TEC-FAMILY KINASES: REGULATORS OF T-HELPER
... between their pleckstrin homology domains and the products of PI3K and/or other proteins. – second, phosphorylation by SRC-family kinases. – third, interactions with other proteins that bring the TEC-family kinases into antigen-receptor signaling complexes. – In addition, TEC-family kinases are thou ...
... between their pleckstrin homology domains and the products of PI3K and/or other proteins. – second, phosphorylation by SRC-family kinases. – third, interactions with other proteins that bring the TEC-family kinases into antigen-receptor signaling complexes. – In addition, TEC-family kinases are thou ...
Reproduction in Plants and animals
... reproduces by budding. Each cell forms a projection or bud and its nucleus divides into two by mitosis. One part of the nucleus moves into the bud which enlargens filling with cytoplasm and then can detach off the parent or remain attached to it to form a colony. Draw the diagram of yeast multiply ...
... reproduces by budding. Each cell forms a projection or bud and its nucleus divides into two by mitosis. One part of the nucleus moves into the bud which enlargens filling with cytoplasm and then can detach off the parent or remain attached to it to form a colony. Draw the diagram of yeast multiply ...
Cell Cycle Control - Georgia Institute of Technology
... E2F/DP1: S-phase transcription factor Retinoblastoma: E2F repressor p27/p21 KIP: cyclin kinase inhibitors p53: cell cycle withdrawal transcription ...
... E2F/DP1: S-phase transcription factor Retinoblastoma: E2F repressor p27/p21 KIP: cyclin kinase inhibitors p53: cell cycle withdrawal transcription ...
Daratumumab-mediated lysis of primary multiple
... Since the signals transmitted by inhibitory KIRs may prevent NK cell-mediated ADCC, even in the presence of an activating receptor-ligand interaction,12 we set out to test the possibility of improving DARA efficacy by blocking inhibitory KIRs. IPH2102 (formerly 1-7F9 and IPH2101) is a hinge-stabiliz ...
... Since the signals transmitted by inhibitory KIRs may prevent NK cell-mediated ADCC, even in the presence of an activating receptor-ligand interaction,12 we set out to test the possibility of improving DARA efficacy by blocking inhibitory KIRs. IPH2102 (formerly 1-7F9 and IPH2101) is a hinge-stabiliz ...
Cloning of the Complete Ly-6E.1 Gene and
... and suggests a difference in allelic regulatory sequences. It is not known whether these patterns of expression are the result of transcriptional or posttranscriptional control. and portions Previously, the complete Ly-6A.2 ofthe Ly-6E. 1 and Ly-6A.2 genes'' have been cloned. However, little is know ...
... and suggests a difference in allelic regulatory sequences. It is not known whether these patterns of expression are the result of transcriptional or posttranscriptional control. and portions Previously, the complete Ly-6A.2 ofthe Ly-6E. 1 and Ly-6A.2 genes'' have been cloned. However, little is know ...
Michael P. Kowalski1, Vipat Raksakulthai2
... cytometry. Maximal responses (blue boxes) correlate with imaging results for staurosporine and camptothecin but 5-fluorouracil treatment shows significant positive staining (>50% at maximal concentration). This suggests that 5-fluorouracil treated spheroids may be resistant to diffusion of the stain ...
... cytometry. Maximal responses (blue boxes) correlate with imaging results for staurosporine and camptothecin but 5-fluorouracil treatment shows significant positive staining (>50% at maximal concentration). This suggests that 5-fluorouracil treated spheroids may be resistant to diffusion of the stain ...
ESCV 2014 - Chromis Therapeutics
... Compound cytotoxicity was determined in parallel, using cells in same 96-well plates. The antiviral activity and cytotoxicity of the identified hits was further evaluated at multiple concentrations, and the EC50 and CC50 values were determined. As a result, at least five distinct chemistry series of ...
... Compound cytotoxicity was determined in parallel, using cells in same 96-well plates. The antiviral activity and cytotoxicity of the identified hits was further evaluated at multiple concentrations, and the EC50 and CC50 values were determined. As a result, at least five distinct chemistry series of ...
Investigating regulation of aging by transcription factors DAF 16 and
... • Longevity phenotypes noted: stress levels and movement • Microarray analysis: measure expression of each group • Cellular mRNA used to produce DNA ...
... • Longevity phenotypes noted: stress levels and movement • Microarray analysis: measure expression of each group • Cellular mRNA used to produce DNA ...
FROM THE LEAVES OF PHYLLOSTACHYS BAMBUSOIDES
... In order to evaluate the role of ethyl acetate fraction (PB-EtAC) obtained from the Phyllostachys bambusoides leaves in the modulation of immune responses, detailed studies were carried out using a panel of in vivo assays. Oral administration of PB-EtAC (50–200 mg/Kg) stimulated the IgM and IgG titr ...
... In order to evaluate the role of ethyl acetate fraction (PB-EtAC) obtained from the Phyllostachys bambusoides leaves in the modulation of immune responses, detailed studies were carried out using a panel of in vivo assays. Oral administration of PB-EtAC (50–200 mg/Kg) stimulated the IgM and IgG titr ...
Signalling in Plant Lateral Organ Development
... A plant lateral organ, defined here as either a leaf or a leaflike organ of the shoot or flower, arises from a group of initial cells within the flanks of the shoot apical meristem (SAM) or floral meristem. For example, the tobacco leaf is formed from a group of 100 initial cells in all three histo ...
... A plant lateral organ, defined here as either a leaf or a leaflike organ of the shoot or flower, arises from a group of initial cells within the flanks of the shoot apical meristem (SAM) or floral meristem. For example, the tobacco leaf is formed from a group of 100 initial cells in all three histo ...
FOREST BGENETICS LECTURE NOTE - The Federal University of
... mechanism for the transmission of hereditary xters, which are carried by the chromosomes. Meiosis actually involves two divisions. The first meiotic division (meiosis I) is a reductional division producing two haploid (n) cell from a single diploid (2n) cell. The second meiotic division (meiosis II) ...
... mechanism for the transmission of hereditary xters, which are carried by the chromosomes. Meiosis actually involves two divisions. The first meiotic division (meiosis I) is a reductional division producing two haploid (n) cell from a single diploid (2n) cell. The second meiotic division (meiosis II) ...
Differentiation of Cardiac Myocytes after Mitogen Withdrawal
... control their proliferative growth as well as the onset and establishment of a differentiated cardiac phenotype. However, the exact cellular and molecular mechanisms that regulate development in cardiac myocytes remain to be elucidated. Knowledge of the processes that regulate growth and differentia ...
... control their proliferative growth as well as the onset and establishment of a differentiated cardiac phenotype. However, the exact cellular and molecular mechanisms that regulate development in cardiac myocytes remain to be elucidated. Knowledge of the processes that regulate growth and differentia ...
HIF-2α phosphorylation by CK1δ promotes erythropoietin secretion
... Casein kinase 1δ supports HIF-2 transcriptional activity and stimulates EPO secretion To investigate the involvement of CK1δ in the regulation of HIF-2α, its expression was suppressed in Huh7 cells by small interfering RNA (siRNA)-mediated silencing. Treatment of cells with CK1δ siRNA under hypoxic ...
... Casein kinase 1δ supports HIF-2 transcriptional activity and stimulates EPO secretion To investigate the involvement of CK1δ in the regulation of HIF-2α, its expression was suppressed in Huh7 cells by small interfering RNA (siRNA)-mediated silencing. Treatment of cells with CK1δ siRNA under hypoxic ...
Lipid defense response of Chlorella as theoretical background in
... In the study described here, Chlorella began to collect starch as usual after co-immobilization with bacteria, but all carbon pathway changed, so the algae lost their characteristic one-cellular stage and after several divisions both onecellular and multicellular stages were observed (Figs. 1a-1d). ...
... In the study described here, Chlorella began to collect starch as usual after co-immobilization with bacteria, but all carbon pathway changed, so the algae lost their characteristic one-cellular stage and after several divisions both onecellular and multicellular stages were observed (Figs. 1a-1d). ...
Passive and Active Transport
... THE CELL MEMBRANE: DIFFUSION • What factors determine whether diffusion occurs across a membrane? • Is there equilibrium between the inside & outside of the cell membrane? • If the answer is no then diffusion will occur. • How permeable is the membrane? • selectively permeable – description of a bio ...
... THE CELL MEMBRANE: DIFFUSION • What factors determine whether diffusion occurs across a membrane? • Is there equilibrium between the inside & outside of the cell membrane? • If the answer is no then diffusion will occur. • How permeable is the membrane? • selectively permeable – description of a bio ...
an eGOcentric view of tOrC1 signaling
... enriched in brain) that directly interacts with and positively regulates mTORC1 in its GTP-bound state.3 Interestingly, TSC2, but not Rheb, appears to be dispensable for coupling amino acid signals to mTORC1, suggesting the existence of additional proteins that participate in amino acid regulation o ...
... enriched in brain) that directly interacts with and positively regulates mTORC1 in its GTP-bound state.3 Interestingly, TSC2, but not Rheb, appears to be dispensable for coupling amino acid signals to mTORC1, suggesting the existence of additional proteins that participate in amino acid regulation o ...
Immunology
... MHC is a genetic region found in all mammals though details of the complex vary from one species to the next. In human the locus is known as HLA, in mice it's known as H2-Locus. MHC (HLA): Definition: It is a group of tissue antigens, controlled by chromosomal region, bearing a no. of genetic loci, ...
... MHC is a genetic region found in all mammals though details of the complex vary from one species to the next. In human the locus is known as HLA, in mice it's known as H2-Locus. MHC (HLA): Definition: It is a group of tissue antigens, controlled by chromosomal region, bearing a no. of genetic loci, ...
Stochasticity in the symmetric division of plant cells: when the
... of control. In that respect, a notable consequence of the stochastic division rule expounded above can be deduced directly from the exponential law that governs it (Figure 1G). While isodiametric cells (small δij values) exert poor control over the selection of their division plane, highly elongated ...
... of control. In that respect, a notable consequence of the stochastic division rule expounded above can be deduced directly from the exponential law that governs it (Figure 1G). While isodiametric cells (small δij values) exert poor control over the selection of their division plane, highly elongated ...
The role of Cdc14 phosphatases in the control of cell division
... A role for Cdc14 in cytokinesis is likely to be general but its influence on this process varies between organisms. In Caenorhabditis elegans embryogenesis, for example, a role for Cdc14 in cytokinesis was only revealed in animals producing a tagged allele of a central spindle component, Zen-4, that ...
... A role for Cdc14 in cytokinesis is likely to be general but its influence on this process varies between organisms. In Caenorhabditis elegans embryogenesis, for example, a role for Cdc14 in cytokinesis was only revealed in animals producing a tagged allele of a central spindle component, Zen-4, that ...
Cellular Structure and Function
... all organisms are made of one or more cells, all the life functions of organisms occur within cells, and all cells come from already existing cells. • All cells are very small because they need to pass substances across their surface. Their small size gives them a relatively large ratio of surface a ...
... all organisms are made of one or more cells, all the life functions of organisms occur within cells, and all cells come from already existing cells. • All cells are very small because they need to pass substances across their surface. Their small size gives them a relatively large ratio of surface a ...
Glucosamine induces cell-cycle arrest and hypertrophy of mesangial
... [25]. To this end, mesangial cells were treated with either 0.5 or 5 mM GlcN, collected and the cell number and total protein content were measured. As shown in Figure 1, time-course experiments revealed that GlcN potently decreases proliferation. The effect of GlcN was evident starting from 48 h an ...
... [25]. To this end, mesangial cells were treated with either 0.5 or 5 mM GlcN, collected and the cell number and total protein content were measured. As shown in Figure 1, time-course experiments revealed that GlcN potently decreases proliferation. The effect of GlcN was evident starting from 48 h an ...
expression and function of receptors for leptin and ghrelin in sh
... producing the potent orexigenic peptide neuropeptide Y (NPY). In the rat, leptin, acting via OBRb, the long leptin receptor isoform, has been shown to induce satiety in parallel with a marked reduction of the hypothalamic expression of NPY. Ghrelin, a hunger hormone predominantly produced by the sto ...
... producing the potent orexigenic peptide neuropeptide Y (NPY). In the rat, leptin, acting via OBRb, the long leptin receptor isoform, has been shown to induce satiety in parallel with a marked reduction of the hypothalamic expression of NPY. Ghrelin, a hunger hormone predominantly produced by the sto ...
nutrient uptake and assimilation
... • Nutrient ions must be dissolved in soil water (“soil solution”) for uptake by plants • They move from “soil solution” to vascular center of plant root passing through at least one cell membrane (the “skin” that hold the cell’s liquid contents inside) • This movement, across the membrane, may be pa ...
... • Nutrient ions must be dissolved in soil water (“soil solution”) for uptake by plants • They move from “soil solution” to vascular center of plant root passing through at least one cell membrane (the “skin” that hold the cell’s liquid contents inside) • This movement, across the membrane, may be pa ...
Sensing minute changes in biological cell monolayers with THz
... doi:10.1016/j.bios.2006.02.021 ...
... doi:10.1016/j.bios.2006.02.021 ...
Cellular differentiation
In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.