Essays in Biochemistry Volume 39 Chapter 1
... nematode worm Caenorhabditis elegans yielded the second key insight into apoptosis. C. elegans proved invaluable in the study of developmental cell death and painstaking analysis of the lineage of every cell in the adult worm demonstrated that exactly 131 of the 1090 somatic cells generated during d ...
... nematode worm Caenorhabditis elegans yielded the second key insight into apoptosis. C. elegans proved invaluable in the study of developmental cell death and painstaking analysis of the lineage of every cell in the adult worm demonstrated that exactly 131 of the 1090 somatic cells generated during d ...
localization of products of atp hydrolysis in
... further evidence for the participation of this organelle in excitation-contraction coupling. A similar role would be suggested for agranular endoplasmic reticulum in smooth muscle by the demonstration of ATPase activity at this site, although this function may be unlikely in view of the sparsity of ...
... further evidence for the participation of this organelle in excitation-contraction coupling. A similar role would be suggested for agranular endoplasmic reticulum in smooth muscle by the demonstration of ATPase activity at this site, although this function may be unlikely in view of the sparsity of ...
Influence of salinity on the localization of Na+/K+
... Different superscript letters indicate that the means are significantly different from one another (P<0.05, Student–Newman–Keuls test). ...
... Different superscript letters indicate that the means are significantly different from one another (P<0.05, Student–Newman–Keuls test). ...
- Wiley Online Library
... For many years, the bacterial cells were regarded as tiny vessels lacking internal organization. This view, which stemmed from the scarcity of membranebounded organelles, has changed considerably in recent years, mainly due to advancements in imaging capabilities. Consequently, despite the rareness ...
... For many years, the bacterial cells were regarded as tiny vessels lacking internal organization. This view, which stemmed from the scarcity of membranebounded organelles, has changed considerably in recent years, mainly due to advancements in imaging capabilities. Consequently, despite the rareness ...
Examination of the endosomal and lysosomal pathways in
... culture than the parental wild-type cell line. Axenic cell lines have been shown to grow as a result of active fluid phase endocytosis, so it was likely that the slowed growth rate in the myosin I double mutants was due to a defect in this process. This possibility was examined using fluorescein-lab ...
... culture than the parental wild-type cell line. Axenic cell lines have been shown to grow as a result of active fluid phase endocytosis, so it was likely that the slowed growth rate in the myosin I double mutants was due to a defect in this process. This possibility was examined using fluorescein-lab ...
Chemical–Biological Studies of Subcellular Organization in Bacteria
... Another class of putative FtsZ inhibitors that may have significant off-target effects based on their in vivo activity is the Zantrins. The Zantrins consist of a family of small molecules discovered in a screen for modulators of the GTPase activity of recombinant FtsZ.38 Five GTPase inhibitors were ide ...
... Another class of putative FtsZ inhibitors that may have significant off-target effects based on their in vivo activity is the Zantrins. The Zantrins consist of a family of small molecules discovered in a screen for modulators of the GTPase activity of recombinant FtsZ.38 Five GTPase inhibitors were ide ...
Two distinct classes of prestalk
... very low level of expression detectable in overexposed autoradiograms in the absence of DIF. After prolonged incubation without DIF, a low level of expression becomes apparent (Fig. 1). The pDd63 gene might be expected to be responsive to a very low level of DIF, as it is highly induced within 1 h o ...
... very low level of expression detectable in overexposed autoradiograms in the absence of DIF. After prolonged incubation without DIF, a low level of expression becomes apparent (Fig. 1). The pDd63 gene might be expected to be responsive to a very low level of DIF, as it is highly induced within 1 h o ...
3. The Sea Urchin
... actin filaments in the egg cortex produces the fertilization cone (3.17). The fast block to polyspermy, a rapid depolarization of the egg mediated by an influx of sodium ions, provides an initial barrier to penetration of the egg by more than a single sperm. A slower but more permanent block to poly ...
... actin filaments in the egg cortex produces the fertilization cone (3.17). The fast block to polyspermy, a rapid depolarization of the egg mediated by an influx of sodium ions, provides an initial barrier to penetration of the egg by more than a single sperm. A slower but more permanent block to poly ...
Early transcription in Caenorhabditis elegans embryos
... mRNAs, an estimated 20 to 30 of which are expressed at high levels only during this period (Schauer and Wood, 1990). However, these experiments provided only an approximation of the time of transcription onset. We have carried out in vivo assays of early transcription to define more precisely when i ...
... mRNAs, an estimated 20 to 30 of which are expressed at high levels only during this period (Schauer and Wood, 1990). However, these experiments provided only an approximation of the time of transcription onset. We have carried out in vivo assays of early transcription to define more precisely when i ...
Staining Bacteria
... Danish doctor ). He developed a new method to stain bacteria so they can be visible in specimen samples. • Differentiate bacteria into two large groups (the Gram Positive and the Gram negative) • Gram status is important in medicine; the presence or absence of a cell wall will change the bacterium's ...
... Danish doctor ). He developed a new method to stain bacteria so they can be visible in specimen samples. • Differentiate bacteria into two large groups (the Gram Positive and the Gram negative) • Gram status is important in medicine; the presence or absence of a cell wall will change the bacterium's ...
Fission Yeast Bub1 Is a Mitotic Centromere Protein Essential for the
... of spindle assembly. Consistent with this idea, a phosphoepitope recognized by the monoclonal antibody 3F3 is only present at unattached kinetochores in mammalian somatic cell lines (Gorbsky and Ricketts, 1993). Furthermore, the vertebrate homologues of Mad2, Bub1, Mad3 and Bub3 all localize to unat ...
... of spindle assembly. Consistent with this idea, a phosphoepitope recognized by the monoclonal antibody 3F3 is only present at unattached kinetochores in mammalian somatic cell lines (Gorbsky and Ricketts, 1993). Furthermore, the vertebrate homologues of Mad2, Bub1, Mad3 and Bub3 all localize to unat ...
15. THYROID FUNCTION Follicular activity
... by secretory cells. The lumen of the follicles fills with a thick substance called colloid, made out of large proteins containing thyroid hormones. The colloid serves as a reservoir for Thyroid hormones (TH). Within the follicles of the thyroid gland other endocrine cells, called the parafollicular ...
... by secretory cells. The lumen of the follicles fills with a thick substance called colloid, made out of large proteins containing thyroid hormones. The colloid serves as a reservoir for Thyroid hormones (TH). Within the follicles of the thyroid gland other endocrine cells, called the parafollicular ...
15. THYROID FUNCTION Follicular activity
... Two hormones from the hypothalamus and hypophysis respectively are the main regulators of thyroid activity. In response to low temperature the hypothalamus secretes TRH, which reaches the thyrotropes in the hypophysis through the portal system. In the thyrotropes, it stimulates the production of TSH ...
... Two hormones from the hypothalamus and hypophysis respectively are the main regulators of thyroid activity. In response to low temperature the hypothalamus secretes TRH, which reaches the thyrotropes in the hypophysis through the portal system. In the thyrotropes, it stimulates the production of TSH ...
Effect of Brefeldin A on the synthesis and transport of cell wall
... the transport of proteins and glycoproteins along the secretory pathway and also the structure and function of the Golgi apparatus. It causes numerous effects such as (a) the inhibition of vesicular transport of membranes and secretory proteins between the endoplasmic reticulum and Golgi and intra-G ...
... the transport of proteins and glycoproteins along the secretory pathway and also the structure and function of the Golgi apparatus. It causes numerous effects such as (a) the inhibition of vesicular transport of membranes and secretory proteins between the endoplasmic reticulum and Golgi and intra-G ...
Cellular Membranes
... – Each carrier and channel has a unique tertiary shape and therefore is designed to transport a different substance across a membrane • the cell can control the movement of polar molecules through a membrane by controlling the activity of the transporting proteins ...
... – Each carrier and channel has a unique tertiary shape and therefore is designed to transport a different substance across a membrane • the cell can control the movement of polar molecules through a membrane by controlling the activity of the transporting proteins ...
Fc Macrophages via the ERK Pathway Receptor Cross-linking Stimulates Cell Proliferation of *
... Biosciences (San Jose, CA). The secondary horseradish peroxidase-conjugated anti-rabbit (NA 934V) and mouse (NA 931V) antibodies were obtained from Amersham Biosciences (Piscataway, NJ). The primary and secondary antibodies were used at the manufacturer-recommended dilutions for Western blot. Cultur ...
... Biosciences (San Jose, CA). The secondary horseradish peroxidase-conjugated anti-rabbit (NA 934V) and mouse (NA 931V) antibodies were obtained from Amersham Biosciences (Piscataway, NJ). The primary and secondary antibodies were used at the manufacturer-recommended dilutions for Western blot. Cultur ...
Cancer stem cells and addicted cancer cells
... modest [1]. Pivotal questions like ‘what signaling pathways are involved in tumor cell growth’ and ‘what causes tumor cell heterogeneity and metastasis’ have only partly been answered. A better understanding of these fundamental processes fuel the hope that more effective, targeted cancer therapies ...
... modest [1]. Pivotal questions like ‘what signaling pathways are involved in tumor cell growth’ and ‘what causes tumor cell heterogeneity and metastasis’ have only partly been answered. A better understanding of these fundamental processes fuel the hope that more effective, targeted cancer therapies ...
purification and amino acid analysis of two human glioma
... Two chemotactic peptides for human monocytes, GDCF 1 and GDCF 2, were purified to apparent homogeneity from culture fluid of a human glioma cell line. Although these two peptides were separated into two completely distinct peaks by CM-HPLC chromatography, their elution patterns from a reverse phase ...
... Two chemotactic peptides for human monocytes, GDCF 1 and GDCF 2, were purified to apparent homogeneity from culture fluid of a human glioma cell line. Although these two peptides were separated into two completely distinct peaks by CM-HPLC chromatography, their elution patterns from a reverse phase ...
Neurophysiology
... flow does not re-excite previously active area because this area is in its refractory period ...
... flow does not re-excite previously active area because this area is in its refractory period ...
oleandrin
... menstrual pain, epilepsy, cancer, paralysis, skin disease, cardiac problems (traditional Chinese), insecticide, eczema, psoriasis, herpes, malaria, leprosy, used in both ancient and more recent times for suicide • Today: many websites detail how to make homeopathic cancer fighting “oleander soup” at ...
... menstrual pain, epilepsy, cancer, paralysis, skin disease, cardiac problems (traditional Chinese), insecticide, eczema, psoriasis, herpes, malaria, leprosy, used in both ancient and more recent times for suicide • Today: many websites detail how to make homeopathic cancer fighting “oleander soup” at ...
Neurophysiology
... flow does not re-excite previously active area because this area is in its refractory period ...
... flow does not re-excite previously active area because this area is in its refractory period ...
chiasma formation occurs at or following mid-prophase
... could be obtained. Obtaining 30 analysable cells in diplotene is a monumental task for the following reasons. Subsequent to pachytene of meiosis the bivalents form a typical diplotene configuration. However, this stage must be a relatively short one since it is present in only a few of the ovarioles ...
... could be obtained. Obtaining 30 analysable cells in diplotene is a monumental task for the following reasons. Subsequent to pachytene of meiosis the bivalents form a typical diplotene configuration. However, this stage must be a relatively short one since it is present in only a few of the ovarioles ...
Bio1A - Lec 6 slides File
... • structural role - to bear tension, resisting pulling forces within the cell ...
... • structural role - to bear tension, resisting pulling forces within the cell ...
The pollen wall and tapetum are altered in the
... between plasma membrane and the nexine (Heslop-Harrison, 1971), and contains cellulose, pectin, and various proteins (Owen and Makaroff, 1995). The morphological features of the tectum, bacula, and nexine vary considerably, but they are the most representative structural characteristics of the polle ...
... between plasma membrane and the nexine (Heslop-Harrison, 1971), and contains cellulose, pectin, and various proteins (Owen and Makaroff, 1995). The morphological features of the tectum, bacula, and nexine vary considerably, but they are the most representative structural characteristics of the polle ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.