Chapter 2.3 Active Cell Processes: Motility, Muscle, and Mechanotransduction
... chemotactic agents. Other cells may have different reasons for migration. Migration is an essential element in growth and development, but also plays a critical role in the metastatic spread of cancer cells. Fibroblasts, normally sedentary factories of extracellular matrix components, become motile ...
... chemotactic agents. Other cells may have different reasons for migration. Migration is an essential element in growth and development, but also plays a critical role in the metastatic spread of cancer cells. Fibroblasts, normally sedentary factories of extracellular matrix components, become motile ...
Retinoic acid receptor alpha drives cell cycle progression and is
... therapeutic targets in PTCL is critical to improving outcomes in this disease. Retinoic acid receptor alpha (RARA) is a transcription factor that forms heterodimers with retinoid X receptor (RXR) [4]. These heterodimers bind to DNA motifs known as retinoic acid response elements (RAREs) and regulate ...
... therapeutic targets in PTCL is critical to improving outcomes in this disease. Retinoic acid receptor alpha (RARA) is a transcription factor that forms heterodimers with retinoid X receptor (RXR) [4]. These heterodimers bind to DNA motifs known as retinoic acid response elements (RAREs) and regulate ...
Chapter 1 - Richsingiser.com
... • The processes of life have durations ranging over 33 orders of magnitude • From 10-15 sec (for electron transfer reactions) • To 1018 sec (the period of evolution, from the first appearance of organisms to today) • The processes and lifetimes described in Table 1.5 will be discussed throughout the ...
... • The processes of life have durations ranging over 33 orders of magnitude • From 10-15 sec (for electron transfer reactions) • To 1018 sec (the period of evolution, from the first appearance of organisms to today) • The processes and lifetimes described in Table 1.5 will be discussed throughout the ...
- blogs@NTU
... functions is tremendously challenging because different compartments have similar or overlapping physicochemical properties. In addition, the nature of vesicular trafficking makes it difficult to distinguish between resident proteins with important functions in specific compartments and proteins tha ...
... functions is tremendously challenging because different compartments have similar or overlapping physicochemical properties. In addition, the nature of vesicular trafficking makes it difficult to distinguish between resident proteins with important functions in specific compartments and proteins tha ...
The Plastidial 2-C-Methyl-D-Erythritol 4-Phosphate
... Ziegelhoffer et al., 2000). Both farnesylated and geranylgeranylated proteins are involved in abscisic acid (ABA) signaling. The existence of farnesylated negative regulators of ABA signaling is inferred from the ABA hypersensitive phenotype of ENHANCED RESPONSE TO ABA1 (ERA1) mutants of Arabidopsis ...
... Ziegelhoffer et al., 2000). Both farnesylated and geranylgeranylated proteins are involved in abscisic acid (ABA) signaling. The existence of farnesylated negative regulators of ABA signaling is inferred from the ABA hypersensitive phenotype of ENHANCED RESPONSE TO ABA1 (ERA1) mutants of Arabidopsis ...
PDF
... outgrowths after fixation and staining indicated that results based on the two methods do not differ significantly (7 = 1-56, d.f. = 20, P > 0-10). Consequently, nuclear counts were performed by phase-contrast microscopy at 12 h intervals on each individual explant. Giant-cell nuclei were recognized ...
... outgrowths after fixation and staining indicated that results based on the two methods do not differ significantly (7 = 1-56, d.f. = 20, P > 0-10). Consequently, nuclear counts were performed by phase-contrast microscopy at 12 h intervals on each individual explant. Giant-cell nuclei were recognized ...
Adherent Neural Stem (NS) Cells from Fetal and
... substrate, we find that the adult NS cells are capable of differentiating into neurons and astrocytes (Fig. 2E,F). Differentiation is also induced by treatment with BMP4, possibly reflecting its endogenous role as a paracrine factor released by ependymal cells that promote astrocyte fate (Lim and othe ...
... substrate, we find that the adult NS cells are capable of differentiating into neurons and astrocytes (Fig. 2E,F). Differentiation is also induced by treatment with BMP4, possibly reflecting its endogenous role as a paracrine factor released by ependymal cells that promote astrocyte fate (Lim and othe ...
Text S1 Y2H Interactome Mapping The literature was curated to
... found in CF by multiple studies; 75% of the eliminated ORFs encode proteins that were identified in CF in only a single proteomic study, in comparison to those that remained for which 32% were detected in only a single study. From the final list, 339 ORFs that were sequence validated were provided b ...
... found in CF by multiple studies; 75% of the eliminated ORFs encode proteins that were identified in CF in only a single proteomic study, in comparison to those that remained for which 32% were detected in only a single study. From the final list, 339 ORFs that were sequence validated were provided b ...
Bio1A - Lec 6 slides File
... • built as a twisted double chain of actin subunits • structural role - to bear tension, resisting pulling forces within the cell ...
... • built as a twisted double chain of actin subunits • structural role - to bear tension, resisting pulling forces within the cell ...
NETosis: how vital is it?
... (ERK) pathway. NADPH assists in the translocation of neutrophil elastase from cytosolic granules into the nucleus where it aids in chromatin breakdown via histone cleavage. MPO is required for chromatin and nuclear envelope breakdown and granular mixing within the NET vacuole. Following 120 minutes ...
... (ERK) pathway. NADPH assists in the translocation of neutrophil elastase from cytosolic granules into the nucleus where it aids in chromatin breakdown via histone cleavage. MPO is required for chromatin and nuclear envelope breakdown and granular mixing within the NET vacuole. Following 120 minutes ...
final round
... a. They promote virulence b. They promote antigenicity c. They can be called a slime layer (correct answer) d. They can be stained using a negative stain BACK TO GAME ...
... a. They promote virulence b. They promote antigenicity c. They can be called a slime layer (correct answer) d. They can be stained using a negative stain BACK TO GAME ...
dependence of cell-type proportioning and sorting on cell cycle
... We had some indication that density gradients separate cells according to cell cycle ...
... We had some indication that density gradients separate cells according to cell cycle ...
cell cycle pp
... They may make their own growth factor They may convey a growth factor’s signal without the presence of the growth factor ...
... They may make their own growth factor They may convey a growth factor’s signal without the presence of the growth factor ...
(PTH).
... Adult body contains about 1kg calcium of which 99% is stored in skeleton About 1% of bone calcium is exchangeable with ...
... Adult body contains about 1kg calcium of which 99% is stored in skeleton About 1% of bone calcium is exchangeable with ...
Phenotypic Modulation of Smooth Muscle Cells
... Smooth muscle cells (SMCs) modulate their phenotype between proliferative and differentiated states in response to physiological and pathological cues. Insulin-like growth factor-I stimulates differentiation of SMCs by activating phosphoinositide-3-kinase (PI3K)Akt signaling. Foxo forkhead transcrip ...
... Smooth muscle cells (SMCs) modulate their phenotype between proliferative and differentiated states in response to physiological and pathological cues. Insulin-like growth factor-I stimulates differentiation of SMCs by activating phosphoinositide-3-kinase (PI3K)Akt signaling. Foxo forkhead transcrip ...
A Diffusible Signal from Arbuscular Mycorrhizal Fungi Elicits a
... medium only (Fig. 1). This result indicates that signaling molecules released in the medium by the AM fungus G. margarita are perceived by soybean cells and elicit a transient Ca21 elevation. A second addition of the same elicitor to cells just after dissipation of the first Ca21 signal (30 min) did ...
... medium only (Fig. 1). This result indicates that signaling molecules released in the medium by the AM fungus G. margarita are perceived by soybean cells and elicit a transient Ca21 elevation. A second addition of the same elicitor to cells just after dissipation of the first Ca21 signal (30 min) did ...
Derivation of haploid embryonic stem cells from mouse embryos
... haploid cells have been observed in egg cylinder stage parthenogenetic mouse embryos6, most cells in surviving embryos become diploid. Here we describe haploid mouse embryonic stem cells and show their application in forward genetic screening. Previous attempts to establish pluripotent stem-cell lin ...
... haploid cells have been observed in egg cylinder stage parthenogenetic mouse embryos6, most cells in surviving embryos become diploid. Here we describe haploid mouse embryonic stem cells and show their application in forward genetic screening. Previous attempts to establish pluripotent stem-cell lin ...
Sample Preparation for Peptides/Proteins
... spread over the plate. If you are spotting more than one sample on the plate, leave one spot between the samples to avoid spill overs from one well to another. Load the sample plate. ...
... spread over the plate. If you are spotting more than one sample on the plate, leave one spot between the samples to avoid spill overs from one well to another. Load the sample plate. ...
Chlamydia
... Chlamydia pass through a series of developmental forms while multiplying by binary fission. This is termed the "developmental cycle." Two morphologically different developmental forms with a continuous gradation of intermediates between them can be recognized. One is a small cell about 0.3 u in diam ...
... Chlamydia pass through a series of developmental forms while multiplying by binary fission. This is termed the "developmental cycle." Two morphologically different developmental forms with a continuous gradation of intermediates between them can be recognized. One is a small cell about 0.3 u in diam ...
The Control of Patterning and Morphogenesis during Root
... importance in defining the characteristics of the initials and the fate of their daughters, a model supported by studies of shoot development (Poethig, 1987, 1997, in this issue). Recently, an elegant set of laser ablation studies designed to address this issue was conducted on cells in the Arabidop ...
... importance in defining the characteristics of the initials and the fate of their daughters, a model supported by studies of shoot development (Poethig, 1987, 1997, in this issue). Recently, an elegant set of laser ablation studies designed to address this issue was conducted on cells in the Arabidop ...
Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).