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Hypothalamus and Limbic System, Lecture 2 Emotion and reward
Hypothalamus and Limbic System, Lecture 2 Emotion and reward

... VTA neurons provide a learning signal • The results from Schultz’s experiments show that VTA neurons provide a learning signal that reflects reward expectation. From a computational viewpoint, the cells’ firing rate is modulated when the reward received differs from the reward predicted. • This lear ...
Hypothalamus and Limbic System, Lecture 2
Hypothalamus and Limbic System, Lecture 2

... VTA neurons provide a learning signal • The results from Schultz’s experiments show that VTA neurons provide a learning signal that reflects reward expectation. From a computational viewpoint, the cells’ firing rate is modulated when the reward received differs from the reward predicted. • This lea ...
Histological Rearrangement in the Facial Nerve and Central Nuclei
Histological Rearrangement in the Facial Nerve and Central Nuclei

... z Schwann cell tubule has an important role both in supporting rapid growth and in the remyelination . z If they are not reinnervated after a certain period of time, they are atrophy and are replaced by fibrous tissue. ...
Responses to Odors Mapped in Snail Tentacle and Brain by [14C]
Responses to Odors Mapped in Snail Tentacle and Brain by [14C]

... encouraged a parallel approach in the snail. The experiments reported here had as their primary objective the identification of neural tissues responsive to environmental odors. The search for such tissues was limited to the specialized epidermal and neural apparatus at the tip of the posterior (opt ...
NeuN, a neuronal specific nuclear protein in vertebrates
NeuN, a neuronal specific nuclear protein in vertebrates

... matter of the spinal cord (Fig. 1C) and brain (Fig. 1B), and Bergmann glia in the cerebellum (Fig. 2A, B).Fig. 3 shows a region of the hippocampus double-labelled with mAb A60 and a rabbit anti-GFAP antibody (see Fig. 3 legend), both visualized with HRP/DAB. The nuclei of the hippocampal neurons sho ...
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Stem Cells may Beat Riluzole in Treatment of Amyotrophic Lateral
Stem Cells may Beat Riluzole in Treatment of Amyotrophic Lateral

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Nose, Nerve – Atrophy
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NNIntro
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lec3 - Department of Computer Science
lec3 - Department of Computer Science

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Supplementary Information (doc 2382K)
Supplementary Information (doc 2382K)

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Sensory Regeneration in Arthropods: Implications of Homoeosis
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PNS Extra credit worksheet. Use the text and your power point notes
PNS Extra credit worksheet. Use the text and your power point notes

... Receptors located in the body that detect changes in the environment may be classified as ____________________________, while those that send information about internal organs are called _____________________________. Receptors that relay information about muscles and joint position are called ____ ...
Release of chemical transmitters from cell bodies and dendrites of
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... towards the active zone. Membrane proteins of a vesicle that will interact with the active zone material must arrive in a characteristic arrangement determined by a radial assembly of macromolecules. As a result, in response to electrical stimulation, a specific region of the vesicle membrane—the fu ...
A proposed common neural mechanism for categorization and
A proposed common neural mechanism for categorization and

... From an ­evolutionary perspective, the intentional ­framework could have developed by the decision circuitry incorporating into established sensorimotor networks19. The intentional ­framework may also extend to other types of decisions; for example, Glimcher and colleagues have proposed a similar ac ...
Neural characterization in partially observed populations of spiking
Neural characterization in partially observed populations of spiking

... less well capturing the response properties of neurons in deeper brain areas, owing in part to the fact that they do not take into account multiple stages of processing. Here we introduce a new twist on the point-process modeling approach: we include unobserved as well as observed spiking neurons in ...
Odorant Category Profile Selectivity of Olfactory Cortex Neurons
Odorant Category Profile Selectivity of Olfactory Cortex Neurons

... The olfactory cortex receives converging axonal inputs from many mitral and tufted cells in the olfactory bulb. Recent studies indicate that single cortical neurons integrate signals from diverse odorants. However, there remains a basic question, namely, the signals from which kinds of odorants are ...
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence

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Cerebellum: The Brain for an Implicit Self
Cerebellum: The Brain for an Implicit Self

... Neuroscience is now dominated by the effort to decompose neuronal circuits into their cellular and molecular components. Many would argue, however, that reconstructing models of such circuits is equally important in our attempt to comprehend their functional principles (e.g., van Hemmen and Sejnowsk ...
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PDF file

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Brain Computer Interface Seminar Report
Brain Computer Interface Seminar Report

... development in recent years. Most of the effort has been dedicated to the design of user-friendly or ergonomic systems by means of innovative interfaces such as voice recognition, virtual reality. A direct brain-computer interface would add a new dimension to man-machine interaction. A brain-compute ...
Sensory, Motor, and Integrative Systems
Sensory, Motor, and Integrative Systems

...  Located in the stratum basale of the dermis.  Attached to medium-diameter type A myelinated fibers.  Temperatures between 10⁰ and 40⁰C activate them.  Warm receptors:  Located in the dermis.  Not as abundant as cold receptors.  Attached to small-diamtere unmyelinated C fibers.  Temperatures ...
Homework
Homework

... and endocrine systems regulate conditions in the body. 3. Neurons transmit electrochemical impulses. 4. Sensory neurons, interneurons, and motor neurons all have a role in sensation, thought and response. Essential Questions: 1. How does the structure of the nervous system allow it to function? 2. H ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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