Lineage Commitment During T cell Development
... Identify TF that regulate key CD4 vs CD8 specific target genes (CD4, CD8, perforin, CD40L, etc) Gene KO of candidate TF and assess impact on CD4, CD8 T cell development. (embryonic lethality, blocks at earlier stages of development (T commitment, TCRb checkpoint, etc) ...
... Identify TF that regulate key CD4 vs CD8 specific target genes (CD4, CD8, perforin, CD40L, etc) Gene KO of candidate TF and assess impact on CD4, CD8 T cell development. (embryonic lethality, blocks at earlier stages of development (T commitment, TCRb checkpoint, etc) ...
Arabidopsis mutants in sphingolipid synthesis as tools to
... therefore determine disease susceptibility. However, at the same time, the intercellular communication regarding other defense molecules such as sRNAs must persist in order to establish a systemic response of resistance. In this direction, it has been demonstrated that the synthesis of siRNAs (silen ...
... therefore determine disease susceptibility. However, at the same time, the intercellular communication regarding other defense molecules such as sRNAs must persist in order to establish a systemic response of resistance. In this direction, it has been demonstrated that the synthesis of siRNAs (silen ...
Document
... iGenetics Regulation of cell division in normal cells Try iactivity in chapter 10 online – tracking down the cause of cancer ...
... iGenetics Regulation of cell division in normal cells Try iactivity in chapter 10 online – tracking down the cause of cancer ...
Cyclin Dependent Kinases and Cell Cycle Control
... of mitotic onset and proposed that wee1 and cdc2 acted together in a regulatory network controlling the onset of mitosis. Next it was shown that cdc2 had a role controlling the onset of S-phase. This came about as a consequence of a survey of cdc mutants to look for those which blocked in G1 phase p ...
... of mitotic onset and proposed that wee1 and cdc2 acted together in a regulatory network controlling the onset of mitosis. Next it was shown that cdc2 had a role controlling the onset of S-phase. This came about as a consequence of a survey of cdc mutants to look for those which blocked in G1 phase p ...
PDF with detailed project information
... binding. Importantly, our experimental approach is suitable not only for endogenous small molecules, but also for the identification of protein partners of exogenous compounds, such as drugs and herbicides. At present, the small molecule signalling group (established in February 2015) comprises two ...
... binding. Importantly, our experimental approach is suitable not only for endogenous small molecules, but also for the identification of protein partners of exogenous compounds, such as drugs and herbicides. At present, the small molecule signalling group (established in February 2015) comprises two ...
7.2 powerpoint
... The composition of nearly all cell membranes is a double-layered sheet called a lipid bilayer, which gives cell membranes a flexible structure and forms a strong barrier between the cell and its surroundings. ...
... The composition of nearly all cell membranes is a double-layered sheet called a lipid bilayer, which gives cell membranes a flexible structure and forms a strong barrier between the cell and its surroundings. ...
Physico-chemical characteristics of cell walls from Arabidopsis
... endo-a-L-arabinanase released about 2.5-fold more of the total wall arabinose at day 14 than at days 4 and 8 while the percentage of total wall galactose released by the endo(1,4)-b-D-galactanase gradually decreased during the cell culture. The a-L-arabinofuranosidase released about 50% of total wal ...
... endo-a-L-arabinanase released about 2.5-fold more of the total wall arabinose at day 14 than at days 4 and 8 while the percentage of total wall galactose released by the endo(1,4)-b-D-galactanase gradually decreased during the cell culture. The a-L-arabinofuranosidase released about 50% of total wal ...
The Plant Extracellular Matrix: News from the Cell`s Frontier
... flotation centrifugation, and a sequencedependent glucanase was used to show that the synthase produced the expected products, cellotriosyl and cellotetraosyl unit structures, in vitro (Gibeaut and Carpita, 1994). However, a callose synthase activity was observed in the maize Golgi membranes in addi ...
... flotation centrifugation, and a sequencedependent glucanase was used to show that the synthase produced the expected products, cellotriosyl and cellotetraosyl unit structures, in vitro (Gibeaut and Carpita, 1994). However, a callose synthase activity was observed in the maize Golgi membranes in addi ...
The Plant Extracellular Matrix: News from the Cell`s
... flotation centrifugation, and a sequencedependent glucanase was used to show that the synthase produced the expected products, cellotriosyl and cellotetraosyl unit structures, in vitro (Gibeaut and Carpita, 1994). However, a callose synthase activity was observed in the maize Golgi membranes in addi ...
... flotation centrifugation, and a sequencedependent glucanase was used to show that the synthase produced the expected products, cellotriosyl and cellotetraosyl unit structures, in vitro (Gibeaut and Carpita, 1994). However, a callose synthase activity was observed in the maize Golgi membranes in addi ...
Autophagy in Tobacco BY-2 Cells Cultured under
... polymorpha), 35 autophagy-related proteins (Atgs) have been identified (Klionsky et al. 2003). Seventeen of these proteins, which are evolutionarily conserved, play an essential role in autophagosome formation (Hanaoka et al. 2002, Inoue and Klionsky 2010). One of these proteins, the ubiquitin-like ...
... polymorpha), 35 autophagy-related proteins (Atgs) have been identified (Klionsky et al. 2003). Seventeen of these proteins, which are evolutionarily conserved, play an essential role in autophagosome formation (Hanaoka et al. 2002, Inoue and Klionsky 2010). One of these proteins, the ubiquitin-like ...
Untitled - University of Guelph
... conveys the fact that, during development, one region of a cell grows differently from another, but it raises the question of how preferences for localized growth can be created within a cell. Furthermore, what molecular hierarchy might operate between cellular components for differential growth to ...
... conveys the fact that, during development, one region of a cell grows differently from another, but it raises the question of how preferences for localized growth can be created within a cell. Furthermore, what molecular hierarchy might operate between cellular components for differential growth to ...
Nuclear -Tubulin during Acentriolar Plant Mitosis
... typical staining pattern is shown as stereopairs in Figure 2A. Optical sectioning of G2 nuclei confirmed that the ␥-tubulin spots were inside the nuclei, adjacent to the chromatin. However, ␥-tubulin also was found on the nuclear surface, decorating perinuclear microtubules that were focused to the ...
... typical staining pattern is shown as stereopairs in Figure 2A. Optical sectioning of G2 nuclei confirmed that the ␥-tubulin spots were inside the nuclei, adjacent to the chromatin. However, ␥-tubulin also was found on the nuclear surface, decorating perinuclear microtubules that were focused to the ...
Cell shape determination in Escherichia coli
... may be sensed as a change in cytoplasmic turgor pressure, hence a change in the stress placed on the cell envelope. The stress theory of morphogenesis is discussed in detail by Harold in this issue. It should be emphasized, however, that there are other possible transduction mechanisms, for example, ...
... may be sensed as a change in cytoplasmic turgor pressure, hence a change in the stress placed on the cell envelope. The stress theory of morphogenesis is discussed in detail by Harold in this issue. It should be emphasized, however, that there are other possible transduction mechanisms, for example, ...
immunohistological study of mannan polysaccharides in poplar stem
... Mannan polysaccharides serve as storage reserves in seeds and as structure elements in cell walls, but they may also perform other important functions during plant growth. As one of the major hemicelluloses in angiosperm wood, little is known about the presence and localization of mannan polysacchar ...
... Mannan polysaccharides serve as storage reserves in seeds and as structure elements in cell walls, but they may also perform other important functions during plant growth. As one of the major hemicelluloses in angiosperm wood, little is known about the presence and localization of mannan polysacchar ...
CELL STRUCTURE EXPLORATION ACTIVITIES
... This packet contains different activities that are all about cells. The activities may be done in any order unless The Text: Organization of Life (pages 4!8) of Cells, Heredity, a by Holt. follow what we do as a I say otherwise, EXCEPT FOR # 12—DO THAT ONE LAST! They will pretty ...
... This packet contains different activities that are all about cells. The activities may be done in any order unless The Text: Organization of Life (pages 4!8) of Cells, Heredity, a by Holt. follow what we do as a I say otherwise, EXCEPT FOR # 12—DO THAT ONE LAST! They will pretty ...
reviews - Lab. Biodados UFMG
... inactivation in mouse retinal progenitors results in cellautonomous defects in cell cycle exit, specific differentiation defects, proliferation in differentiating cells and increased cell death. Although loss of Rb alone is not sufficient for brain cancer or retinoblastoma development in mice, simil ...
... inactivation in mouse retinal progenitors results in cellautonomous defects in cell cycle exit, specific differentiation defects, proliferation in differentiating cells and increased cell death. Although loss of Rb alone is not sufficient for brain cancer or retinoblastoma development in mice, simil ...
The Arabidopsis Callose Synthase Gene GSL8 Is
... alleles. In addition, gsl8 mutants and inducible RNA interference lines of GSL8 showed reduced callose deposition at cell plates and/or new cell walls. Together, these data show that the GSL8 gene encodes a putative callose synthase required for cytokinesis and seedling maturation. In addition, gsl8 ...
... alleles. In addition, gsl8 mutants and inducible RNA interference lines of GSL8 showed reduced callose deposition at cell plates and/or new cell walls. Together, these data show that the GSL8 gene encodes a putative callose synthase required for cytokinesis and seedling maturation. In addition, gsl8 ...
equisetum - Natuurtijdschriften
... trichoblast is helicoidalwith the sive lamellae and with the ...
... trichoblast is helicoidalwith the sive lamellae and with the ...
A Model-Based Approach for Automated In Vitro Cell - LISA
... (labeled Si in Fig. 2C). The heights of these Aext and Aint triangles are determined by radii rext and rint, respectively, where rint ⬍ rext (e.g., our experiments were performed with rint ⫽ 0.5rext, with rext ⫽ 30 pixels as initial value, i.e., a value a little higher than the average size of the c ...
... (labeled Si in Fig. 2C). The heights of these Aext and Aint triangles are determined by radii rext and rint, respectively, where rint ⬍ rext (e.g., our experiments were performed with rint ⫽ 0.5rext, with rext ⫽ 30 pixels as initial value, i.e., a value a little higher than the average size of the c ...
The endoplasmic reticulum exerts control over organelle streaming
... movement. Here we tested a role of the endoplasmic reticulum (ER) as propelling force for type cells and mutants with compromised ER structure and streaming, we demonstrate that cytoplasmic streaming undergoes profound changes during cell expansion and that it depends on motor forces co-exerted by t ...
... movement. Here we tested a role of the endoplasmic reticulum (ER) as propelling force for type cells and mutants with compromised ER structure and streaming, we demonstrate that cytoplasmic streaming undergoes profound changes during cell expansion and that it depends on motor forces co-exerted by t ...
Phragmoplastin dynamics: multiple forms
... and Falbel, 2002). This is based largely on observations from electron microscopy. A recent study on the formation of syncytial-type cell plates in the endosperm revealed that vesicles that are attached to the phragmoplast microtubules have a pair of kinked, rodshaped structures, resembling kinesin- ...
... and Falbel, 2002). This is based largely on observations from electron microscopy. A recent study on the formation of syncytial-type cell plates in the endosperm revealed that vesicles that are attached to the phragmoplast microtubules have a pair of kinked, rodshaped structures, resembling kinesin- ...
chapter 7 a tour of the cell
... 1. Microscopes provide windows to the world of the cell • The discovery and early study of cells progressed with the invention and improvement of microscopes in the 17th century. • In a light microscope (LMs) visible light passes through the specimen and then through glass lenses. • The lenses refr ...
... 1. Microscopes provide windows to the world of the cell • The discovery and early study of cells progressed with the invention and improvement of microscopes in the 17th century. • In a light microscope (LMs) visible light passes through the specimen and then through glass lenses. • The lenses refr ...
Oxidative Stress: Antagonistic Signaling for
... ROS, but this is hard to discern when key information on cellular physiological states is lacking. The signaling in cells producing ROS but not suffering oxidative stress may be quite different from that in cells suffering oxidative stress and consequent cell death. ...
... ROS, but this is hard to discern when key information on cellular physiological states is lacking. The signaling in cells producing ROS but not suffering oxidative stress may be quite different from that in cells suffering oxidative stress and consequent cell death. ...
Identification ofPseudomonas syringaetype III effectors that can
... capable of suppressing the HR elicited by P. syringae phaseolicola on Nicotiana benthamiana plants (Espinosa et al., 2003). These results prompted us to expand our screen for HR suppressors to include many of the recently identi®ed DC3000 effectors (Collmer et al., 2002). To do this, we used the pHI ...
... capable of suppressing the HR elicited by P. syringae phaseolicola on Nicotiana benthamiana plants (Espinosa et al., 2003). These results prompted us to expand our screen for HR suppressors to include many of the recently identi®ed DC3000 effectors (Collmer et al., 2002). To do this, we used the pHI ...
Programmed cell death
Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. PCD is carried out in a regulated process, which usually confers advantage during an organism's life-cycle. For example, the differentiation of fingers and toes in a developing human embryo occurs because cells between the fingers apoptose; the result is that the digits are separate. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.Apoptosis and autophagy are both forms of programmed cell death, but necrosis is a non-physiological process that occurs as a result of infection or injury.Necrosis is the death of a cell caused by external factors such as trauma or infection and occurs in several different forms. Recently a form of programmed necrosis, called necroptosis, has been recognized as an alternate form of programmed cell death. It is hypothesized that necroptosis can serve as a cell-death backup to apoptosis when the apoptosis signaling is blocked by endogenous or exogenous factors such as viruses or mutations.