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Selection and the Origin of Cells
Selection and the Origin of Cells

... together by internal hydrophobic interactions or had a spontaneously formed, semipermeable bounding layer generated by chemical cross-linking or by self-assembly of lipidlike molecules (the latter would arguably constitute protocells). The implicit or overt argument is that these precellular entitie ...
Document
Document

... Materials and Methods: Positively and negatively charged ISCOMATRIX were prepared. BALB/C mice were immunized subcutaneously, three times with 2-week intervals, with different ISCOMATRIX formulations. Soluble Leishmania antigens (SLA) were mixed with ISCOMATRIX right before injection. The extent of ...
DOCTORAL THESIS
DOCTORAL THESIS

... efficacy both in vitro and in vivo. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials. ...
Individual-based modelling of growth and migration of Salmonella
Individual-based modelling of growth and migration of Salmonella

... justified by its thickness of only 11–15 Am (AbouAshour and Edwards, 1970). Once a cell reaches the vitelline membrane, it sticks to this membrane for a certain period after which it enters the yolk. This is equivalent to supposing that the membrane holds back bacteria initially, but deteriorates af ...
Developmental genetics of the Caenorhabditis elegans pharynx
Developmental genetics of the Caenorhabditis elegans pharynx

... from anterior to posterior, the procorpus, the metacorpus, the isthmus, and the posterior bulb in which the grinder is located (Figure 1(a)). The mature pharynx is composed of 62 cells containing 80 nuclei; many cells are multinucleate as a result of cell fusions. There are five types of pharyngeal ...
Coding of Border Ownership in Monkey Visual Cortex
Coding of Border Ownership in Monkey Visual Cortex

... setup 2 for animals M13 and M16 (in the results to be presented below, the first digits of the neuron identification numbers indicate the animal). In setup 1, visual stimuli were generated by an Omnicomp GDS 2000 processor controlled by a personal computer and displayed on a Hitachi HM4119 color mon ...
Similarities and differences in the responses of microorganisms to
Similarities and differences in the responses of microorganisms to

... more rapid rate than iodine (from Lugol’s iodine). Chlorine is also a much more effective sporicide. In both cases, uptake is increased when coat-deficient spores are used.36,37 It is likely that the coats act as an efficient barrier especially to the entry of iodine. Uptake of both chlorine and iod ...
Production of macrophage activating factors by the mitogen
Production of macrophage activating factors by the mitogen

Microalgae Synthesize Hydrocarbons from Long
Microalgae Synthesize Hydrocarbons from Long

... (Supplemental Fig. S1). The finding that all these hydrocarbons were absent from control samples generated by saponification of fresh culture medium ruled out that any hydrocarbons had been introduced as contamination from solvents, reagents, or culture medium (Fig. 1A). In order to further exclude th ...
cilia regeneration in tetrahymena and its inhibition
cilia regeneration in tetrahymena and its inhibition

... Systems of regenerating cilia and flagella in the protozoans have been shown to offer many advantages for the investigation of various aspects of the synthesis and assembly of ciliary and flagellar microtubules (3, 11, 12). It was of interest to determine the effect of colchicine on the regeneration ...
Full text  - 2nd International Conference of the
Full text - 2nd International Conference of the

... transmission of small RNA’s (c. 25 nucleotides) as ―gene silencers.‖ Special attention is being given to the sieve element-companion-cell complex which has been shown to transmit proteins of 27kD in size. An important future goal will be to elucidate the plasmodesmal functions in and near apical mer ...
here - The Nebenführ Lab
here - The Nebenführ Lab

... present only in some TVS, with their presence mainly restricted to the G2 phase of the cell cycle (Hasezawa et al. 1991, Kutsuna and Hasezawa 2002). TVS microtubules appear to be necessary for nuclear migration in tobacco BY-2 cells in preparation for cell division (Katsuta et al. 1990) but play lit ...
Dephosphorylation Agents Depress Gap Junctional Communication
Dephosphorylation Agents Depress Gap Junctional Communication

... molecules (< 1000 Da), including second messengers (e.g. cAMP, inositol triphosphate and Ca2+ ) between contacting cells. They differ from other membrane channels since they exist between two cells, they are relatively non-specific, and the movement of ions and molecules through them occurs by passive ...
Correlation between Innervation of Skeletal Muscles and
Correlation between Innervation of Skeletal Muscles and

... unit potentials began to appear successively in all the groups; and muscle action potentials at very low wave amplitude could be detected by stimulating the transpositioned nerve, but no significant differences were found among the different groups. At 8 w, the latency periods and wave amplitudes of ...
Chlorella
Chlorella

... limited nutrient pool available. Before phagotrophy, prevalent selection pressures among Precambrian phototrophs were for ecient nutrient competition (e.g. a high surface-to-volume ratio provided by small cell size). However, with the advent of phagotrophy, resistance from this new mortality factor ...
Original Article Differences in MEK inhibitor efficacy in molecularly
Original Article Differences in MEK inhibitor efficacy in molecularly

... are one of the most common mutations found in cancer and multiple allosteric MEK inhibitors (MEKi), have been developed and used in many cancer types [21, 22]. Recently, an important phase II clinical trial evaluated the MEKi selumetinib, reporting response rates of 15% in patients with recurrent LG ...
9700/04 - StudyGuide.PK
9700/04 - StudyGuide.PK

... Write your Centre number, candidate number and name in the spaces provided at the top of this page. Write in dark blue or black pen in the spaces provided on the Question Paper. You may use a soft pencil for any diagrams, graphs or rough working. Do not use staples, paper clips, highlighters, glue o ...
Biosorption of copper from aqueous environments by Micrococcus
Biosorption of copper from aqueous environments by Micrococcus

... and complexation by binding proteins such as metallothioneins or phytochelatins (Mejare and Bulow, 2001). In the genomic sequence a repertoire of functions was annotated that deal with metals. Both chromosomal and plasmid genes are involved in this resistance. In M. luteus the genes of the MerR/ArsR ...
Evolutionary aspects of non-cell-autonomous regulation in vascular
Evolutionary aspects of non-cell-autonomous regulation in vascular

... to our knowledge, only one exception, namely, the unique structure of expanded PD in angle and apical meristems of Selaginella willdenovii (Wochok and Clayton, 1976). A prominent feature of PD in angiosperms is their participation in the cell-to-cell spread of viruses. Interestingly, there are very ...
the Kancera Project Update Feb. 2017
the Kancera Project Update Feb. 2017

Metabolic Basis of Visual Cycle Inhibition by Retinoid and
Metabolic Basis of Visual Cycle Inhibition by Retinoid and

Treating sickle cell disease by targeting HbS
Treating sickle cell disease by targeting HbS

... Before considering different ways of decreasing fiber formation, it is important to point out that therapeutic benefit does not require complete inhibition of HbS polymerization. The rates of oxygen binding and dissociation are so fast (milliseconds) that the fractional saturation of normal hemoglob ...
The lipid phosphatase LPP3 regulates extra
The lipid phosphatase LPP3 regulates extra

... action as intracellular second messengers, although they may also be acting through other, as yet unidentified, receptors. Given their effects on cells, recent evidence has revealed that these lipid mediators are important to embryogenesis, particularly in guiding cell migration. This was first show ...
Implications for AIDS Simian Immunodeficiency Virus Infection of
Implications for AIDS Simian Immunodeficiency Virus Infection of

... In contrast to HIV-infected humans, naturally SIV-infected sooty mangabeys (SMs) very rarely progress to AIDS. Although the mechanisms underlying this disease resistance are unknown, a consistent feature of natural SIV infection is the absence of the generalized immune activation associated with HIV ...
Expression of the chicken GATA factor family during
Expression of the chicken GATA factor family during

... Engel, unpublished observations). In this study, we show first that multiple GATA factors are expressed in human and murine erythroid cells, just as in avian erythroid cells (Yamamoto et al., 1990). Second, we find distinct quantitative changes in cGATA mRNA levels in differentiating definitive chic ...
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Cell encapsulation



Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.
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