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Answers to the Study Guide for C12 Molecular Genetics Labeled
Answers to the Study Guide for C12 Molecular Genetics Labeled

... Deletion – when a base is taken out which also changes the reading frame. These two things are considered frameshift mutations and can be considered point mutations. 13. When a specific kind of protein is not continually used by a cell, the gene for that protein is usually repressible. 14. The lac o ...
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Central Dogma - Arkansas State University

... The Process of Transcription-2 • RNA synthesis continues (Elongation), only one DNA strand (template) is transcribed. • RNA nucleotides, complementary to bases on DNA strand, are connected to make mRNA • Termination: must be a stop sign, right? – In bacteria, hairpin loop followed by run of U’s in ...
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Polyadenylation



Polyadenylation is the addition of a poly(A) tail to a messenger RNA The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases. In eukaryotes, polyadenylation is part of the process that produces mature messenger RNA (mRNA) for translation. It, therefore, forms part of the larger process of gene expression.The process of polyadenylation begins as the transcription of a gene finishes, or terminates. The 3'-most segment of the newly made pre-mRNA is first cleaved off by a set of proteins; these proteins then synthesize the poly(A) tail at the RNA's 3' end. In some genes, these proteins may add a poly(A) tail at any one of several possible sites. Therefore, polyadenylation can produce more than one transcript from a single gene (alternative polyadenylation), similar to alternative splicing.The poly(A) tail is important for the nuclear export, translation, and stability of mRNA. The tail is shortened over time, and, when it is short enough, the mRNA is enzymatically degraded. However, in a few cell types, mRNAs with short poly(A) tails are stored for later activation by re-polyadenylation in the cytosol. In contrast, when polyadenylation occurs in bacteria, it promotes RNA degradation. This is also sometimes the case for eukaryotic non-coding RNAs.mRNA molecules in both prokaryotes and eukaryotes have polyadenylated 3'-ends, with the prokaryotic poly(A) tails generally shorter and less mRNA molecules polyadenylated.
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