Japanese Journal of Ophthalmology Vol.42 No.2
... made available for clinical use, demonstrated that either drug given twice a day effectively reduces IOP in monkey eyes made glaucomatous by repeat argon laser trabeculoplasty. Intraocular pressure was reduced 1 hour after the initial dose of either drug. Latanoprost had a longer duration of effect ...
... made available for clinical use, demonstrated that either drug given twice a day effectively reduces IOP in monkey eyes made glaucomatous by repeat argon laser trabeculoplasty. Intraocular pressure was reduced 1 hour after the initial dose of either drug. Latanoprost had a longer duration of effect ...
Mental Health Medications CE for Pharmacy Technicians
... LCDR, United States Public Health Service Alaska Native Medical Center Mediset Pharmacy ...
... LCDR, United States Public Health Service Alaska Native Medical Center Mediset Pharmacy ...
ROPINIROLE-GA PRODUCT INFORMATION (ropinirole) NAME OF
... mg/kg/day and fetal malformations (predominantly digital malformations) at 120 mg/kg/day. There was no teratogenic effect in rats at 90 mg/kg/day and no indication of an effect on fetal development in rabbits at 20 mg/kg/day. In rabbits, ropinirole on combination with levodopa (10/250 mg/kg/day) inc ...
... mg/kg/day and fetal malformations (predominantly digital malformations) at 120 mg/kg/day. There was no teratogenic effect in rats at 90 mg/kg/day and no indication of an effect on fetal development in rabbits at 20 mg/kg/day. In rabbits, ropinirole on combination with levodopa (10/250 mg/kg/day) inc ...
Sulodexide - Wiley Online Library
... observed in the kidney, liver and endothelium of veins and arteries (21,67). The pharmacokinetics in man has been evaluated using deuterium-labeled sulodexide (12). A single 100 mg dose of deuterated sulodexide was administered to healthy volunteers intravenously or orally. After intravenous dosage ...
... observed in the kidney, liver and endothelium of veins and arteries (21,67). The pharmacokinetics in man has been evaluated using deuterium-labeled sulodexide (12). A single 100 mg dose of deuterated sulodexide was administered to healthy volunteers intravenously or orally. After intravenous dosage ...
EA QA198.5.ErythromycinProkinetic
... a low-bulk diet. Of the 25 patients, 18 had short-term follow-up, 18 had long-term follow-up, and 14 had both. On short-term follow-up, 15 patients experienced some or dramatic improvement, while 3 experienced worsening or no change in symptoms (p=0.005). Mean duration of long-term use was 11±7 mont ...
... a low-bulk diet. Of the 25 patients, 18 had short-term follow-up, 18 had long-term follow-up, and 14 had both. On short-term follow-up, 15 patients experienced some or dramatic improvement, while 3 experienced worsening or no change in symptoms (p=0.005). Mean duration of long-term use was 11±7 mont ...
product monograph - Ask Novartis Pharma
... occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast, the N-terminal 24 amino-acid sequence is common to all species and is relatively non-antigenic, and it is only these amino-ac ...
... occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast, the N-terminal 24 amino-acid sequence is common to all species and is relatively non-antigenic, and it is only these amino-ac ...
Chemmart® ALPRAZOLAM TABLETS
... Effects on Ability to Drive and Use of Machines As with all patients taking central nervous system (CNS)-depressant medication, patients receiving alprazolam should be warned not to operate dangerous machinery or motor vehicles until it is known that they do not become drowsy or dizzy from alprazola ...
... Effects on Ability to Drive and Use of Machines As with all patients taking central nervous system (CNS)-depressant medication, patients receiving alprazolam should be warned not to operate dangerous machinery or motor vehicles until it is known that they do not become drowsy or dizzy from alprazola ...
(Avinza): prescribing information
... Morphine, a pure opioid agonist, is relatively selective for the mu receptor, although it can interact with other opioid receptors at higher doses. In addition to analgesia, the widely diverse effects of morphine include drowsiness, changes in mood, respiratory depression, decreased gastrointestinal ...
... Morphine, a pure opioid agonist, is relatively selective for the mu receptor, although it can interact with other opioid receptors at higher doses. In addition to analgesia, the widely diverse effects of morphine include drowsiness, changes in mood, respiratory depression, decreased gastrointestinal ...
Pharmacokinetics and pharmacodynamics of the - e
... the pharmacokinetic parameters is shown in Table 3. The AUC24 after a 200 mg oral dose is 45 mg·h/L and the equivalent AUC0–1 is about 70 mg·h/L.47,48 After a 200 mg iv dose, the AUC0–1 were 70–86 mg·h/L.50 There is little known on doselinearity with minocycline or the effect of multiple dosing on ...
... the pharmacokinetic parameters is shown in Table 3. The AUC24 after a 200 mg oral dose is 45 mg·h/L and the equivalent AUC0–1 is about 70 mg·h/L.47,48 After a 200 mg iv dose, the AUC0–1 were 70–86 mg·h/L.50 There is little known on doselinearity with minocycline or the effect of multiple dosing on ...
Estimating the “First in human” dose – a revisit with particular
... ADMET & DMPK 1(4) (2013) 63-75; doi: 10.5599/admet.1.4.10 ...
... ADMET & DMPK 1(4) (2013) 63-75; doi: 10.5599/admet.1.4.10 ...
Efficacy and tolerability of the new antiepileptic drugs II: Treatment of
... antiseizure drugs. However, we chose to use the term antiepileptic drugs, given its widespread use among all clinicians. ...
... antiseizure drugs. However, we chose to use the term antiepileptic drugs, given its widespread use among all clinicians. ...
Anecortave acetate in the treatment of age
... Abstract: RETAANE® 15mg (anecortave acetate suspension) is under investigation to treat exudative age-related macular degeneration (AMD), the single largest cause of blindness in the Western world, affecting over 15 million people in the USA. RETAANE suspension is a unique synthetic cortisene and ha ...
... Abstract: RETAANE® 15mg (anecortave acetate suspension) is under investigation to treat exudative age-related macular degeneration (AMD), the single largest cause of blindness in the Western world, affecting over 15 million people in the USA. RETAANE suspension is a unique synthetic cortisene and ha ...
Synergistic Effect of the Ethanol Extract of Alismatis rhizoma against
... compounds and has increasingly attracted the attention of researchers [17]. Alismatis rhizoma or Alisma orientale (Zexie in Chinese), the dried rhizome of Alisma orientale Juzepzuk (Alismataceae), is known to have diuretic and damp-heat clearing actions and has been used for the treatment of dysuria ...
... compounds and has increasingly attracted the attention of researchers [17]. Alismatis rhizoma or Alisma orientale (Zexie in Chinese), the dried rhizome of Alisma orientale Juzepzuk (Alismataceae), is known to have diuretic and damp-heat clearing actions and has been used for the treatment of dysuria ...
PDR - Seroquel Tablets
... mainly via hepatic metabolism with a mean terminal half-life of about 6 hours within the proposed clinical dose range. Steady-state concentrations are expected to be achieved within two days of dosing. Quetiapine is unlikely to interfere with the metabolism of drugs metabolized by cytochrome P450 en ...
... mainly via hepatic metabolism with a mean terminal half-life of about 6 hours within the proposed clinical dose range. Steady-state concentrations are expected to be achieved within two days of dosing. Quetiapine is unlikely to interfere with the metabolism of drugs metabolized by cytochrome P450 en ...
A study with cumulative doses of formoterol and salbutamol in
... reported or observed after formoterol, except for one report of slight headache and tiredness. There were no significant differences in bronchodilating effect or systemic effects between formoterol in the cumulative doses of 6, 18, and 54 ~!g (total 78 !l8) and salbutamol 100, 300 and 900 1!8 (total ...
... reported or observed after formoterol, except for one report of slight headache and tiredness. There were no significant differences in bronchodilating effect or systemic effects between formoterol in the cumulative doses of 6, 18, and 54 ~!g (total 78 !l8) and salbutamol 100, 300 and 900 1!8 (total ...
Note for Guidance on Pk in renal impairment
... sufficient to measure protein binding at one or two timepoints post-dose and use this unbound fraction in calculation of unbound exposure. An alternative could be an assessment of the effect of pre-dialysis plasma (plasma taken from a dialysis patient shortly before dialysis) on plasma protein bindi ...
... sufficient to measure protein binding at one or two timepoints post-dose and use this unbound fraction in calculation of unbound exposure. An alternative could be an assessment of the effect of pre-dialysis plasma (plasma taken from a dialysis patient shortly before dialysis) on plasma protein bindi ...
Choose the Only FDA-approved Hyaluronidase
... When considering the administration of any other drug with HYLENEX recombinant is contraindicated in patients with hyaluronidase, it is recommended that appropriate references known hypersensitivity to hyaluronidase or any of the first be consulted to determine the usual precautions for the excipien ...
... When considering the administration of any other drug with HYLENEX recombinant is contraindicated in patients with hyaluronidase, it is recommended that appropriate references known hypersensitivity to hyaluronidase or any of the first be consulted to determine the usual precautions for the excipien ...
2017 Medicare Reimbursement Information
... billing unit. The vial contains more than one mL and less than two mLs, therefore there are two units per vial. When reporting drug units providers round up to the next whole unit when a unit of measure is exceeded. Category lll codes such as 0399T and 0439T are contractor priced by Medicare under t ...
... billing unit. The vial contains more than one mL and less than two mLs, therefore there are two units per vial. When reporting drug units providers round up to the next whole unit when a unit of measure is exceeded. Category lll codes such as 0399T and 0439T are contractor priced by Medicare under t ...
July 2014 - Positive Recommendations (Word 79KB)
... dapagliflozin/metformin XR FDC for the treatment of Type II diabetes on a cost-minimisation basis with dapagliflozin and metformin IR. The equieffective doses of dapagliflozin/metformin XR FDC are the corresponding doses of dapagliflozin and metformin IR. The PBAC recommended, as proposed by the spo ...
... dapagliflozin/metformin XR FDC for the treatment of Type II diabetes on a cost-minimisation basis with dapagliflozin and metformin IR. The equieffective doses of dapagliflozin/metformin XR FDC are the corresponding doses of dapagliflozin and metformin IR. The PBAC recommended, as proposed by the spo ...
PRODUCT INFORMATION ISOPTIN INJECTION SOLUTION
... Because of the drug’s negative inotropic effect, verapamil should not be used in patients with poorly compensated congestive heart failure, unless the failure is complicated by or caused by an arrhythmia. If verapamil is used in such patients, they must be digitalized prior to treatment. Continuous ...
... Because of the drug’s negative inotropic effect, verapamil should not be used in patients with poorly compensated congestive heart failure, unless the failure is complicated by or caused by an arrhythmia. If verapamil is used in such patients, they must be digitalized prior to treatment. Continuous ...
Marie-Chantal Bonhomme1, Nadia Cardillo Marricco1
... reducing cardiovascular morbidity and mortality; treatment of renal disease; and treatment of symptomatic heart failure. The recommended initial dose of ramipril is usually of 2.5 mg administered once daily. The dose adjustment and maintenance dose vary upon indication and ranges from 2.5 to 10 mg p ...
... reducing cardiovascular morbidity and mortality; treatment of renal disease; and treatment of symptomatic heart failure. The recommended initial dose of ramipril is usually of 2.5 mg administered once daily. The dose adjustment and maintenance dose vary upon indication and ranges from 2.5 to 10 mg p ...
Full Prescribing Information
... symptoms and some of the central-nervous-system manifestations. Adults suspected of contact with organic phosphorus insecticides of the parathion type should be given atropine sulfate, 0.8 mg, intramuscularly. If an atropine effect is not apparent within thirty minutes or if definite symptoms of the ...
... symptoms and some of the central-nervous-system manifestations. Adults suspected of contact with organic phosphorus insecticides of the parathion type should be given atropine sulfate, 0.8 mg, intramuscularly. If an atropine effect is not apparent within thirty minutes or if definite symptoms of the ...
Rational Selection of Antimicrobials for Use in Horses
... adjunctive role in the therapeutic management of horses and foals with a variety of illnesses, including those requiring critical care, because diseases caused by primary or secondary bacterial infection are commonly encountered and may contribute to failure of single or multiple organs. However, it ...
... adjunctive role in the therapeutic management of horses and foals with a variety of illnesses, including those requiring critical care, because diseases caused by primary or secondary bacterial infection are commonly encountered and may contribute to failure of single or multiple organs. However, it ...
AusPAR: Ruxolitinib - Therapeutic Goods Administration
... was 95% or greater.” No absolute bioavailability study was undertaken and no human intravenous dosing. In Study18424-134 single 25 mg oral solution doses of radiolabelled (14C)-ruxolitinib were given to healthy subjects. Mean total recovery of radioactivity was 96%, with essentially all the administ ...
... was 95% or greater.” No absolute bioavailability study was undertaken and no human intravenous dosing. In Study18424-134 single 25 mg oral solution doses of radiolabelled (14C)-ruxolitinib were given to healthy subjects. Mean total recovery of radioactivity was 96%, with essentially all the administ ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.