti-IgM mAbs and IL-4 (Fig. 1B, lower panel). Flow cytometric analysis with ...
Massive Expansion of Antigen-Specific CD8 T Cells during an Acute
... LCMV-specific CD81 cells at the peak of the immune response to LCMV, we adoptively transferred unstimulated, LCMV-specific TCR-transgenic T cells into host mice and infected them with LCMV. Similar methods have been used to follow the in vivo behavior of both CD41 and CD81 T cells (Zimmerman et al., ...
... LCMV-specific CD81 cells at the peak of the immune response to LCMV, we adoptively transferred unstimulated, LCMV-specific TCR-transgenic T cells into host mice and infected them with LCMV. Similar methods have been used to follow the in vivo behavior of both CD41 and CD81 T cells (Zimmerman et al., ...
Taddei-Peters, Marissa A. Miller, Yoshifumi Naka, Emilia Bagiella
... intramyocardial implantation of a single low dose of allogeneic mesenchymal precursor cells (MPCs) together with assessment of left ventricular performance during short intervals of ...
... intramyocardial implantation of a single low dose of allogeneic mesenchymal precursor cells (MPCs) together with assessment of left ventricular performance during short intervals of ...
Teacher Guide for Amplify Cell Structure and Function Module
... because the cell must take in some molecules from the body and produce some molecules for the body. Also note that some molecules stay within the cell. » Project the cellular input/output image on the board and fill it out during the discussion. (Afterward, students will complete the same worksheet ...
... because the cell must take in some molecules from the body and produce some molecules for the body. Also note that some molecules stay within the cell. » Project the cellular input/output image on the board and fill it out during the discussion. (Afterward, students will complete the same worksheet ...
Responses Mediated Downregulation of B Cell
... Alter-Wolf, Michelle Ratliff, Ana Marie Landin, Richard L. Riley and Bonnie B. Blomberg ...
... Alter-Wolf, Michelle Ratliff, Ana Marie Landin, Richard L. Riley and Bonnie B. Blomberg ...
Differing Infection Patterns of Dengue and Yellow Fever Viruses in a
... which may correspond to apoptotic hepatocytes [7], are observed in both infections [2]. It is not known whether the differences in the extent of pathologic changes induced by these two viruses in the liver are due to different cytopathic events in the hepatocytes. In YF virus infection, damage to he ...
... which may correspond to apoptotic hepatocytes [7], are observed in both infections [2]. It is not known whether the differences in the extent of pathologic changes induced by these two viruses in the liver are due to different cytopathic events in the hepatocytes. In YF virus infection, damage to he ...
Two classic cadherin-related molecules with no cadherin
... sequence homologous to the known classic cadherin CPs (Figs 1, 2). The amino acid sequence of this new cadherin was easily aligned to that of Bb-cadherin and no large gaps were observed (Fig. 2A). Bb-cadherin was then renamed Bb1-cadherin (Bb1C) and the new cadherin was designated as Bb2-cadherin (B ...
... sequence homologous to the known classic cadherin CPs (Figs 1, 2). The amino acid sequence of this new cadherin was easily aligned to that of Bb-cadherin and no large gaps were observed (Fig. 2A). Bb-cadherin was then renamed Bb1-cadherin (Bb1C) and the new cadherin was designated as Bb2-cadherin (B ...
Infectious Diseases in Obstetrics and Gynecology Vol. 2008, Article
... against G. vaginalis, but not against the tested healthy vaginal microbiota of lactobacilli. After conducting tissue sensitivity assays using an ectocervical tissue model, we determined that human cells remained viable after prolonged exposures to partially-purified subtilosin, indicating the compou ...
... against G. vaginalis, but not against the tested healthy vaginal microbiota of lactobacilli. After conducting tissue sensitivity assays using an ectocervical tissue model, we determined that human cells remained viable after prolonged exposures to partially-purified subtilosin, indicating the compou ...
Ameba Coloring
... don't fit into the other kingdoms. Some protozoans are considered plant-like while others are considered animallike. The ameba is considered an animal-like protist because it moves and consumes its food. Protists are classified by how they move, some have cilia or flagella, but the ameba has an unus ...
... don't fit into the other kingdoms. Some protozoans are considered plant-like while others are considered animallike. The ameba is considered an animal-like protist because it moves and consumes its food. Protists are classified by how they move, some have cilia or flagella, but the ameba has an unus ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.