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Prefrontal Activation Deficits During Episodic Memory in
Prefrontal Activation Deficits During Episodic Memory in

... ALE produces convergence maps of brain activation by examining the probability that spatially smoothed activation foci from individual studies occur across multiple studies. This approach tests the null hypothesis that the location of activated foci is equal at every voxel against an alternative hyp ...
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i BASAL GANGLIA PATHWAYS: BEYOND THE CLOSED

... learned a great deal under his guidance and he has helped me grow both as a scientist and as a person. I would also like to thank the members of my dissertation committee: Rob Turner, Julie Fiez, Linda Rinaman and David Lewis for their time, interest, and feedback, and Okihide Hikosaka for accepting ...
Retrieval induces adaptive forgetting of competing memories via
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... visual cortical activity when a retrieval cue concurrently elicits multiple visual memories. These studies revealed that pattern classifiers have difficulty discriminating whether a retrieval cue is eliciting a memory of a face or an object when both types of content are associated with it, even whe ...
Low Quality
Low Quality

Lum, J.A.G., Conti-Ramsden, G., Page, D., and Ullman, M.T. (2012).
Lum, J.A.G., Conti-Ramsden, G., Page, D., and Ullman, M.T. (2012).

... Ullman and Pierpont, 2005). Learning in procedural memory is slower than in declarative memory; it proceeds gradually, as stimuli are repeated and skills practiced. However, once this knowledge has been acquired, skills can be executed rapidly. Although the neural bases of procedural memory are less ...
Stress, serotonin, and hippocampal neurogenesis
Stress, serotonin, and hippocampal neurogenesis

... (Akiskal et al., 1983). More recent theoretical focus has largely been on biological factors, including a wealth of information supporting stress as a causal factor in depression, largely concerning chronic stress-related HPA dysregulation and toxicity from excessive glucocorticoid release (Lupien e ...
Insights into Rapid Modulation of Neuroplasticity by Brain Estrogens
Insights into Rapid Modulation of Neuroplasticity by Brain Estrogens

Free recall and recognition in a network model of the... simulating effects of scopolamine on human memory function
Free recall and recognition in a network model of the... simulating effects of scopolamine on human memory function

... human memory function, we have developed a model of hippocampal episodic memory function which can be used to link these effects to specific parameters of cholinergic physiology. Modeling the hippocampus is appropriate because of the neuropsychological data showing that lesions of the hippocampus se ...
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... animals do present spontaneous locomotor behavior, which by definition is not influenced or directed by cognitive inputs from the telencephalon because it has been removed or disconnected [88]. In the sense of providing a certain level of endogenous activity (perhaps some form of ‘setpoint’), the hy ...
(2000). Cerebral hemisphere regulation of motivated behavior.
(2000). Cerebral hemisphere regulation of motivated behavior.

... animals do present spontaneous locomotor behavior, which by definition is not influenced or directed by cognitive inputs from the telencephalon because it has been removed or disconnected [88]. In the sense of providing a certain level of endogenous activity (perhaps some form of ‘setpoint’), the hy ...
Blockade of Central Cholinergic Receptors Impairs New Learning
Blockade of Central Cholinergic Receptors Impairs New Learning

... Stern, & Howard, 2003). These studies suggest that the effects of scopolamine may particularly affect the hippocampus and parahippocampal structures, as lesions of these structures cause a similar pattern of deficits (impaired recognition and recall of previously experienced events, with sparing of ...
Blockade of Central Cholinergic Receptors Impairs New Learning and
Blockade of Central Cholinergic Receptors Impairs New Learning and

... Stern, & Howard, 2003). These studies suggest that the effects of scopolamine may particularly affect the hippocampus and parahippocampal structures, as lesions of these structures cause a similar pattern of deficits (impaired recognition and recall of previously experienced events, with sparing of ...
Stop Using Introspection to Gather Data for the Design of... Modeling and Spatial Assistance
Stop Using Introspection to Gather Data for the Design of... Modeling and Spatial Assistance

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Aerobic Glycolysis in the Frontal Cortex Correlates with Memory

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... areas such as the parietal cortex including the retrosplenial cortex (which is part of the posterior cingulate cortex) that provide inputs via parahippocampal areas TF/TH to the hippocampus for its spatial (‘where’) functions in memory, which are described in Section 4. In a complementary way, the h ...
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The Olfactory–Limbic System and Multiple Chemical

... In addition some odorant nerve impulses, from the primary olfactory cortex, are further projected to deeper nuclei structures within the brain. These structures are referred to collectively as the secondary olfactory regions or secondary olfactory cortex. “Auditory and visual sensory information re ...
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Interactions between frontal cortex and basal ganglia in working

... 1986). The GPi and SNr circuits are functionally analogous (although they have different subcortical targets), so we consider them as one functional entity. Both the frontal cortex and the striatum also receive inputs from various areas of the posterior/sensory cortex. There are also other pathways ...
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Topographic Organization of Connections Between the Hypothalamus and

... *Correspondence to: Nancy Rempel-Clower, Department of Health Sciences, Boston University, 635 Commonwealth Ave., #425, Boston, MA ...
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Role of the basal ganglia in conditional associative learning
Role of the basal ganglia in conditional associative learning

... The arbitrary mapping of sensory information onto action forms an important element of the intelligent behavior of primates (also called conditional associative learning). The cortico-basal ganglia-thalamo-cortical loops are thought to play a key role in such behavior. The present research was under ...
Dangers of Ecstasy
Dangers of Ecstasy

... Parkinson’s-like conditiona and other disorders. Research has for some time suggested ecstasy injures the nerve endings in the brain which regulate mood and behaviour (serotonin). Results of a study released in September 2002 found, in animals, that taking several sequential doses of ecstasy can des ...
Neural substrates for conditioned taste aversion in the rat.
Neural substrates for conditioned taste aversion in the rat.

... being approximately 5 min. These findings suggest that LiC1 exerts its effect on the peripheral gastrointestinal organs and central nervous system with the latency of 5-10 min. Niijima and Yamamoto [105] have recently shown in anesthetized rats that direct application of 0.15 M LiCI onto the viscera ...
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Limbic system



The limbic system (or paleomammalian brain) is a complex set of brain structures located on both sides of the thalamus, right under the cerebrum. It is not a separate system but a collection of structures from the telencephalon, diencephalon, and mesencephalon. It includes the olfactory bulbs, hippocampus, amygdala, anterior thalamic nuclei, fornix, columns of fornix, mammillary body, septum pellucidum, habenular commissure, cingulate gyrus, parahippocampal gyrus, limbic cortex, and limbic midbrain areas.The limbic system supports a variety of functions including epinephrine flow, emotion, behavior, motivation, long-term memory, and olfaction. Emotional life is largely housed in the limbic system, and it has a great deal to do with the formation of memories.Although the term only originated in the 1940s, some neuroscientists, including Joseph LeDoux, have suggested that the concept of a functionally unified limbic system should be abandoned as obsolete because it is grounded mainly in historical concepts of brain anatomy that are no longer accepted as accurate.
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