Novel cryptic chromosomal rearrangements in childhood acute
... as 22% of T-ALL patients. HOX11L2, an orphan homeobox gene located close to the chromosome 5 breakpoints was found to be transcriptionally activated as a result of this translocation.6 The t(7;11) also involves distal chromosome arm ends and cannot be detected upon banding analysis only, and thus ca ...
... as 22% of T-ALL patients. HOX11L2, an orphan homeobox gene located close to the chromosome 5 breakpoints was found to be transcriptionally activated as a result of this translocation.6 The t(7;11) also involves distal chromosome arm ends and cannot be detected upon banding analysis only, and thus ca ...
CHALLENGES AND PROMISE OF CULTURE AND GENES 1
... predisposed to be sensitive to some environmental inputs “for better or for worse” (Belsky, Bakermans-Kranenburg, & van IJzendoorn, 2007; Belsky et al., 2009; Obradović & Boyce, 2009). For instance, people with certain genotypes of a susceptibility gene may suffer through negative outcomes in one en ...
... predisposed to be sensitive to some environmental inputs “for better or for worse” (Belsky, Bakermans-Kranenburg, & van IJzendoorn, 2007; Belsky et al., 2009; Obradović & Boyce, 2009). For instance, people with certain genotypes of a susceptibility gene may suffer through negative outcomes in one en ...
Nucleotide Sequence Preservation of Human
... mutations in human leukemic cells. With the exception of 3 clones, we found no evidence of mtDNA nucleotide sequence divergence in 387 independently isolated mtDNA clones isolated from the leukemic cells of 4 patients. The small amount of nucleotide sequence divergence identified in the mtDNAs of 4 ...
... mutations in human leukemic cells. With the exception of 3 clones, we found no evidence of mtDNA nucleotide sequence divergence in 387 independently isolated mtDNA clones isolated from the leukemic cells of 4 patients. The small amount of nucleotide sequence divergence identified in the mtDNAs of 4 ...
Repeated Sequences in CASPASE-5 and FANCD2 but not NF1 Are
... (Table 2). The regions of interest were amplified with fluorescent primers and the length of the fluorescent products was used to define a genotype. The approach was validated using the A10 repeat of CASPASE-5, which is a known target for mutation in MMR-deficient cells. Examples of genotyping and d ...
... (Table 2). The regions of interest were amplified with fluorescent primers and the length of the fluorescent products was used to define a genotype. The approach was validated using the A10 repeat of CASPASE-5, which is a known target for mutation in MMR-deficient cells. Examples of genotyping and d ...
Presentation Slides
... • Relational learning is an object oriented approach to representation and learning that clearly distinguishes between entities (e.g., objects), relationships and their respective attributes and represents an area of growing interest in machine learning • Learned dependencies encode probabilistic co ...
... • Relational learning is an object oriented approach to representation and learning that clearly distinguishes between entities (e.g., objects), relationships and their respective attributes and represents an area of growing interest in machine learning • Learned dependencies encode probabilistic co ...
Migration and mutation
... fˆP (1 − P ). But at first glance they seem unrelated. One refers to the variance of gene frequencies between replicate populations and the other to the expected level of autozygosity within a population. The formal relationship between the two can be seen by considering the expected frequencies of ...
... fˆP (1 − P ). But at first glance they seem unrelated. One refers to the variance of gene frequencies between replicate populations and the other to the expected level of autozygosity within a population. The formal relationship between the two can be seen by considering the expected frequencies of ...
Chapter 5. Genetic Interactions and Pathways
... the purpose of these analyses is to see what happens when the two different alleles are in the same organism. If strain backgrounds differ, mutations in additional genes may contribute to differences in the phenotypes observed in these analyses. Dissecting the contribution of genetic heterogeneity w ...
... the purpose of these analyses is to see what happens when the two different alleles are in the same organism. If strain backgrounds differ, mutations in additional genes may contribute to differences in the phenotypes observed in these analyses. Dissecting the contribution of genetic heterogeneity w ...
The MetaCyc database of metabolic pathways
... (PGDBs), each containing the full genome and predicted metabolic network of one organism, including metabolites, enzymes, reactions, metabolic pathways, predicted operons, transport systems, and pathway-hole fillers. The BioCyc website offers a variety of tools for querying and analyzing PGDBs, incl ...
... (PGDBs), each containing the full genome and predicted metabolic network of one organism, including metabolites, enzymes, reactions, metabolic pathways, predicted operons, transport systems, and pathway-hole fillers. The BioCyc website offers a variety of tools for querying and analyzing PGDBs, incl ...
PDF
... We first performed a detailed analysis of H19 expression in both transgenic lines. Tg24 and YZ8 YAC mice were analyzed on the H19Δ3 background, which meant that any resulting H19 expression was of transgenic origin only. These two genotypes were compared with wild-type mice. Northern analysis was pe ...
... We first performed a detailed analysis of H19 expression in both transgenic lines. Tg24 and YZ8 YAC mice were analyzed on the H19Δ3 background, which meant that any resulting H19 expression was of transgenic origin only. These two genotypes were compared with wild-type mice. Northern analysis was pe ...
The Bacillus subtilis clpC operon encodes DNA
... survive unfavourable environmental conditions is crucial. In order to respond to stressful situations or starvation, the cell has developed an adaptive network including stress responses and post-exponential-phase phenomena such as the development of genetic competence, motility, synthesis of degrad ...
... survive unfavourable environmental conditions is crucial. In order to respond to stressful situations or starvation, the cell has developed an adaptive network including stress responses and post-exponential-phase phenomena such as the development of genetic competence, motility, synthesis of degrad ...
Molecular Genetics
... in that cell and in future daughter cells. The cell may die or simply not perform its normal function. These mutations are not passed on to the next generation. When mutations occur in sex cells, they will be present in every cell of the offspring. ...
... in that cell and in future daughter cells. The cell may die or simply not perform its normal function. These mutations are not passed on to the next generation. When mutations occur in sex cells, they will be present in every cell of the offspring. ...
CERN EXT-2004-059,Health Physics and Radiation Effects
... Jacob and Monod (1961) have shown, that in E. Coli the "regulator gene" and three "structural genes" concerned with lactose metabolism lie near one another in the same region of the chromosome. Another special region near one of the structural genes has the capacity of responding to the regulator ge ...
... Jacob and Monod (1961) have shown, that in E. Coli the "regulator gene" and three "structural genes" concerned with lactose metabolism lie near one another in the same region of the chromosome. Another special region near one of the structural genes has the capacity of responding to the regulator ge ...
Genetic polymorphisms of vein wall remodeling in chronic venous
... pathogenesis remains unclear, although various studies have suggested a potential genetic contribution.4 This condition may be primary (abnormalities of vein walls or valves) or secondary (after venous thrombosis; ie, PTS). Risk factors include age, female gender, pregnancy, family history, obesity, ...
... pathogenesis remains unclear, although various studies have suggested a potential genetic contribution.4 This condition may be primary (abnormalities of vein walls or valves) or secondary (after venous thrombosis; ie, PTS). Risk factors include age, female gender, pregnancy, family history, obesity, ...
Slide 1
... in that cell and in future daughter cells. The cell may die or simply not perform its normal function. These mutations are not passed on to the next generation. When mutations occur in sex cells, they will be present in every cell of the offspring. ...
... in that cell and in future daughter cells. The cell may die or simply not perform its normal function. These mutations are not passed on to the next generation. When mutations occur in sex cells, they will be present in every cell of the offspring. ...
Matthew Kwong - GEP Community Server
... The final exon in contig 10 (exon 4 for isoforms ey-PA, ey-PC and exon 5 for isoform eyPD) likely does not represent the end of the gene since ey has eleven unique exons with either eight or nine being expressed (depending on the isoform). Thus, the ey gene likely extends past contig 10. The final e ...
... The final exon in contig 10 (exon 4 for isoforms ey-PA, ey-PC and exon 5 for isoform eyPD) likely does not represent the end of the gene since ey has eleven unique exons with either eight or nine being expressed (depending on the isoform). Thus, the ey gene likely extends past contig 10. The final e ...
Direct Sequence Analysis of the 14q+ and 18q
... Analysis of mbr junctions in bcl-2. DNA was prepared from a series of 11 follicular lymphoma samples. Enzymatic amplification using primers BC1 and JH1 was performed on each DNA sample, and electrophoresis showed specific products from 7 of 11 samples (data not shown). Under the conditions of amplif ...
... Analysis of mbr junctions in bcl-2. DNA was prepared from a series of 11 follicular lymphoma samples. Enzymatic amplification using primers BC1 and JH1 was performed on each DNA sample, and electrophoresis showed specific products from 7 of 11 samples (data not shown). Under the conditions of amplif ...
A visual tool to explore phylogenetic trees Tamara Tershakovec
... A branching treelike diagram used to illustrate evolutionary (phylogenetic) relationships among organisms. Each node, or point of divergence, has two branching lines of descendance, indicating evolutionary divergence ...
... A branching treelike diagram used to illustrate evolutionary (phylogenetic) relationships among organisms. Each node, or point of divergence, has two branching lines of descendance, indicating evolutionary divergence ...
Genetics - Department of Plant Biology
... genetic variety than mutation alone. As described in Chapter 12, the gametes of a plant-sperm and egg--are haploid, each having only one chromosome of each type. Their union forms a new single cell, the zygote, which has two sets of chromosomes. Thus, the zygote, and the plant that develops from it, ...
... genetic variety than mutation alone. As described in Chapter 12, the gametes of a plant-sperm and egg--are haploid, each having only one chromosome of each type. Their union forms a new single cell, the zygote, which has two sets of chromosomes. Thus, the zygote, and the plant that develops from it, ...
Q4 Lab Biology Final Exam Study Guide
... 40. Describe the 4 phases of mitosis: a. Prophase b. Metaphase c. Anaphase d. Telophase 41. Explain the purpose of meiosis. 42. Describe the phases of meiosis: 43. Explain the difference between the haploid and diploid number of chromosomes in a cell. What type of cells would be associated with eac ...
... 40. Describe the 4 phases of mitosis: a. Prophase b. Metaphase c. Anaphase d. Telophase 41. Explain the purpose of meiosis. 42. Describe the phases of meiosis: 43. Explain the difference between the haploid and diploid number of chromosomes in a cell. What type of cells would be associated with eac ...
PDF
... regulatory core protein to exert ‘organizer‘ activity in Xenopus embryos. Its ancient paralog, lhx3 (lim3), is expressed around the blastopore in amphioxus and ascidian, but not vertebrate, gastrulae. These two genes are thus implicated in organizer evolution, and we addressed the evolutionary origi ...
... regulatory core protein to exert ‘organizer‘ activity in Xenopus embryos. Its ancient paralog, lhx3 (lim3), is expressed around the blastopore in amphioxus and ascidian, but not vertebrate, gastrulae. These two genes are thus implicated in organizer evolution, and we addressed the evolutionary origi ...
First report of a tetracycline-inducible gene
... transformant in which the plasmid had integrated into the chromosome and hence was expected to be stably maintained even in the absence of selection pressure. Individual transformants were grown in the presence of tetracycline and subcultured for five passages in the presence of gentamicin before su ...
... transformant in which the plasmid had integrated into the chromosome and hence was expected to be stably maintained even in the absence of selection pressure. Individual transformants were grown in the presence of tetracycline and subcultured for five passages in the presence of gentamicin before su ...
genomic flux: genome evolution by gene loss and
... than those of bacteria. For such species, the estimate is made that a new mutation with no effect on fitness has a probability of 1IN of drifting to fixation, with N being the population size. Therefore, in the absence of selection, every neutral allele in the gene pool has an equal probability of d ...
... than those of bacteria. For such species, the estimate is made that a new mutation with no effect on fitness has a probability of 1IN of drifting to fixation, with N being the population size. Therefore, in the absence of selection, every neutral allele in the gene pool has an equal probability of d ...
Biotechnology
... 1. Which of the following are important features for transcription? a. promoter b. RNA polymerase c. 5′and 3′UTRs d. ORF e. all of the above 2. For which of the following nitrogenous bases does DNA substitute thymine? a. uracil b. adenine c. guanine d. cytosine e. inosine 3. Which of the following ...
... 1. Which of the following are important features for transcription? a. promoter b. RNA polymerase c. 5′and 3′UTRs d. ORF e. all of the above 2. For which of the following nitrogenous bases does DNA substitute thymine? a. uracil b. adenine c. guanine d. cytosine e. inosine 3. Which of the following ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.