LIMIX: genetic analysis of multiple traits
... have been proposed, first in the field of animal breeding [10] and, more recently, also in the context of GWAS [11, 12]. In genetics, the use of general-purpose mixed modeling tools is rare (e.g. ref. [13]), mainly because these lack the computational efficiency that is required to handle larger sam ...
... have been proposed, first in the field of animal breeding [10] and, more recently, also in the context of GWAS [11, 12]. In genetics, the use of general-purpose mixed modeling tools is rare (e.g. ref. [13]), mainly because these lack the computational efficiency that is required to handle larger sam ...
Implications of DNA replication for eukaryotic gene expression
... in a transcriptionally active state are now clear (Fig. 1; and Brown, 1984; Mitchell and Tjian, 1989). The initial direct binding of transcription factors to DNA is rapid, the sequestration of non-DNA binding factors is relatively slow. In vitro, the process of assembling a complete transcription co ...
... in a transcriptionally active state are now clear (Fig. 1; and Brown, 1984; Mitchell and Tjian, 1989). The initial direct binding of transcription factors to DNA is rapid, the sequestration of non-DNA binding factors is relatively slow. In vitro, the process of assembling a complete transcription co ...
Quantitative analysis of NOR expression in a B chromosome of the
... The mechanisms regulating the activation of ribosomal chromatin are less understood than those responsible for repression (Huang et al. 2006). Chromosome context appears to be important for NOR activity, as deduced from changes in the on/off activity status following chromosome rearrangements moving ...
... The mechanisms regulating the activation of ribosomal chromatin are less understood than those responsible for repression (Huang et al. 2006). Chromosome context appears to be important for NOR activity, as deduced from changes in the on/off activity status following chromosome rearrangements moving ...
Detection of 881 A→881 Mutation in Tyrosinase Gene and
... exclusively white (“albino” type) and they are often difficult to distinguish from one another by wool rabbit producers. Wool rabbits with special appearances as strainspecific markers are necessary for both rabbit breeders and producers. For this purpose we have developed a high wool producing rabb ...
... exclusively white (“albino” type) and they are often difficult to distinguish from one another by wool rabbit producers. Wool rabbits with special appearances as strainspecific markers are necessary for both rabbit breeders and producers. For this purpose we have developed a high wool producing rabb ...
Document
... was readily apparent in many of his crosses. For example, when he crossed two true-breeding plants for a trait such as height (i.e., tall versus dwarf), all the F1 plants were tall. This is inconsistent with blending. Perhaps more striking was the result obtained in the F 2 generation: 3/4 of the of ...
... was readily apparent in many of his crosses. For example, when he crossed two true-breeding plants for a trait such as height (i.e., tall versus dwarf), all the F1 plants were tall. This is inconsistent with blending. Perhaps more striking was the result obtained in the F 2 generation: 3/4 of the of ...
Brooker Chapter 6
... Therefore, the total number of wild-type phages is 11 X 106 or 11 million phages per milliliter Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
... Therefore, the total number of wild-type phages is 11 X 106 or 11 million phages per milliliter Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
Martina Šeruga Musić, Mladen Krajačić, Dijana Škorić
... For direct amplification of phytoplasma gene or pseudogene regions, three different primer pairs were used: 16R738f/16R1232r (GIBB et al., 1995), to amplify a part of 16S rRNA gene; fTufu/rTufu (SCHNEIDER et al., 1997), to amplify a part of tuf gene; and G35p/m (DAVIS et al., 1992), to amplify dnaB ...
... For direct amplification of phytoplasma gene or pseudogene regions, three different primer pairs were used: 16R738f/16R1232r (GIBB et al., 1995), to amplify a part of 16S rRNA gene; fTufu/rTufu (SCHNEIDER et al., 1997), to amplify a part of tuf gene; and G35p/m (DAVIS et al., 1992), to amplify dnaB ...
2-Oxoacid dehydrogenase multienzyme complexes
... adding guanidine thiocyanate (final concentration 20 mM) and 0n6 µl ethidium bromide (10 mg ml−") to 35 ml molten (cooled to 60 mC) agarose immediately prior to pouring into a casting tray pre-soaked for 2 h in 1 % SDS. After electrophoresis, the RNA was transferred to a nylon membrane by capillary- ...
... adding guanidine thiocyanate (final concentration 20 mM) and 0n6 µl ethidium bromide (10 mg ml−") to 35 ml molten (cooled to 60 mC) agarose immediately prior to pouring into a casting tray pre-soaked for 2 h in 1 % SDS. After electrophoresis, the RNA was transferred to a nylon membrane by capillary- ...
Cloning, sequence and in vitro transcription/translation analysis of a
... with the predicted ORFs. The 26.6-kDa protein produced by plasmids pMS1 and 3 corresponds to ORF E (predicted size 21.8 kDa). The 23.7-kDa protein made only by pMS1. 2, 5 and 6 corresponds to ORF A (1X.3 kDa). The 19.5, 12.5 and lo-kDa proteins made only by pMS1, 3, 5 and 7 arose from the $flrI to A ...
... with the predicted ORFs. The 26.6-kDa protein produced by plasmids pMS1 and 3 corresponds to ORF E (predicted size 21.8 kDa). The 23.7-kDa protein made only by pMS1. 2, 5 and 6 corresponds to ORF A (1X.3 kDa). The 19.5, 12.5 and lo-kDa proteins made only by pMS1, 3, 5 and 7 arose from the $flrI to A ...
Ryanodine Myopathies Without Central Cores-Clinical
... illustrate early-onset, progressive myopathies with predominant axial involvement. Histopathologic findings were abnormal but not specific for a diagnosis, particularly central core myopathy. Genetic testing helped broaden the range of phenotypes included in the RYR1-related myopathies. Our patients r ...
... illustrate early-onset, progressive myopathies with predominant axial involvement. Histopathologic findings were abnormal but not specific for a diagnosis, particularly central core myopathy. Genetic testing helped broaden the range of phenotypes included in the RYR1-related myopathies. Our patients r ...
Role of Bioinformatics Tools in Biological Research GPS
... probable intron and exon regions are compared to filter/remove wrong exons; NNSPLICE program is used to reassign splicing signal site positions ...
... probable intron and exon regions are compared to filter/remove wrong exons; NNSPLICE program is used to reassign splicing signal site positions ...
Phylogenetic Relationships Among Ascomycetes: Evidence from an
... Mims, and Blackwell 1996). Euascomycetes are both the most complex in morphology and the most diverse group in the Ascomycota. The major characters used to delineate the principal lineages of Euascomycetes are the morphology of the fruiting body (ascocarp) and the structure of the ascus (Nannfeldt 1 ...
... Mims, and Blackwell 1996). Euascomycetes are both the most complex in morphology and the most diverse group in the Ascomycota. The major characters used to delineate the principal lineages of Euascomycetes are the morphology of the fruiting body (ascocarp) and the structure of the ascus (Nannfeldt 1 ...
Dicot and monocot plants differ in retinoblastoma
... by the characterization of a partial maize cDNA clone (Grafi et al., 1996). The RBR genes from Zea mays, ZmRBR2a and ZmRBR2b (Ach et al., 1997), are partial cDNA sequences which may represent alternative splice variants of the ZmRBR2 gene. The degree of homology between the proteins encoded by these ...
... by the characterization of a partial maize cDNA clone (Grafi et al., 1996). The RBR genes from Zea mays, ZmRBR2a and ZmRBR2b (Ach et al., 1997), are partial cDNA sequences which may represent alternative splice variants of the ZmRBR2 gene. The degree of homology between the proteins encoded by these ...
Protein Synthesis ppt
... a. Enzyme binds to DNA, unzips it b. mRNA copy of gene made from DNA template *U replaces T in RNA ...
... a. Enzyme binds to DNA, unzips it b. mRNA copy of gene made from DNA template *U replaces T in RNA ...
Protein Synthesis
... a. Enzyme binds to DNA, unzips it b. mRNA copy of gene made from DNA template *U replaces T in RNA ...
... a. Enzyme binds to DNA, unzips it b. mRNA copy of gene made from DNA template *U replaces T in RNA ...
Silent polymorphisms in the RYR1 gene do not modify the
... As our patient is presenting a relatively benign clinical course, probably there is no significant association between her pathogenic mutation and the p.4752 T > T synonymous polymorphism, nor with any of the other silencing mutations later identified in her DNA, that could be acting as a modifier o ...
... As our patient is presenting a relatively benign clinical course, probably there is no significant association between her pathogenic mutation and the p.4752 T > T synonymous polymorphism, nor with any of the other silencing mutations later identified in her DNA, that could be acting as a modifier o ...
Lophotrochozoan relationships and parasites. A snap-shot
... parasites of echinoderms and their mosaic like character distribution puzzled researcher since the description of these worms. As annelids, myzostomid possess parapodia-like structures, chitinous chaetae, a ladder-like nervous system, a trochophore-like larva, and serially arranged nephridial organs ...
... parasites of echinoderms and their mosaic like character distribution puzzled researcher since the description of these worms. As annelids, myzostomid possess parapodia-like structures, chitinous chaetae, a ladder-like nervous system, a trochophore-like larva, and serially arranged nephridial organs ...
Predicting Cancer Susceptibility from Single-Nucleotide
... microarray data, the mRNA samples for cancer patients are taken from tumor tissue (e.g., from the colon), and the mRNA samples for healthy donors are taken from healthy tissue of the same type (e.g., colon again). SNP data, on the other hand, is not taken directly from tumor samples, but from any ti ...
... microarray data, the mRNA samples for cancer patients are taken from tumor tissue (e.g., from the colon), and the mRNA samples for healthy donors are taken from healthy tissue of the same type (e.g., colon again). SNP data, on the other hand, is not taken directly from tumor samples, but from any ti ...
Plant and Soil
... is that the assay for the presence of the marker is simpler than that of other methods. Most reporter genes used in ecological studies allow detection of the marked organism by eye, because the marker gene encodes an enzyme which gives rise to a coloured product following incubation with a histochem ...
... is that the assay for the presence of the marker is simpler than that of other methods. Most reporter genes used in ecological studies allow detection of the marked organism by eye, because the marker gene encodes an enzyme which gives rise to a coloured product following incubation with a histochem ...
Prostate Cancer Presentation
... Another way prostate cancer is found early is when the doctor does a digital rectal exam (DRE). Because the prostate gland lies just in front of the rectum, during the exam the doctor can feel if there are any bumps or hard places on the prostate. These might be cancer. ...
... Another way prostate cancer is found early is when the doctor does a digital rectal exam (DRE). Because the prostate gland lies just in front of the rectum, during the exam the doctor can feel if there are any bumps or hard places on the prostate. These might be cancer. ...
DNA sequence of the control region of phage D108: the N
... region of phage D108 is quite similar to that of phage Mu in spite of considerable divergence, both in the nucleotide sequence and in the amino acid sequences of the regulatory proteins of the two phages. The N—terminal amino acid sequences of the transposases of the two phages also share only limit ...
... region of phage D108 is quite similar to that of phage Mu in spite of considerable divergence, both in the nucleotide sequence and in the amino acid sequences of the regulatory proteins of the two phages. The N—terminal amino acid sequences of the transposases of the two phages also share only limit ...
Knowledge Discovery in Neuroblastoma
... The tool indicates most genomic areas that are known to have effect on neuroblastomas It also displays possible interactions between different genetic objects To combine knowledge from data sets, they do not necessarily have to contain the same patients anymore Finding interesting genetic areas is m ...
... The tool indicates most genomic areas that are known to have effect on neuroblastomas It also displays possible interactions between different genetic objects To combine knowledge from data sets, they do not necessarily have to contain the same patients anymore Finding interesting genetic areas is m ...
genetics - Gene In The Title
... At least in some cases, condition may not be mental or emotional http://www.msnbc.msn.com/id/35336470/ns/healthmore_health_news/ # there have been some ‘stutter’ stories in the past few weeks – here is another . . . from an unexpected source --- ...
... At least in some cases, condition may not be mental or emotional http://www.msnbc.msn.com/id/35336470/ns/healthmore_health_news/ # there have been some ‘stutter’ stories in the past few weeks – here is another . . . from an unexpected source --- ...
CHALLENGES AND PROMISE OF CULTURE AND GENES 1
... predisposed to be sensitive to some environmental inputs “for better or for worse” (Belsky, Bakermans-Kranenburg, & van IJzendoorn, 2007; Belsky et al., 2009; Obradović & Boyce, 2009). For instance, people with certain genotypes of a susceptibility gene may suffer through negative outcomes in one en ...
... predisposed to be sensitive to some environmental inputs “for better or for worse” (Belsky, Bakermans-Kranenburg, & van IJzendoorn, 2007; Belsky et al., 2009; Obradović & Boyce, 2009). For instance, people with certain genotypes of a susceptibility gene may suffer through negative outcomes in one en ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.