Auxin and self-organization at the shoot apical
... as the organ primordia starts to bulge out, as a result of the increase in cell proliferation and growth of a small number of founder cells, another group of cells at the proximal end of the organ will slow down their growth rates. These cells will form the boundary between the organ and the SAM, pr ...
... as the organ primordia starts to bulge out, as a result of the increase in cell proliferation and growth of a small number of founder cells, another group of cells at the proximal end of the organ will slow down their growth rates. These cells will form the boundary between the organ and the SAM, pr ...
Role of Template Activating Factor-I as a
... separated by 10% SDS-PAGE and visualized with Coomassie Brilliant Blue staining. Lane M contains molecular size markers. (B) Formation of histone H1.1NCPs complexes was examined by nucleoprotein gel analyses. The 196 bp 5S rRNA gene fragments or NCPs (0.4 pmol of DNA) assembled on the same DNA with ...
... separated by 10% SDS-PAGE and visualized with Coomassie Brilliant Blue staining. Lane M contains molecular size markers. (B) Formation of histone H1.1NCPs complexes was examined by nucleoprotein gel analyses. The 196 bp 5S rRNA gene fragments or NCPs (0.4 pmol of DNA) assembled on the same DNA with ...
Tissue interactions in the developing chick diencephalon
... The observations described above have started to address the question of ZLI initiation; but we still lack a general picture of how this important signalling centre is established. Here, we have performed tissue culture experiments with chick forebrain explants to characterise the roles of various e ...
... The observations described above have started to address the question of ZLI initiation; but we still lack a general picture of how this important signalling centre is established. Here, we have performed tissue culture experiments with chick forebrain explants to characterise the roles of various e ...
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac
... Conflict of interest: The authors have declared that no conflict of interest exists. Citation for this article: J. Clin. Invest. 113:1130–1137 (2004). doi:10.1172/JCI200419846. ...
... Conflict of interest: The authors have declared that no conflict of interest exists. Citation for this article: J. Clin. Invest. 113:1130–1137 (2004). doi:10.1172/JCI200419846. ...
Functional Analysis of Class 1 RSL Genes in Caulonema and
... cytoskeleton and causes apical cells to swell without tip growth. These data indicate actin and microtubule cytoskeletons are required for caulonema differentiation in protonema development. Another gene, PpHXK1 (hexokinase of P. patens), regulates caulonema differentiation (Thelander et al., 2005). ...
... cytoskeleton and causes apical cells to swell without tip growth. These data indicate actin and microtubule cytoskeletons are required for caulonema differentiation in protonema development. Another gene, PpHXK1 (hexokinase of P. patens), regulates caulonema differentiation (Thelander et al., 2005). ...
Platelets Served with - The Journal of Immunology
... the induction of neutrophil extracellular trap (NET) formation (13, 19), a process that also was described to occur in other settings, including thrombosis, transfusion-related acute lung injury, storage of RBCs, and sickle cell disease (20–25). Interestingly, platelets also were shown to be involve ...
... the induction of neutrophil extracellular trap (NET) formation (13, 19), a process that also was described to occur in other settings, including thrombosis, transfusion-related acute lung injury, storage of RBCs, and sickle cell disease (20–25). Interestingly, platelets also were shown to be involve ...
Downloaded - Stem-cell and Brain Research Institute
... by the metabolic status of the organism. Indeed, glucose, one of the major food metabolites that exhibits a plasma diurnal rhythm, is a direct resetting signal in cultured cells by down-regulating per1 and per2 RNA levels (32). The levels of glucose-regulated hormones such as insulin or glucagon imm ...
... by the metabolic status of the organism. Indeed, glucose, one of the major food metabolites that exhibits a plasma diurnal rhythm, is a direct resetting signal in cultured cells by down-regulating per1 and per2 RNA levels (32). The levels of glucose-regulated hormones such as insulin or glucagon imm ...
View PDF - CiteSeerX
... The nucleotide sequence of the longest cDNA clone encodes a novel orphan nuclear receptor of 431 amino acids that we have designated PXR.1 (Figure 1A). We also isolated a second cDNA clone, termed PXR.2, that was identical to PXR.1 except for the deletion of a stretch of 123 nucleotides extending fr ...
... The nucleotide sequence of the longest cDNA clone encodes a novel orphan nuclear receptor of 431 amino acids that we have designated PXR.1 (Figure 1A). We also isolated a second cDNA clone, termed PXR.2, that was identical to PXR.1 except for the deletion of a stretch of 123 nucleotides extending fr ...
Theranostic Value of Multimers: Lessons Learned from Trimerization
... as a possible molecular agent for (radio)therapy and/or diagnosis of cancer by targeting NTS1 [6,7]. The shortest binding sequence of NT to NTS1 is the C-terminal fragment NT(8–13) with the amino acids Arg8 -Arg9 -Pro10 -Tyr11 -Ile12 -Leu13 -OH. This peptide sequence is rapidly degraded in vivo with ...
... as a possible molecular agent for (radio)therapy and/or diagnosis of cancer by targeting NTS1 [6,7]. The shortest binding sequence of NT to NTS1 is the C-terminal fragment NT(8–13) with the amino acids Arg8 -Arg9 -Pro10 -Tyr11 -Ile12 -Leu13 -OH. This peptide sequence is rapidly degraded in vivo with ...
patterning mechanisms controlling vertebrate limb development
... (TGF-β)/bone morphogenetic proteins (BMPs) and fibroblast growth factor (FGF) families of secreted factors, along with their transducers and modulators, appear to constitute a sort of ancient “genetic toolbox” that is used time and again in the embryo to build limbs, teeth, lungs, or kidneys. The fi ...
... (TGF-β)/bone morphogenetic proteins (BMPs) and fibroblast growth factor (FGF) families of secreted factors, along with their transducers and modulators, appear to constitute a sort of ancient “genetic toolbox” that is used time and again in the embryo to build limbs, teeth, lungs, or kidneys. The fi ...
Arachidonic Acid and Docosahexaenoic Acid Suppress Osteoclast Formation and Activity
... carbons and 2 double bonds that can be categorized into two principal families, namely: ω-3 LCPUFAs and ω-6 LCPUFAs [4]. The anti-inflammatory ω-3 LCPUFAs are derived from αlinolenic acid (ALA) while the pro-inflammatory ω-6 LCPUFAs are derived from linoleic acid (LA) [4, 8, 12, 13]. The human body ...
... carbons and 2 double bonds that can be categorized into two principal families, namely: ω-3 LCPUFAs and ω-6 LCPUFAs [4]. The anti-inflammatory ω-3 LCPUFAs are derived from αlinolenic acid (ALA) while the pro-inflammatory ω-6 LCPUFAs are derived from linoleic acid (LA) [4, 8, 12, 13]. The human body ...
Fear-of-intimacy mediated zinc transport controls the
... genomes. Recently, functional analyses measuring the phenotypic effects of zinc toxicity in the fly have demonstrated that most of the 17 putative zinc transporters of ...
... genomes. Recently, functional analyses measuring the phenotypic effects of zinc toxicity in the fly have demonstrated that most of the 17 putative zinc transporters of ...
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as
... secretory pathway gave rise to two models describing how ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become compete ...
... secretory pathway gave rise to two models describing how ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become compete ...
How the Environment Regulates Root Architecture in Dicots
... Root architecture is under the coordinated control of both genetic endogenous programs regulating growth and organogenesis and the action of abiotic and biotic environmental stimuli. The mature root system therefore results from the integration of intrinsic and extrinsic signals (Malamy, 2005). Thei ...
... Root architecture is under the coordinated control of both genetic endogenous programs regulating growth and organogenesis and the action of abiotic and biotic environmental stimuli. The mature root system therefore results from the integration of intrinsic and extrinsic signals (Malamy, 2005). Thei ...
Response to Bacteria Excess Production of IL-12 and IL
... (IBDs) including Crohn’s disease and ulcerative colitis remain unclear, pathogenic roles of the gut flora in initiation and perpetuation of intestinal inflammation have been proposed (7). Recently, it has become evident that abnormal innate immune responses to bacteria are responsible for the pathog ...
... (IBDs) including Crohn’s disease and ulcerative colitis remain unclear, pathogenic roles of the gut flora in initiation and perpetuation of intestinal inflammation have been proposed (7). Recently, it has become evident that abnormal innate immune responses to bacteria are responsible for the pathog ...
Amino acid regulation of mTORC1 Liron Bar-Peled
... mTORC1 responds to a diverse set of stimuli, including growth factors, oxygen availability, energy and amino acid levels in order to control essential anabolic and catabolic processes. Amino acids promote mTORC1 shuttling to the lysosomal surface, its site of activation. This translocation is mediat ...
... mTORC1 responds to a diverse set of stimuli, including growth factors, oxygen availability, energy and amino acid levels in order to control essential anabolic and catabolic processes. Amino acids promote mTORC1 shuttling to the lysosomal surface, its site of activation. This translocation is mediat ...
Mechanisms of transport through the Golgi complex
... Fig. 3. (A) Vesicle budding and fusion. Activation of a small G protein (such as Arf1 or Sar1) (red) by the exchange of GDP for GTP results in the recruitment of a coat complex (blue) to the membrane by the GTP-bound form of the G protein. Membrane curvature and sorting of cargo (yellow) into the fo ...
... Fig. 3. (A) Vesicle budding and fusion. Activation of a small G protein (such as Arf1 or Sar1) (red) by the exchange of GDP for GTP results in the recruitment of a coat complex (blue) to the membrane by the GTP-bound form of the G protein. Membrane curvature and sorting of cargo (yellow) into the fo ...
Brock_Charter_Christopher_2011
... in embryonic development, as well as organ homeostasis in the adult. In organisms such as adult axolotls and newts, RA is also important for regeneration of the CNS, limb, tail, and many other organ systems. RA mediates many of its effects in development and regeneration through nuclear receptors, k ...
... in embryonic development, as well as organ homeostasis in the adult. In organisms such as adult axolotls and newts, RA is also important for regeneration of the CNS, limb, tail, and many other organ systems. RA mediates many of its effects in development and regeneration through nuclear receptors, k ...
From filaments to function: The role of the plant actin cytoskeleton in
... trafficking, while actin-dependent, functions independently of microtubules. In a parallel study, Ribeiro et al. (2013) came to a similar conclusion, demonstrating that nucleoprotein trafficking is actin-dependent and microtubule-independent, while further showing that actin was not required for the a ...
... trafficking, while actin-dependent, functions independently of microtubules. In a parallel study, Ribeiro et al. (2013) came to a similar conclusion, demonstrating that nucleoprotein trafficking is actin-dependent and microtubule-independent, while further showing that actin was not required for the a ...
PDF
... in which the gene encoding a second homeoprotein, engrailed 1 (En1), has been deleted, dramatic loss of mdDA neurons and striatal innervation defects were observed, partially reminiscent of defects observed in Pitx3−/− mice. We then continue to reveal developmental crosstalk between En1 and Pitx3 th ...
... in which the gene encoding a second homeoprotein, engrailed 1 (En1), has been deleted, dramatic loss of mdDA neurons and striatal innervation defects were observed, partially reminiscent of defects observed in Pitx3−/− mice. We then continue to reveal developmental crosstalk between En1 and Pitx3 th ...