Stem cell technology for drug discovery and development
... In addition to using stem cells and their derivatives for more traditional drug screening they also have potential for discovering novel drugs or factors to promote endogenous cells to repopulate lost or diseased cells in conditions such as stroke. Regenerative drugs are already available, such as e ...
... In addition to using stem cells and their derivatives for more traditional drug screening they also have potential for discovering novel drugs or factors to promote endogenous cells to repopulate lost or diseased cells in conditions such as stroke. Regenerative drugs are already available, such as e ...
REGULATION OF ACID
... therefore, more CO2 and H2O are formed 7. CO2 stimulates respiration and CO2 is eliminated from the extracellular fluid 8. When a strong base (ex. NaOH) is added to the bicarbonate buffer solution the hydroxyl ion (OH-) from the NaOH combines with H2CO3 to form HCO3-. The weak base NaHCO3 replaces ...
... therefore, more CO2 and H2O are formed 7. CO2 stimulates respiration and CO2 is eliminated from the extracellular fluid 8. When a strong base (ex. NaOH) is added to the bicarbonate buffer solution the hydroxyl ion (OH-) from the NaOH combines with H2CO3 to form HCO3-. The weak base NaHCO3 replaces ...
SCD1 is required for cell cytokinesis and polarized
... fusion. KNOLLE encodes a homolog of syntaxin, a mammalian plasma membrane SNARE (soluble N-ethylmaleimidesensitive fusion attachment protein receptors) required for the fusion of exocytic vesicles, whereas KEULE encodes a homolog of yeast Sec1p that regulates syntaxin function. These factors have be ...
... fusion. KNOLLE encodes a homolog of syntaxin, a mammalian plasma membrane SNARE (soluble N-ethylmaleimidesensitive fusion attachment protein receptors) required for the fusion of exocytic vesicles, whereas KEULE encodes a homolog of yeast Sec1p that regulates syntaxin function. These factors have be ...
Membranes - Active Transport (GPC)
... transporters can also transport small, uncharged organic molecules like glucose. These three types of carrier proteins are also found in facilitated diusion,+but+they do not require ATP to work in that process. Some examples of pumps for active transport are Na -K ATPase, which carries sodium and p ...
... transporters can also transport small, uncharged organic molecules like glucose. These three types of carrier proteins are also found in facilitated diusion,+but+they do not require ATP to work in that process. Some examples of pumps for active transport are Na -K ATPase, which carries sodium and p ...
PPT1 - Ycmou
... Our body limbs move because of contraction and relaxation of skeleton muscles. But do you know that cell also possess some kind of muscles to its various activities such as transport of cellular organelles in the cytoplasm, for cell division, for its own movement? Yes cells possess the kind of muscl ...
... Our body limbs move because of contraction and relaxation of skeleton muscles. But do you know that cell also possess some kind of muscles to its various activities such as transport of cellular organelles in the cytoplasm, for cell division, for its own movement? Yes cells possess the kind of muscl ...
Reviews
... of the most important biological properties of HA, introducing its interactions with proteins, cells, and tissue. Then, since the molecular structure of HA is at the basis of its properties, a paragraph will address present information on HA molecular behavior in aqueous solutions, trying to identif ...
... of the most important biological properties of HA, introducing its interactions with proteins, cells, and tissue. Then, since the molecular structure of HA is at the basis of its properties, a paragraph will address present information on HA molecular behavior in aqueous solutions, trying to identif ...
Cell Injury
... Generation of ROS • Oxidation - reduction reactions • Absorption of radiant energy • Rapid bursts of ROS produced in activated leukocytes during inflammation • Enzymatic metabolism of exogenous chemicals or drugs • Transition metals - iron and copper ...
... Generation of ROS • Oxidation - reduction reactions • Absorption of radiant energy • Rapid bursts of ROS produced in activated leukocytes during inflammation • Enzymatic metabolism of exogenous chemicals or drugs • Transition metals - iron and copper ...
Gastrointestinal MALT Lymphoma
... “marginal zones” of neoplastic cells (analogous to Peyer’s patches) • Neoplastic cells infiltrate mucosa widely, creating LELs • Defined as at least three neoplastic cells, causing epithelial ...
... “marginal zones” of neoplastic cells (analogous to Peyer’s patches) • Neoplastic cells infiltrate mucosa widely, creating LELs • Defined as at least three neoplastic cells, causing epithelial ...
Weber et al_rev Legends of supplementary figures and tables
... levels, expressed relative to EF1, were determined by quantitative real-time PCR for seedlings grown in liquid culture to comparable size (7-9d). Data represent means of three independent experiments. (b) Seedlings of Col-0 as well as homozygous transgenic PME3-Col-OX and PME3-mut-OX lines were gro ...
... levels, expressed relative to EF1, were determined by quantitative real-time PCR for seedlings grown in liquid culture to comparable size (7-9d). Data represent means of three independent experiments. (b) Seedlings of Col-0 as well as homozygous transgenic PME3-Col-OX and PME3-mut-OX lines were gro ...
Melanotransferrin stimulates t-PA
... In light of the importance of sMTf and plasminogen interaction [6,42], we investigated the potential effects of sMTf on the EC plasminogen activation system. Media from cells treated with different combinations of plasminogen, t-PA and sMTf were subjected to Western blot analysis. The activation of ...
... In light of the importance of sMTf and plasminogen interaction [6,42], we investigated the potential effects of sMTf on the EC plasminogen activation system. Media from cells treated with different combinations of plasminogen, t-PA and sMTf were subjected to Western blot analysis. The activation of ...
characterization of adult and embryonic stem cell proliferation
... stem cell is. A variety of definitions have been proposed, but a common set of terms and properties emerged that serves as a starting point. By focusing on embryonic stem cells and neural stem cells we compared and contrast the two most common “types” of stem cells: embryonic and adult stem cells. T ...
... stem cell is. A variety of definitions have been proposed, but a common set of terms and properties emerged that serves as a starting point. By focusing on embryonic stem cells and neural stem cells we compared and contrast the two most common “types” of stem cells: embryonic and adult stem cells. T ...
Deflagellation and Flagellar Regeneration in Chlamydomonas
... locomotion. The flagellar axoneme is comprised of a 9+2 arrangement of microtubules. The microtubules are always observed in a characteristic array of 9 outer doublet microtubules surrounding a central pair of two single microtubules. This 9+2 arrangement is highly conserved. You will be able to ide ...
... locomotion. The flagellar axoneme is comprised of a 9+2 arrangement of microtubules. The microtubules are always observed in a characteristic array of 9 outer doublet microtubules surrounding a central pair of two single microtubules. This 9+2 arrangement is highly conserved. You will be able to ide ...
Skeletal Muscle Tissue and Fiber Types
... Skeletal Muscle Tissue and Fiber Types Muscle contractions are among the largest energy-consuming processes in the body, which is not surprising considering the work that muscles constantly do. Skeletal muscles move the body in obvious ways such as walking and in less noticeable ways such as facilit ...
... Skeletal Muscle Tissue and Fiber Types Muscle contractions are among the largest energy-consuming processes in the body, which is not surprising considering the work that muscles constantly do. Skeletal muscles move the body in obvious ways such as walking and in less noticeable ways such as facilit ...
Kerr et al 2016_04_08 - OPUS at UTS
... HeLa cells stably expressing mCherry-Rab25 were seeded onto imaging plates, transfected with soluble GFP and infected with CTL2 for 48h p.i. The cells were imaged live on a line scanning confocal microscope for 3 frames before a 0.6μm3 region of the inclusion was ablated (reticule) and the samples i ...
... HeLa cells stably expressing mCherry-Rab25 were seeded onto imaging plates, transfected with soluble GFP and infected with CTL2 for 48h p.i. The cells were imaged live on a line scanning confocal microscope for 3 frames before a 0.6μm3 region of the inclusion was ablated (reticule) and the samples i ...
Cancer stem cells - normal stem cells "Jedi" that went over to the
... origin of lung adenocarcinomas [18] and Sca-1+ CD45cells to be the origin of prostate cancer [5, 49]. Furthermore, recent evidence accumulated that an α-chemokine receptor CXCR4 that is expressed on embryonic stem cells [25] as well as normal TCSC/PSC for different organs/tissues [1, 2, 14, 19, 37, ...
... origin of lung adenocarcinomas [18] and Sca-1+ CD45cells to be the origin of prostate cancer [5, 49]. Furthermore, recent evidence accumulated that an α-chemokine receptor CXCR4 that is expressed on embryonic stem cells [25] as well as normal TCSC/PSC for different organs/tissues [1, 2, 14, 19, 37, ...
Chapter 3 PowerPoint
... Several organelles are involved in making and processing proteins. (continued) • Ribosomes link amino acids to form proteins. • Golgi Apparatus- process, sort & deliver proteins • Vesicles are membrane-bound sacs that hold materials until it is ready for use. ...
... Several organelles are involved in making and processing proteins. (continued) • Ribosomes link amino acids to form proteins. • Golgi Apparatus- process, sort & deliver proteins • Vesicles are membrane-bound sacs that hold materials until it is ready for use. ...
6.cellandnucleardivision
... • A hypothetical sequence for the evolution of mitosis (a) Prokaryotes. During binary fission, the origins of the daughter chromosomes move to opposite ends of the cell. The mechanism is not fully understood, but proteins may anchor the daughter chromosomes to specific sites on the plasma membrane. ...
... • A hypothetical sequence for the evolution of mitosis (a) Prokaryotes. During binary fission, the origins of the daughter chromosomes move to opposite ends of the cell. The mechanism is not fully understood, but proteins may anchor the daughter chromosomes to specific sites on the plasma membrane. ...
Slide 1
... 37°C or 30°C, to produce hyphae or yeast cells, respectively. Cultures were incubated for 7 days at 37°C or 30°C after addition of 2.5mL of a midlog culture of bacterial cells (P. aeruginosa, P. mirabilis, K. oxytoca, or M. luteus). Hypoxic conditions were created by withholding oxygen from cultures ...
... 37°C or 30°C, to produce hyphae or yeast cells, respectively. Cultures were incubated for 7 days at 37°C or 30°C after addition of 2.5mL of a midlog culture of bacterial cells (P. aeruginosa, P. mirabilis, K. oxytoca, or M. luteus). Hypoxic conditions were created by withholding oxygen from cultures ...
The expression of transforming growth factor-βs and TGF
... with maximal effect occurring at 5 ng/ml (P ,0.05). TGFβ1–3 at all the concentrations tested had no significant effect on cell proliferation determined by cell counting (data not shown) compared with 2% FBS. Specific neutralizing antibodies to TGF-β1 (10 µg/ml), TGF-β2 (10 µg/ml) or TGF-β3 (6 to 10 ...
... with maximal effect occurring at 5 ng/ml (P ,0.05). TGFβ1–3 at all the concentrations tested had no significant effect on cell proliferation determined by cell counting (data not shown) compared with 2% FBS. Specific neutralizing antibodies to TGF-β1 (10 µg/ml), TGF-β2 (10 µg/ml) or TGF-β3 (6 to 10 ...
A Model-Based Approach for Automated In Vitro Cell - LISA
... treated sequences (i.e., ensuring robustness, data not shown). It is interesting to point out that an optimized code enabled an image to be preprocessed in less than 3 s on a standard 1.4 MHz Pentium IV computer. Cell marking. A human operator is asked to manually select the cells to be tracked on t ...
... treated sequences (i.e., ensuring robustness, data not shown). It is interesting to point out that an optimized code enabled an image to be preprocessed in less than 3 s on a standard 1.4 MHz Pentium IV computer. Cell marking. A human operator is asked to manually select the cells to be tracked on t ...
Subcellular localization of yeast CDC46 varies with the cell cycle.
... very early in the cell cycle, prior to or early in DNA synthesis. We have determined whether a cdc46 mutation will prevent cells from completing the cell cycle after a block in DNA elongation is removed, as would be expected for a block in DNA initiation (Hartwell 1976). If the CDC46 gene product ca ...
... very early in the cell cycle, prior to or early in DNA synthesis. We have determined whether a cdc46 mutation will prevent cells from completing the cell cycle after a block in DNA elongation is removed, as would be expected for a block in DNA initiation (Hartwell 1976). If the CDC46 gene product ca ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).