
Nodal signaling and the zebrafish organizer
... These mutant phenotypes strongly resemble previously described defects induced by overactivation or inhibition of BMP signaling in Xenopus (De Robertis and Sasai, 1996; Harland and Gerhart, 1997). Indeed, epistatic analysis and molecular cloning has identified five genes of the dorsal-ventral group ...
... These mutant phenotypes strongly resemble previously described defects induced by overactivation or inhibition of BMP signaling in Xenopus (De Robertis and Sasai, 1996; Harland and Gerhart, 1997). Indeed, epistatic analysis and molecular cloning has identified five genes of the dorsal-ventral group ...
Calculating the Number of Genes
... – all offspring get their alleles from either a wildtype, or inverted chromosome, ...
... – all offspring get their alleles from either a wildtype, or inverted chromosome, ...
Genome Visualisation and Annotation Tools: Artemis and ACT
... qualifiers for a particular term. For example using the word ‘pseudogene’ will take you to the next feature with the word ‘pseudogene’ in any of its qualifiers. Note how repeated clicking of the ‘Goto’ button takes you through the pseudogenes as they occur on the chromsome. ...
... qualifiers for a particular term. For example using the word ‘pseudogene’ will take you to the next feature with the word ‘pseudogene’ in any of its qualifiers. Note how repeated clicking of the ‘Goto’ button takes you through the pseudogenes as they occur on the chromsome. ...
International Agency for Research on Cancer (IARC)
... embryos to aflatoxin B1 induced a high incidence of hepatocellular adenomas and carcinomas. Intraperitoneal administration of aflatoxin B1 to rats during pregnancy and lactation induced benign and malignant tumours in mothers and their progeny in the liver and in various other organs, including thos ...
... embryos to aflatoxin B1 induced a high incidence of hepatocellular adenomas and carcinomas. Intraperitoneal administration of aflatoxin B1 to rats during pregnancy and lactation induced benign and malignant tumours in mothers and their progeny in the liver and in various other organs, including thos ...
A General Model of Codon Bias Due to GC Mutational Bias
... patterns of codons used without recourse to the added complexity of including non-synonymous mutations. Consider the codons relating to any particular amino acid. For any two codons X and Y that differ by a single nucleotide, we assume that the rates of mutation from X to Y and from Y to X are the s ...
... patterns of codons used without recourse to the added complexity of including non-synonymous mutations. Consider the codons relating to any particular amino acid. For any two codons X and Y that differ by a single nucleotide, we assume that the rates of mutation from X to Y and from Y to X are the s ...
Chromosomes in Saccharomyces cerevisiae
... Directed chromosome breakage. One possible explanation for the failure of artificial chromosomes to segregate as faithfully as their natural counterparts is that they carry telomeres derived from those of the Tetrahymena ribosomal DNA plasmid (Tr ends [24]) rather than those found on natural yeast c ...
... Directed chromosome breakage. One possible explanation for the failure of artificial chromosomes to segregate as faithfully as their natural counterparts is that they carry telomeres derived from those of the Tetrahymena ribosomal DNA plasmid (Tr ends [24]) rather than those found on natural yeast c ...
TCF11/Nrf1 overexpression increases the intracellular
... the luciferase activity in cell lysates was measured. A 2.7fold increase in luciferase activity was observed at the highest concentration of the TCF11/Nrf1 expression plasmid used (Fig. 2). The same results were obtained when cells were transfected using calcium phosphate and including CAT as intern ...
... the luciferase activity in cell lysates was measured. A 2.7fold increase in luciferase activity was observed at the highest concentration of the TCF11/Nrf1 expression plasmid used (Fig. 2). The same results were obtained when cells were transfected using calcium phosphate and including CAT as intern ...
Soybean Meal – An Exceptional Protein Source
... Soybean meal has long been considered an outstanding source of supplemental protein in diets for livestock and poultry. In fact, soybean meal is sometimes referred to as the "gold standard" because other protein sources are often compared to it. Soybean meal is rich in highly digestible protein, and ...
... Soybean meal has long been considered an outstanding source of supplemental protein in diets for livestock and poultry. In fact, soybean meal is sometimes referred to as the "gold standard" because other protein sources are often compared to it. Soybean meal is rich in highly digestible protein, and ...
genetics genetics - Cystic Fibrosis Association of New Zealand
... protection from diseases such as cholera) over non-carriers, which would explain why the faulty gene is so common. Most people find out they are carriers when: a) they have a child with CF, or b) a close relative is affected and they’re tested. ...
... protection from diseases such as cholera) over non-carriers, which would explain why the faulty gene is so common. Most people find out they are carriers when: a) they have a child with CF, or b) a close relative is affected and they’re tested. ...
Cloning, Sequencing, and Characterization of Luciola italica
... variety of biochemical experiments. It is a particularly useful as a tool in the ultrasensitive detection of ATP, a reporter gene for monitoring transcriptional activity, a biosensor for chemical toxins, a probe for monitoring protein folding in vivo, and a probe for the actions of local anesthetics ...
... variety of biochemical experiments. It is a particularly useful as a tool in the ultrasensitive detection of ATP, a reporter gene for monitoring transcriptional activity, a biosensor for chemical toxins, a probe for monitoring protein folding in vivo, and a probe for the actions of local anesthetics ...
Modeling Trabecular Microstructure Evolution via Genetic Algorithm by Samuel W. L. Shames
... the same set of points under the same stress state at three stages of evolution. The figure shows how drastically the microstructure of the system can change in only a small number of generations and how the general tendency is for the number of struts with a large strain energy—bright red struts—to ...
... the same set of points under the same stress state at three stages of evolution. The figure shows how drastically the microstructure of the system can change in only a small number of generations and how the general tendency is for the number of struts with a large strain energy—bright red struts—to ...
Homeotic genes regulate the spatial expression
... 1032 R. Renter and others morphology by coordinating the spatial and temporal transcription patterns of target or 'realizator' genes (Garcia-Bellido, 1977). In the epidermis, the nervous system, and the visceral mesoderm, cross-regulatory interactions have been observed among the homeotic genes; th ...
... 1032 R. Renter and others morphology by coordinating the spatial and temporal transcription patterns of target or 'realizator' genes (Garcia-Bellido, 1977). In the epidermis, the nervous system, and the visceral mesoderm, cross-regulatory interactions have been observed among the homeotic genes; th ...
Sequence Polymorphisms at the Reduced Dormancy 5
... Y.X., I.F. and W.J.J.S. designed the research. Y.X., B.S., G.N., and K.K. performed research. Y.X., B.S., G.N., and K.K. analyzed data. Y.X. and W.J.J.S. wrote the article. Funding for this work is from Max-Planck Society. ...
... Y.X., I.F. and W.J.J.S. designed the research. Y.X., B.S., G.N., and K.K. performed research. Y.X., B.S., G.N., and K.K. analyzed data. Y.X. and W.J.J.S. wrote the article. Funding for this work is from Max-Planck Society. ...
Lecture_6-2
... BLOSUM matrices are based on local alignments. BLOSUM stands for blocks substitution matrix. BLOSUM62 is a matrix calculated from comparisons of sequences with less than 62% identical sites. ...
... BLOSUM matrices are based on local alignments. BLOSUM stands for blocks substitution matrix. BLOSUM62 is a matrix calculated from comparisons of sequences with less than 62% identical sites. ...
History of Discoveries in Molecular Biology
... The idea was not the product of a painstaking laboratory discipline, but was conceived while cruising in a Honda Civic on Highway 128 from San Francisco to Mendocino. "I do my best thinking while driving," the scientist with the tanned face and bleached hair once explained. For this brilliant idea b ...
... The idea was not the product of a painstaking laboratory discipline, but was conceived while cruising in a Honda Civic on Highway 128 from San Francisco to Mendocino. "I do my best thinking while driving," the scientist with the tanned face and bleached hair once explained. For this brilliant idea b ...
Glycolic acid production in the engineered yeasts Saccharomyces
... production [8-12]. However, no eukaryotic microbe has been used for glycolic acid production to the best of our knowledge. With E. coli, the fermentation conditions are limited due to their need to be maintained close to a neutral pH. The benefit with many fungal species is their tolerance towards l ...
... production [8-12]. However, no eukaryotic microbe has been used for glycolic acid production to the best of our knowledge. With E. coli, the fermentation conditions are limited due to their need to be maintained close to a neutral pH. The benefit with many fungal species is their tolerance towards l ...
Increased sex chromosome expression and epigenetic
... 2006). However, the X and Y chromosomes are continually remodelled during the transition between meiosis and spermiogenesis, and histone modifications associated with transcriptionally active chromatin [e.g. histone acetylation and histone H3 dimethylated on lysine 4 (H3K4me2)] are also enriched on ...
... 2006). However, the X and Y chromosomes are continually remodelled during the transition between meiosis and spermiogenesis, and histone modifications associated with transcriptionally active chromatin [e.g. histone acetylation and histone H3 dimethylated on lysine 4 (H3K4me2)] are also enriched on ...
Structural Features of Angiotensin-I Converting Enzyme Catalytic Sites
... amino acids between the first two ligands. On the other hand, the long spacers usually found in various metallopeptidase subfamilies could vary from 5 to over 100 amino acids. The length of the spacer between the two first ligands belonging to the same binding motif often characterizes the secondary ...
... amino acids between the first two ligands. On the other hand, the long spacers usually found in various metallopeptidase subfamilies could vary from 5 to over 100 amino acids. The length of the spacer between the two first ligands belonging to the same binding motif often characterizes the secondary ...
Recombinant thrombin receptor and related pharmaceuticals
... receptor permits the design of agonist and antagonist com pounds Which are useful diagnostically and therapeutically. The availability of the thrombin receptor also permits pro duction of antibodies speci?cally immunoreactive With the receptor per se or With speci?c regions thereof Which are ...
... receptor permits the design of agonist and antagonist com pounds Which are useful diagnostically and therapeutically. The availability of the thrombin receptor also permits pro duction of antibodies speci?cally immunoreactive With the receptor per se or With speci?c regions thereof Which are ...
understanding heredity
... of his research with rabbits, guinea pigs, monkeys, and even frogs and yet can apply his results on the human level. Finally, there are phenomena in nature which are of such a generalized kind that they are the same in all animals and even in all plants. Man, fish, insects, and plants seem to breath ...
... of his research with rabbits, guinea pigs, monkeys, and even frogs and yet can apply his results on the human level. Finally, there are phenomena in nature which are of such a generalized kind that they are the same in all animals and even in all plants. Man, fish, insects, and plants seem to breath ...
TIB_34 - Stored Product Insect and Engineering Research
... testing conditions produced a significantly greater mean in both sexes for Reps 1,3 and 4 (see Tables 5 and 7). These results imply that some factor was increasing the response to selection under crowded conditions. The most likely cause of this was either natural selection supplementing the artific ...
... testing conditions produced a significantly greater mean in both sexes for Reps 1,3 and 4 (see Tables 5 and 7). These results imply that some factor was increasing the response to selection under crowded conditions. The most likely cause of this was either natural selection supplementing the artific ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.