Soft X-Ray-Induced Decomposition of Amino Acids: An XPS, Mass
... spectra have complicated asymmetric shapes due to contributions of several functional groups and shake-up satellites.3 For the assignment of the spectral features, it must be taken into account that the form of amino acids that is most stable in the solid state is a zwitterion with a protonated amin ...
... spectra have complicated asymmetric shapes due to contributions of several functional groups and shake-up satellites.3 For the assignment of the spectral features, it must be taken into account that the form of amino acids that is most stable in the solid state is a zwitterion with a protonated amin ...
LYSOSTAPHIN AS AN ALTERNATE THERAPY IN METHICILLIN RESISTANT STAPHYLOCOCCUS
... Various new drugs have been tested against MRSA out of them lysostaphin has shown promising results. The potential use of lysostaphin-lysozyme combination for topical therapy of staphylococcal infections resistant to other antibiotics has been demonstrated by Cisani et al 1982[10]. In view of the pr ...
... Various new drugs have been tested against MRSA out of them lysostaphin has shown promising results. The potential use of lysostaphin-lysozyme combination for topical therapy of staphylococcal infections resistant to other antibiotics has been demonstrated by Cisani et al 1982[10]. In view of the pr ...
Enantioselective Synthesis of Cyclic Ethers through a Vanadium
... The vanadium-catalyzed oxidation of 1, using CHCl3 as the solvent and L1 (Table 1, entry 2) or L2 (Table 1, entry 4) as the ligand, cleanly afforded 2,5-trans-THP 2 (THP = tetrahydropyran; d.r. = > 95:5) with excellent diastereoselectivity accompanied by only minor amounts of THF 2 a (d.r. = 1:1) an ...
... The vanadium-catalyzed oxidation of 1, using CHCl3 as the solvent and L1 (Table 1, entry 2) or L2 (Table 1, entry 4) as the ligand, cleanly afforded 2,5-trans-THP 2 (THP = tetrahydropyran; d.r. = > 95:5) with excellent diastereoselectivity accompanied by only minor amounts of THF 2 a (d.r. = 1:1) an ...
video slide - Biology at Mott
... The discovery of ribozymes rendered obsolete the belief that all biological catalysts were proteins ...
... The discovery of ribozymes rendered obsolete the belief that all biological catalysts were proteins ...
13C NMR - Creighton Chemistry Webserver
... C - 13C spin-spin splitting is never observed almost no molecules have $ 2 13C in them: for example, the probability of hexane having two adjacent 13C is 0.011 x 0.011 x 0.29 = 3.5 x 10 -6 ...
... C - 13C spin-spin splitting is never observed almost no molecules have $ 2 13C in them: for example, the probability of hexane having two adjacent 13C is 0.011 x 0.011 x 0.29 = 3.5 x 10 -6 ...
Introduction to 3D-Structure Visualization and Homology Modeling
... HMMs-Evaluation & Structure Template - Target HMMs alignment) Assessment • Structure quality (resolution, ...
... HMMs-Evaluation & Structure Template - Target HMMs alignment) Assessment • Structure quality (resolution, ...
Microsoft Word
... considered unsuitable for precision polymer synthesis, in contrast to the ionic counterparts where the growing species are inherently repulsive to each other. One of the most effective methods for precise polymer synthesis is "living" polymerization, the first example of which discovered by Szwarc e ...
... considered unsuitable for precision polymer synthesis, in contrast to the ionic counterparts where the growing species are inherently repulsive to each other. One of the most effective methods for precise polymer synthesis is "living" polymerization, the first example of which discovered by Szwarc e ...
Chapter 18 - Aldehydes and Ketones
... • Hydration of Aldehydes and Ketones (18-14) Addition of water to the carbonyl is a good example illustrating the need to activate the carbonyl by protonation. This reaction is not a very useful reaction in the forward process since the carbonyl hydrate will rearrange to the carbonyl. However, when ...
... • Hydration of Aldehydes and Ketones (18-14) Addition of water to the carbonyl is a good example illustrating the need to activate the carbonyl by protonation. This reaction is not a very useful reaction in the forward process since the carbonyl hydrate will rearrange to the carbonyl. However, when ...
COOH HOOC COOH HOOC
... 2. Decarboxylation = elimination of carbon dioxide from acids or their salts at high temperatures in the presence of NaOH R−COONa + NaOH R−H + Na2CO3 ...
... 2. Decarboxylation = elimination of carbon dioxide from acids or their salts at high temperatures in the presence of NaOH R−COONa + NaOH R−H + Na2CO3 ...
PHYS 4xx Intro 2 1 PHYS 4xx Intro 2
... Sugar molecules are one component of DNA and of the peptidoglycan network of the bacterial cell wall. A single sugar molecule has the chemical formula (CH2O)n, the most biologically important sugars having n = 5 or 6. Examples of the conformations available for the glucose molecule (n = 6) are: ...
... Sugar molecules are one component of DNA and of the peptidoglycan network of the bacterial cell wall. A single sugar molecule has the chemical formula (CH2O)n, the most biologically important sugars having n = 5 or 6. Examples of the conformations available for the glucose molecule (n = 6) are: ...
RNA Biology: Structures to the people! | eLife
... Figure 1. The three dimensional structure of an RNA molecule can be predicted by combining MOHCA, deep sequencing and algorithms that predict secondary and tertiary structures in the RNA. (A) In MOHCA, copies of the RNA of interest that contain modified nucleotides—on average one per molecule—are ma ...
... Figure 1. The three dimensional structure of an RNA molecule can be predicted by combining MOHCA, deep sequencing and algorithms that predict secondary and tertiary structures in the RNA. (A) In MOHCA, copies of the RNA of interest that contain modified nucleotides—on average one per molecule—are ma ...
On The Determination of Enzyme Structure, Function, and
... the enzyme, but also its cellular location and regulation. For a chemical analysis of an enzyme, however, the most important aspects are knowing the structure of the enzyme at atomic detail and knowing the kinetics, that is, which substrate or substrates the enzyme binds, how fast the chemical react ...
... the enzyme, but also its cellular location and regulation. For a chemical analysis of an enzyme, however, the most important aspects are knowing the structure of the enzyme at atomic detail and knowing the kinetics, that is, which substrate or substrates the enzyme binds, how fast the chemical react ...
IOSR Journal of Applied Chemistry (IOSR-JAC) e-ISSN: 2278-5736.
... Asymmetric tridentate ligands have been extensively used in coordination chemistry [11] of nickel (II). The physical and chemical properties of transition metal complexes are greatly influenced by their structures and the coordination geometries by the ligand design. Transition metal complexes and S ...
... Asymmetric tridentate ligands have been extensively used in coordination chemistry [11] of nickel (II). The physical and chemical properties of transition metal complexes are greatly influenced by their structures and the coordination geometries by the ligand design. Transition metal complexes and S ...
Review Structural glycobiology: A game of snakes and ladders
... conditions. Characterization of this heterogeneous conformational ensemble has been a major obstacle impeding high-resolution structure determination of carbohydrates and acting as a bottleneck in the effort to understand the relationship between the carbohydrate structure and function. This challen ...
... conditions. Characterization of this heterogeneous conformational ensemble has been a major obstacle impeding high-resolution structure determination of carbohydrates and acting as a bottleneck in the effort to understand the relationship between the carbohydrate structure and function. This challen ...
Document
... REF: Page 738 OBJ: 23.1.1 Describe a functional group and give examples. NAT: B.2 STA: S.11.C.1.1.3 TOP: Describe a functional group and give examples. KEY: Functional groups MSC: 2 NOT: A functional group in an organic molecule is an atom or group of atoms that always reacts in a certain way. The a ...
... REF: Page 738 OBJ: 23.1.1 Describe a functional group and give examples. NAT: B.2 STA: S.11.C.1.1.3 TOP: Describe a functional group and give examples. KEY: Functional groups MSC: 2 NOT: A functional group in an organic molecule is an atom or group of atoms that always reacts in a certain way. The a ...
the chemistry of smell
... example, R1 is CH3CH2CH2, and R2 is CH3 in the ester shown above.) Esters generally have a sweet smell. ...
... example, R1 is CH3CH2CH2, and R2 is CH3 in the ester shown above.) Esters generally have a sweet smell. ...
methicillin-resistant staphyloccus aureus infections
... can and do cause diseases and make us sick and a microorganism that causes a disease is called a pathogen. But microorganisms - especially bacteria - are often not foreign. We all have microorganisms - millions and millions of them - in our stomach, in our noses and mouths, in our bowels, and on our ...
... can and do cause diseases and make us sick and a microorganism that causes a disease is called a pathogen. But microorganisms - especially bacteria - are often not foreign. We all have microorganisms - millions and millions of them - in our stomach, in our noses and mouths, in our bowels, and on our ...
Bottromycin
Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.