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Selecting B cells and plasma cells to memory
Selecting B cells and plasma cells to memory

... determined by their affinity for the respective antigen and their survival potency, which is determined by the expression of genes that mediate survival signals and prevent apoptosis (Fig. 1). Inside and outside of “niches” providing the essential survival signals, the phenotype of such B cells may ...
An Immortalized Myocyte Cell Line, HL-1, Expresses a Functional
An Immortalized Myocyte Cell Line, HL-1, Expresses a Functional

... [3H]bremazocine binding. This is contrary to previous findings that this ligand does bind to cardiac membranes.7,8,22 The difference may be attributable to species differences (rat v mouse) or indeed may be due to the fact that we are using an immortalized myocyte cell line. In addition, the standar ...
Plant hormones and phototropism
Plant hormones and phototropism

... Auxin is transported unidirectionally when a shoot is exposed to light from one direction only. Along this pathway, the hormone enters a cell at the lighted end, exits at the shaded end, diffuses across the wall, and enters the next cell. A pH difference between the cell wall (acidic at about pH 5) ...
3 Chapter 3
3 Chapter 3

... 3.2 Opening Questions: What are you really made of? • Did you know that scientists estimate that only maybe one in 10 of the cells in your body are actually human! The rest are largely prokaryote cells. These good bacteria help us digest food, synthesize ...
IL-10 transcription is negatively regulated by BAF180, a component
IL-10 transcription is negatively regulated by BAF180, a component

... the hydrolysis of ATP to changes in chromatin structure. SWI/SNF, Mi2, ISWI, and other ATP-dependent remodeling enzymes are classified into subfamilies based upon homology of the ATPase subunit [4,19,20]. These remodeling enzymes appear to both activate and repress gene expression [4,21-25]. SWI/SNF ...
The Organization Pattern of Root Border
The Organization Pattern of Root Border

... attached to each other rather than completely detached from each other, as is usually observed in border cells of many species. Unlike border cells, cell attachment between border-like cells is maintained after their release into the external environment. To investigate the role of cell wall polysac ...
Replication and morphogenesis of Amsacta moorei entomopoxvirus
Replication and morphogenesis of Amsacta moorei entomopoxvirus

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- University of East Anglia
- University of East Anglia

... Hamilton (HH) stage 3 (Garcia-Martinez and Schoenwolf, 1993; Hamburger and Hamilton, 1951; Rosenquist, 1970). In the chick, a simple, contractile heart tube forms by HH stage 10, which is after approximately 48 hours of development. The specification of prospective cardiac cells occurs concomitantly ...
Early Development of Vertebrates
Early Development of Vertebrates

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PDF
PDF

... outgrowths after fixation and staining indicated that results based on the two methods do not differ significantly (7 = 1-56, d.f. = 20, P > 0-10). Consequently, nuclear counts were performed by phase-contrast microscopy at 12 h intervals on each individual explant. Giant-cell nuclei were recognized ...
Exosome-Depleted FBS Using Beckman Coulter Centrifugation:
Exosome-Depleted FBS Using Beckman Coulter Centrifugation:

... of the process. In this process, large volumes of FBS can easily be centrifuged at high speeds to eliminate native extracellular vesicles typically in an overnight spin. However, there are also commercially available products which have pre-conditioned the media to be depleted of exosomes and other ...
cell behaviour during active cell rearrangement: evidence and
cell behaviour during active cell rearrangement: evidence and

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Transport across membrane 3 - E-Learning/An
Transport across membrane 3 - E-Learning/An

... function through conformational change = shape change ...
AP Biology Chapter 20 Biotechnology Guided Notes
AP Biology Chapter 20 Biotechnology Guided Notes

... Gel Electrophoresis and Southern Blotting • One indirect method of rapidly analyzing and comparing genomes is ___________________ • This technique uses a gel as a _______________ to separate nucleic acids or proteins by ______ ___________________, and other properties • A ________________ is applie ...
The Cell Membrane
The Cell Membrane

... function through conformational change = shape change ...
MAKEUP: Thyroid Hormone Synthesis
MAKEUP: Thyroid Hormone Synthesis

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Signal Transduction by the Receptors for Thrombopoietin (c
Signal Transduction by the Receptors for Thrombopoietin (c

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PDF

... treated 18-day-old tooth germs. Furthermore, in explants in which the cuspal odontoblasts had been allowed to differentiate over 2 days of culture prior to DON addition, differentiation proceeded only in the cuspal area, and the boundary with the undifferentiated more cervical area was clear-cut. In ...
Mutants of the Membrane-binding Region of Semliki Forest Virus E2
Mutants of the Membrane-binding Region of Semliki Forest Virus E2

... To construct pSFd, the origin of replication of the phage FI was isolated from pD4 (l l) as an EcoRl fragment, and the ends were filled in and then ligated into pS-S-SFV at the PvulI site. One of the two EcoRl sites was recreated (see Fig. 2 a). Wild-type pS-S-SFV has been described elsewhere (27). ...
II. EFFECTS OF ANTI-Ia SERA ON MITOGENIC RESPONSES
II. EFFECTS OF ANTI-Ia SERA ON MITOGENIC RESPONSES

... It was previously reported t h a t pretreatment of splenic lymphoid cells with anti-Ia serum without complement inhibited the in vitro humoral response to heterologous erythrocytes and the proliferative response to LPS (15, 16). Similar pretreatment of spleen cells with anti-Ia serum without complem ...
An lmmunohistochemical and Quantitative Examination of Dorsal
An lmmunohistochemical and Quantitative Examination of Dorsal

... sizing. Figure 2 shows the size distribution of the total neuronal population of L6 DRG. It has a roughly bimodal form, and it is known from the work of a number of previous workers (see Lawson, 1979) that there is a small cell population with a size range from about 15 to 35 pm in diameter and with ...
Cell Communication Chapter 11
Cell Communication Chapter 11

... Response: Cell signaling leads to regulation of transcription or cytoplasmic activities •The cell’s response to an extracellular signal is sometimes called the “output response” ...
A Comprehensive Gene Expression Analysis Toward the
A Comprehensive Gene Expression Analysis Toward the

... 2003). However, the mechanism of cytokinesis in plants differs completely from that of both animals and fungi (Criqui and Genschik 2002). Thus, many genes involved in plant cytokinesis cannot be predicted from the comparison of genomic data of plants and other organisms. To date, several plant-speci ...
Membrane trafficking in Drosophila wing and eye development
Membrane trafficking in Drosophila wing and eye development

... The adult Drosophila eye consists of an array of approximately 800 ommatidial units. Each ommatidium contains eight photoreceptor cells and four cone cells and a number of support cells. The photoreceptors are arranged in a trapezoidal array with their apical surfaces facing the interior of the stru ...
Actin in plants
Actin in plants

... narrows as in-furrowing proceeds - clearly inviting comparison with the contractile ring of animal cytokinesis. No specific mention is made of how the ring of actin relates to the central algal phragmoplast. However, since F-actin is reportedly present in a ring "until the cell is finally divided in ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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