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Resonance-assignement-Structure-constraints
Resonance-assignement-Structure-constraints

... The receiver coil picks up the signal from the sample. An analog-to-digital converter “reads” the voltage and sends it to the computer for data storage. ...
Proteins and Enzymes
Proteins and Enzymes

... Evolution of proteins • Some pre-RNA polymer is believed to have come first; RNA evolved from that • RNA can function as enzymes • RNA became the template for DNA • Amino acids are attracted to codons • RNA catalyzed condensation of amino acids • Ribosomes evolved to increase efficiency and ...
Proteomic analyses of the time course responses of mice infected
Proteomic analyses of the time course responses of mice infected

... using MALDI-TOF MS. The results of the protein identification analysis are shown in Table 3. These data revealed that multiple immunogenic proteins at different locations on 2DE-immunoblotting showed diverse Mr and pI values and were correlated with theoretical values. Evidence of the subcellular lo ...
The proteasomal deubiquitinating enzyme POH1 promotes the
The proteasomal deubiquitinating enzyme POH1 promotes the

... and Molecular Genetics, King’s College London, Guy’s Hospital, London, UK, 3King’s College London Breakthrough Breast Cancer Unit, King’s College London, Guy’s Hospital, London, UK and 4Biomimetics and Biophotonics Research Group, Division of Cancer, King’s College London Dental Institute, London, U ...
sv-lncs - School of Mathematical and Computer Sciences
sv-lncs - School of Mathematical and Computer Sciences

... stage, once a node has been visited and added to the complex, it can not be added to another complex. [16] However, in the post-processing step, overlap is allowed to some extent. Because we here choose to go further by inspecting the interconnectedness, it is valuable to not only traverse the immed ...
The K-Segment of Maize DHN1 Mediates Binding
The K-Segment of Maize DHN1 Mediates Binding

... accumulate in the late stages of seed development and in vegetative tissues subjected to water deficit, salinity, low temperature, or abscisic acid treatment. We demonstrated previously that maize (Zea mays) DHNs bind preferentially to anionic phospholipid vesicles; this binding is accompanied by an ...
PROTEIN-LIPID AND PROTEIN-CARBOHYDRATE INTERACTIONS
PROTEIN-LIPID AND PROTEIN-CARBOHYDRATE INTERACTIONS

... effect but a result of specific interactions between lipids and given protein subunits. Good correlation was found between the polar lipid content and baking value of wheats resp. flours. The role of carbohydrates in the formation of gluten complex has not been investigated so thoroughly as the lipi ...
Microbial Degradation of Cycloparaffinic
Microbial Degradation of Cycloparaffinic

... unable to grow on propane, can utilize the cyclohexanone produced as a co-metabolic product from cyclohexane by JOB^. Since the only labelled substrate present was cyclohexane, these data show a definite enhancement of cycloparaffin degradation by microbial co-metabolism and commensalism. A similar ...
Microbial Degradation of Cycloparaffinic
Microbial Degradation of Cycloparaffinic

... unable to grow on propane, can utilize the cyclohexanone produced as a co-metabolic product from cyclohexane by JOB^. Since the only labelled substrate present was cyclohexane, these data show a definite enhancement of cycloparaffin degradation by microbial co-metabolism and commensalism. A similar ...
Srivastava, Sanjay: Analysis of Methods for Predicting Protein Fold and Remote Homologue Recognition
Srivastava, Sanjay: Analysis of Methods for Predicting Protein Fold and Remote Homologue Recognition

... (1D) involves the kind of fold that the given amino acid sequence may adopt. If similarity between two proteins is detectable at the sequence level, structural similarity can usually be assumed, because the 3D structures of proteins from the same family are more conserved than their primary sequence ...
Document
Document

... recognises the E1-ubquitin complex and transfers the complex to itself 3) E3 ubiquitin ligase enzyme binds the condemned protein substrate and an E2-ubiquitin complex thus allowing E2 to transfer the ubiquitin to the protein to be destroyed. This process is repeated multiple times. Poly-ubiquitinate ...
Protein Denaturation Studies Using the Pyris 6 DSC
Protein Denaturation Studies Using the Pyris 6 DSC

... instruments to study the thermal properties of proteins in aqueous solution is becoming increasingly more important. In an aqueous solution, proteins have specialized threedimensional structures that allows them to support specific biological functions. When heat is applied to the protein, this shap ...
Protein synthesis meets ABC ATPases: new roles for Rli1/ABCE1
Protein synthesis meets ABC ATPases: new roles for Rli1/ABCE1

... catalysed by several translation factors. The fundamental reactions of protein synthesis, such as mRNA decoding, peptide bond formation and tRNA translocation, follow the same basic principles in prokaryotes and eukaryotes. However, some steps are quite different and require a larger set of factors ...
Protein Targeting into the Complex Plastid of Cryptophytes
Protein Targeting into the Complex Plastid of Cryptophytes

... N-terminal bipartite topogenic signal (BTS), composed of a signal peptide at the N-terminus which is followed by a transit peptide. Furthermore, these topogenic signal regions needed to precede the mature part of a protein, which was determined by standard blast searches and protein databases. To ge ...
Structurally related TPR subunits contribute differently to the function
Structurally related TPR subunits contribute differently to the function

... to as Apc8/Cdc23) subunits constitute a group of structurally related proteins within the APC/C, all of which contain nine to ten copies of the tetratrico-peptide repeat (TPR) motifs in tandem arrays. The TPRs are repeats of 34 amino acid structural motifs with a consensus sequence restricted only t ...
Leukaemia Section del(11)(q23q23) MLL/CBL t(11;11)(q23;q23) MLL/CBL Atlas of Genetics and Cytogenetics
Leukaemia Section del(11)(q23q23) MLL/CBL t(11;11)(q23;q23) MLL/CBL Atlas of Genetics and Cytogenetics

... may acetylates H3 and H4 in the HOX area; a SET domain: methyltransferase; methylates H3, including histones in the HOX area for allowing chromatin to be open to transcription. MLL is cleaved by taspase 1 into 2 proteins before entering the nucleus: a p300/320 N-term protein called MLL-N, and a p180 ...
Cross-Presentation Proteases in MHC Class I Presentation and
Cross-Presentation Proteases in MHC Class I Presentation and

... The proteasome is a large barrel-shaped particle present in the cytosol and nucleus of all eukaryotic cells (3–5) that is responsible for degrading of a majority of cellular proteins (6) (Fig. 1). At its core is a 20S cylinder that is composed of two outer a rings and two inner b rings with a centra ...
Getting the message across: how do plant cells exchange
Getting the message across: how do plant cells exchange

... unfolding of proteins before their translocation through the PD pore [1]. Recently, HSP70 has emerged as a possible chaperone for trafficking endogenous MCs to PD [9]. HSP cognate 70 (HSPc70) chaperones isolated from PD-rich wall fractions and from Cucurbita phloem exudates were found to interact wi ...
Adaptive Silver Films for Detection of Antibody Binding
Adaptive Silver Films for Detection of Antibody Binding

... deposition of the protein. In our recent work, silver films fabricated at a certain range of evaporation parameters allow fine rearrangement of the nanostructure upon protein deposition.20 This restructuring forms cavity sites enclosed by two or more metal particles, which are typically optimal for ...
Full Text
Full Text

... 1992). In the present communication, we describe a simple, onestep procedureforpurificationof prosomes fromembryonicmaterials, and we present data on the synthesis and cytolocalization of these particles during development in the chick embryos, During early embryogenesis, prosome polypeptides are no ...
Linkage Novel Type of Antigen with an Isopeptide Peptide Splicing
Linkage Novel Type of Antigen with an Isopeptide Peptide Splicing

... The 20S catalytic chamber consists of four stacked heptameric rings and has an overall architecture of a(1–7)b(1–7)b(1–7)a(1–7). The two outer a rings regulate entry into the complex and provide anchor points for the attachment of 19S regulatory caps, whereas the actual catalytic activity resides wi ...
Drosophila ventral furrow morphogenesis: a
Drosophila ventral furrow morphogenesis: a

... stimulates the small GTPase, Rho, to exchange its bound GDP for GTP, thereby activating Rho. A dominant negative form of Rho also produces ventral furrow defects. In tissue culture cells, Rho has been shown to stimulate stress fiber formation (Hall, 1998). These results indicate that the actin cytos ...
Microtubule Assembly and Disassembly
Microtubule Assembly and Disassembly

... the Cc at the + end but lower than the Cc at the – end, microtubules can treadmill by adding subunits to one end and dissociating subunits for the opposite end. ...
Chlamydia pneumoniae CdsQ functions as a multi
Chlamydia pneumoniae CdsQ functions as a multi

... attachment to the host cell, the EB injects the T3S effector protein, translocated actin recruitment protein (TARP), which facilitates bacterial internalization into a plasma-membrane derived vacuole, known as an inclusion [17, 18]. Once within the inclusion, the EB undergoes a transformation, diffe ...
A High Yield Method for the Removal of Detergents from Low
A High Yield Method for the Removal of Detergents from Low

... samples processed without detergent. The method significantly removes detergents from very low concentrated protein or peptide samples and eliminates the interference by detergents with the peptide mass spectral profile. The advantage of this method is the speed (less than 15 minutes), efficient det ...
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Proteasome



Proteasomes are protein complexes inside all eukaryotes and archaea, and in some bacteria. The main function of the proteasome is to degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
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