
mbn cells results in dysregulation of Fer1HCH expression
... yeast ΔMrs3ΔMrs4 double mutant, which shows a growth defect on low-iron medium. The WT (wild-type) strain was able to grow on iron-replete and low-iron medium, while the double mutant transfected with empty vector grew only on iron-replete medium (Figure 3). This growth defect was rescued by ectopic ...
... yeast ΔMrs3ΔMrs4 double mutant, which shows a growth defect on low-iron medium. The WT (wild-type) strain was able to grow on iron-replete and low-iron medium, while the double mutant transfected with empty vector grew only on iron-replete medium (Figure 3). This growth defect was rescued by ectopic ...
Cajal bodies and coilin—moving towards function
... CBs are found in the nuclei of plant and animal cells. This strong conservation suggests that they may play an important role, although it has proved difficult to pin down what function(s) they perform. The number and size of CBs varies among cell types (in mammalian cells typically 0–10 CBs per nuc ...
... CBs are found in the nuclei of plant and animal cells. This strong conservation suggests that they may play an important role, although it has proved difficult to pin down what function(s) they perform. The number and size of CBs varies among cell types (in mammalian cells typically 0–10 CBs per nuc ...
molecular mechanisms of mechanoperception in plants
... Mechanisms of Mechanoperception While it is very clear that plants tissues and cells sense and respond to mechanical signals, as summarized above, the various molecular mechanisms by which this is accomplished are still a major area of investigation. Below we describe current research into two major ...
... Mechanisms of Mechanoperception While it is very clear that plants tissues and cells sense and respond to mechanical signals, as summarized above, the various molecular mechanisms by which this is accomplished are still a major area of investigation. Below we describe current research into two major ...
How Have Plant Cell Walls Evolved?1
... functional requirements may have driven the evolution of particular biosynthetic capacities. Although many antibodies are available for plant cell wall research, it is usually a considerable challenge to identify with precision the epitopes on polysaccharides to which they bind (Moller et al., 2008) ...
... functional requirements may have driven the evolution of particular biosynthetic capacities. Although many antibodies are available for plant cell wall research, it is usually a considerable challenge to identify with precision the epitopes on polysaccharides to which they bind (Moller et al., 2008) ...
A conserved role for kinesin-5 in plant mitosis
... Kinesin-5 motors are present in plants (Reddy and Day, 2001). In tobacco, the kinesin-5, TKRP125, was inferred to be involved in separating anti-parallel microtubules in the cytokinetic organelle, the phragmoplast (Asada et al., 1997). In the arabidopsis genome, four sequences have been annotated as ...
... Kinesin-5 motors are present in plants (Reddy and Day, 2001). In tobacco, the kinesin-5, TKRP125, was inferred to be involved in separating anti-parallel microtubules in the cytokinetic organelle, the phragmoplast (Asada et al., 1997). In the arabidopsis genome, four sequences have been annotated as ...
Structure of the plasma membrane T2T
... exposed to the cytoplasm or extracellular fluid tend to be hydrophilic. Transmembrane proteins may cross the membrane just once, or may have as many as twelve different membrane-spanning sections. A typical membranespanning segment consists of 20-25 hydrophobic amino acids arranged in an alpha helix ...
... exposed to the cytoplasm or extracellular fluid tend to be hydrophilic. Transmembrane proteins may cross the membrane just once, or may have as many as twelve different membrane-spanning sections. A typical membranespanning segment consists of 20-25 hydrophobic amino acids arranged in an alpha helix ...
Autophagy in Tobacco BY-2 Cells Cultured under
... starvation conditions. We have previously suggested that this bulk degradation of cellular proteins is performed by autophagy, where autolysosomes formed de novo act as the major lytic compartments. The digestion process in autolysosomes can be retarded by addition of the cysteine protease inhibitor ...
... starvation conditions. We have previously suggested that this bulk degradation of cellular proteins is performed by autophagy, where autolysosomes formed de novo act as the major lytic compartments. The digestion process in autolysosomes can be retarded by addition of the cysteine protease inhibitor ...
Dynamic Localization of the DNA Replication
... on DNA and that the MCM complex is stable under high-salt conditions. Our results are consistent with a conserved replicative helicase function for the MCM complex in plants but not with the idea that plants resemble budding yeast by actively exporting the MCM complex from the nucleus to prevent una ...
... on DNA and that the MCM complex is stable under high-salt conditions. Our results are consistent with a conserved replicative helicase function for the MCM complex in plants but not with the idea that plants resemble budding yeast by actively exporting the MCM complex from the nucleus to prevent una ...
In yeast, the pseudohyphal phenotype induced by isoamyl alcohol
... nutrient source may also act to trigger pseudohyphae formation as a foraging mechanism to search for better conditions. The mechanism by which fusel alcohols trigger pseudohyphae formation is poorly understood, but it is clearly different from that operating during nitrogen-limited growth because it ...
... nutrient source may also act to trigger pseudohyphae formation as a foraging mechanism to search for better conditions. The mechanism by which fusel alcohols trigger pseudohyphae formation is poorly understood, but it is clearly different from that operating during nitrogen-limited growth because it ...
Type IV collagen, laminin, and fibronectin promote the
... described earlier. Second passage cells were incubated in 35S amino acids (5 /iCi/ml) for 24 hours before use, while in log phase growth. Immulon 96 well plates (Dynatech Laboratories Inc., Chantilly, VA) were coated with type IV collagen, laminin, or fibronectin in phosphate-buffered saline for 18 ...
... described earlier. Second passage cells were incubated in 35S amino acids (5 /iCi/ml) for 24 hours before use, while in log phase growth. Immulon 96 well plates (Dynatech Laboratories Inc., Chantilly, VA) were coated with type IV collagen, laminin, or fibronectin in phosphate-buffered saline for 18 ...
Geographic Information Systems - CEProfs
... statistics of the cell values within each zone. Table rows correspond to zones and columns to statistics. The statistics are: majority, maximum, mean, median, minimum, minority, range, standard deviation, sum and variety. The zones can be defined by polygons or (integer) grid cells with the same val ...
... statistics of the cell values within each zone. Table rows correspond to zones and columns to statistics. The statistics are: majority, maximum, mean, median, minimum, minority, range, standard deviation, sum and variety. The zones can be defined by polygons or (integer) grid cells with the same val ...
Review Article Stem cells for the cell and molecular therapy of type 1
... iPSCs have been generated from patients with T1D by using three factors (OCT4, SOX2, and KLF4), and excluding the tumorigenic gene C-MYC [32]. Obviously, further studies are required to confirm the efficiency of methods to generate iPSCs from different human somatic cells. Mesenchymal Stem Cells (MS ...
... iPSCs have been generated from patients with T1D by using three factors (OCT4, SOX2, and KLF4), and excluding the tumorigenic gene C-MYC [32]. Obviously, further studies are required to confirm the efficiency of methods to generate iPSCs from different human somatic cells. Mesenchymal Stem Cells (MS ...
The TOR signalling network from yeast to man
... While it is not known how, or even if, y/mTORC2 is regulated, y/mTORC1 is—via yet poorly understood mechanisms—regulated by nutrient quality and/or abundance. In addition, mTORC1 activity is influenced by growth factors, energy, and cellular stress, and recent studies in fly and mammalian tissue cul ...
... While it is not known how, or even if, y/mTORC2 is regulated, y/mTORC1 is—via yet poorly understood mechanisms—regulated by nutrient quality and/or abundance. In addition, mTORC1 activity is influenced by growth factors, energy, and cellular stress, and recent studies in fly and mammalian tissue cul ...
Cellular and Antitumor Activity of a New Diethylene Glycol
... peak near 690 nm, a wavelength that penetrates tissue relatively efficiently. Another advantage is that upon activation, there is a high quantum yield of singlet oxygen (5). Lemuteporfin is presently being investigated clinically in photodynamic therapy (6). The photodynamic efficacy of photosensiti ...
... peak near 690 nm, a wavelength that penetrates tissue relatively efficiently. Another advantage is that upon activation, there is a high quantum yield of singlet oxygen (5). Lemuteporfin is presently being investigated clinically in photodynamic therapy (6). The photodynamic efficacy of photosensiti ...
Named cells in dermatology - Indian Journal of Dermatology
... Are distributed in the epidermis (preference for a suprabasal position), oral cavity, esophagus and vagina.[1] They serve as the antigenprocessing and presenting cells.[1] They are reduced in the epidermis of patients with diseases like psoriasis, sarcoidosis and contact dermatitis, and increased in ...
... Are distributed in the epidermis (preference for a suprabasal position), oral cavity, esophagus and vagina.[1] They serve as the antigenprocessing and presenting cells.[1] They are reduced in the epidermis of patients with diseases like psoriasis, sarcoidosis and contact dermatitis, and increased in ...
Skeletal Muscles
... sarcomere in the fiber must contract simultaneously and not in sequence. This simultaneous contraction - not only in a single fiber but throughout an entire muscle - is brought about by the T-system. The force of muscle contraction is transmitted to the extracellular matrix through a series of link ...
... sarcomere in the fiber must contract simultaneously and not in sequence. This simultaneous contraction - not only in a single fiber but throughout an entire muscle - is brought about by the T-system. The force of muscle contraction is transmitted to the extracellular matrix through a series of link ...
Integrin inside-out signaling and
... Integrins are heterodimers of noncovalently associated a and b subunits, which each contain large N-terminal extracellular domains, single-span transmembrane domains (TMD), and C-terminal cytoplasmic domains (Figure 1). Eighteen a and eight b subunits come together to form 24 different integrin hete ...
... Integrins are heterodimers of noncovalently associated a and b subunits, which each contain large N-terminal extracellular domains, single-span transmembrane domains (TMD), and C-terminal cytoplasmic domains (Figure 1). Eighteen a and eight b subunits come together to form 24 different integrin hete ...
mutant alleles of polymitotic that disrupt the cell cycle
... not shown). However, even within one tetrad, asynchronous cell divisions are observed in late stages of meiosis II (Fig. 2A and B). In Fig. 2A, two of the tetrads have not yet completed cytokinesis, while the other two have entered the equivalent of a post-tetrad interphase. The interphase nuclear m ...
... not shown). However, even within one tetrad, asynchronous cell divisions are observed in late stages of meiosis II (Fig. 2A and B). In Fig. 2A, two of the tetrads have not yet completed cytokinesis, while the other two have entered the equivalent of a post-tetrad interphase. The interphase nuclear m ...
Journal of Biological Chemistry. 2004 Feb 20
... required for stable attachment of epithelial cells to the lamina densa (1). Kindlerin displays similarity throughout its sequence to two other human proteins, Mig-2 (65% identity) and URP2 (57% identity) as shown in Figure 1 and appears to be related to the C. elegans protein, UNC112 (44% identity). ...
... required for stable attachment of epithelial cells to the lamina densa (1). Kindlerin displays similarity throughout its sequence to two other human proteins, Mig-2 (65% identity) and URP2 (57% identity) as shown in Figure 1 and appears to be related to the C. elegans protein, UNC112 (44% identity). ...
Lecture 10
... isolated or in small groups (the diffuse endocrine system) and include many of the endocrine cells of the intestine. The APUD concept was originally conceived owing to the fact that most of the polypeptide-secreting endocrine cells have several common ultrastructural and biochemical characteristics ...
... isolated or in small groups (the diffuse endocrine system) and include many of the endocrine cells of the intestine. The APUD concept was originally conceived owing to the fact that most of the polypeptide-secreting endocrine cells have several common ultrastructural and biochemical characteristics ...
4)Cell wall
... own food from simple compounds as plants are able to do. So they are dependent on other organisms to produce their foods, e.g., sugars, starches, proteins, fats, etc. Fungi can be further divided into saprobes, parasites, symbionts, facultative parasites and facultative saprobes. 2-The food gatherin ...
... own food from simple compounds as plants are able to do. So they are dependent on other organisms to produce their foods, e.g., sugars, starches, proteins, fats, etc. Fungi can be further divided into saprobes, parasites, symbionts, facultative parasites and facultative saprobes. 2-The food gatherin ...
Extracellular matrix

In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).