
Lecture 2: The Spinal Cord
... The ratio of white matter to gray matter increases from caudal to rostral ...
... The ratio of white matter to gray matter increases from caudal to rostral ...
What Do Mirror Neurons Mean?
... from a behavioral point of view human infants for years heavily rely on interactions with their caregivers and with other individuals to learn how to cope with the world. This is an important difference between humans and other species that may play a major role in bootstrapping more sophisticated c ...
... from a behavioral point of view human infants for years heavily rely on interactions with their caregivers and with other individuals to learn how to cope with the world. This is an important difference between humans and other species that may play a major role in bootstrapping more sophisticated c ...
Chapter 2 ciccarelli
... What are the nervous system, neurons and nerves How neurons use neurotransmitters to communicate How brain and spinal cord interact Somatic and autonomic nervous systems Study of the brain and how it works Structures and functions of the bottom part of the brain Structures that control emotion, lear ...
... What are the nervous system, neurons and nerves How neurons use neurotransmitters to communicate How brain and spinal cord interact Somatic and autonomic nervous systems Study of the brain and how it works Structures and functions of the bottom part of the brain Structures that control emotion, lear ...
Chapter 16: Basal Ganglia
... further integrates the already highly integrated signals from the visual areas of the cortex, such as MT and V5. The parietal lobes are themselves closely interconnected with the prefrontal areas, and together these two regions represent the highest level of integration in the motor control hierarch ...
... further integrates the already highly integrated signals from the visual areas of the cortex, such as MT and V5. The parietal lobes are themselves closely interconnected with the prefrontal areas, and together these two regions represent the highest level of integration in the motor control hierarch ...
The Science of Psychology
... • Agonists - mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. • Antagonists - block or reduce a cell’s response to the action of other chemicals or neurotransmitters. Menu ...
... • Agonists - mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. • Antagonists - block or reduce a cell’s response to the action of other chemicals or neurotransmitters. Menu ...
Powerpoint version
... Found along the plasma membrane of all cells. Establishes gradients, controls osmotic effects, allows for cotransport ...
... Found along the plasma membrane of all cells. Establishes gradients, controls osmotic effects, allows for cotransport ...
Ch. 2 ppt
... • Agonists - mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. • Antagonists - block or reduce a cell’s response to the action of other chemicals or neurotransmitters. Menu ...
... • Agonists - mimic or enhance the effects of a neurotransmitter on the receptor sites of the next cell, increasing or decreasing the activity of that cell. • Antagonists - block or reduce a cell’s response to the action of other chemicals or neurotransmitters. Menu ...
Introduction: The Human Brain
... mood disorders, and the loss of acetylcholine in the cerebral cortex is characteristic of Alzheimer's disease. ...
... mood disorders, and the loss of acetylcholine in the cerebral cortex is characteristic of Alzheimer's disease. ...
Discontinuity in evolution: how different levels of organization imply
... We developed artificial organisms (O) that perform a simple navigation task in a simulated environment (Treves, Miglino, and Parisi, 1992). To each O corresponds a string of genetic material or genotype which specifies a set of developmental instructions. These instructions generate a certain number ...
... We developed artificial organisms (O) that perform a simple navigation task in a simulated environment (Treves, Miglino, and Parisi, 1992). To each O corresponds a string of genetic material or genotype which specifies a set of developmental instructions. These instructions generate a certain number ...
The Superior Olivary Nucleus and Its Influence on Nucleus
... pipette after contact with the cell surface. The formation of GV seals and the subsequent rupturing of the underlying membrane were monitored in voltage-clamp mode by measuring the resistive current resulting from a high-frequency, 25 mV pulse command. Stable recordings could be maintained up to 2 h ...
... pipette after contact with the cell surface. The formation of GV seals and the subsequent rupturing of the underlying membrane were monitored in voltage-clamp mode by measuring the resistive current resulting from a high-frequency, 25 mV pulse command. Stable recordings could be maintained up to 2 h ...
how different levels of organization imply pre
... We developed artificial organisms (O) that perform a simple navigation task in a simulated environment (Treves, Miglino, and Parisi, 1992). To each O corresponds a string of genetic material or genotype which specifies a set of developmental instructions. These instructions generate a certain number ...
... We developed artificial organisms (O) that perform a simple navigation task in a simulated environment (Treves, Miglino, and Parisi, 1992). To each O corresponds a string of genetic material or genotype which specifies a set of developmental instructions. These instructions generate a certain number ...
THE NERVOUS SYSTEM I
... neurons almost always occurs by chemical rather than electrical means. • Action potential causes release of specific chemical that are stored in synaptic vesicles in the presynaptic ending. • These chemicals are known as neurotransmitters and diffuse across the narrow gap between pre- and postsynapt ...
... neurons almost always occurs by chemical rather than electrical means. • Action potential causes release of specific chemical that are stored in synaptic vesicles in the presynaptic ending. • These chemicals are known as neurotransmitters and diffuse across the narrow gap between pre- and postsynapt ...
THE NERVOUS SYSTEM I
... neurons almost always occurs by chemical rather than electrical means. • Action potential causes release of specific chemical that are stored in synaptic vesicles in the presynaptic ending. • These chemicals are known as neurotransmitters and diffuse across the narrow gap between pre- and postsynapt ...
... neurons almost always occurs by chemical rather than electrical means. • Action potential causes release of specific chemical that are stored in synaptic vesicles in the presynaptic ending. • These chemicals are known as neurotransmitters and diffuse across the narrow gap between pre- and postsynapt ...
Chapter 12
... 32. Define the anatomic, chemical, enzymatic, and receptor components of a chemical synapse. 33. Go through the sequence of events that allow an action potential on an axon to be transmitted into a graded potential on a postsynaptic membrane. Excitatory and Inhibitory Postsynaptic Potentials 34. Ind ...
... 32. Define the anatomic, chemical, enzymatic, and receptor components of a chemical synapse. 33. Go through the sequence of events that allow an action potential on an axon to be transmitted into a graded potential on a postsynaptic membrane. Excitatory and Inhibitory Postsynaptic Potentials 34. Ind ...
Sequencing the connectome. - Cold Spring Harbor Laboratory
... Like any method, the sequencing approach is subject to false positives (i.e. inferred connections that do not exist) and false negatives (actual connections that are missed). Although the prevalence of each type of error will depend on the details of the implementation, with the sequencing approach ...
... Like any method, the sequencing approach is subject to false positives (i.e. inferred connections that do not exist) and false negatives (actual connections that are missed). Although the prevalence of each type of error will depend on the details of the implementation, with the sequencing approach ...
IOSR Journal of Electronics and Communication Engineering (IOSR-JECE)
... variables that vary in a regular and predictable way. During the time-varying process underlying a motor act, this state model is combined with instantaneous neural activity to update the predicted movement. Development of more sophisticated state space models will likely enhance cortical prosthetic ...
... variables that vary in a regular and predictable way. During the time-varying process underlying a motor act, this state model is combined with instantaneous neural activity to update the predicted movement. Development of more sophisticated state space models will likely enhance cortical prosthetic ...
Another Efferent (outgoing) System Autonomic Nervous System (ANS)
... activity. • Some autonomic reflexes are spinal reflexes & can function independent of the brain. • Spinal injuries can damage: – descending voluntary control pathways (ANS “UMNs”) – damage the “LMNs” of the ANS, causing loss of reflex responses ...
... activity. • Some autonomic reflexes are spinal reflexes & can function independent of the brain. • Spinal injuries can damage: – descending voluntary control pathways (ANS “UMNs”) – damage the “LMNs” of the ANS, causing loss of reflex responses ...
Time-delay-induced phase-transition to synchrony in coupled
... to have significant effects in the ensemble activity of neurons. Thus, in modeling studies of neurons and networks, the influence of time delays on the ensemble activity has received a great deal of attention recently.4–16 In networks of coupled neurons, time delays have been shown to affect not onl ...
... to have significant effects in the ensemble activity of neurons. Thus, in modeling studies of neurons and networks, the influence of time delays on the ensemble activity has received a great deal of attention recently.4–16 In networks of coupled neurons, time delays have been shown to affect not onl ...
Cholinergic induction of network oscillations at 40 Hz in the
... tonic and/or phasic excitatory activity seems to be important for these oscillations. Recurrent excitatory feedback in the CA3 region could be involved in the generation of the oscillations, and propagation to CA1 may depend on the excitatory Schaffer collateral input onto CA1 neurons. During 40-Hz ...
... tonic and/or phasic excitatory activity seems to be important for these oscillations. Recurrent excitatory feedback in the CA3 region could be involved in the generation of the oscillations, and propagation to CA1 may depend on the excitatory Schaffer collateral input onto CA1 neurons. During 40-Hz ...
Comparing neuronal and behavioral thresholds
... to the ones used in the human experiments. The dots’ average speed was optimized to match the preferred speed of the neurons. The pattern eccentricity varied from 5 to 121 from the fixation point, and the pattern size was approximately equal to that eccentricity. Most neurons had preferred speeds be ...
... to the ones used in the human experiments. The dots’ average speed was optimized to match the preferred speed of the neurons. The pattern eccentricity varied from 5 to 121 from the fixation point, and the pattern size was approximately equal to that eccentricity. Most neurons had preferred speeds be ...
Neurons – A whistle-stop Tour
... Between the axon terminal of one neuron and the dendrite is a tiny saltwater-filled gap called the synaptic cleft. The brain can transmit between 400 to 1,200 spikes per second, but cannot go at the top rate for more than a few seconds. A typical ‘spike’ requires 70 millivolts , or one-twentieth of ...
... Between the axon terminal of one neuron and the dendrite is a tiny saltwater-filled gap called the synaptic cleft. The brain can transmit between 400 to 1,200 spikes per second, but cannot go at the top rate for more than a few seconds. A typical ‘spike’ requires 70 millivolts , or one-twentieth of ...
Intro to the Biological Perspective
... brain. Because of this fact, the process of synaptic transmission in a particular portion of the brain can be altered through the use of drugs. Drugs that chemically affect the function of one of these neurotransmitters can influence behaviour and experience in specific ways. Thus our emerging knowl ...
... brain. Because of this fact, the process of synaptic transmission in a particular portion of the brain can be altered through the use of drugs. Drugs that chemically affect the function of one of these neurotransmitters can influence behaviour and experience in specific ways. Thus our emerging knowl ...
Intro to the Biological Perspective
... brain. Because of this fact, the process of synaptic transmission in a particular portion of the brain can be altered through the use of drugs. Drugs that chemically affect the function of one of these neurotransmitters can influence behaviour and experience in specific ways. Thus our emerging knowl ...
... brain. Because of this fact, the process of synaptic transmission in a particular portion of the brain can be altered through the use of drugs. Drugs that chemically affect the function of one of these neurotransmitters can influence behaviour and experience in specific ways. Thus our emerging knowl ...
Hydrogen peroxide-induced cell death in cultured Aplysia sensory
... can lead to impaired development and degenerative diseases, whereas too little can lead to cancer [38]. Therefore, it is very important that we understand the mechanisms of cell death from the pathological aspect. The two different patterns of cell death, apoptosis and necrosis, can be distinguished ...
... can lead to impaired development and degenerative diseases, whereas too little can lead to cancer [38]. Therefore, it is very important that we understand the mechanisms of cell death from the pathological aspect. The two different patterns of cell death, apoptosis and necrosis, can be distinguished ...
Optogenetics

Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.