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HISTOLOGY

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Chimera (genetics)



A chimera (also spelled chimaera) (from the creature Chimera in Greek mythology) is a single organism composed of genetically distinct cells. This can result in male and female organs, two blood types, or subtle variations in form. Animal chimeras are produced by the merger of multiple fertilized eggs. In plant chimeras, however, the distinct types of tissue may originate from the same zygote, and the difference is often due to mutation during ordinary cell division. Normally, chimerism is not visible on casual inspection; however, it has been detected in the course of proving parentage.Another way that chimerism can occur in animals is by organ transplantation, giving one individual tissues that developed from two genomes. For example, a bone marrow transplant can change someone's blood type.
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