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Botanicals as Therapeutics
Botanicals as Therapeutics

... little recognition in the United States concerning its potential to benefit various perturbations of the prostate. Ironically, it may be the best natural product for this condition currently available. In 1950, a Swedish beekeeper found a way to␣ collect pollen artificially (Preuss and Adderly, 1998 ...
zontivity pi
zontivity pi

... Both male and female pups displayed transient effects on sensory function and neurobehavioral development at weaning at 67 times the human exposure at the RHD, whereas female pups displayed decreased memory at 31 times the human exposure at the RHD. However, animal studies are not always predictive ...
(1) Superficial infections
(1) Superficial infections

... • Ketoconazole, Itraconozole, Voriconazole and Fluconazole are used systemically. • Ketoconazole was the first azole that could be given orally to treat systemic fungal infections. ...
Lithium Adverse Effects
Lithium Adverse Effects

... • Depakote initial dose: 750 mg/day PO in divided doses • Depakote ER initial dose: 25 mg/kg PO once daily. Increase as rapidly as possible to achieve the lowest therapeutic dose that provides desired clinical effect or plasma concentration • Doses should not exceed 60 mg/kg/day ...
PHARMACOLOGY OF ANTIPSYCHOTIC DRUGS (NEUROLEPTICS)
PHARMACOLOGY OF ANTIPSYCHOTIC DRUGS (NEUROLEPTICS)

... Parkinsonian-like syndrome is characterized by tremors, bradykinesia, rigidity, and other signs of parkinsonism. This syndrome can develop from 5 days to weeks into treatment. ...
Evaluation of Styplon in prevention of excessive bleeding in
Evaluation of Styplon in prevention of excessive bleeding in

... This study was carried out in the Department of Otolaryngology of Civil Hospital, Satara. Hundred cases of either sex of various age groups in whom tonsillectomy was indicated were selected for the present studies. They were divided into two groups i.e. control group (Group I) and Styplon Group (Gro ...
Drug Treatments - Osteoporosis Canada
Drug Treatments - Osteoporosis Canada

... to be at risk of osteoporosis or an osteoporosis related fracture, you may need a bone mineral density (BMD) test, the results of which are then incorporated into one of the new fracture risk assessment tools – CAROC or FRAX. This process allows your doctor to calculate your fracture risk. Fracture ...
RE-MODEL
RE-MODEL

... Adjust dosing to 150 mg daily dabigatran with amiodarone Pantoprazole Co-administration with Dabigatran may diminish clinical effect ...
New Antidotes in Toxicology
New Antidotes in Toxicology

...  IV NAC = oral NAC in efficacy  Best results when NAC is initiated within 8 hours post APAP ingestion  Preparation and delivery should be timely  Anaphylactoid reactions are rare with oral but occur with IV NAC ...
insomnia - BC Renal Agency
insomnia - BC Renal Agency

... the literature is lacking in patients with chronic kidney disease (CKD) and therefore treatment recommendations are extrapolated from the general population. In addition, most studies assess shortterm treatment of insomnia and not the chronic issue faced by CKD patients. ...
History of anticoagulant therapy
History of anticoagulant therapy

... Cost per month of oral anticoagulants • Rivaroxaban (20 mg/day) : $290 • Dabigatran (150 mg bid): $290 • Apixaban (5 mg bid): $147 ...
see Section 3.1 - Doncaster and Bassetlaw Hospitals NHS
see Section 3.1 - Doncaster and Bassetlaw Hospitals NHS

...  All patients with symptomatic asthma should be prescribed an inhaled short-acting β2 agonist as short-term reliever therapy. As required use is at least as good as regular (four times daily) use. Salbutamol is the first-line short-acting β2 agonist  Heavy or increasing use of β2 agonist therapy i ...
Alternative and complementary therapies for the
Alternative and complementary therapies for the

... inhibitors (SSRIs), many of these studies being related to breast cancer patients. Of the herbal medicinal products, the largest evidence base rests with phytoestrogens. A Cochrane Database review looking at all types of phytoestrogens, e.g. red clover extracts, dietary soya and soya extracts conclu ...
PR BEZALIP SR
PR BEZALIP SR

... Due to the risk of rhabdomyolysis, bezafibrate should only be administered together with HMG CoA reductase inhibitors in exceptional cases when strictly indicated. Patients receiving this combination therapy must be informed carefully of the symptoms of myopathy and monitored closely. Combination th ...
Aldosterone Antagonists
Aldosterone Antagonists

... Spironolactone may be used in patients with NYHA III‐IV heart failure on optimal medical therapy, while Eplerenone  has shown benefit in patients with NYHA II symptoms.   Patients should be on maximum medical therapy including ACE/ARB and Beta Blocker prior to initiation of an  aldosterone antagonis ...
This is the English version of the scientific brochure for Remifemin in
This is the English version of the scientific brochure for Remifemin in

... especially in overweight, obese women elevated hormone levels are detected and in comparison to women with lower body weight they have a clearly smaller risk of osteoporosis. The climacteric phase of a woman is characterized by typical hormonal changes predominated by a reduction of the 17-βestradio ...
Package Insert - Merck Animal Health
Package Insert - Merck Animal Health

... adult Beagles at doses of 7.5 mg/kg, 22.5 mg/kg, and 37.5 mg/kg once daily for 30 consecutive days, and at 75 mg/kg/day once daily for 10 consecutive days. Body temperature, respiratory rate and heart rate were not affected by orbifloxacin treatment. Discoloration of the feces (white to yellow) was o ...
Sildenafil as a Substitute for Subcutaneous Prostacyclin in
Sildenafil as a Substitute for Subcutaneous Prostacyclin in

... A 25-year old woman with SLE was diagnosed with PHT with no response to a vasoreactivity test with epoprostenol. The patient suffered repeated effort-related syncopes once treatment with inhaled prostacyclin began. For this reason treatment with subcutaneous prostacyclin, at a dose of up to 15 ng/kg ...
Non commercial use only - Italian Journal of Medicine
Non commercial use only - Italian Journal of Medicine

... should be investigated in more depth. A dependent prolongation of PT, dilute PT, and aPTT was observed with rivaroxaban. Results may vary depending on the reagents used and this variation cannot be standardized with the INR system commonly used for vitamin K antagonists. So, results of the PT-test c ...
Endocrine aspects of anabolic steroids
Endocrine aspects of anabolic steroids

... dose–response relationships of androgen action The rationale of using anabolic steroids in competitive sports is based on the following considerations: (a) the clear differential in athletic performance between males and females, on average, the lean body mass being 30% higher in men than in women; ...
SYNACTHEN® DEPOT 1 mg/mL
SYNACTHEN® DEPOT 1 mg/mL

... There is a limited amount of data on the use of Synacthen in pregnant patients. Data from animal studies are insufficient with respect to reproductive toxicity/teratogenicity. Synacthen should be used during pregnancy only if the expected benefit outweighs the potential risk to the fetus. Breast-fee ...
L3_protein synthesis..
L3_protein synthesis..

...  Because aminoglycosides are concentration- and timedependent and also have post antibiotic effect, once-daily dosing with the aminoglycosides can be employed. This results in less toxicity and less expensive to administer.  They have limited tissue penetration and do not pass the BBB.  Glomerula ...
Read the updated advice - Association of Paediatric Anaesthetists
Read the updated advice - Association of Paediatric Anaesthetists

... discharge  may  not  be  followed  by  parents  or  carers.  Inadequate  dosing  may  result  in   avoidable  pain  while  excess  dosing  risks  adverse  events  that  include  respiratory  depression   or  even  respiratory  arrest.  All ...
Dewormer Chart for Goats
Dewormer Chart for Goats

... guideline  for  anthelmintic  (deworming)  dosages  for  goats.    Producers  should  always  consult  their  veterinarian  for   advice  on  their  specific  management  situation,  for  determining  which  of  the  dewormers  remain  effectiv ...
Appendix 9: Drugs used in ASD
Appendix 9: Drugs used in ASD

... (Appendix 9 of: Ministries of Health and Education. 2008. New Zealand Autism Spectrum Disorder Guideline Wellington: Ministry of Health) ...
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Dydrogesterone



Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.
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