HICON® Kit for the Preparation of Sodium Iodide I 131
... HICON® is contraindicated in pregnancy because sodium iodide I 131 crosses the placenta and fetal exposure can lead to neonatal hypothyroidism. Multiple reports in the published literature describe hypothyroidism in the neonates following in utero exposure to sodium iodide I 131. Some cases of neona ...
... HICON® is contraindicated in pregnancy because sodium iodide I 131 crosses the placenta and fetal exposure can lead to neonatal hypothyroidism. Multiple reports in the published literature describe hypothyroidism in the neonates following in utero exposure to sodium iodide I 131. Some cases of neona ...
Lidocaine HCI 2% and Epinephrine 1:50,000 Injection Lidocaine
... especially during early pregnancy when maximum organogenesis takes place. Nursing mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when lidocaine is administered to a nursing woman. Pediatric use Dosages i ...
... especially during early pregnancy when maximum organogenesis takes place. Nursing mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when lidocaine is administered to a nursing woman. Pediatric use Dosages i ...
Annual Monitoring for Patients on Persistent Medications
... found that for all adverse drug events, the increase in post-event costs over the preevent period was $1,310 greater for those experiencing an adverse drug event than a comparison group, after controlling for age, sex, comorbidity, number of scheduled medications and hospitalization during the pre-e ...
... found that for all adverse drug events, the increase in post-event costs over the preevent period was $1,310 greater for those experiencing an adverse drug event than a comparison group, after controlling for age, sex, comorbidity, number of scheduled medications and hospitalization during the pre-e ...
How to use the BNF - NHS Education for Scotland
... In 2015 the BNF underwent a fundamental change in structure in order to create purpose-designed digital products. These digital products build on longstanding existing products and sit alongside the familiar print BNF publications. The redesign of all formats makes the highly valued content in the B ...
... In 2015 the BNF underwent a fundamental change in structure in order to create purpose-designed digital products. These digital products build on longstanding existing products and sit alongside the familiar print BNF publications. The redesign of all formats makes the highly valued content in the B ...
Trental (pentoxifylline)
... Antihypertensive agents: Trental (pentoxifylline) may potentiate the action of antihypertensive agents. Patients receiving these agents require blood pressure monitoring and possibly a dose reduction of the antihypertensive agents. Anticoagulants: There have been reports of bleeding and/or prolonged ...
... Antihypertensive agents: Trental (pentoxifylline) may potentiate the action of antihypertensive agents. Patients receiving these agents require blood pressure monitoring and possibly a dose reduction of the antihypertensive agents. Anticoagulants: There have been reports of bleeding and/or prolonged ...
highlights of prescribing information
... pigmentation changes, application site scarring, herpes zoster, chemical conjunctivitis, and corneal burn. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug e ...
... pigmentation changes, application site scarring, herpes zoster, chemical conjunctivitis, and corneal burn. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug e ...
Zentel - FiloBase
... Absorption: Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g) ...
... Absorption: Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g) ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These
... Hypoglycemia is the most common adverse reaction associated with insulin containing products, including SOLIQUA 100/33 [see Adverse Reactions (6.1)]. Severe hypoglycemia can cause seizures, may be life-threatening or cause death. Hypoglycemia can impair concentration ability and reaction time; this ...
... Hypoglycemia is the most common adverse reaction associated with insulin containing products, including SOLIQUA 100/33 [see Adverse Reactions (6.1)]. Severe hypoglycemia can cause seizures, may be life-threatening or cause death. Hypoglycemia can impair concentration ability and reaction time; this ...
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------------CONTRAINDICATIONS-------------------------------
... reported with the use of nucleoside analogues alone or in combination, including didanosine and other antiretrovirals. A majority of these cases have been in women. Obesity and prolonged nucleoside exposure may be risk factors. Fatal lactic acidosis has been reported in pregnant women who received t ...
... reported with the use of nucleoside analogues alone or in combination, including didanosine and other antiretrovirals. A majority of these cases have been in women. Obesity and prolonged nucleoside exposure may be risk factors. Fatal lactic acidosis has been reported in pregnant women who received t ...
Treatment and Complications of Orbito-zygomatic Fractures
... ABSTRACT: The aim of the present study was to analyze the etiology, type and treatment employed in the orbitozygomatic fractures (OZ). Also, postoperative complications are described and correlated with the type of treatment used. Fifty patients with OZ fractures were evaluated. Orbital fractures in ...
... ABSTRACT: The aim of the present study was to analyze the etiology, type and treatment employed in the orbitozygomatic fractures (OZ). Also, postoperative complications are described and correlated with the type of treatment used. Fifty patients with OZ fractures were evaluated. Orbital fractures in ...
nw-qa143-5-glucosamine-adverse
... studied. Until further information becomes available, it is suggested that patients with diabetes should monitor their blood glucose levels more closely when glucosamine is initiated, the dose is increased or the product being taken is changed (11, 12, 13, 14, 16). Liver toxicity There are a few pub ...
... studied. Until further information becomes available, it is suggested that patients with diabetes should monitor their blood glucose levels more closely when glucosamine is initiated, the dose is increased or the product being taken is changed (11, 12, 13, 14, 16). Liver toxicity There are a few pub ...
SINAREST Tablet/Syrup
... In case a hypersensitivity reaction occurs which is rare, SINAREST Tablet/Syrup should be discontinued. SINAREST Tablet/Syrup contains Paracetamol and therefore should not be used in conjunction with other Paracetamol containing products. SINAREST Tablet/Syrup should be used with caution in patients ...
... In case a hypersensitivity reaction occurs which is rare, SINAREST Tablet/Syrup should be discontinued. SINAREST Tablet/Syrup contains Paracetamol and therefore should not be used in conjunction with other Paracetamol containing products. SINAREST Tablet/Syrup should be used with caution in patients ...
Core Safety Profile Flecainide
... Treatment for patients with other indications should continue to be initiated in hospital. Intravenous treatment with flecainide should be initiated in hospital. Continuous ECG monitoring is recommended in all patients receiving bolus injection. Flecainide prolongs the QT interval and widens the QRS ...
... Treatment for patients with other indications should continue to be initiated in hospital. Intravenous treatment with flecainide should be initiated in hospital. Continuous ECG monitoring is recommended in all patients receiving bolus injection. Flecainide prolongs the QT interval and widens the QRS ...
description clinical pharmacology
... region, bilateral dislocated hips, and bilateral talipes equinovarus. The father was on long-term azathioprine therapy.16 Benefit versus risk must be weighed carefully before use of azathioprine in patients of reproductive potential. There are no adequate and well-controlled studies in pregnant wome ...
... region, bilateral dislocated hips, and bilateral talipes equinovarus. The father was on long-term azathioprine therapy.16 Benefit versus risk must be weighed carefully before use of azathioprine in patients of reproductive potential. There are no adequate and well-controlled studies in pregnant wome ...
Core Safety Profile Flecainide
... Treatment for patients with other indications should continue to be initiated in hospital. Intravenous treatment with flecainide should be initiated in hospital. Continuous ECG monitoring is recommended in all patients receiving bolus injection. Flecainide prolongs the QT interval and widens the QR ...
... Treatment for patients with other indications should continue to be initiated in hospital. Intravenous treatment with flecainide should be initiated in hospital. Continuous ECG monitoring is recommended in all patients receiving bolus injection. Flecainide prolongs the QT interval and widens the QR ...
NDA 18-936/S-064 Approved Labeling Enclosure Page 1 ENCLOSURE
... dosing was 9.3 days. Steady-state levels after prolonged dosing are similar to levels seen at 4 to 5 weeks. The long elimination half-lives of fluoxetine and norfluoxetine assure that, even when dosing is stopped, active drug substance will persist in the body for weeks (primarily depending on indiv ...
... dosing was 9.3 days. Steady-state levels after prolonged dosing are similar to levels seen at 4 to 5 weeks. The long elimination half-lives of fluoxetine and norfluoxetine assure that, even when dosing is stopped, active drug substance will persist in the body for weeks (primarily depending on indiv ...
Cabergoline Teva Pharma 2 mg tablet ENG
... not be concurrently administered with drugs that have dopamine-antagonist activity (such as phenothiazines, butyrophenones, thioxanthenes, metoclopramide) since these might reduce the therapeutic effect of cabergoline. As with other ergot derivatives, cabergoline should not be used in association wi ...
... not be concurrently administered with drugs that have dopamine-antagonist activity (such as phenothiazines, butyrophenones, thioxanthenes, metoclopramide) since these might reduce the therapeutic effect of cabergoline. As with other ergot derivatives, cabergoline should not be used in association wi ...
These highlights do not include all the information needed
... (4%), 92% had a history of VT and/or VT/VF, 71% had coronary artery disease, and 68% had a prior myocardial infarction. The incidence of proarrhythmia in patients with less serious or benign arrhythmias, which include patients with an increase in frequency of PVCs, was 1.6%. Although most proarrhyth ...
... (4%), 92% had a history of VT and/or VT/VF, 71% had coronary artery disease, and 68% had a prior myocardial infarction. The incidence of proarrhythmia in patients with less serious or benign arrhythmias, which include patients with an increase in frequency of PVCs, was 1.6%. Although most proarrhyth ...
Lovenox /Loveonox HP (enoxaparin sodium solution)
... manufacturing process, molecular weight distribution, anti-Xa and anti-IIa activities, units and dosages. Special attention and compliance with instructions for use of each specific product is required during any change in treatment. Determination of anti-Xa levels in plasma is the only method avail ...
... manufacturing process, molecular weight distribution, anti-Xa and anti-IIa activities, units and dosages. Special attention and compliance with instructions for use of each specific product is required during any change in treatment. Determination of anti-Xa levels in plasma is the only method avail ...
CLINDOXYL GEL - Skin Therapy Letter
... antibacterial activity of this compound is presumably due to the release of active or freeCLINDOXYL Gel Prescribing Information ...
... antibacterial activity of this compound is presumably due to the release of active or freeCLINDOXYL Gel Prescribing Information ...
Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB
... non-tuberculous mycobacterial diseases and TB [22–29]. Due to the lack of available antibiotics to treat such difficult cases, linezolid is already used off-label to treat MDR-TB in several countries, despite the absence of randomised controlled clinical trials to assess efficacy, safety and tolerab ...
... non-tuberculous mycobacterial diseases and TB [22–29]. Due to the lack of available antibiotics to treat such difficult cases, linezolid is already used off-label to treat MDR-TB in several countries, despite the absence of randomised controlled clinical trials to assess efficacy, safety and tolerab ...
Nitro-Dur - Merck.com
... in subsequent generations, however, was attributed to increased interstitial cell tissue and aspermatogenesis in the high-dose males. In this three-generation study there was no clear evidence of teratogenicity. Pregnancy: Pregnancy Category C: Animal teratology studies have not been conducted with ...
... in subsequent generations, however, was attributed to increased interstitial cell tissue and aspermatogenesis in the high-dose males. In this three-generation study there was no clear evidence of teratogenicity. Pregnancy: Pregnancy Category C: Animal teratology studies have not been conducted with ...
Amlo
... administration. The volume of distribution is approximately 21 l/kg. The pKa of amlodipine is 8.6. In vitro studies have shown that amlodipine is bound to plasmatic proteins up to 97.5%. Metabolism/Elimination The plasma elimination half-life is about 35-50 hours. Steady-state plasma levels are reac ...
... administration. The volume of distribution is approximately 21 l/kg. The pKa of amlodipine is 8.6. In vitro studies have shown that amlodipine is bound to plasmatic proteins up to 97.5%. Metabolism/Elimination The plasma elimination half-life is about 35-50 hours. Steady-state plasma levels are reac ...
Buffered Pfizerpen
... tetracycline) may diminish the bactericidal effects of penicillins by slowing the rate of bacterial growth. Bactericidal agents work most effectively against the immature cell wall of rapidly proliferating microorganisms. This has been demonstrated in vitro; however, the clinical significance of thi ...
... tetracycline) may diminish the bactericidal effects of penicillins by slowing the rate of bacterial growth. Bactericidal agents work most effectively against the immature cell wall of rapidly proliferating microorganisms. This has been demonstrated in vitro; however, the clinical significance of thi ...
How to safely prescribe long-acting opioids Feature article
... Pure agonist opioids include morphine, oxycodone, fentanyl, hydromorphone, and oxymorphone, to name a few. The analgesic or adverse effects of these agents do not reach a ceiling, which means when the dose increases, there is generally an increase in the analgesic activity and potential for adverse ...
... Pure agonist opioids include morphine, oxycodone, fentanyl, hydromorphone, and oxymorphone, to name a few. The analgesic or adverse effects of these agents do not reach a ceiling, which means when the dose increases, there is generally an increase in the analgesic activity and potential for adverse ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.