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Neural Correlates Underlying Action-intention and Aim-intention  Mauro Adenzato () Cristina Becchio
Neural Correlates Underlying Action-intention and Aim-intention Mauro Adenzato () Cristina Becchio

... expression here being "I intend to do X", while intending in the we-mode means intending as a group member, the relevant intention-expression here being "we together intend to do X" (where X can be done together or separately by us). ...
Brain Waves Volunteer Instructor Guide
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... When light enters the eye through the lens, it is captured on the retina at the back of the eye. The retina has cells, rods and cones, that sense light. Rods are for night vision and seeing movement. Cones detect colour and detail. This information goes through optic nerves and travels to the brain. ...
Theory of Arachnid Prey Localization
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... The sand scorpion is a nocturnal animal whose eyes are rudimentary. It lives in the deserts of Southern California and feeds mainly on small insects and other scorpions. During the daytime it stays in a burrow about 30 cm below the surface to escape surface temperatures of over 60 ±C. After sunset i ...
Sensory and Motor Mechanisms
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...  Many sensory neurons spontaneously generate action potentials at a low rate.  Therefore, a stimulus does not switch the production of action potentials on or off in these neurons.  Rather, it modulates action potential frequency.  The processing, or integration, of sensory information begins as ...
Morphology of Feedback Neurons in the Mushroom Body of the
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... Wild-Polyvar microscope (Leica, Bensheim, Germany). For this study, 28 specimens were evaluated. Each consisted of 1–20 marked neurons; thus, more than 200 neurons were stained and analyzed. According to their branching patterns, the feedback neurons could be classified into different classes. Howev ...
lmmunohistochemical Localization of Neuronal Nicotinic Receptors
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... areas are located in the posterolateral cortical waJl beneath the squamous portion of the temporal bone. The primary auditory area, 41 in Krieg's (1946a) classification, is the most dorsal and anterior part; Zilles et al. (1980) calls it TE 1. Two secondary auditory areas (TE3, TE2) form an incomple ...
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...  Appears to have a high iron content and is more vascular than the surrounding tissue - in some brains is pinkish  Inputs arise from motor areas of the brain and in particular the deep cerebellar nuclei (via superior cerebellar peduncle; crossed projection) and the motor cortex  Outputs: rubrospi ...
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... pathways have been characterized on the basis of anatomical,41 psychophysical,42,43 and physiological properties.28,44 Neurons in these 2 systems differ in terms of receptive field size, sensitivity to color and light contrast, and timing properties. The parvo system is ideally suited for form, text ...
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Cortical cfos Expression Reveals Broad Receptive Field Excitatory
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... thalamic and recurrent cortical inputs into the layer 2 network. To isolate this response for comparison between cells, we focused analysis on the earliest synaptic response: the first 30 ms following whisker deflection. Responses were averaged over multiple trials (8 to 57 trials per cell), and the ...
Using calcium imaging to understand function and learning in L2/3
Using calcium imaging to understand function and learning in L2/3

... organization  and  functional  basis  of  this  sparse  code  is  not  well  understood.  I  conducted  two   studies  to  characterize  function  and  learning  in  the  cortex.  In  the  first  study,  I  used  population   calcium  i ...
spinal cord
spinal cord

... The white matter contains axons that transfer information up and down the spinal cord. Ascending tracts that take sensory information to the brain occupy the dorsal and external lateral portions of the cord, ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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