Xp11 translocation RCC
... kinase receptor that drives oncogenesis MET inhibitors now in clinical trial for patients with advanced carcinoma Other targeted therapy: VEGF or mTOR inhibitors ...
... kinase receptor that drives oncogenesis MET inhibitors now in clinical trial for patients with advanced carcinoma Other targeted therapy: VEGF or mTOR inhibitors ...
Review Article Oncogene: The Dominant Evil
... oxygen species (ROS). These ROS have roles in mediating cell proliferation, genomic instability, cell motility and angiogenesis and thus can contribute to tumorigenesis, but also can induce cell cycle arrest, senescence and cell death and thus attenuate tumor growth14 ...
... oxygen species (ROS). These ROS have roles in mediating cell proliferation, genomic instability, cell motility and angiogenesis and thus can contribute to tumorigenesis, but also can induce cell cycle arrest, senescence and cell death and thus attenuate tumor growth14 ...
Identification and localization of a β‐COP‐like protein involved in the
... showed that b-COP-like proteins marked predominantly the plant Golgi apparatus. Other proteins known to be part of a potential machinery for COPI vesicle formation (g-COP, b¢-COP and Arf1 proteins) were immunolocalized on the same membraneous structures as b-COP. Moreover, b-COP and other COPI antib ...
... showed that b-COP-like proteins marked predominantly the plant Golgi apparatus. Other proteins known to be part of a potential machinery for COPI vesicle formation (g-COP, b¢-COP and Arf1 proteins) were immunolocalized on the same membraneous structures as b-COP. Moreover, b-COP and other COPI antib ...
Ordinal Position of Neurons in Cat Striate Cortex
... first-, second-, and third-order neurons. From the positions of these peaks one could deduce characteristic values of latencies for different ordinal positions and use these values to assign an ordinal position to each cell in the striate cortex. However, as shown in Fig. 2A, the histogram of latenc ...
... first-, second-, and third-order neurons. From the positions of these peaks one could deduce characteristic values of latencies for different ordinal positions and use these values to assign an ordinal position to each cell in the striate cortex. However, as shown in Fig. 2A, the histogram of latenc ...
Epidermal Pavement Cells of Arabidopsis Have
... Figure 1. Representative images illustrating the presence of small chloroplasts in epidermal pavement cells of Arabidopsis thaliana. A, Lateral view of the upper epidermal surface of a soil grown Arabidopsis plant expressing tpFNR:GFP shows the clear fluorescence of chlorophyll (red; panel 1) and t ...
... Figure 1. Representative images illustrating the presence of small chloroplasts in epidermal pavement cells of Arabidopsis thaliana. A, Lateral view of the upper epidermal surface of a soil grown Arabidopsis plant expressing tpFNR:GFP shows the clear fluorescence of chlorophyll (red; panel 1) and t ...
Xylem and Phloem Comparison Chart
... Forms vascular bundles with phloem and gives mechanical strength to plant due to presence of lignin cells. The lignified secondary wall also makes the xylem waterproof and prevent it from collapsing under the pressure of water transpiration occurring in the leaves. ...
... Forms vascular bundles with phloem and gives mechanical strength to plant due to presence of lignin cells. The lignified secondary wall also makes the xylem waterproof and prevent it from collapsing under the pressure of water transpiration occurring in the leaves. ...
Great Expectations for PIP: Phosphoinositides as Regulators of
... Phosphoinositides function as signaling precursors as well as regulators and scaffolds of signaling molecules required for important cellular processes such as membrane trafficking. Although a picture of the biochemical and cell biological functions of phosphoinositides is emerging, less is known ab ...
... Phosphoinositides function as signaling precursors as well as regulators and scaffolds of signaling molecules required for important cellular processes such as membrane trafficking. Although a picture of the biochemical and cell biological functions of phosphoinositides is emerging, less is known ab ...
Document
... With respect to the above question, Dyneins move material towards which end of the filament? (a) ...
... With respect to the above question, Dyneins move material towards which end of the filament? (a) ...
Clinical Genomic Analysis and Diagnosis -
... microarray by total mRNA, array CGH by total genome DNA and proteomics by total protein, genomic analysis in silico is an exclusive way for the analysis of genomic data because the genomic data at the tissue level are mixed with genome fro m different cells[24]. According to our experiences, at leas ...
... microarray by total mRNA, array CGH by total genome DNA and proteomics by total protein, genomic analysis in silico is an exclusive way for the analysis of genomic data because the genomic data at the tissue level are mixed with genome fro m different cells[24]. According to our experiences, at leas ...
Galluzzi et al., 2007. Cell Death and Differentition 14:1237-1266
... have not yet been solved. In this review, we will synthetically and critically enumerate the current classifications of cell death, laying special emphasis on the link between the morphological, biochemical and pathophysiological characteristics of different cell death modalities. Morphological Char ...
... have not yet been solved. In this review, we will synthetically and critically enumerate the current classifications of cell death, laying special emphasis on the link between the morphological, biochemical and pathophysiological characteristics of different cell death modalities. Morphological Char ...
Programmed Changes in Form during Moss Development
... Further evidence that calcium plays an important role in initial cell formation comes from studies measuring currents along a caulonema filament with a nonintrusive vibrating microelectrode (Saunders, 1986). In a caulonema cell, maximal inward current was measured near the nucleus (midway along the ...
... Further evidence that calcium plays an important role in initial cell formation comes from studies measuring currents along a caulonema filament with a nonintrusive vibrating microelectrode (Saunders, 1986). In a caulonema cell, maximal inward current was measured near the nucleus (midway along the ...
Munc18b is an essential gene in mice whose expression is limiting
... cloned between the ClaI and KpnI sites. This targeting vector was electroporated into B6129SF1 ES cells that were then subjected to positive selection of recombination events with neomycin and to negative selection of non-homologous recombination events with gancyclovir. ES cell clones were assessed ...
... cloned between the ClaI and KpnI sites. This targeting vector was electroporated into B6129SF1 ES cells that were then subjected to positive selection of recombination events with neomycin and to negative selection of non-homologous recombination events with gancyclovir. ES cell clones were assessed ...
Role of Membrane Potential in the Regulation of Cell Proliferation
... Stem Cell Rev and Rep (2009) 5:231–246 ...
... Stem Cell Rev and Rep (2009) 5:231–246 ...
Synaptic basis for intense thalamocortical activation of feedforward
... cells that receive direct thalamocortical excitation6–11. Although the consequences of feedforward inhibition have been extensively considered12–14, little is known about the mechanisms of the strong interneuron activation that produces it. Obviously, understanding how both inhibitory and excitatory ...
... cells that receive direct thalamocortical excitation6–11. Although the consequences of feedforward inhibition have been extensively considered12–14, little is known about the mechanisms of the strong interneuron activation that produces it. Obviously, understanding how both inhibitory and excitatory ...
Intracellular adhesion molecule-1 modulates β-chemokines
... that play a major role in a variety of immune and inflammatory responses, acting primarily as chemoattractants and activators of various leukocytes (1–3). To carry out these functions, chemokines regulate a variety of molecules. Among the important molecules regulated by chemokine expression are adh ...
... that play a major role in a variety of immune and inflammatory responses, acting primarily as chemoattractants and activators of various leukocytes (1–3). To carry out these functions, chemokines regulate a variety of molecules. Among the important molecules regulated by chemokine expression are adh ...
Teratocarcinoma stem cells as a model for differentiation inthe
... differentiation of cells can influence their adherence. For example, erythroid differentiation of erythroleukemia cells leads to a reduced adherence to fibronectin (Patel and lodish, 1984). Changes in the capacity to adhere to specific matrix components accompany F9 cell differentiation as well (Tie ...
... differentiation of cells can influence their adherence. For example, erythroid differentiation of erythroleukemia cells leads to a reduced adherence to fibronectin (Patel and lodish, 1984). Changes in the capacity to adhere to specific matrix components accompany F9 cell differentiation as well (Tie ...
word - My eCoach
... The cell cycle includes all of the phasesin the life of a cell. The cell cycle is a repeating sequenceof cellular growth and division during the life of an organism. Mitosis is one of the phasesin the cell cycle. Mitosis is the process by which the material in a cell's nucleus is divided during cell ...
... The cell cycle includes all of the phasesin the life of a cell. The cell cycle is a repeating sequenceof cellular growth and division during the life of an organism. Mitosis is one of the phasesin the cell cycle. Mitosis is the process by which the material in a cell's nucleus is divided during cell ...
The phosphatidylinositol transfer protein RdgBβ binds 14-3
... kidney, liver, peripheral blood leucocytes, brain and testes [16,17]. However, the presence of the endogenous protein has mainly been described from high-throughput proteomic screens [18–22]. The PITP domain of human RdgBβ is 41 % identical with PITPα and retains all of the key residues that are ess ...
... kidney, liver, peripheral blood leucocytes, brain and testes [16,17]. However, the presence of the endogenous protein has mainly been described from high-throughput proteomic screens [18–22]. The PITP domain of human RdgBβ is 41 % identical with PITPα and retains all of the key residues that are ess ...
Membrane traffic in cytokinesis - Biochemical Society Transactions
... at a later stage of cytokinesis in mammalian cells. For example, dynamin, which is a key endocytic protein, has been shown to localize to the central spindle and later to the mid-body in both C. elegans and mammalian cells. In addition, depletion of dynamin in C. elegans has been shown to cause both ...
... at a later stage of cytokinesis in mammalian cells. For example, dynamin, which is a key endocytic protein, has been shown to localize to the central spindle and later to the mid-body in both C. elegans and mammalian cells. In addition, depletion of dynamin in C. elegans has been shown to cause both ...
Le Van Kim and Wassim El Nemer Grandis, Yves - Labex GR-Ex
... the activation of the protein kinase A (PKA) signaling pathway (5, 12, 13). Whereas LW/ICAM-4 is an erythroid-specific protein, Lu/BCAM exhibits a broad expression pattern (14, 15). Lu/BCAM is expressed on resting endothelial cells where it contributes to abnormal SS reticulocyte adhesion by interac ...
... the activation of the protein kinase A (PKA) signaling pathway (5, 12, 13). Whereas LW/ICAM-4 is an erythroid-specific protein, Lu/BCAM exhibits a broad expression pattern (14, 15). Lu/BCAM is expressed on resting endothelial cells where it contributes to abnormal SS reticulocyte adhesion by interac ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).