
Genetic Analysis of Muscle Development in Drosophila
... We set out to explore the genetic basis of these specificities by means of a genetic analysis of these loci. Within the context of the genetic analysis, specificity should be understood as a property of the genome to control a biological process (muscle fasciculation in this case) distinct from othe ...
... We set out to explore the genetic basis of these specificities by means of a genetic analysis of these loci. Within the context of the genetic analysis, specificity should be understood as a property of the genome to control a biological process (muscle fasciculation in this case) distinct from othe ...
Authors` version - The Computable Plant
... biosynthesis of L-leucine, is end-product inhibited by L-leucine. However, because the parallel pathways for L-valine and L-isoleucine biosynthesis are catalyzed by a set of bi-functional enzymes that bind substrates from either pathway, L-valine inhibition of the first enzyme specific for its biosy ...
... biosynthesis of L-leucine, is end-product inhibited by L-leucine. However, because the parallel pathways for L-valine and L-isoleucine biosynthesis are catalyzed by a set of bi-functional enzymes that bind substrates from either pathway, L-valine inhibition of the first enzyme specific for its biosy ...
DNA cytosine methylation in plant development
... Cytosine bases of the nuclear genome in higher plants are often extensively methylated. Cytosine methylation has been implicated in the silencing of both transposable elements (TEs) and endogenous genes, and loss of methylation may have severe functional consequences. The recent methylation profilin ...
... Cytosine bases of the nuclear genome in higher plants are often extensively methylated. Cytosine methylation has been implicated in the silencing of both transposable elements (TEs) and endogenous genes, and loss of methylation may have severe functional consequences. The recent methylation profilin ...
Feeney_ku_0099D_12934_DATA_1 - KU ScholarWorks
... Purpose: Oxidative post-translational modification of protein-bound tyrosine residues can have a significant impact on protein structure and function and thus may be important to physiological and pathological processes. Oxidative stress has been correlated with biological aging and many disease sta ...
... Purpose: Oxidative post-translational modification of protein-bound tyrosine residues can have a significant impact on protein structure and function and thus may be important to physiological and pathological processes. Oxidative stress has been correlated with biological aging and many disease sta ...
A genome-wide analysis of DNA methylation in buccal - VU-DARE
... average genome-wide heritability of DNA methylation was higher when restricting to the most variable CpG sites (for the top 10% CpGs of which methylation level varied most between subjects, the average heritability was 37%) 34. It was also found that gene body and intergenic regions showed higher a ...
... average genome-wide heritability of DNA methylation was higher when restricting to the most variable CpG sites (for the top 10% CpGs of which methylation level varied most between subjects, the average heritability was 37%) 34. It was also found that gene body and intergenic regions showed higher a ...
Nucleic acid vaccines against rickettsial diseases and methods of use
... have been developed against certain rickettsial diseases, for example against R. prowazekii and R. rickettsii. HoWever, these vaccines have major problems or disadvantages, including undesirable toxic reactions, difficulty in standardiZation, and expense (WoodWard, T. [1981] “Rick ...
... have been developed against certain rickettsial diseases, for example against R. prowazekii and R. rickettsii. HoWever, these vaccines have major problems or disadvantages, including undesirable toxic reactions, difficulty in standardiZation, and expense (WoodWard, T. [1981] “Rick ...
PROTEIN SUBCELLULAR LOCALIZATION
... WoLF PSORT was designed with dual localization in mind. The only dual localization category for which SWISS-PROT currently contains a significant number of entries is dual localization to the nucleus and cytosol. This is an important category of proteins, for example some transcription factors are r ...
... WoLF PSORT was designed with dual localization in mind. The only dual localization category for which SWISS-PROT currently contains a significant number of entries is dual localization to the nucleus and cytosol. This is an important category of proteins, for example some transcription factors are r ...
Functional features of RUNX1 mutants in acute
... RUNX1 and CBF are among the most frequent targets in leukemia through chromosomal translocations or gene mutations.10,11 With regard to the RUNX1 gene, different chromosomal translocations have been reported in human acute leukemias such as t(8;21)(q22;q22) generating the RUNX1-ETO fusion gene, t(1 ...
... RUNX1 and CBF are among the most frequent targets in leukemia through chromosomal translocations or gene mutations.10,11 With regard to the RUNX1 gene, different chromosomal translocations have been reported in human acute leukemias such as t(8;21)(q22;q22) generating the RUNX1-ETO fusion gene, t(1 ...
PDF
... florescence in the transgenic plants, we found that OsIAA9 is localized in the nucleus. When transfected into protoplasts isolated from rosette leaves of Arabidopsis, OsIAA9 repressed reporter gene expression, and the repression was partially released by exogenously IAA. These results suggest that O ...
... florescence in the transgenic plants, we found that OsIAA9 is localized in the nucleus. When transfected into protoplasts isolated from rosette leaves of Arabidopsis, OsIAA9 repressed reporter gene expression, and the repression was partially released by exogenously IAA. These results suggest that O ...
nitrogen assimilation and global regulation in escherichia coli
... Once ammonia is assimilated, it must be distributed in the correct ratios to a variety of compounds. The biosynthetic requirement of each nitrogen-containing metabolite (how much must be synthesized) can be calculated from the chemical composition of E. coli (the amount of each component that would ...
... Once ammonia is assimilated, it must be distributed in the correct ratios to a variety of compounds. The biosynthetic requirement of each nitrogen-containing metabolite (how much must be synthesized) can be calculated from the chemical composition of E. coli (the amount of each component that would ...
Mechanisms of translational regulation in bacteria
... the growing peptide chain is determined by triplets of nucleotides, so called codons. However, there are only 20 amino acids but 64 different triplets of nucleotides encoding them. Consequently, the genetic code is degenerate: Except for tryptophan and methionine, the amino acids are encoded by two, ...
... the growing peptide chain is determined by triplets of nucleotides, so called codons. However, there are only 20 amino acids but 64 different triplets of nucleotides encoding them. Consequently, the genetic code is degenerate: Except for tryptophan and methionine, the amino acids are encoded by two, ...
Identification of New Genes Involved in Meiosis by a Genetic Screen
... meiosis II four haploid daughter cells are formed from two haploid parent cells, hence it is called equational division. In meiosis I the homologous chromosomes undergo pairwise juxtaposition, followed by formation of chiasmata. Chiasmata is a cytologically detectable point of association between no ...
... meiosis II four haploid daughter cells are formed from two haploid parent cells, hence it is called equational division. In meiosis I the homologous chromosomes undergo pairwise juxtaposition, followed by formation of chiasmata. Chiasmata is a cytologically detectable point of association between no ...
Sun J, Ke J, Johnson JL, Nikolau BJ, Wurtele ES
... clones were isolated from approximately 200,000 recombinant bacteriophage. The longest of these, which we cal1 C A C 2 , was 1995 bp in length. Beginning at position 119 of the nucleotide sequence was an “ATG” codon, which initiated a 1614-bp open reading frame, the longest present on this cDNA. Ups ...
... clones were isolated from approximately 200,000 recombinant bacteriophage. The longest of these, which we cal1 C A C 2 , was 1995 bp in length. Beginning at position 119 of the nucleotide sequence was an “ATG” codon, which initiated a 1614-bp open reading frame, the longest present on this cDNA. Ups ...
Identification of a Vinyl Reductase Gene for
... Arabidopsis polymorphism collection database, and we confirmed that the DVR gene is located on the region covered by the BAC clones shown in Figure 3A. There were four open reading frames (ORFs) encoding putative reductases whose functions were not yet assigned. By sequencing these genes, we finally ...
... Arabidopsis polymorphism collection database, and we confirmed that the DVR gene is located on the region covered by the BAC clones shown in Figure 3A. There were four open reading frames (ORFs) encoding putative reductases whose functions were not yet assigned. By sequencing these genes, we finally ...
Chemistry 100 Second Homework
... molecules? (Be careful! Think about the shape of the molecule.) c. The C-F bond in polytetrafluoroethylene has a bond energy of about 504 kJ/mole. (As a comparison, the C-C single bond has a bond energy of 376 kJ/mole.) Would you expect polytetrafluoroethylene to be very reactive? Briefly explain yo ...
... molecules? (Be careful! Think about the shape of the molecule.) c. The C-F bond in polytetrafluoroethylene has a bond energy of about 504 kJ/mole. (As a comparison, the C-C single bond has a bond energy of 376 kJ/mole.) Would you expect polytetrafluoroethylene to be very reactive? Briefly explain yo ...
File - Catecholaminergic Polymorphic Ventricular
... attributed to RYR2 mutations only producing the arrhythmia phenotype in the ventricles of the heart, the chambers responsible for pumping blood though the entire body. Since the first symptom of CPVT is often cardiac arrest, most deaths occur without knowledge of even having the disorder (Ylanen et ...
... attributed to RYR2 mutations only producing the arrhythmia phenotype in the ventricles of the heart, the chambers responsible for pumping blood though the entire body. Since the first symptom of CPVT is often cardiac arrest, most deaths occur without knowledge of even having the disorder (Ylanen et ...
Functional Plant Biology
... nifH-based comparison of Frankia gene expression in nodules of A. glutinosa using microarray-based gene expression data (Tables 3, 4; based on Alloisio et al. 2010). While caution must be exercised in interpreting metadata derived from two different experiments (Tables 2–4), it can be seen that for ...
... nifH-based comparison of Frankia gene expression in nodules of A. glutinosa using microarray-based gene expression data (Tables 3, 4; based on Alloisio et al. 2010). While caution must be exercised in interpreting metadata derived from two different experiments (Tables 2–4), it can be seen that for ...
Translocation of proteins across the cell envelope of Gram
... To ensure the proper targeting and translocation across the membrane, secretory proteins are equipped with a signal peptide that is proteolytically removed by signal peptidases during or shortly after translocation [35]. In the general secretion pathway, two classes of signal peptides can be identi¢ ...
... To ensure the proper targeting and translocation across the membrane, secretory proteins are equipped with a signal peptide that is proteolytically removed by signal peptidases during or shortly after translocation [35]. In the general secretion pathway, two classes of signal peptides can be identi¢ ...
Inflammation and ER Stress Regulate Branched
... epididymal adipose tissue of high-fat-fed mice but not in inguinal fat. To assess whether the down-regulation of the BCAA pathway gene expression was adipose specific, a panel of enzymes was profiled in brown fat, muscle, and liver, and expression was found to not be affected and, in the case of liv ...
... epididymal adipose tissue of high-fat-fed mice but not in inguinal fat. To assess whether the down-regulation of the BCAA pathway gene expression was adipose specific, a panel of enzymes was profiled in brown fat, muscle, and liver, and expression was found to not be affected and, in the case of liv ...
Gene Section MYB (v-myb myeloblastosis viral oncogene homolog (avian))
... The NRD negatively regulates the trans-activating and transforming capacity of MYB. Several motifs within the NRD have been identified, including a Heptad Leucine Repeat (HLR) and a highly conserved EVES motif. Disruption of the HLR motif results in enhancement of MYB's trans-activating and transfor ...
... The NRD negatively regulates the trans-activating and transforming capacity of MYB. Several motifs within the NRD have been identified, including a Heptad Leucine Repeat (HLR) and a highly conserved EVES motif. Disruption of the HLR motif results in enhancement of MYB's trans-activating and transfor ...
[7] Semisynthesis of Proteins Containing Selenocysteine
... peptide ligation through a C-tenninal thioester and an N-tenninal cysteine residue (Fig. 1). Using this general method, we envision four distinct strategies for introducing selenocysteine into a protein, as summarized in Table I. 1. A peptide that contains an embedded selenocysteine residue and C-te ...
... peptide ligation through a C-tenninal thioester and an N-tenninal cysteine residue (Fig. 1). Using this general method, we envision four distinct strategies for introducing selenocysteine into a protein, as summarized in Table I. 1. A peptide that contains an embedded selenocysteine residue and C-te ...
M2 RNA Pol Ⅰ genes
... A RNA Pol II only transcribes protein-coding genes. B the TATA box has a role in transcription efficiency but not in positioning the start of transcriphon. C TBP binds to the TAT A box. D Enhancers typically lie 100-200 bp upstream from the start of transcription. 6. Which one of the following state ...
... A RNA Pol II only transcribes protein-coding genes. B the TATA box has a role in transcription efficiency but not in positioning the start of transcriphon. C TBP binds to the TAT A box. D Enhancers typically lie 100-200 bp upstream from the start of transcription. 6. Which one of the following state ...
In vivo analysis of straight-chain and branched
... very high level of intact butyrate incorporation is, however, more consistent with the direct utilization of butyryl-CoA for fatty acid biosynthesis using either a Type I or Type II fatty acid synthase (Fig. 1). In contrast, a low level of intact hexanoate incorporation into the straight-chain fatty ...
... very high level of intact butyrate incorporation is, however, more consistent with the direct utilization of butyryl-CoA for fatty acid biosynthesis using either a Type I or Type II fatty acid synthase (Fig. 1). In contrast, a low level of intact hexanoate incorporation into the straight-chain fatty ...
Feodor Lynen - Nobel Lecture
... acid produced by yeast from acetate is formed via citric acid7. Sonderhoff’s experiments with deuterated acetic acid led to another important discovery. In the analysis of the yeast cells themselves, it was found that while the carbohydrate fraction contained only insignificant quantities of deuteri ...
... acid produced by yeast from acetate is formed via citric acid7. Sonderhoff’s experiments with deuterated acetic acid led to another important discovery. In the analysis of the yeast cells themselves, it was found that while the carbohydrate fraction contained only insignificant quantities of deuteri ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.