• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Purine Oct 20 - LSU School of Medicine
Purine Oct 20 - LSU School of Medicine

... group on the polarized phosphate to yield a 2’-3’ cyclic phosphodiester intermediate (circled) that subsequently spontaneously hydrolyzes to a mix of 2’- and 3’phosphomonoesters. ...
- Deans Community High School
- Deans Community High School

... (c) Why is molecule A polar while molecule B is non-polar? 18. Chlorofluorocarbons, commonly known as CFC’s are widely used in fridges, aerosols, and to preserve blood in blood banks. Information about three CFC’s is shown in the table. ...
Lecture #13 – Introduction to Amino Acids and Proteins
Lecture #13 – Introduction to Amino Acids and Proteins

... place to place. ...
- TestbankU
- TestbankU

... chemistry is fundamental to a functional understanding of the many structures that bacteria possess. It is important for students to understand that that everything is made up of chemicals and that life relies on chemical reactions. After all, cells are really just big bags of chemicals and the proc ...
2287 Summary
2287 Summary

... hour for bromopropiophenone, seventeen to eighteen hours for a-bromobutyrophenone, twenty-four hours for a-bromovalerophenone). The reaction flask was immersed in ice water during the reaction and stirring was continued for one-half to three-quarters of an hour after the addition of the bromo compou ...
Improved recovery of enzyme activity after
Improved recovery of enzyme activity after

... Energy Commission under contract with Union Carbide Corporation and by the AEC Postdoctoral Fellowship Program of the Oak Ridge Associated Universities). - - - Biology Division, Oak Ridge Ntitional Laboratory, Qak Ridge, Tennessee ...
Amino Acids
Amino Acids

... The concept of electrophoresis, a common tool used for separation of amino acids and analysis of proteins, utilizes separation based on a particular pH and the isoelectric points of amino acids. By varying the pH of a system, the charges on the amino acids will vary from positive to neutral to negat ...
Benzocaine Synthesis via Esterification
Benzocaine Synthesis via Esterification

... (along with the stir bar) into a 200 mL beaker containing 30 mL of ice water. While stirring this mixture, slowly add approximately 10 mL of a 10% Na2CO3 solution. Gas evolution will be observed as the acid is neutralized; the final pH should be approximately 8. Vacuum filter the resulting precipita ...
Unit 3 Review Questions
Unit 3 Review Questions

... 34. DNA and polypeptide sequences from closely related species are more similar to each other than sequences from more distantly related species. For the remaining questions, you will look at amino acid sequence data for the β polypeptide chain of hemoglobin, often called β-globin. You will then in ...
Ultramer® Oligonucleotides - Integrated DNA Technologies
Ultramer® Oligonucleotides - Integrated DNA Technologies

... of Ultramer Oligonucleotides for de novo gene construction. Many of the published procedures for constructing specific DNA sequences from oligos use relatively short sequences (≤60mer) with overlapping stretches of common sequence that permit annealing, followed by assembly using PCR-based strategie ...
Protein Sequence Analysis in SeqWEB
Protein Sequence Analysis in SeqWEB

Synthesis of Esters Problem: Produce an ester that smells
Synthesis of Esters Problem: Produce an ester that smells

... hundreds of compounds are made and tested at the same time. In this experiment we are interested in making an ester that smells like bananas. Knowing that esters are made from a carboxylic acid and an alcohol, you could systematically react all the carboxylic acids and alcohols available in our stor ...
Powerpoint file - revised
Powerpoint file - revised

... •The ribosome translating the trp leader mRNA follows closely behind the RNA polymerase that is transcribing the DNA template. •Alternative conformation adopted by the leader mRNA. ...
From Gene to Protein
From Gene to Protein

Biochemistry
Biochemistry

... millions of copies of each section are made. The sections (STR or short tandem repeats) are then separated by electrophoresis and compared with those from a known source which should have similar STRs in the same proportions. This technique is used to identify criminals and to trace ancestry. Figure ...
Moringa Info. - Sita`s Super Foods
Moringa Info. - Sita`s Super Foods

... vitamins and amino acids, the dried leaves can provide a large percentage of the daily requirements for calcium, iron, magnesium, potassium and zinc. As a result, the leaves are often used to supplement the diets of expecting and nursing mothers and young children. Lack of iron can lead to anemia an ...
Name: Chem 22 Final exam Spring `00 What product is formed when
Name: Chem 22 Final exam Spring `00 What product is formed when

... a) In an organometallic compound, the carbon bonded to the metal is the nucleophile. b) An epoxide is more reactive than an ether. c) In a Hofmann elimination, a proton is removed from the beta carbon that is bonded to the greater number of hydrogens. d) Thioethers are also called sufides ...
Nucleoside Phosphoramidate Monoesters: Potential
Nucleoside Phosphoramidate Monoesters: Potential

... initiation, elongation, and termination steps. 4) Eukaryotic mRNA is extensively processed ...
COMMON SYNTHETIC SEQUENCES FOR OCHEM I
COMMON SYNTHETIC SEQUENCES FOR OCHEM I

... it serves no purpose other than to meet an academic requirement. It is true that a lot of organic reactions seem to lack meaning in and of themselves, but obviously they are not useless. Unfortunately students do not get exposed to the contexts in which this information comes to life until later, or ...
Features: An oxidants - contains various sources from both natural
Features: An oxidants - contains various sources from both natural

Document
Document

... The Functional and Evolutionary Importance of Introns, p. 336 One consequence of the presence of introns is that a ____________ gene can encode more than one kind of ________________________. Alternative RNA splicing – different segments of RNA are treated as ____________ Presence of introns in a ge ...
DNA and Protein Synthesis – Grade 10
DNA and Protein Synthesis – Grade 10

... DNA on the banner, resulting in the changing of one base in the sequence. The G in the ATG triplet was altered to a T (the triplet now is ATT). Cover the G on the card with a T to indicate the change. 11. Ask the class to determine what effect the change might have on the protein that is made. Direc ...
Nitrogen Compounds
Nitrogen Compounds

... slowly (with cooling and stirring) to a cold solution of the amine compound in excess hydrochloric acid The temperature must not rise above 5°C. This solution (still cold) should then be added slowly with stirring to a solution of the coupling compound. This should be kept below 5°C the whole time. ...
Basic Biochemistry
Basic Biochemistry

...  Usually found away from the water  Inside proteins in the CORE  Methionine contains Sulphur  Figure 2-9, page 29 (2-7, page 29)  Proline => Unique with a cyclic side chain  Often found at bends in protein structures  Figure 2-10, page 30 (2-7, page 29 and 2-8, page 30)  Aromatic amino acids ...
Chapter 13. Plannig and Execution of Multistep Synthesis
Chapter 13. Plannig and Execution of Multistep Synthesis

... and esters are not as convenient as those for alcohols, aldehydes and ketones. So, the carboxylic acid can then be formed at a late stage in the synthesis by an appropriate oxidation. ...
< 1 ... 71 72 73 74 75 76 77 78 79 ... 152 >

Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report