Gene Section BTK (Bruton agammaglobulinemia tyrosine kinase) Atlas of Genetics and Cytogenetics
... Clinical manifestations of XLA XLA Patients have less than 1% of the normal number of peripheral B cells. Serum levels of all Ig classes are very low due to the lack of plasma cells in the secondary lymphoid organs. In XLA patients, B cell development is almost completely arrested at the pre-B cell ...
... Clinical manifestations of XLA XLA Patients have less than 1% of the normal number of peripheral B cells. Serum levels of all Ig classes are very low due to the lack of plasma cells in the secondary lymphoid organs. In XLA patients, B cell development is almost completely arrested at the pre-B cell ...
Suppression of inducible nitric oxide synthase expression in RAW
... to regulate the adverse effects of excessive NO Žfor review, see Fukuto and Chaudhuri, 1995.. Almost all of the developed inhibitors are substrate analogues for NOS, and they act as competitive inhibitors with little specificity for NOS isoforms. This lack of specificity restricts their use as thera ...
... to regulate the adverse effects of excessive NO Žfor review, see Fukuto and Chaudhuri, 1995.. Almost all of the developed inhibitors are substrate analogues for NOS, and they act as competitive inhibitors with little specificity for NOS isoforms. This lack of specificity restricts their use as thera ...
Exocytosis and cell polarity in plants exocyst and recycling domains
... been documented recently in tobacco. Endocytosed nanogold particles first enter the early endosome compartment with a tubulo-vesicular structure, and pulse-chase experiments have proven that most of the internalized marker is recycled back to the plasma membrane (Onelli et al., 2008). Several differ ...
... been documented recently in tobacco. Endocytosed nanogold particles first enter the early endosome compartment with a tubulo-vesicular structure, and pulse-chase experiments have proven that most of the internalized marker is recycled back to the plasma membrane (Onelli et al., 2008). Several differ ...
MAIT Cells Precursor Derivatives Activating Mouse Derived Riboflavin
... It was suggested that human MAIT cells display different patterns of reactivity toward different microbes that all harbor a functional riboflavin biosynthesis pathway (Mycobacterium smegmatis, Salmonella typhimurium, and Candida albicans) (11). TCR repertoire analysis of polyclonal human Va7.2+ (TRA ...
... It was suggested that human MAIT cells display different patterns of reactivity toward different microbes that all harbor a functional riboflavin biosynthesis pathway (Mycobacterium smegmatis, Salmonella typhimurium, and Candida albicans) (11). TCR repertoire analysis of polyclonal human Va7.2+ (TRA ...
Brucella Intracellular Replication Requires Trafficking Through the
... these experiments. Altogether, the previous studies support a model of BCV trafficking through early endocytic compartments, but because of the technical limitations associated with these studies, a role for late endosomes/ lysosomes cannot be excluded. The current model of BCV segregation from the ...
... these experiments. Altogether, the previous studies support a model of BCV trafficking through early endocytic compartments, but because of the technical limitations associated with these studies, a role for late endosomes/ lysosomes cannot be excluded. The current model of BCV segregation from the ...
Progressive induction of caudal neural character by graded Wnt
... to axis duplications and/or other malformations of the embrynature neuroscience • volume 5 no 6 • june 2002 ...
... to axis duplications and/or other malformations of the embrynature neuroscience • volume 5 no 6 • june 2002 ...
Cyproheptadine displays preclinical activity in
... novel therapeutic agent for the treatment of malignancy. Because the drug is well tolerated and already approved in multiple countries for clinical use as an antihistamine and appetite stimulant, it could be moved directly into clinical trials for cancer. (Blood. 2008;112:760-769) ...
... novel therapeutic agent for the treatment of malignancy. Because the drug is well tolerated and already approved in multiple countries for clinical use as an antihistamine and appetite stimulant, it could be moved directly into clinical trials for cancer. (Blood. 2008;112:760-769) ...
Growth and killing of a Salmonella enterica serovar
... have an effect on the set of bacterial genes expressed at the moment of their introduction into the cytosol, and therefore on the bacterial response. This second method has been applied to deliver S. typhimurium, Yersinia enterocolitica and non-pathogenic E. coli into the cytosol of epithelial cells ...
... have an effect on the set of bacterial genes expressed at the moment of their introduction into the cytosol, and therefore on the bacterial response. This second method has been applied to deliver S. typhimurium, Yersinia enterocolitica and non-pathogenic E. coli into the cytosol of epithelial cells ...
Morphology and physiology of the marine straminipilan fungi, the
... the equatorial Indian Ocean. None of the samples yielded thraustochytrids in culture, suggesting that aplanochytrids might be more prevalent in the zooplankton samples of these waters than thraustochytrids. Fourteen isolates of aplanochytrids were studied with reference to their colony and cell morp ...
... the equatorial Indian Ocean. None of the samples yielded thraustochytrids in culture, suggesting that aplanochytrids might be more prevalent in the zooplankton samples of these waters than thraustochytrids. Fourteen isolates of aplanochytrids were studied with reference to their colony and cell morp ...
7-2 cell parts
... Ribosomes are small particles of RNA and protein found throughout the cytoplasm and attached to other organelles. Slide 16 of 49 Copyright Pearson Prentice Hall ...
... Ribosomes are small particles of RNA and protein found throughout the cytoplasm and attached to other organelles. Slide 16 of 49 Copyright Pearson Prentice Hall ...
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... eRNAi complements the global affects of pRNAi by facilitating gene knockdown in specific cells, in the context of other cells in the tissue, and at later developmental stages. Two different approaches have been developed to knock down gene expression using eRNAi in Parasteatoda. Pechmann and colleag ...
... eRNAi complements the global affects of pRNAi by facilitating gene knockdown in specific cells, in the context of other cells in the tissue, and at later developmental stages. Two different approaches have been developed to knock down gene expression using eRNAi in Parasteatoda. Pechmann and colleag ...
the spider Parasteatoda tepidariorum
... eRNAi complements the global affects of pRNAi by facilitating gene knockdown in specific cells, in the context of other cells in the tissue, and at later developmental stages. Two different approaches have been developed to knock down gene expression using eRNAi in Parasteatoda. Pechmann and colleag ...
... eRNAi complements the global affects of pRNAi by facilitating gene knockdown in specific cells, in the context of other cells in the tissue, and at later developmental stages. Two different approaches have been developed to knock down gene expression using eRNAi in Parasteatoda. Pechmann and colleag ...
Aluminum-Induced 133-ß-D-Glucan Inhibits Cell
... 2020 (Gruhn et al., 1995). Al rapidly inhibits root elongation depending on the Al concentration. Subsequently, this prevents development of the ramified root system, an essential feature for successful plant development (Kochian, 1995). The primary target of Al toxicity is unknown yet, when both ap ...
... 2020 (Gruhn et al., 1995). Al rapidly inhibits root elongation depending on the Al concentration. Subsequently, this prevents development of the ramified root system, an essential feature for successful plant development (Kochian, 1995). The primary target of Al toxicity is unknown yet, when both ap ...
Detoxification of Arsenic by Phytochelatins in Plants
... ration of As into organic molecules by the formation of e.g. arsenocholine, arsenobetaine, or arsenosugars. In bacteria, a widespread tolerance mechanism for arsenate, AsVO43⫺, is based on an efflux system that exports arsenic specifically and ATP-dependently as AsIIIO2⫺ from the cell generated by c ...
... ration of As into organic molecules by the formation of e.g. arsenocholine, arsenobetaine, or arsenosugars. In bacteria, a widespread tolerance mechanism for arsenate, AsVO43⫺, is based on an efflux system that exports arsenic specifically and ATP-dependently as AsIIIO2⫺ from the cell generated by c ...
Expansion of the phragmoplast during plant cytokinesis: a MAPK
... details of cell-plate maturation have been revealed through the observation of cryofixed tobacco cells by Samuels et al. [5] (Figure 1a). Vesicles fuse via long thin (i.e. 20 nm in diameter) curving fusion tubes to produce a fusion-tubegenerated membrane network (FTN). This network undergoes a serie ...
... details of cell-plate maturation have been revealed through the observation of cryofixed tobacco cells by Samuels et al. [5] (Figure 1a). Vesicles fuse via long thin (i.e. 20 nm in diameter) curving fusion tubes to produce a fusion-tubegenerated membrane network (FTN). This network undergoes a serie ...
Mitochondrial permeability transition pore as a target for - AJP
... At the end of the 20-min reoxygenation period, the cells were incubated in the dark for 10 min with annexin V-Fluos (AV, 20 M; Roche). Propidium iodide (PI, 3 nM; Sigma) was then added to the myocytes, and the samples were analyzed immediately with a fluorescent microscope. AV was shown previously ...
... At the end of the 20-min reoxygenation period, the cells were incubated in the dark for 10 min with annexin V-Fluos (AV, 20 M; Roche). Propidium iodide (PI, 3 nM; Sigma) was then added to the myocytes, and the samples were analyzed immediately with a fluorescent microscope. AV was shown previously ...
Draft De Novo Transcriptome of the Rat Kangaroo Potorous
... cells, these exogenous genes have come from other species, which can lead to experiment interpretation artifacts due to cross-species differences in sequence and function. Third, many antibodies developed against proteins from other species do not work in rat kangaroo. Fourth, modern genome- or tran ...
... cells, these exogenous genes have come from other species, which can lead to experiment interpretation artifacts due to cross-species differences in sequence and function. Third, many antibodies developed against proteins from other species do not work in rat kangaroo. Fourth, modern genome- or tran ...
Detection of Apoptosis in Paraffin Embedded Tissues: the Influence
... the Influence of Tissue Type and Fixation. Acta Vet Brno 2002, 71: 529-533. With increasing importance of apoptosis, many assays have been developed to detect apoptosis in cell populations and individual cells. Apoptotic cells are often proved using TUNEL assay based on detection of DNA strand break ...
... the Influence of Tissue Type and Fixation. Acta Vet Brno 2002, 71: 529-533. With increasing importance of apoptosis, many assays have been developed to detect apoptosis in cell populations and individual cells. Apoptotic cells are often proved using TUNEL assay based on detection of DNA strand break ...
Use of Recombinant Mucin Glycoprotein to Assess the
... altered transcription of genes encoding for mucin [4,5] or alteration in glycosylation of mucins [5,6]. Studies have also shown that bacterial gene expression can be altered upon exposure to mucin [7,8]. Despite its obvious importance our knowledge of how bacteria interact with mucins has lagged beh ...
... altered transcription of genes encoding for mucin [4,5] or alteration in glycosylation of mucins [5,6]. Studies have also shown that bacterial gene expression can be altered upon exposure to mucin [7,8]. Despite its obvious importance our knowledge of how bacteria interact with mucins has lagged beh ...
Heterodimerization and Endocytosis of Arabidopsis
... between the plasma membrane and the vesicle-like compartments was seen when compared with untreated protoplasts (data not shown) or to protoplasts expressing BRI1-YFP and AtSERK3-YFP overnight. In general, the expression was higher when the longer incubation time was used (cf. Figures 1I and 1K with ...
... between the plasma membrane and the vesicle-like compartments was seen when compared with untreated protoplasts (data not shown) or to protoplasts expressing BRI1-YFP and AtSERK3-YFP overnight. In general, the expression was higher when the longer incubation time was used (cf. Figures 1I and 1K with ...
The epithelial junction: bridge, gate, and fence.
... removed to a different cell, expecting to validate their procedure by observing no voltage step (because everyone then assumed the resistance between different epithelial cells to be infinite). Instead, they found to their astonishment that the voltage step was nearly as large as when both microelec ...
... removed to a different cell, expecting to validate their procedure by observing no voltage step (because everyone then assumed the resistance between different epithelial cells to be infinite). Instead, they found to their astonishment that the voltage step was nearly as large as when both microelec ...
The Immune System
... On the whole, your immune system does a remarkable job of defending you against disease-causing microorganisms. But sometimes it fails: A germ invades successfully and makes you sick. Is it possible to intervene in this process and make your immune system stronger? What if you improve your diet? Ta ...
... On the whole, your immune system does a remarkable job of defending you against disease-causing microorganisms. But sometimes it fails: A germ invades successfully and makes you sick. Is it possible to intervene in this process and make your immune system stronger? What if you improve your diet? Ta ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.