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Product Monograph Template - Standard - GlaxoSmithKline
Product Monograph Template - Standard - GlaxoSmithKline

... Treatment of Initial Infection of Herpes Genitalis: 200 mg ( one teaspoonful of suspension [5 mL]) every 4 hours, 5 times daily for a total of 1 g daily for 10 days. Therapy should be initiated as early as possible following onset of signs and symptoms. Suppressive Therapy for Recurrent Herpes Genit ...
Omeprazole - School Nurse
Omeprazole - School Nurse

... unexplained weight loss; nausea or vomiting; or stomach pain. ...
Lay summary Page 2 Scientific discussion
Lay summary Page 2 Scientific discussion

... bioequivalence/bioavailability for such preparations where it is considered that the excipients will not interfere with bioavailability of the drug. In this instance there are no concerns as the same excipients are used in this formulation compared to that of the innovator. ...
Treatment in Acute MI
Treatment in Acute MI

... The 75-mg once-daily dose was approved by the FDA after the CAPRIE trial showed superior reduction of adverse cardiovascular events with clopidogrel versus aspirin The 75-mg once-daily dose had been used in CAPRIE because it produced inhibition of platelet aggregation equivalent to that produced by ...
ALLEGRA-D - hebust.edu.cn
ALLEGRA-D - hebust.edu.cn

... The pharmacokinetics of fexofenadine hydrochloride and pseudoephedrine hydrochloride when administered separately have been well characterized. Fexofenadine pharmacokinetics were linear for oral doses of fexofenadine hydrochloride up to 120 mg twice daily. The mean elimination half-life of fexofenad ...
Prescribing Information - PI
Prescribing Information - PI

... not been studied in the relief of acute symptoms and extra doses should not be used for that purpose. Acute symptoms should be treated with an inhaled short-acting beta2-agonist. When beginning BEVESPI AEROSPHERE, patients who have been taking inhaled, shortacting beta2-agonists on a regular basis ...
Prescribing Information as of XXXX ALLEGRA (fexofenadine hydrochloride)
Prescribing Information as of XXXX ALLEGRA (fexofenadine hydrochloride)

... Wheal and Flare. Human histamine skin wheal and flare studies following single and twice daily doses of 20 and 40 mg fexofenadine hydrochloride demonstrated that the drug exhibits an antihistamine effect by 1 hour, achieves maximum effect at 2 to 3 hours, and an effect is still seen at 12 hours. The ...
Methyldopa Methyldopa Description
Methyldopa Methyldopa Description

... If you have a fever and there seems to be no reason for it, check with your doctor. This is especially important during the first few weeks you take methyldopa, since fever may be a sign of a serious reaction to methyldopa. Before having any kind of surgery (including dental surgery) or emergency tr ...
NEW ZEALAND DATA SHEET Ospamox
NEW ZEALAND DATA SHEET Ospamox

... Resistant Gram-positive aerobes include: Staphylococcus (beta-lactamase producing strains). Resistant Gram-negative aerobes include: Acinetobacter spp., Citrobacter spp., Enterobacter spp., ...
Quinine Sulphate Tablets 200mg [jeb]
Quinine Sulphate Tablets 200mg [jeb]

... have been ruled out, and when non-pharmacological measures have not worked. Quinine sulfate should not be used for this indication during pregnancy (see Section 4.6). Quinine may cause unpredictable serious and life-threatening thrombocytopenia, which is thought to be an idiosyncratic hypersensitivi ...
ISOPTIN Ò SR 240mg
ISOPTIN Ò SR 240mg

... have shown effectiveness of doses similar to the effective doses of Isoptin (immediate release) in hypertensive patients. Plasma verapamil levels are not directly related to antihypertensive efficacy at the dosages usually administered (240 to 480mg/day). In healthy man, orally administered Isoptin ...
Asthma - The Rx Consultant
Asthma - The Rx Consultant

... because prescription drugs generally provide better control with fewer side effects. Drug therapy should be implemented in a step-wise manner based on the severity of the disease.2 The national guidelines describe four classes of asthma severity, determined by the frequency of symptoms and measureme ...
10 medicinal plants from pakistan - UiO
10 medicinal plants from pakistan - UiO

... 10 SELECTED MEDICINAL PLANTS OF PAKISTAN ................................................................................... 18 INTRODUCTION ..................................................................................................................................... 19 ISLAMIC REPUBLIC OF PA ...
(Soma): prescribing indications
(Soma): prescribing indications

... 400 mg tablet which would yield a meprobamate concentration of approximately 8.0 ug/mL. Pharmacokinetics Absorption The pharmacokinetics of carisoprodol was determined in a small in vivo biostudy of 5 men and 5 women. When the dose was normalized to 350 mg, the mean peak plasma concentration (Cmax) ...
Asthma, COPD, and Allergic Rhinitis
Asthma, COPD, and Allergic Rhinitis

... African-American patients compared to Caucasians ...
Rx and OTC medications containing acetaminophen
Rx and OTC medications containing acetaminophen

... Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even when used as recommended. While serious, life-threatening, or fatal respiratory depression can occur at any time during the use of XARTEMIS XR, the risk is greatest during the initiation of the ...
Linköping University Post Print Effects of the oral, direct thrombin inhibitor
Linköping University Post Print Effects of the oral, direct thrombin inhibitor

... with these drugs are that the patients are given a fixed dose and that no monitoring is required. The first to reach phase III clinical trials, ximelagatran, was not approved for clinical routine use due to side effects on the liver (3-5). Ximelagatran is a prodrug, metabolised to the active inhibit ...
Low Molecular Weight Heparins : Basic and Applied Considerations
Low Molecular Weight Heparins : Basic and Applied Considerations

... Currently, several newer agents are being investigated as possible substitutes for heparin. These new agents include antithrombin, anti-Xa, anti-TF, heparinoids, oral formulations of heparin, glycosaminoglycans mixtures, activated protein C and biotechnology derived SERPINS such as the recombinant A ...
Posanol (Posaconazole)
Posanol (Posaconazole)

... moderate or severe renal impairment (eGFR <50 mL/min), unless an assessment of the benefit/risk to the patient justifies the use of POSANOL® Solution for Injection. Serum creatinine levels should be closely monitored in these patients, and, if increases occur, consideration should be given to chang ...
PRODUCT MONOGRAPH PrLINCOCIN® Lincomycin injection USP
PRODUCT MONOGRAPH PrLINCOCIN® Lincomycin injection USP

... treatment did not result in any drug related abnormalities (physical, dental or developmental) when compared with the control group. The lincomycin injection formulation contains benzyl alcohol. The preservative benzyl alcohol has been associated with serious adverse events, including the “gasping s ...
Product Monograph CEFTIN
Product Monograph CEFTIN

... The concomitant administration of aminoglycosides and some cephalosporins has caused nephrotoxicity. There is no evidence that CEFTIN®, when administered alone, is nephrotoxic, although transient elevations of BUN and serum creatinine have been observed in clinical studies. However, the effect of a ...
Basics Pharmacology Review - Dr. Roland Halil
Basics Pharmacology Review - Dr. Roland Halil

... – Only very specific contraindications to pursuing therapy ...
Antifungals and their use in veterinary ophthalmology - GEAC-UFV
Antifungals and their use in veterinary ophthalmology - GEAC-UFV

... described [35]; however, only AMB, natamycin, and nystatin are of practical interest for the treatment of ocular fungal infections [35,37]. Polyenes are unstable insoluble chemicals that are poorly absorbed, with limited penetration into the eye, cerebrospinal fluid (CSF), and joint capsule [35,37–39 ...
Genvoya - Gilead
Genvoya - Gilead

... -------------------------------DRUG INTERACTIONS------------------------------• GENVOYA should not be administered with other antiretroviral medications for treatment of HIV-1 infection. (7.1) • GENVOYA can alter the concentration of drugs metabolized by CYP3A or CYP2D6. Drugs that induce CYP3A can ...
Zathrin side effects azithromycin medications
Zathrin side effects azithromycin medications

... azithromycin medications What can result Zithromax a report empty zathrin side effects azithromycin medications or and dark the zathrin side effects azithromycin medications colored stools or fainting) may hours. In and 2013 Buy Drug FDA USA Zithromax (which it antacids on patients of zathrin side e ...
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Dydrogesterone



Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.
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