Introduction Cell Cycle
... continue to increase (for some time) in the absence of DNA replication and cell division. We will see how this behavior has been used to study the coordination and timing of cell cycle processes. At this point, the important conclusion is that under normal growth conditions (in the absence of inhibi ...
... continue to increase (for some time) in the absence of DNA replication and cell division. We will see how this behavior has been used to study the coordination and timing of cell cycle processes. At this point, the important conclusion is that under normal growth conditions (in the absence of inhibi ...
A tour of the cell - The Open University
... The subcellular components can then be recovered by centrifugation. The cell homogenate is dispensed into centrifuge tubes which are placed into a rotating holder (known as a rotor) that fits into the centrifuge. As the rotor turns, particles suspended in the homogenate migrate towards the bottom of ...
... The subcellular components can then be recovered by centrifugation. The cell homogenate is dispensed into centrifuge tubes which are placed into a rotating holder (known as a rotor) that fits into the centrifuge. As the rotor turns, particles suspended in the homogenate migrate towards the bottom of ...
Chapter 13 - Fission Yeast TOR and Rapamycin
... compensate for the sensitivity to osmotic stress, high temperature or thialysine in the double mutant Drhb1 tor2act cells. Thus, Rhb1 may also regulate amino acid uptake or survival under stress conditions in a Tor2-independent manner [26]. The possibility that Rhb1 may regulate other proteins besid ...
... compensate for the sensitivity to osmotic stress, high temperature or thialysine in the double mutant Drhb1 tor2act cells. Thus, Rhb1 may also regulate amino acid uptake or survival under stress conditions in a Tor2-independent manner [26]. The possibility that Rhb1 may regulate other proteins besid ...
Embodied Computation Applying the Physics of Computation to Artificial Morphogenesis
... In general terms our approach is to take natural morphogenetic processes, express them mathematically (if not already done in the literature), and understand them in general physical terms (e.g., diffusion, adhesion, attraction, stress, pressure). This abstract description is the essence of the embo ...
... In general terms our approach is to take natural morphogenetic processes, express them mathematically (if not already done in the literature), and understand them in general physical terms (e.g., diffusion, adhesion, attraction, stress, pressure). This abstract description is the essence of the embo ...
“Understanding dissemination of Mycobacterium tuberculosis from
... demonstrate a role for ESAT-6 in the direct crossing of M. tb across the alveolar barrier. ...
... demonstrate a role for ESAT-6 in the direct crossing of M. tb across the alveolar barrier. ...
complement
... This function is evident in patients with SLE Complement deficiency ( C4 ) leads to SLE as it interfere with effective solubilization & clearance of immune complexes which in turn leads to their persistence ...
... This function is evident in patients with SLE Complement deficiency ( C4 ) leads to SLE as it interfere with effective solubilization & clearance of immune complexes which in turn leads to their persistence ...
Induction of Lytic Epstein-Barr Virus (EBV) Infection in EBV
... expression of EBV early genes (12–18). BZLF1 expression is sufficient to trigger induction of lytic infection in both B cells and epithelial cells (12–14, 19 –22), and BRLF1 expression can induce lytic EBV infection efficiently in epithelial cells (22). Thus, delivery of either the BZLF1 or BRLF1 pr ...
... expression of EBV early genes (12–18). BZLF1 expression is sufficient to trigger induction of lytic infection in both B cells and epithelial cells (12–14, 19 –22), and BRLF1 expression can induce lytic EBV infection efficiently in epithelial cells (22). Thus, delivery of either the BZLF1 or BRLF1 pr ...
7-2 Eukaryotic Cell Structure
... There are two types of ER—rough and smooth. The portion of the ER involved in protein synthesis is called rough endoplasmic reticulum, or rough ER. Ribosomes are found on the surface of rough ER. Rough ER is abundant in cells that produce large amounts of protein for export. ...
... There are two types of ER—rough and smooth. The portion of the ER involved in protein synthesis is called rough endoplasmic reticulum, or rough ER. Ribosomes are found on the surface of rough ER. Rough ER is abundant in cells that produce large amounts of protein for export. ...
7-2 Eukaryotic Cell Structure
... There are two types of ER—rough and smooth. The portion of the ER involved in protein synthesis is called rough endoplasmic reticulum, or rough ER. Ribosomes are found on the surface of rough ER. Rough ER is abundant in cells that produce large amounts of protein for export. ...
... There are two types of ER—rough and smooth. The portion of the ER involved in protein synthesis is called rough endoplasmic reticulum, or rough ER. Ribosomes are found on the surface of rough ER. Rough ER is abundant in cells that produce large amounts of protein for export. ...
7-2 Eukaryotic Cell Structure
... There are two types of ER—rough and smooth. The portion of the ER involved in protein synthesis is called rough endoplasmic reticulum, or rough ER. Ribosomes are found on the surface of rough ER. Rough ER is abundant in cells that produce large amounts of protein for export. ...
... There are two types of ER—rough and smooth. The portion of the ER involved in protein synthesis is called rough endoplasmic reticulum, or rough ER. Ribosomes are found on the surface of rough ER. Rough ER is abundant in cells that produce large amounts of protein for export. ...
Cell Membrane Quiz 2013
... b. the concentration of a solution is never the same throughout a solution. c. the concentration of a solution is always the same throughout a solution. d. molecules never move or collide with each other. ____ 12. When the concentration of molecules on both sides of a membrane is the same, the molec ...
... b. the concentration of a solution is never the same throughout a solution. c. the concentration of a solution is always the same throughout a solution. d. molecules never move or collide with each other. ____ 12. When the concentration of molecules on both sides of a membrane is the same, the molec ...
LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and
... phosphatase and used as a substrate for an in vitro kinase assay incorporating recombinant active LATS1 kinase (see Mate rials and methods). The screening process identified YAP1 (Yes-associated protein 1), a well-known target for LATS1 (Huang et al., 2005), with high frequency (Table 1), thereby c ...
... phosphatase and used as a substrate for an in vitro kinase assay incorporating recombinant active LATS1 kinase (see Mate rials and methods). The screening process identified YAP1 (Yes-associated protein 1), a well-known target for LATS1 (Huang et al., 2005), with high frequency (Table 1), thereby c ...
Heat stress-induced localization of small heat shock
... identity, 57% similarity) with aB-crystallin, immunostaining with an Hsp25-specific antibody shows that this protein is mostly found in the cytoplasm with little or no distribution in the nucleus (Fig. 1D). Members of another class of heat shock proteins, Hsp70 and its constitutive isoform, Hsc70, a ...
... identity, 57% similarity) with aB-crystallin, immunostaining with an Hsp25-specific antibody shows that this protein is mostly found in the cytoplasm with little or no distribution in the nucleus (Fig. 1D). Members of another class of heat shock proteins, Hsp70 and its constitutive isoform, Hsc70, a ...
Retinal Ganglion Cells in Goldfish
... mechanical controls of the stage and fine focus. Data points were entered sequentially, every 5-l 0 pm, along the length of the dendrite, beginning at the soma. The computer provided summaries ofthe number ofbranch points and total dendritic length for an individual cell, and generated a drawing (e. ...
... mechanical controls of the stage and fine focus. Data points were entered sequentially, every 5-l 0 pm, along the length of the dendrite, beginning at the soma. The computer provided summaries ofthe number ofbranch points and total dendritic length for an individual cell, and generated a drawing (e. ...
Microtubules and the Evolution of Mitosis
... course of plant evolution, and are now absent, as in most seed plants. In addition to these structural differences, the molecular composition of associated proteins also deviates to a degree that sequence homologues of important animal microtubule associated proteins (MAPs) seem to be absent in high ...
... course of plant evolution, and are now absent, as in most seed plants. In addition to these structural differences, the molecular composition of associated proteins also deviates to a degree that sequence homologues of important animal microtubule associated proteins (MAPs) seem to be absent in high ...
Most Human Proteins Made in Both Nucleus and Cytoplasm Turn
... In bacteria, protein synthesis can be coupled to transcription, but in eukaryotes it is believed to occur solely in the cytoplasm. Using pulses as short as 5 s, we find that three analogues – L-azidohomoalanine, puromycin (detected after attaching fluors using ‘click’ chemistry or immuno-labeling), ...
... In bacteria, protein synthesis can be coupled to transcription, but in eukaryotes it is believed to occur solely in the cytoplasm. Using pulses as short as 5 s, we find that three analogues – L-azidohomoalanine, puromycin (detected after attaching fluors using ‘click’ chemistry or immuno-labeling), ...
- Wiley Online Library
... for satellite cells to migrate to the lesion focus in order to carry out cellular tissue repair. Recent work using high-resolution in vivo imaging of muscle has shown the directional movement of satellite cells to the site of myofiber damage [10]. Furthermore, matrix metalloproteinase, which promotes ...
... for satellite cells to migrate to the lesion focus in order to carry out cellular tissue repair. Recent work using high-resolution in vivo imaging of muscle has shown the directional movement of satellite cells to the site of myofiber damage [10]. Furthermore, matrix metalloproteinase, which promotes ...
MERCURY-INDUCED AUTOIMMUNITY: GENETICS AND IMMUNOREGULATION Doctorial Thesis from the Department of Immunology
... against its own tissue (reviewed in Silverstein and Rose 1997). Between 1930 to early 1960, the dominant theory was an instruction theory, which offered an explanation for the large repertoire of antibody specificities, by suggesting that the antigen act as a template for the globulin producing mach ...
... against its own tissue (reviewed in Silverstein and Rose 1997). Between 1930 to early 1960, the dominant theory was an instruction theory, which offered an explanation for the large repertoire of antibody specificities, by suggesting that the antigen act as a template for the globulin producing mach ...
The syndapin protein family: linking membrane trafficking with the
... The formation and movement of vesicles, as well as the organization of different pools of vesicles within distinct compartments of cells, are thought to involve cytoskeletal elements; however, how the different molecular machineries involved are interconnected is mostly unclear (Qualmann et al., 200 ...
... The formation and movement of vesicles, as well as the organization of different pools of vesicles within distinct compartments of cells, are thought to involve cytoskeletal elements; however, how the different molecular machineries involved are interconnected is mostly unclear (Qualmann et al., 200 ...
The Interleukin-1 Family: Back to the Future
... amounts of actively secreted IL-1b. Elevated secretion of IL-1b is linked to inflammation in patients with these mutations, termed autoinflammatory diseases. However, not all IL-1b-mediated inflammation is due to NLRP3 or caspase-1 activity. Mice deficient in caspase-1 develop the same IL-1b-mediate ...
... amounts of actively secreted IL-1b. Elevated secretion of IL-1b is linked to inflammation in patients with these mutations, termed autoinflammatory diseases. However, not all IL-1b-mediated inflammation is due to NLRP3 or caspase-1 activity. Mice deficient in caspase-1 develop the same IL-1b-mediate ...
Mouse mammary tumor virus-based vector transduces non
... posttranscriptional regulatory functions. Results: Using this system, vector particles were produced to markedly greater titers (>1000-fold) than those obtained previously. The titers (>106 transduction units /ml) were comparable to those achieved with lentiviral or gammaretroviral vectors. Importan ...
... posttranscriptional regulatory functions. Results: Using this system, vector particles were produced to markedly greater titers (>1000-fold) than those obtained previously. The titers (>106 transduction units /ml) were comparable to those achieved with lentiviral or gammaretroviral vectors. Importan ...
The dendritic cell side of the immunological synapse
... multiple T cells simultaneously (18, 37, 38). This second phase is observed within 3 h after phase 1 (18, 37), although the precise onset depends on the antigen dose and the number of DCs presenting the cognate antigen (40). The DC/T cell clusters during this phase are very stable and can even be is ...
... multiple T cells simultaneously (18, 37, 38). This second phase is observed within 3 h after phase 1 (18, 37), although the precise onset depends on the antigen dose and the number of DCs presenting the cognate antigen (40). The DC/T cell clusters during this phase are very stable and can even be is ...
Compartmentalisation of Rho regulators directs cell
... Evidence that the spatial and temporal control of small RhoGTPase function must be correlated with the activity of Rho regulators during tissue morphogenesis is suggested from studies on cell shape changes occurring during gastrulation and neurulation. In Drosophila gastrulation, a secreted factor F ...
... Evidence that the spatial and temporal control of small RhoGTPase function must be correlated with the activity of Rho regulators during tissue morphogenesis is suggested from studies on cell shape changes occurring during gastrulation and neurulation. In Drosophila gastrulation, a secreted factor F ...
Complex Receptive Fields in Primary Visual Cortex
... (Kelly and Van Essen 1974; Gilbert and Wiesel 1979; Martin and Whitteridge 1984; Hirsch and others 1998, 2002; Martinez and others 1999, 2002). Second, in vivo recordings from neurons that were intracellularly labeled demonstrated that most layer 4 simple cells project to the superficial layers of t ...
... (Kelly and Van Essen 1974; Gilbert and Wiesel 1979; Martin and Whitteridge 1984; Hirsch and others 1998, 2002; Martinez and others 1999, 2002). Second, in vivo recordings from neurons that were intracellularly labeled demonstrated that most layer 4 simple cells project to the superficial layers of t ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.