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Bio1A - Lec 2 slides File
Bio1A - Lec 2 slides File

... Androgen Receptor is a protein that has a helix shape which allows it to fit into DNA. The helix is an example of what level of protein structure? a)Primary b)Secondary c)Tertiary d)Quatenary ...
DNA transcription
DNA transcription

... when RNA polymerase crosses a stop (termination) sequence in the gene. The mRNA strand is complete, and it detaches from DNA. ...
Table of K Values a pK
Table of K Values a pK

Test 3 Test Skills/Competencies
Test 3 Test Skills/Competencies

... f. Amines (reversible aminol and imine formation, including cyclic aminols and imines, and the reverse reaction involving imine hydrolysis) Mechanisms: Be able to draw mechanisms for carbonyl reactions listed above, including the reverse reaction, including those involving rings. Major mechanisms in ...
Questions, chapter 14
Questions, chapter 14

... and RF2 (UAG by RF1, UGA by RF2, and UAA by both RF1 and RF2). These factors are composed entirely of protein, and use a particular stretch of three amino acids to form a "peptide anticodon" that binds to and specifically recognizes the stop codon. When the ribosome encounters a stop codon, RF1 or R ...
Genes and How They Work
Genes and How They Work

... RNA Polymerase binds to Promotor site Reads from start sequence(TAC) assembles complementary single strand of RNA (primary RNA) ...
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... fingerprint region is. ...
A NOVEL BIOCHEMICAL METHOD FOR PRODUCTION OF AN ANTIBACTERIAL DRUG
A NOVEL BIOCHEMICAL METHOD FOR PRODUCTION OF AN ANTIBACTERIAL DRUG

Macromolecules & Enzymes
Macromolecules & Enzymes

...  The changing of one set of chemicals into another set of chemicals  Reactants start the reaction.  Products are produced by the reactants. Ex: CO2 + H2O H2CO3 Reactants (before arrow) ...
Detecting Constituent Sequences by Means of HP Pattern–Based
Detecting Constituent Sequences by Means of HP Pattern–Based

... Many other proteins containing PH Domain, are not directly involved in the biology of phosphoinositides. Most of these proteins are, however, closely associated with membranes in cells. [1] Some PH molecules can bind inositol phosphates at a characteristic corner of the PH domain which is formed by ...
Universal Kinase and GTPase Assays
Universal Kinase and GTPase Assays

... Fixed-time kinase assays typically employ indirect detection mechanisms, such as monitoring binding of a phosphorylated product to an immobilized metal ion or antibody; such assays are not ideal because they use multiple reagents, employ indirect measurements, require the presence of the kinase’s su ...
RNA - Universitas Esa Unggul
RNA - Universitas Esa Unggul

... mRNA carries information about a protein sequence to the ribosomes, the protein synthesis factories in the cell. It is coded so that every three nucleotides (a codon) correspond to one amino acid. In eukaryotic cells, once precursor mRNA (pre-mRNA) has been transcribed from DNA, it is processed to m ...
Erythro and Threo
Erythro and Threo

... D-(-)-Threose ...
Ninety-nine Point Nine Percent of the Time, Nature Uses the... Acids, and We Don’t Know Exactly Why
Ninety-nine Point Nine Percent of the Time, Nature Uses the... Acids, and We Don’t Know Exactly Why

... A third feature of the codon language that contributes to a softening of the consequences of errors is a pattern of codon similarity between codons that represent functionally similar amino acids. It was proposed as early as the 1960’s that “nearly all transitions between functionally closely relat ...
apbio ch 17 study guide
apbio ch 17 study guide

... Exceptions to the universality of the genetic code exist in certain unicellular eukaryotes and in the organelle genes of some species. o Some prokaryotes can translate stop codons into one of two amino acids not found in most organisms. o One of these amino acids, pyrrolysine, is found only in archa ...
Dess-Martin Periodinane
Dess-Martin Periodinane

Esterification
Esterification

CYSTEINE
CYSTEINE

Investigating Esters
Investigating Esters

... not be possible to determine the boiling point by the distillation method and a semi micro method should be employed. The suggested method in the starter experiment is a generic one and may need to be slightly adjusted for each ester. Students should be encouraged to find details from the literature ...
Methicillin-Resistant Staphylococcus Aureus (MRSA)
Methicillin-Resistant Staphylococcus Aureus (MRSA)

... Staphylococcus aureus (staph) is commonly found on the You can stop the skin or in noses of healthy people and does not normally cause infection. MRSA is a type of staph that is resistant to spread of MRSA antibiotics–making it more difficult to treat. ■ MRSA is a common cause of minor skin infe ...
Investigating Esters
Investigating Esters

From DNA to Protein
From DNA to Protein

... – Initiator tRNA is different than the tRNA that adds other Met Ribosomal Assembly Initiation Phase • Initiation factors (IFs) catalyze the steps – not well defined • Step 1 – small ribosomal subunit with the IF finds the start codon –AUG – Moves 5’ to 3’ on mRNA – Initiator tRNA brings in the 1st A ...
Molecules of Life
Molecules of Life

Biomolecules Discussion
Biomolecules Discussion

Chapter 3 Study Guide
Chapter 3 Study Guide

... nucleic acids Know how excess glucose is stored Know dipeptide, tripeptide, polypeptide, disaccharide, polysaccharide Know the functional groups of amino acids Know peptide bonds Know what a glycerol and fatty acid are Know dehydration synthesis and hydrolysis Know condensation reaction Know monomer ...
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Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
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