summary of product characteristics
... CYP3A4 and which have a low therapeutic index should therefore be used with caution (e.g. carbamazepine, digoxin, terfenadine). ...
... CYP3A4 and which have a low therapeutic index should therefore be used with caution (e.g. carbamazepine, digoxin, terfenadine). ...
Methadone Maintenance A Practical Guide to Pharmacotherapy
... • Each dose will have a greater effect until steady-state is achieved (potential for accumulated toxicity) • Methadone induction is a dangerous period for risk of overdose Most programs recommend at least 5 days between dose adjustments in the range of 5–10 mg. More rapid dose escalations could be a ...
... • Each dose will have a greater effect until steady-state is achieved (potential for accumulated toxicity) • Methadone induction is a dangerous period for risk of overdose Most programs recommend at least 5 days between dose adjustments in the range of 5–10 mg. More rapid dose escalations could be a ...
Dyslipemia are not associated with m-TOR, raptor or - HAL
... SRL introduction, at the time of SRL introduction and at different time-points postintroduction, as described above. Random effects were included on both the baseline value (before SRL introduction; intercept) and the different following visits (slope). Time independent covariates (age at the inclus ...
... SRL introduction, at the time of SRL introduction and at different time-points postintroduction, as described above. Random effects were included on both the baseline value (before SRL introduction; intercept) and the different following visits (slope). Time independent covariates (age at the inclus ...
full prescribing information
... 2% should receive the following information and instructions: 1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes, nose, mouth, and all mucous membranes. 2. This medication should not be used for any disorder other than that for whi ...
... 2% should receive the following information and instructions: 1. This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes, nose, mouth, and all mucous membranes. 2. This medication should not be used for any disorder other than that for whi ...
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------ WARNINGS and PRECAUTIONS ------------------------
... PHYSICIAN DURING UP-TITRATION. Prior to initiation of COREG, it is recommended that fluid retention be minimized. The recommended starting dose of COREG is 3.125 mg twice daily for 2 weeks. If tolerated, patients may have their dose increased to 6.25, 12.5, and 25 mg twice daily over successive inte ...
... PHYSICIAN DURING UP-TITRATION. Prior to initiation of COREG, it is recommended that fluid retention be minimized. The recommended starting dose of COREG is 3.125 mg twice daily for 2 weeks. If tolerated, patients may have their dose increased to 6.25, 12.5, and 25 mg twice daily over successive inte ...
Coreg - GSK Source
... In clinical trials of primarily mild-to-moderate heart failure, hypotension and postural hypotension occurred in 9.7% and syncope in 3.4% of subjects receiving COREG compared with 3.6% and 2.5% of placebo subjects, respectively. The risk for these events was highest during the first 30 days of dosin ...
... In clinical trials of primarily mild-to-moderate heart failure, hypotension and postural hypotension occurred in 9.7% and syncope in 3.4% of subjects receiving COREG compared with 3.6% and 2.5% of placebo subjects, respectively. The risk for these events was highest during the first 30 days of dosin ...
Systemic Therapy for Rosacea
... implicated in the development of lupus-like syndromes and hypersensitivity reactions. Of world-wide importance is the concern regarding emerging antibiotic resistance due to over/ misuse of antibiotics. Anti-inflammatory dose doxycycline (20mg doxycycline hyclate) was FDA approved in 1998 for the tr ...
... implicated in the development of lupus-like syndromes and hypersensitivity reactions. Of world-wide importance is the concern regarding emerging antibiotic resistance due to over/ misuse of antibiotics. Anti-inflammatory dose doxycycline (20mg doxycycline hyclate) was FDA approved in 1998 for the tr ...
IV-phenytoin-in-SE-version 3.1 final
... increase in the steady state plasma concentration. So unlike, for example, gentamicin where a 25% increase in the dose would result in an increase of 25% in the steady state concentration, a similar increase in a phenytoin dose could lead to a much larger, disproportionate increase in the steady sta ...
... increase in the steady state plasma concentration. So unlike, for example, gentamicin where a 25% increase in the dose would result in an increase of 25% in the steady state concentration, a similar increase in a phenytoin dose could lead to a much larger, disproportionate increase in the steady sta ...
here - Specialist Pharmacy Service
... increase in the steady state plasma concentration. So unlike, for example, gentamicin where a 25% increase in the dose would result in an increase of 25% in the steady state concentration, a similar increase in a phenytoin dose could lead to a much larger, disproportionate increase in the steady sta ...
... increase in the steady state plasma concentration. So unlike, for example, gentamicin where a 25% increase in the dose would result in an increase of 25% in the steady state concentration, a similar increase in a phenytoin dose could lead to a much larger, disproportionate increase in the steady sta ...
Anticoagulation Related Bleeding
... At higher doses, protamine sulphate may have significant anticoagulant and antiplatelet effects Anticoagulation Related Bleeding - Guideline Summary ...
... At higher doses, protamine sulphate may have significant anticoagulant and antiplatelet effects Anticoagulation Related Bleeding - Guideline Summary ...
here - Farmavita.Net
... Teratogenic effects: Pregnancy Category C. Isoniazid has been shown to have an embryocidal effect in rats and rabbits when given orally during pregnancy. Isoniazid was not teratogenic in reproduction studies in mice, rats and rabbits. There are no adequate and well-controlled studies in pregnant wom ...
... Teratogenic effects: Pregnancy Category C. Isoniazid has been shown to have an embryocidal effect in rats and rabbits when given orally during pregnancy. Isoniazid was not teratogenic in reproduction studies in mice, rats and rabbits. There are no adequate and well-controlled studies in pregnant wom ...
TAMIFLU Product Monograph
... with first dosing. These events did not lead to patient discontinuation of study drug in the vast majority of instances. At the recommended dose of 75 mg twice daily, the most frequently reported adverse events that led to patient withdrawal were nausea and vomiting. In adult/adolescent phase III tr ...
... with first dosing. These events did not lead to patient discontinuation of study drug in the vast majority of instances. At the recommended dose of 75 mg twice daily, the most frequently reported adverse events that led to patient withdrawal were nausea and vomiting. In adult/adolescent phase III tr ...
Product Information: Nanoparticle albumin
... clearance of paclitaxel ranged from 13 to 30 L/h/m2 and the mean terminal half-life ranged from 13 to 27 hours in patients with metastatic breast cancer, advanced NSCLC, or other solid tumours. After a 30-minute infusion of 260 mg/m2 doses of ABRAXANE, the mean values for cumulative urinary recovery ...
... clearance of paclitaxel ranged from 13 to 30 L/h/m2 and the mean terminal half-life ranged from 13 to 27 hours in patients with metastatic breast cancer, advanced NSCLC, or other solid tumours. After a 30-minute infusion of 260 mg/m2 doses of ABRAXANE, the mean values for cumulative urinary recovery ...
CALAN - verapamil hydrochloride tablet, film coated G.D. Searle LLC ---------- CALAN®
... prolonged in the elderly. In healthy men, orally administered CALAN undergoes extensive metabolism in the liver. Twelve metabolites have been identified in plasma; all except norverapamil are present in trace amounts only. Norverapamil can reach steady-state plasma concentrations approximately equal ...
... prolonged in the elderly. In healthy men, orally administered CALAN undergoes extensive metabolism in the liver. Twelve metabolites have been identified in plasma; all except norverapamil are present in trace amounts only. Norverapamil can reach steady-state plasma concentrations approximately equal ...
Patient Profile For Larry Besloft
... explained that the Arthritis was all over his body and he was administered an injection, unknown, in his left shoulder, but no relief was realized. At this time Oxycodone + Acetaminophen both 5mg for pain throughout the day and 7.5mg at bedtime were ordered. Repeated laboratory tests were done to id ...
... explained that the Arthritis was all over his body and he was administered an injection, unknown, in his left shoulder, but no relief was realized. At this time Oxycodone + Acetaminophen both 5mg for pain throughout the day and 7.5mg at bedtime were ordered. Repeated laboratory tests were done to id ...
HIGHLIGHTS OF PRESCRIBING INFORMATION discontinuation (5.4, 9.2)
... Use in patients with depression: As with other sedative/hypnotic drugs, Ambien CR should be administered with caution to patients exhibiting signs or symptoms of depression. Suicidal tendencies may be present in such patients and protective measures may be required. Intentional overdosage is more co ...
... Use in patients with depression: As with other sedative/hypnotic drugs, Ambien CR should be administered with caution to patients exhibiting signs or symptoms of depression. Suicidal tendencies may be present in such patients and protective measures may be required. Intentional overdosage is more co ...
Prescribing Information
... 6.2 Postmarketing Experience The following adverse reactions have been identified during post-approval use of FLOMAX capsules. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal re ...
... 6.2 Postmarketing Experience The following adverse reactions have been identified during post-approval use of FLOMAX capsules. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal re ...
PRODUCT MONOGRAPH PrMatulane® Procarbazine
... Therapy may be resumed, at the discretion of the physician, after toxic side effects have cleared on clinical evaluation and appropriate laboratory studies. Carcinogenesis and Mutagenesis Instances of new nonlymphoid malignancy, including lung cancer and acute myelocytic leukemia, have been reported ...
... Therapy may be resumed, at the discretion of the physician, after toxic side effects have cleared on clinical evaluation and appropriate laboratory studies. Carcinogenesis and Mutagenesis Instances of new nonlymphoid malignancy, including lung cancer and acute myelocytic leukemia, have been reported ...
Opioid Metabolism
... which drugs are broken down so that they can be eliminated by the body. Some drugs perform their functions and then are excreted from the body intact, but many require metabolism to enable them to reach their target site in an appropriate amount of time, remain there an adequate time, and then be el ...
... which drugs are broken down so that they can be eliminated by the body. Some drugs perform their functions and then are excreted from the body intact, but many require metabolism to enable them to reach their target site in an appropriate amount of time, remain there an adequate time, and then be el ...
Other adverse effects
... studied. Until further information becomes available, it is suggested that patients with diabetes should monitor their blood glucose levels more closely when glucosamine is initiated, the dose is increased or the product being taken is changed (11, 12, 13, 14, 16). Liver toxicity There are a few pub ...
... studied. Until further information becomes available, it is suggested that patients with diabetes should monitor their blood glucose levels more closely when glucosamine is initiated, the dose is increased or the product being taken is changed (11, 12, 13, 14, 16). Liver toxicity There are a few pub ...
TAMIFLU Product Monograph
... with first dosing. These events did not lead to patient discontinuation of study drug in the vast majority of instances. At the recommended dose of 75 mg twice daily, the most frequently reported adverse events that led to patient withdrawal were nausea and vomiting. In adult/adolescent phase III tr ...
... with first dosing. These events did not lead to patient discontinuation of study drug in the vast majority of instances. At the recommended dose of 75 mg twice daily, the most frequently reported adverse events that led to patient withdrawal were nausea and vomiting. In adult/adolescent phase III tr ...
C11 Chemistry 151 Whitesell The Provisional Progress of
... this drug include small red skin lesions, irregular periods, dry skin, puffy face (from water retention) and high blood sugar. Additional infrequent side effects may cause severe conditions such as osteoporosis, diabetes, and Cushing’s Syndrome. Although severe, these conditions are very rare and un ...
... this drug include small red skin lesions, irregular periods, dry skin, puffy face (from water retention) and high blood sugar. Additional infrequent side effects may cause severe conditions such as osteoporosis, diabetes, and Cushing’s Syndrome. Although severe, these conditions are very rare and un ...
Elocom Cream, Ointment and Lotion Physicians` Prescribing
... use on large areas of damaged skin, in flexures and with polythene occlusion. If used in childhood, or on the face, occlusion should not be used. If used on the face, courses should be limited to 5 days and occlusion should not be used. Long term continuous therapy should be avoided in all patients ...
... use on large areas of damaged skin, in flexures and with polythene occlusion. If used in childhood, or on the face, occlusion should not be used. If used on the face, courses should be limited to 5 days and occlusion should not be used. Long term continuous therapy should be avoided in all patients ...
highlights of prescribing information
... Cardiovascular Thrombotic Events Clinical trials of several COX-2 selective and nonselective NSAIDs of up to three years duration have shown an increased risk of serious cardiovascular (CV) thrombotic events, including myocardial infarction (MI) and stroke, which can be fatal. Based on available dat ...
... Cardiovascular Thrombotic Events Clinical trials of several COX-2 selective and nonselective NSAIDs of up to three years duration have shown an increased risk of serious cardiovascular (CV) thrombotic events, including myocardial infarction (MI) and stroke, which can be fatal. Based on available dat ...
The Penicillins - Available Courses
... b. Extended spectrum towards gram negative bacteria. Activity towards Richmond-Sykes Class II, III, IV, and V b-lactamases. Some Gm – blactamases are not inhibited (Richmond-Sykes Type I). . c. Clavulanic acid has some weak antibacterial activity itself. Binds to PBP-2. Combination with amoxicillin ...
... b. Extended spectrum towards gram negative bacteria. Activity towards Richmond-Sykes Class II, III, IV, and V b-lactamases. Some Gm – blactamases are not inhibited (Richmond-Sykes Type I). . c. Clavulanic acid has some weak antibacterial activity itself. Binds to PBP-2. Combination with amoxicillin ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.