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Hypophysis
Hypophysis

... contractions within the wall of the uterus as well as the oviduct. This action may facilitate sperm transport within the female reproductive tract. Oxytocin levels rise and increases uterine smooth muscle contractions during labor. Oxytocin also is believed to play a major role in certain behaviors ...
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No Slide Title

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Minireview - Leslie Vosshall
Minireview - Leslie Vosshall

... pheromone circuits, these neurons are tuned to pheromones. Does the subtle sexual dimorphism in DA1 glomerulus size translate to any male-female differences in neural activation? To answer this question, various groups have begun to trace the connectivity of pheromone circuits to higher brain center ...
Are We Paying Attention Yet?
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... visual field to detect brief visual stimuli with speeded keypress response Shifting-attention task involves endogenous cueing and stimuli at attended locations were detected faster than at unattended locations Central-detection task: subjects attended to and manually responded to stimuli in fovea wh ...
Chapter 14 The Autonomic Nervous System Chapter - CM
Chapter 14 The Autonomic Nervous System Chapter - CM

... 2. Effects on smooth muscle cells: when norepinephrine binds to specific receptors it mediates the following changes (Figure 14.7): a. Constriction of blood vessels serving the digestive, urinary, and integumentary system occurs when norepinephrine binds to receptors, which decreases blood flow to t ...
The Complicated Equation of Smell, Flavor, and Taste
The Complicated Equation of Smell, Flavor, and Taste

... the nose and its cavities.1 Although one cannot form without the other, neural crest cells get to their destination first. The olfactory receptor neurons are in the nasal cavity, and their axons, arranged in fascicles, traverse the cribriform plates and dura to synapse with cells in the olfactory bu ...
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2_Neuro-Bio_Review

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Basic Structure and Function of Neurons
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as a PDF

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cns structure - Department of Physiology
cns structure - Department of Physiology

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system quanta as discrete units of behavior
system quanta as discrete units of behavior

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Neurotransmitter Profile of Saccadic Omnipause Neurons in

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The Nervous System
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The avian `prefrontal cortex` and cognition - Ruhr-Universität
The avian `prefrontal cortex` and cognition - Ruhr-Universität

... The most obvious difference between the forebrains of mammals and birds is the lack of a laminated cortex within the avian telencephalon. The mammalian cortex, including neo-, archi- and paleocortical components, together with the claustrum and lateral parts of the amygdala, constitutes the forebrai ...
Introduction to Brain Structure - Center for Behavioral Neuroscience
Introduction to Brain Structure - Center for Behavioral Neuroscience

... that the species with the lower body weight would be more intelligent. One way to increase brain weight while maintaining the same brain size is to pack the neurons in more densely. One of the ways this is accomplished is by the convolutions (folding) of the cerebral cortex. Thus more advanced anima ...
Low-Power Circuits for Brain-Machine Interfaces
Low-Power Circuits for Brain-Machine Interfaces

... have emerged as an important experimental paradigm for investigating brain function. Experiments using such Brain-Machine Interfaces (BMIs) have shown that it is possible to predict intended limb movements by analyzing simultaneous recordings from many neurons. These findings have suggested a potent ...
12 - FacultyWeb
12 - FacultyWeb

... • Neural crest cells that come to lie alongside the cord form the dorsal root ganglia sensory neurons; axons grow into the dorsal aspect of the cord Copyright © 2010 Pearson Education, Inc. ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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