Dosage Calculations INTRODUCTION
... Pediatric patients, which include both infants and children, require special dosing that is adjusted for their body weight. A number of formulas have been used throughout the years to determine the best dose for pediatric patients, but the most commonly used method is stated as mg/kg of body weight. ...
... Pediatric patients, which include both infants and children, require special dosing that is adjusted for their body weight. A number of formulas have been used throughout the years to determine the best dose for pediatric patients, but the most commonly used method is stated as mg/kg of body weight. ...
analgesic nephropathy medical grand rounds william
... High and low NAPA groups were Identified based on the absolute amounts of NAPA In the urine; the high group was shown to Ingest greater than 1.25 g/d of phenacetin. An Initial study revealed that phenacetin consumers are more likely to have a history of proteinuria, kidney disorders, and abnormal co ...
... High and low NAPA groups were Identified based on the absolute amounts of NAPA In the urine; the high group was shown to Ingest greater than 1.25 g/d of phenacetin. An Initial study revealed that phenacetin consumers are more likely to have a history of proteinuria, kidney disorders, and abnormal co ...
KLONOPIN® TABLETS (clonazepam)
... dosages of 5 mg/kg/day or greater and reduction in embryo-fetal growth occurred in one study at a dosage of 10 mg/kg/day. No adverse maternal or embryo-fetal effects were observed in mice and rats following administration during organogenesis of oral doses up to 15 mg/kg/day or 40 mg/kg/day, respect ...
... dosages of 5 mg/kg/day or greater and reduction in embryo-fetal growth occurred in one study at a dosage of 10 mg/kg/day. No adverse maternal or embryo-fetal effects were observed in mice and rats following administration during organogenesis of oral doses up to 15 mg/kg/day or 40 mg/kg/day, respect ...
hydralazine hydrochloride USP
... Usage in Pregnancy Animal studies indicate that high doses of hydralazine are teratogenic in mice, possibly in rabbits, but not in rats (see TOXICOLOGY). Teratogenic effects observed were cleft palate and malformation of facial and cranial bones. There are no adequate and well-controlled studies in ...
... Usage in Pregnancy Animal studies indicate that high doses of hydralazine are teratogenic in mice, possibly in rabbits, but not in rats (see TOXICOLOGY). Teratogenic effects observed were cleft palate and malformation of facial and cranial bones. There are no adequate and well-controlled studies in ...
CYMBALTA (duloxetine hydrochloride) Delayed-release Capsules
... clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Cymbalta is not approved for use in pediatric patients. (See WARNINGS and PRECAUTIONS, Pediatric Use.) Pooled analyses o ...
... clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Cymbalta is not approved for use in pediatric patients. (See WARNINGS and PRECAUTIONS, Pediatric Use.) Pooled analyses o ...
Clinical Strategies for Selecting Oral Anticoagulants in Patients
... Elderly patients have a higher incidence of polypharmacy and renal impairment secondary to decreased creatinine clearance with age. The NOACs may provide a more attractive drug interaction profile with less impact on pharmacokinetics and pharmacodynamics for most patients with polypharmacy, as compa ...
... Elderly patients have a higher incidence of polypharmacy and renal impairment secondary to decreased creatinine clearance with age. The NOACs may provide a more attractive drug interaction profile with less impact on pharmacokinetics and pharmacodynamics for most patients with polypharmacy, as compa ...
micronor - Janssen
... frequency of having breast cancer diagnosed in women who are currently using oral contraceptives (OCs) or had used them within the past 10 years compared to never-users. Breast cancers diagnosed in ever-users tend to be less advanced clinically than the cancers diagnosed in never-users. Breast cance ...
... frequency of having breast cancer diagnosed in women who are currently using oral contraceptives (OCs) or had used them within the past 10 years compared to never-users. Breast cancers diagnosed in ever-users tend to be less advanced clinically than the cancers diagnosed in never-users. Breast cance ...
this smells. this doesn`t.
... unclothed application sites in men using testosterone gel. Healthcare providers should advise patients to strictly adhere to recommended instructions for use. Indication: Testosterone Gel 1% is used as a replacement therapy in adult males for conditions associated with a deficiency or absence of end ...
... unclothed application sites in men using testosterone gel. Healthcare providers should advise patients to strictly adhere to recommended instructions for use. Indication: Testosterone Gel 1% is used as a replacement therapy in adult males for conditions associated with a deficiency or absence of end ...
Use of Antithrombotics in Non-Valvular Atrial Fibrillation
... Atrial fibrillation (AF) is the most common cardiac arrhythmia, and is responsible for one-third of hospitalizations due to arrhythmia. Currently, AF affects 2.5 million people in the United States; however, this percentage is expected to increase to an estimated 16 million people by the year 2050, ...
... Atrial fibrillation (AF) is the most common cardiac arrhythmia, and is responsible for one-third of hospitalizations due to arrhythmia. Currently, AF affects 2.5 million people in the United States; however, this percentage is expected to increase to an estimated 16 million people by the year 2050, ...
S - Merck Animal Health
... EFFECTS OF OVEREXPOSURE: There has been no human use of this specific product. The information contained in this section is extrapolated from data available on other products of the same pharmacological class that have been used in humans. Effects anticipated are due to the progestational activity o ...
... EFFECTS OF OVEREXPOSURE: There has been no human use of this specific product. The information contained in this section is extrapolated from data available on other products of the same pharmacological class that have been used in humans. Effects anticipated are due to the progestational activity o ...
Ribavirin Dose Modification Based on Renal Function Is Necessary
... and John J. Fung* Hepatitis C virus (HCV) is currently the most common etiology for liver transplantation (LTx) in the United States. A significant number of patients develop recurrent HCV after LTx. Although there is no completely satisfactory treatment for recurrent HCV, a combination of interfero ...
... and John J. Fung* Hepatitis C virus (HCV) is currently the most common etiology for liver transplantation (LTx) in the United States. A significant number of patients develop recurrent HCV after LTx. Although there is no completely satisfactory treatment for recurrent HCV, a combination of interfero ...
IMITREX® Nasal Spray Tear Sheet
... were instructed to treat a moderate to severe headache. Headache response, defined as a reduction in headache severity from moderate or severe pain to mild or no pain, was assessed up to 2 hours after dosing. Associated symptoms such as nausea, photophobia, and phonophobia were also assessed. Mainte ...
... were instructed to treat a moderate to severe headache. Headache response, defined as a reduction in headache severity from moderate or severe pain to mild or no pain, was assessed up to 2 hours after dosing. Associated symptoms such as nausea, photophobia, and phonophobia were also assessed. Mainte ...
Comparison of High Loading Dose Versus Usual Dose of Rectal
... dose acetaminophen. After one hour, the frequency of patients who showed a 2°C decrease in their body temperature was not different in the two groups but this difference was significant three hours after treatment (P value = 0.05). The results of the studies by Howell and Patel (17) and Beck et al. ...
... dose acetaminophen. After one hour, the frequency of patients who showed a 2°C decrease in their body temperature was not different in the two groups but this difference was significant three hours after treatment (P value = 0.05). The results of the studies by Howell and Patel (17) and Beck et al. ...
Suggestion from clinicians
... “Domperidone and metoclopramide were equally effective in alleviating symptoms of diabetic gastroparesis. Elicited adverse CNS effects were more severe and more common with metoclopramide. Somnolence was acknowledged by 49% of patients (mean severity score, 1.03) after 4 wk of metoclopramide compare ...
... “Domperidone and metoclopramide were equally effective in alleviating symptoms of diabetic gastroparesis. Elicited adverse CNS effects were more severe and more common with metoclopramide. Somnolence was acknowledged by 49% of patients (mean severity score, 1.03) after 4 wk of metoclopramide compare ...
Zerit_1212_515US12PBS00101wip3.indd 1 1/3/13 1:24 PM
... with known risk factors for liver disease; however, cases of lactic acidosis have also been reported in patients with no known risk factors. Generalized fatigue, digestive symptoms (nausea, vomiting, abdominal pain, and unexplained weight loss); respiratory symptoms (tachypnea and dyspnea); or neuro ...
... with known risk factors for liver disease; however, cases of lactic acidosis have also been reported in patients with no known risk factors. Generalized fatigue, digestive symptoms (nausea, vomiting, abdominal pain, and unexplained weight loss); respiratory symptoms (tachypnea and dyspnea); or neuro ...
D F PHARMACOKINETICS AND INTRODUCTION
... relationships, and poor performance in school.1,2 In 2006 in the U.S., ADHD was diagnosed in about 4.5 million children 5 to 17 years of age.3 From 3% to 7% of school-aged children have ADHD. In some studies, estimated rates are higher in community samples.1 Stimulants constitute the first-line trea ...
... relationships, and poor performance in school.1,2 In 2006 in the U.S., ADHD was diagnosed in about 4.5 million children 5 to 17 years of age.3 From 3% to 7% of school-aged children have ADHD. In some studies, estimated rates are higher in community samples.1 Stimulants constitute the first-line trea ...
Captopril Tablets, USP 12.5 mg, 25 mg, 50 mg and 100 mg
... Neutropenia (<1000/mm3) with myeloid hypoplasia has resulted from use of captopril. About half of the neutropenic patients developed systemic or oral cavity infections or other features of the syndrome of agranulocytosis. The risk of neutropenia is dependent on the clinical status of the patient: In ...
... Neutropenia (<1000/mm3) with myeloid hypoplasia has resulted from use of captopril. About half of the neutropenic patients developed systemic or oral cavity infections or other features of the syndrome of agranulocytosis. The risk of neutropenia is dependent on the clinical status of the patient: In ...
sinemet - Merck.com
... should be performed by appropriately qualified individuals (e.g., dermatologists). Information for Patients The patient should be informed that SINEMET is an immediate-release formulation of carbidopa levodopa that is designed to begin release of ingredients within 30 minutes. It is important that S ...
... should be performed by appropriately qualified individuals (e.g., dermatologists). Information for Patients The patient should be informed that SINEMET is an immediate-release formulation of carbidopa levodopa that is designed to begin release of ingredients within 30 minutes. It is important that S ...
Update on treatment of hereditary angioedema Review article
... surgical abdominal emergency. There are reports that HAE can mimic acute appendicitis and it is not unusual that patients have multiple abdominal surgeries before the realization that the pain is HAE.15 Abdominal attacks can last for 1 to 8 days, causing significant morbidity. HAE can also be a caus ...
... surgical abdominal emergency. There are reports that HAE can mimic acute appendicitis and it is not unusual that patients have multiple abdominal surgeries before the realization that the pain is HAE.15 Abdominal attacks can last for 1 to 8 days, causing significant morbidity. HAE can also be a caus ...
Seizures
... anticonvulsant is started. □If the child is still experiencing more than one seizure per month, a second drug is added in combination. After a long period of control (a few months), the initial drug can be discontinued. a second single drug also belongs to monotherapy. ...
... anticonvulsant is started. □If the child is still experiencing more than one seizure per month, a second drug is added in combination. After a long period of control (a few months), the initial drug can be discontinued. a second single drug also belongs to monotherapy. ...
INSTILLAGEL
... plasma concentrations, with an increased risk for toxic symptoms, such as convulsions. PATIENTS SHOULD BE INSTRUCTED TO STRICTLY ADHERE TO THE RECOMMENDED DOSAGE. This is especially important in children where doses vary with weight. The management of serious adverse reactions may require the use of ...
... plasma concentrations, with an increased risk for toxic symptoms, such as convulsions. PATIENTS SHOULD BE INSTRUCTED TO STRICTLY ADHERE TO THE RECOMMENDED DOSAGE. This is especially important in children where doses vary with weight. The management of serious adverse reactions may require the use of ...
procainamide hcl
... Since Procainamide has short half – life (three hours) steadystate concentrations are achieved within 12 to 24 hours after therapy has begun . Although steady state is achieved quickly , the sampling time must be selected carefully within the dosing interval When standard dosage forms of Procainamid ...
... Since Procainamide has short half – life (three hours) steadystate concentrations are achieved within 12 to 24 hours after therapy has begun . Although steady state is achieved quickly , the sampling time must be selected carefully within the dosing interval When standard dosage forms of Procainamid ...
Abstract
... that topical NSAIDs can provide good levels of pain relief and that gastrointestinal adverse events are reduced compared with oral NSAIDs [16]. NSAIDs have also been combined with agents having gastroprotective effects into polypills that are currently available on the market. This strategy may incre ...
... that topical NSAIDs can provide good levels of pain relief and that gastrointestinal adverse events are reduced compared with oral NSAIDs [16]. NSAIDs have also been combined with agents having gastroprotective effects into polypills that are currently available on the market. This strategy may incre ...
Name of Medicine
... the previous levodopa dosage (see Dosage and Administration.) Dyskinesias may occur in patients previously treated with levodopa alone because carbidopa permits more levodopa to reach the brain and, thus, more dopamine to be formed. The occurrence of dyskinesias may require dosage reduction. As with ...
... the previous levodopa dosage (see Dosage and Administration.) Dyskinesias may occur in patients previously treated with levodopa alone because carbidopa permits more levodopa to reach the brain and, thus, more dopamine to be formed. The occurrence of dyskinesias may require dosage reduction. As with ...
Full Text - Int J Endocrinol Metab
... the vast majority of patients in this series (95.6%) received MMI. The majority of cases developed during the first few weeks of initiation of antithyroid therapy. Thionamideassociated agranulocytosis occurred irrespective of patient age and sex and duration of treatment. Low-dose methimazole seemed ...
... the vast majority of patients in this series (95.6%) received MMI. The majority of cases developed during the first few weeks of initiation of antithyroid therapy. Thionamideassociated agranulocytosis occurred irrespective of patient age and sex and duration of treatment. Low-dose methimazole seemed ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.