5-Fluorouracil encapsulated alginate beads for the treatment of
... Received 13 December 2001; received in revised form 20 December 2001; accepted 25 December 2001 ...
... Received 13 December 2001; received in revised form 20 December 2001; accepted 25 December 2001 ...
G1 Phase-Dependent Expression of Bcl
... PBS and reculture in the growth medium. At each time point, onethird of the cells were harvested for Western blotting assay, onethird for cell cycle analysis, and one-third were treated for 3 or 24 h with either etoposide (50 M/ml), cisplatin (20 M/ml), or staurosporin (1 M/ml). After each treatm ...
... PBS and reculture in the growth medium. At each time point, onethird of the cells were harvested for Western blotting assay, onethird for cell cycle analysis, and one-third were treated for 3 or 24 h with either etoposide (50 M/ml), cisplatin (20 M/ml), or staurosporin (1 M/ml). After each treatm ...
PrimeFlow™ RNA Assay Technology Validation Paper
... cryopreserved and analyzed one week later (Experiment 2) for the expression of IFNγ mRNA and protein. Samples were surface stained with Anti-Human CD8a PE-eFluor® 610 (cat. no. 61-0088) and followed by hybridization of human IFNγ Alexa Fluor® 750 ...
... cryopreserved and analyzed one week later (Experiment 2) for the expression of IFNγ mRNA and protein. Samples were surface stained with Anti-Human CD8a PE-eFluor® 610 (cat. no. 61-0088) and followed by hybridization of human IFNγ Alexa Fluor® 750 ...
1 Distinct FAK activities determine progenitor
... and other receptors to regulate diverse cellular functions via kinase –dependent and –independent mechanisms (13-15), has been implicated in the development and progression of breast and other cancers (16-22). Further, we found that loss of FAK decreased the content of mammary cancer stem cells (MaC ...
... and other receptors to regulate diverse cellular functions via kinase –dependent and –independent mechanisms (13-15), has been implicated in the development and progression of breast and other cancers (16-22). Further, we found that loss of FAK decreased the content of mammary cancer stem cells (MaC ...
Thesis - KI Open Archive
... physicians were able, for the first time, to easily obtain large reductions in plasma cholesterol. Lovastatin at its maximal recommended dose of 80 mg daily produced a mean reduction in LDL cholesterol (low density lipoprotein cholesterol, or the “bad cholesterol”1) of 40 %, a far greater reduction ...
... physicians were able, for the first time, to easily obtain large reductions in plasma cholesterol. Lovastatin at its maximal recommended dose of 80 mg daily produced a mean reduction in LDL cholesterol (low density lipoprotein cholesterol, or the “bad cholesterol”1) of 40 %, a far greater reduction ...
Circular of Information for the Use of Cellular Therapy Products
... This Circular is prepared by the Circular of Information for Cellular Therapy Products Task Force consisting of representatives from AABB, American Association of Tissue Banks (AATB), American Red Cross (ARC), American Society for Blood and Marrow Transplantation (ASBMT), American Society for Aphere ...
... This Circular is prepared by the Circular of Information for Cellular Therapy Products Task Force consisting of representatives from AABB, American Association of Tissue Banks (AATB), American Red Cross (ARC), American Society for Blood and Marrow Transplantation (ASBMT), American Society for Aphere ...
NUtRItION ANd IMMUNIty IN MAN
... 1.2 Major cells of the immune system ...................................................................................................................................... 4 1.3 The immune system of the gut .......................................................................................... ...
... 1.2 Major cells of the immune system ...................................................................................................................................... 4 1.3 The immune system of the gut .......................................................................................... ...
Controlled analysis of nanoparticle charge on mucosal and systemic
... charge. By using the same initial batch for positively and negatively charged NPs, we were able to control for all other NP characteristics (size, shape, composition) and isolate charge as the single variable in these studies. A model antigen, ovalbumin (OVA), was covalently bound through an amide b ...
... charge. By using the same initial batch for positively and negatively charged NPs, we were able to control for all other NP characteristics (size, shape, composition) and isolate charge as the single variable in these studies. A model antigen, ovalbumin (OVA), was covalently bound through an amide b ...
Metabolic allometric scaling model. Combining cellular
... organisms' mass is considered as one of the most important. Simple relationships between the mass of organisms and their metabolic rates were empirically discovered a while ago. Such dependence is described by a power function, whose exponent is called allometric scaling coefficient. With the increa ...
... organisms' mass is considered as one of the most important. Simple relationships between the mass of organisms and their metabolic rates were empirically discovered a while ago. Such dependence is described by a power function, whose exponent is called allometric scaling coefficient. With the increa ...
Cyclin synthesis and degradation and the embryonic cell cycle
... required for the exit from meiosis. To address these issues, we turned to in vitro cell cycle extracts of frog eggs that were prepared by an adaptation of the method pioneered by Lohka and Masui (1983). These cell cycle extracts are capable of several cell cycles that proceed at rates similar to tho ...
... required for the exit from meiosis. To address these issues, we turned to in vitro cell cycle extracts of frog eggs that were prepared by an adaptation of the method pioneered by Lohka and Masui (1983). These cell cycle extracts are capable of several cell cycles that proceed at rates similar to tho ...
Chapter Five - Building a Fly Eye: Terminal
... Doroquez and Rebay, 2006; also see Chapter 4). The R8 cell arises first, followed by pairwise recruitment of R2/5, R3/4, and R1/6, and ending with R7 recruitment. Next, four nonneuronal CCs (also known as Semper cells) are recruited, and these cells are the last to be added during larval development ...
... Doroquez and Rebay, 2006; also see Chapter 4). The R8 cell arises first, followed by pairwise recruitment of R2/5, R3/4, and R1/6, and ending with R7 recruitment. Next, four nonneuronal CCs (also known as Semper cells) are recruited, and these cells are the last to be added during larval development ...
Development of intelligent vehicles for co- delivery of
... Presently breast cancer arises as one of the most prevalent malignancy in women worldwide, contributing for high rates of mortality and morbidity in several million patients. Currently there is still no available cure for this disease and to further aggravate this scenario the existing treatments su ...
... Presently breast cancer arises as one of the most prevalent malignancy in women worldwide, contributing for high rates of mortality and morbidity in several million patients. Currently there is still no available cure for this disease and to further aggravate this scenario the existing treatments su ...
Enumeration of soil bacteria with the green fluorescent
... intensities then microorganisms. In image analysis it has proved difficult to morphologically distinguish bacteria from nonbacterial features because these features are often of a similar shape and size to the bacteria (Nunan et al., 2001). Another source of errors is the fact that bacterial fluores ...
... intensities then microorganisms. In image analysis it has proved difficult to morphologically distinguish bacteria from nonbacterial features because these features are often of a similar shape and size to the bacteria (Nunan et al., 2001). Another source of errors is the fact that bacterial fluores ...
AUTOPHAGIC VACUOLES PRODUCED IN VITRO
... Continuous phase-contrast observations have been made on macrophages following exposure to chloroquine. The initial abnormality is the appearance in the Golgi region of small vacuoles with an intermediate density between that of pinosomes and granules. Over the course of 1-2 hr these vacuoles grow l ...
... Continuous phase-contrast observations have been made on macrophages following exposure to chloroquine. The initial abnormality is the appearance in the Golgi region of small vacuoles with an intermediate density between that of pinosomes and granules. Over the course of 1-2 hr these vacuoles grow l ...
Primary cilia of human endothelial cells disassemble under laminar
... est concentration of acetyl--tubulin (Fig. 3, A and B). HUVEC primary cilia occasionally were detectable by phase contrast (Fig. 4 B”). HUVEC expressed the highest percentage of primary cilia at passages 2–6. In contrast, they lacked cilia at passages higher than 12. To identify the intracellular l ...
... est concentration of acetyl--tubulin (Fig. 3, A and B). HUVEC primary cilia occasionally were detectable by phase contrast (Fig. 4 B”). HUVEC expressed the highest percentage of primary cilia at passages 2–6. In contrast, they lacked cilia at passages higher than 12. To identify the intracellular l ...
Subset-Specific Reductions in Lung Lymphocyte
... the aorta and supplies oxygenated blood directly to the peribronchial and submucosal tissues (2). Depending on the inciting agent and mode of entry, the pulmonary inflammatory response may be alveolar, bronchial and peribronchial, or a combination of both. Recruitment into alveoli generally occurs a ...
... the aorta and supplies oxygenated blood directly to the peribronchial and submucosal tissues (2). Depending on the inciting agent and mode of entry, the pulmonary inflammatory response may be alveolar, bronchial and peribronchial, or a combination of both. Recruitment into alveoli generally occurs a ...
University of Groningen Effects of structure, morphology and
... hour. Empty PVC loops were used as controls (Ctrl). The data collected from both donors were pooled. The y-axis of figure data also correlate with fibrinogen P2 exposure. ** p < 0.01. ...
... hour. Empty PVC loops were used as controls (Ctrl). The data collected from both donors were pooled. The y-axis of figure data also correlate with fibrinogen P2 exposure. ** p < 0.01. ...
Quantitative profiling of initiating ribosomes in vivo - Shu
... was found between the differences of LTM-captured aTIS density and the ribosome occupancy on the coding region (CDS) (Supplementary Fig. 1c). The lack of quantitative features in GTI-seq largely hampers comparative interrogation of translational regulation. To circumvent this limitation, we set out ...
... was found between the differences of LTM-captured aTIS density and the ribosome occupancy on the coding region (CDS) (Supplementary Fig. 1c). The lack of quantitative features in GTI-seq largely hampers comparative interrogation of translational regulation. To circumvent this limitation, we set out ...
Transient light-induced changes in ion channel
... dark (LD) and dark to light (DL) has a significant effect on the dynamics of ion transport processes both on a whole plant and a cellular level. The nature of the initial response to light transitions is likely to provide important information about the factors that are involved in changes of ion tr ...
... dark (LD) and dark to light (DL) has a significant effect on the dynamics of ion transport processes both on a whole plant and a cellular level. The nature of the initial response to light transitions is likely to provide important information about the factors that are involved in changes of ion tr ...
Basophils and Autoreactive IgE in the Pathogenesis of
... subsets, B cells, monocytes, and dendritic cells in the development of lupus-like disease ([2]). These models have been useful in defining that the pathogenesis of disease lies in the loss of tolerance in the T and B cell compartments [2,3]. B cells themselves were shown to be essential for manifest ...
... subsets, B cells, monocytes, and dendritic cells in the development of lupus-like disease ([2]). These models have been useful in defining that the pathogenesis of disease lies in the loss of tolerance in the T and B cell compartments [2,3]. B cells themselves were shown to be essential for manifest ...
Mechanics and Modeling of Plant Cell Growth
... Mechanical aspects of plant and fungal cell growth Plant development is the result of three essential processes: cell expansive growth, cell division, and cellular differentiation. All three processes have key mechanical aspects that have prompted numerous attempts to generate theoretical, mechanica ...
... Mechanical aspects of plant and fungal cell growth Plant development is the result of three essential processes: cell expansive growth, cell division, and cellular differentiation. All three processes have key mechanical aspects that have prompted numerous attempts to generate theoretical, mechanica ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.