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Stem cell-based cellular replacement strategies following traumatic
Stem cell-based cellular replacement strategies following traumatic

... cavity at one week following controlled cortical impact brain injury in immunocompetent mice (39). At all time points examined (one week to three months post-transplant), GFP-positive cells were confined to the ipsilateral host brain tissue. At one week, cells injected into the injury cavity lined t ...
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neuron number decreases in the rat ventral, but not dorsal, medial
neuron number decreases in the rat ventral, but not dorsal, medial

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... http://www.neurobio.ucla.edu/~dbuono/InterThr.htm ...
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Open access
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Structural Repair and Functional Recovery Following Cerebral

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1 Revised 10/11/2016 The Physiology of the Senses Lecture 7
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Top-down influence in early visual processing: a Bayesian perspective

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Specialized Neurons, Their Characteristics And

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Differential Temporal Storage Capacity in the Baseline Activity of

... FEF neurons than those in V4 neurons. The finding that there are region-specific differences in a neuron’s ability to store the history of its own activity in the absence of sensory or cognitive information processing suggests that there are differences in the intrinsic properties of the neural circ ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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