• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Chapter 13. Plannig and Execution of Multistep Synthesis
Chapter 13. Plannig and Execution of Multistep Synthesis

... and esters are not as convenient as those for alcohols, aldehydes and ketones. So, the carboxylic acid can then be formed at a late stage in the synthesis by an appropriate oxidation. ...
Transcription and Translation
Transcription and Translation

... • No tRNA normally exists that can form base pairing with a STOP codon; recognized by a release factor • tRNA charged with last amino acid will remain at P site • Release factors cleave the amino acid from the tRNA • Ribosome subunits dissociate from each other • Review the animation of translation ...
de48db8e6ca67d8
de48db8e6ca67d8

... have unpleasant odors and flavors. Fats and oils containing them are said to have become rancid. • Rancidity is due to a combination of two reactions: Bacterial hydrolysis of ester bonds. Air oxidation of alkene double bonds. ...
I N IN  VIVO VITRO
I N IN VIVO VITRO

... and BTV-RNA. These results taken together clearly indicate that a virus-specific single-stranded RNA, capable of hybridizing with the viral genome, is synthesized in BTV-infected BHK cells at a linear rate for at least 7 hours after infection, under conditions where synthesis of cellular RNA and pro ...
Exam 1
Exam 1

... t-butyl methanoate ...
Mutation Activity
Mutation Activity

... individual. Every three bases are known as a codon and codes for an amino acid. Proteins are made up of amino acids and the order of them determines the protein made. In this way the order of the bases in the DNA molecule determines which proteins are made. DNA is found in the nucleus of the cell, b ...
Biological Polymers - McQuarrie General Chemistry
Biological Polymers - McQuarrie General Chemistry

... l-isomers of the amino acids occur in biological systems. Biochemical reactions are exceptionally stereo­ specific; that is, they are extremely dependent on the shape of the reactants. Apparently, most of the life on earth originated from l-amino acids; and once the process started, it continued to ...
Introductory Signposting - Oklahoma State University
Introductory Signposting - Oklahoma State University

... – extra neutrons versus the periodic table – not radioisotopes ...
Key
Key

Arylacylamidase Product Sheet
Arylacylamidase Product Sheet

... in the presence of periodate to form an indophenol, which absorbs strongly at 615 nm. Used for the enzymatic determination of acetaminophen in serum Measures the increase of p-aminophenol via secondary ...
Chapter 18: Aldehydes and Ketones II Worksheet
Chapter 18: Aldehydes and Ketones II Worksheet

... ...
Mutations Worksheet
Mutations Worksheet

... The statement “DNA goes to RNA goes to protein” is used as a shorthand description of the flow of information in the cell. a) “DNA goes to RNA” is meant to describe the process of _______________________. For this process to occur, we need an enzyme called _____________________ that uses DNA as a te ...
Replication The Cell Cycle Cell Cycle Cartoon Replication Occurs
Replication The Cell Cycle Cell Cycle Cartoon Replication Occurs

... • Since 3’-5’ exo leaves 3’OH product on primer, 5’dNTP may be added to proofread • Therefore, the requirement for a 5’→3’ direction is necessary for proofreading. ...
Gene expression powerpoint
Gene expression powerpoint

... one person starts: “First….,” and says one sentence. The next group member picks up where the first left off, and so on. ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 12. What is meant by lactose intolerance? How it can be overcome? 13. How the viscosity of starch solution is related to its structure? 14. Give a brief account of cyclodextrins and their use. 15. Explain the biological role of NAD+. 16. What are (i) oxidoreductases (ii) transferases. Give two examp ...
Chapter 21 Worksheet
Chapter 21 Worksheet

... c. If there are no functional groups, give the substituents the lowest possible numbers. If you get the same numbers from either end assign the alphabetically first substituent the lowest number. 3. Naming your compound. a. If the compound has a specific configuration or geometry (cis/trans, E/Z or ...
Mutation Activity - Northwest ISD Moodle
Mutation Activity - Northwest ISD Moodle

... individual. Every three bases are known as a codon and codes for an amino acid. Proteins are made up of amino acids and the order of them determines the protein made. In this way the order of the bases in the DNA molecule determines which proteins are made. DNA is found in the nucleus of the cell, b ...
HS-LS1-1 Taco Protein Synthesis Activity.docx
HS-LS1-1 Taco Protein Synthesis Activity.docx

... 5. Now that you have completed your table, draw a picture of your taco that was created on a separate sheet of paper (use color). Attach this piece of paper to this lab. Make sure you label each part of your taco. For example, if you draw a hard shell it would be labeled AUG (see key). 6. Build your ...
3 | Amino Acids, Peptides, Proteins
3 | Amino Acids, Peptides, Proteins

... • Proteins are linear heteropolymers of ‐amino acids • Amino acids have properties that are well‐suited to carry  out a variety of biological functions ...
Primer Design Considerations for Adding a T7 Promoter
Primer Design Considerations for Adding a T7 Promoter

... Eukaryotic translation initiation sequences from sequence being amplified. Increases efficiency of translation initiation. • 6–10 bases upstream of promoter. Improves efficiency of promoter. • 3- to 6-base spacer between promoter sequence and Kozak sequence. Ensures transcription starts ...
CHAPTER 12 - powerpoint
CHAPTER 12 - powerpoint

... remaining 60 codons code for 19 different amino acids. • This means that many amino acids have more than one codon. Thus the code is redundant. ...
Chapt21 Lecture 13ed Pt 2
Chapt21 Lecture 13ed Pt 2

... ________ while RNA is ______________. – DNA has T while RNA has U. – RNA is also found in the ___________ as well as the nucleus while DNA is not. ...
From http://www
From http://www

... When the RNA copy is complete, it snakes out into the outer part of the cell. Then in a dazzling display of choreography, all the components of a molecular machine lock together around the RNA to form a miniature factory called a ribosome. It translates the genetic information in the RNA into a stri ...
Lecture #
Lecture #

... This is a list of topics we will be covering to help you in preparation for exams. Topics from Clayden are indicated clearly by chapter and page numbers where necessary. Topics NOT from Clayden are listed in italics. PLTL topics are in CAPS. This document will be updated throughout the term. The goa ...
HL  ISSN: 2231 – 3087(print) / 2230 – 9632 (Online)
HL ISSN: 2231 – 3087(print) / 2230 – 9632 (Online)

< 1 ... 72 73 74 75 76 77 78 79 80 ... 152 >

Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report