Drugs and the Synapse
... • The portion inside the neuron activates a Gprotein –one that is coupled to guanosine triphosphate (GTP), an energy storing molecule. • G-protein increases the concentration of a “second-messenger”. • The second messenger communicates to areas within the cell. – May open or close ion channels, alte ...
... • The portion inside the neuron activates a Gprotein –one that is coupled to guanosine triphosphate (GTP), an energy storing molecule. • G-protein increases the concentration of a “second-messenger”. • The second messenger communicates to areas within the cell. – May open or close ion channels, alte ...
Identification of Plasmodium falciparum var1CSA
... Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA). CSA binding infected erythrocytes also bind Ig ...
... Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA). CSA binding infected erythrocytes also bind Ig ...
E. coli
... • Fimbriae in many G-ve bacteria • Shorter, straighter, and thinner than flagella • Few to several hundred • For attachment rather than for motility • Pili are used to transfer DNA from one cell to another (sex pili) • One or two per cell Copyright © 2004 Pearson Education, Inc., publishing as Benj ...
... • Fimbriae in many G-ve bacteria • Shorter, straighter, and thinner than flagella • Few to several hundred • For attachment rather than for motility • Pili are used to transfer DNA from one cell to another (sex pili) • One or two per cell Copyright © 2004 Pearson Education, Inc., publishing as Benj ...
A Novel Recombinant Plasma Membrane
... (P2X7R). Both cell types release large amounts of ATP (100 –200 M) in response to P2X7R activation. This novel approach unveils a hitherto unsuspected nonlytic pathway for the release of large amounts of ATP that might contribute to spreading activation and recruitment of immune cells at inflammato ...
... (P2X7R). Both cell types release large amounts of ATP (100 –200 M) in response to P2X7R activation. This novel approach unveils a hitherto unsuspected nonlytic pathway for the release of large amounts of ATP that might contribute to spreading activation and recruitment of immune cells at inflammato ...
INTRODUCTION
... fragmentation of the mitochondrial reticulum there is one nucleoid per minimal sized fragment. The crystal structure of TFAM shows that it bends mtDNA in a sharp U-turn. Several other proteins are a part, often transiently, of the nucleoid including prohibitin, single-stranded DNA-binding protein, m ...
... fragmentation of the mitochondrial reticulum there is one nucleoid per minimal sized fragment. The crystal structure of TFAM shows that it bends mtDNA in a sharp U-turn. Several other proteins are a part, often transiently, of the nucleoid including prohibitin, single-stranded DNA-binding protein, m ...
Histoarchitecture and scanning electron microscopic studies of the
... special interest because they form part of the olfactory transduction mechanism, are stimulated by odour-bearing substances, and also enable the fish to detect food. The microvillous receptor cells might form a different olfactory transduction mechanism for pheromones or amino acids. Hansen et al. ( ...
... special interest because they form part of the olfactory transduction mechanism, are stimulated by odour-bearing substances, and also enable the fish to detect food. The microvillous receptor cells might form a different olfactory transduction mechanism for pheromones or amino acids. Hansen et al. ( ...
Gene Section TGFB1 (transforming growth factor, beta 1)
... 1998), TRAP-1 (Charng et al., 1998), FKBP12 (Wang et al., 1994) and Ras/Raf/ERK (Matsuzaki, 2011). In the SMAD-dependent pathways, the receptor complex (or directly the type I receptor) phosphorylates receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5 and SMAD8) which can now bind the coo ...
... 1998), TRAP-1 (Charng et al., 1998), FKBP12 (Wang et al., 1994) and Ras/Raf/ERK (Matsuzaki, 2011). In the SMAD-dependent pathways, the receptor complex (or directly the type I receptor) phosphorylates receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5 and SMAD8) which can now bind the coo ...
Investigation of Iron-Sulfur Protein Maturation in Eukaryotes
... machinery is responsible for the de novo synthesis of Fe-S clusters and the insertion of these cofactors into mitochondrial Fe-S apo-proteins. This system is also involved in the maturation of Fe-S proteins that are located outside the mitochondria in the cytosol or nucleus. A mitochondrial export s ...
... machinery is responsible for the de novo synthesis of Fe-S clusters and the insertion of these cofactors into mitochondrial Fe-S apo-proteins. This system is also involved in the maturation of Fe-S proteins that are located outside the mitochondria in the cytosol or nucleus. A mitochondrial export s ...
PDF with detailed project information
... http://www.mpimp-golm.mpg.de/2070554/translational-regulation-in-plants Research in the Haydon and Zoschke Labs The Haydon lab is interested in plant cell signalling, with a particular interest in integration of external and internal signals and their impact on plant physiology. For example, our res ...
... http://www.mpimp-golm.mpg.de/2070554/translational-regulation-in-plants Research in the Haydon and Zoschke Labs The Haydon lab is interested in plant cell signalling, with a particular interest in integration of external and internal signals and their impact on plant physiology. For example, our res ...
In vitro phosphorylation of the movement protein of tomato mosaic
... tabacum and tobacco suspension culture cells (BY-2) in the presence of [γ-32P]ATP. Phosphorylation occurred even after washing the beads with a detergent-containing buffer, indicating that the recombinant MP formed a stable complex with some protein kinase(s) during incubation with the cell extract. ...
... tabacum and tobacco suspension culture cells (BY-2) in the presence of [γ-32P]ATP. Phosphorylation occurred even after washing the beads with a detergent-containing buffer, indicating that the recombinant MP formed a stable complex with some protein kinase(s) during incubation with the cell extract. ...
Block 3 - Miss Organelle Pageant
... Birthday: March 8, 2012 Hometown: Plant Cells Relationship Status: Single…It’s complicated with Stroma ...
... Birthday: March 8, 2012 Hometown: Plant Cells Relationship Status: Single…It’s complicated with Stroma ...
how death shapes life during development
... abnormalities and reduced cell death in the nervous system, which results in brain overgrowth97,98. Furthermore, animals with mutations in caspase-3, caspase-8 and caspase-9 die during either embryonic or perinatal development. Mice with caspase-8 mutations die during embryogenesis with abnormalitie ...
... abnormalities and reduced cell death in the nervous system, which results in brain overgrowth97,98. Furthermore, animals with mutations in caspase-3, caspase-8 and caspase-9 die during either embryonic or perinatal development. Mice with caspase-8 mutations die during embryogenesis with abnormalitie ...
Reconstitution of Outer Membrane Protein Assembly from Purified
... b-barrel membrane proteins in Gram-negative bacteria, mitochondria, and chloroplasts are assembled by highly conserved multi-protein complexes. The mechanism by which these molecular machines fold and insert their substrates is poorly understood. It has not been possible to dissect the folding and i ...
... b-barrel membrane proteins in Gram-negative bacteria, mitochondria, and chloroplasts are assembled by highly conserved multi-protein complexes. The mechanism by which these molecular machines fold and insert their substrates is poorly understood. It has not been possible to dissect the folding and i ...
HRT Gene Function Requires Interaction between a NAC Protein
... First, most of the characterized R gene products share structural motifs. Among them, nucleotide binding sites (NBS) and leucine-rich repeats (LRR) have been most commonly described. TIP lacks both NBS and LRR motifs. However, the product of HRT, a newly characterized gene involved in the TCV resist ...
... First, most of the characterized R gene products share structural motifs. Among them, nucleotide binding sites (NBS) and leucine-rich repeats (LRR) have been most commonly described. TIP lacks both NBS and LRR motifs. However, the product of HRT, a newly characterized gene involved in the TCV resist ...
The C-terminal end of R-Ras contains a focal adhesion targeting
... as the proline-rich sequence in the hypervariable region of RRas, are essential for this activation process (Oertli et al., 2000; Wang et al., 2000). The proline-rich region has been shown to bind the adaptor protein Nck, which is known to interact with proteins accumulating in focal adhesions (Wang ...
... as the proline-rich sequence in the hypervariable region of RRas, are essential for this activation process (Oertli et al., 2000; Wang et al., 2000). The proline-rich region has been shown to bind the adaptor protein Nck, which is known to interact with proteins accumulating in focal adhesions (Wang ...
Role of Inhibitory Neurotransmitter Interactions in the Pathogenesis
... and endorphins have both been studied for their role as inhibitory neurotransmitters in relation to neonatal respiratory control,1 the focus of this review will be on gamma aminobutyric acid (GABA), adenosine, and their potential interaction as the major modulators of respiratory neural output in ea ...
... and endorphins have both been studied for their role as inhibitory neurotransmitters in relation to neonatal respiratory control,1 the focus of this review will be on gamma aminobutyric acid (GABA), adenosine, and their potential interaction as the major modulators of respiratory neural output in ea ...
Identification and Characterization of Genes Required for Cell
... the colony (18). Cytoplasm and organelles flow freely through the fused fusion hyphae. Based on morphological criteria, the process of hyphal cell fusion can be roughly divided into three stages (17), beginning with a stage in which the tips of two fusion hyphae grow toward each other. Chemotrophic ...
... the colony (18). Cytoplasm and organelles flow freely through the fused fusion hyphae. Based on morphological criteria, the process of hyphal cell fusion can be roughly divided into three stages (17), beginning with a stage in which the tips of two fusion hyphae grow toward each other. Chemotrophic ...
Control of cytoplasmic pH under anoxic
... Riccia (Felle and Bertl, 1986ft) using cyanide, by Roberts et al. (1984a, b) and Fox et al. (1995) in maize roots replacing oxygen for nitrogen. Therefore, it appears that for a variety of organisms this pH shift is common, reflecting the difference in cytoplasmic pH from aerobic to anaerobic metabo ...
... Riccia (Felle and Bertl, 1986ft) using cyanide, by Roberts et al. (1984a, b) and Fox et al. (1995) in maize roots replacing oxygen for nitrogen. Therefore, it appears that for a variety of organisms this pH shift is common, reflecting the difference in cytoplasmic pH from aerobic to anaerobic metabo ...
Function of Conserved Tryptophans in the Aspergillus niger
... binding site and any large structural change in this region associated with addition of ligand is unlikely. The titration results for the W543 H1 peak, on the other hand, are quite different. This resonance shows no change in chemical shift at any ligand concentration. This is consistent with the W ...
... binding site and any large structural change in this region associated with addition of ligand is unlikely. The titration results for the W543 H1 peak, on the other hand, are quite different. This resonance shows no change in chemical shift at any ligand concentration. This is consistent with the W ...
Potentiometric measurement of intracellular redox activity.
... pathways in cells involve redox reactions and specific redox couples that cycle between oxidized and reduced states. The concentrations of the redox couples help regulate the flow of metabolites through these pathways.1,2 Moreover, recent evidence suggests that the concentrations of specific redox c ...
... pathways in cells involve redox reactions and specific redox couples that cycle between oxidized and reduced states. The concentrations of the redox couples help regulate the flow of metabolites through these pathways.1,2 Moreover, recent evidence suggests that the concentrations of specific redox c ...
Mitochondrial involvement in tracheary element
... mammals, but no canonical forms are found in fungi, protists, and plants. A current hypothesis is that cytochrome c binds to the scaffold complex called apoptotic protease activation factor 1 (Apaf1), and causes recruitment of procaspase-9 which transactivates due to close proximity.7 Clearly, cytoc ...
... mammals, but no canonical forms are found in fungi, protists, and plants. A current hypothesis is that cytochrome c binds to the scaffold complex called apoptotic protease activation factor 1 (Apaf1), and causes recruitment of procaspase-9 which transactivates due to close proximity.7 Clearly, cytoc ...
Full-Text PDF
... proteins frequently involves discrete targeting motifs, short sequences present in cytoplasmic domains of such membrane proteins that mediate their inclusion into transport vesicles via direct or indirect interactions with the vesicle forming coat machinery. The best-understood class of cellular tar ...
... proteins frequently involves discrete targeting motifs, short sequences present in cytoplasmic domains of such membrane proteins that mediate their inclusion into transport vesicles via direct or indirect interactions with the vesicle forming coat machinery. The best-understood class of cellular tar ...
Group B Sox Genes That Contribute to Specification of the
... seen in cells at the pole facing the blastocoel (arrowhead). B, C A late gastrula at 43 hr of development, B lateral view and C frontal view. Weak signal is seen in the entire ectoderm while strong signal is evident the stomodeum region (arrowhead). D, E A 4-day-old tornaria larva, D frontal view an ...
... seen in cells at the pole facing the blastocoel (arrowhead). B, C A late gastrula at 43 hr of development, B lateral view and C frontal view. Weak signal is seen in the entire ectoderm while strong signal is evident the stomodeum region (arrowhead). D, E A 4-day-old tornaria larva, D frontal view an ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.