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Higher Chemistry Unit 2 - Section 1 Fuels Multiple Choice Questions
Higher Chemistry Unit 2 - Section 1 Fuels Multiple Choice Questions

... This is designed to be used by teachers to help students develop skills in answering multiple choice questions. ...
Antiparasitic Drugs
Antiparasitic Drugs

... produces four alkaloids that were, until recently, the prototypical molecules on which most antimalarial drugs based. Quinine has been used for “fevers” in South America since 1600s. The pure alkaloids quinine and cinchonine were isolated in ...
Ch6-4_Enzymes-New
Ch6-4_Enzymes-New

... Located on the p arm of chromosome 1 in humans, this gene codes for an enzyme involved in the methylation of folic acid, a necessary B vitamin. Methylated (folate) and non-methylated (folic acid) forms are found in leafy greens, beans, and whole grains. ...
Dormancy Metabolism Characteristics
Dormancy Metabolism Characteristics

Protein Synthesis
Protein Synthesis

... http://www.dnalc.org/view/16360-Animation-16-One-gene-makes-one-protein-.html (no narrator) ...
notes pdf - Auburn University
notes pdf - Auburn University

... 8. How does transcription differ between prokaryotes and eukaryotes? 9. What is a codon? 10. What is the genetic code? 11. Why are the “words” in the genetic code three bases long? 12. Diagram a mature mRNA. 13. Describe the events of initiation, elongation, and termination of translation. Be sure t ...
protein expression (pdf, en, 2701 KB, 4/8/10)
protein expression (pdf, en, 2701 KB, 4/8/10)

... ResidueResidue-specific enrichment It is achieved using E. coli auxotrophic strains which are grown in the presence of selected labeled aminoacids or using more sophisticated techniques such as cellcell-free. The latter approach allows to simplify problems due to protein size. It is possible to focu ...
Alcohols, Aldehydes and Ketones
Alcohols, Aldehydes and Ketones

... This shows that Propan 1-ol, Propan 2-ol and Propanal are oxidized only, being a primary, secondary alcohol and aldehdye. 2 Methyl propan2-ol is a tertiary alcohol and Propanone a ketone which can not be oxidized. The Fehlings solution has changed colour which is a result of the formation of Cu 2+ b ...
Chapter 7: Alkenes and Alkynes – Properties and Synthesis
Chapter 7: Alkenes and Alkynes – Properties and Synthesis

... Alkene Diastereomers: Cis-Trans vs. E-Z ...
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PowerPoint-RNA
PowerPoint-RNA

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Targeted Chemical Libraries
Targeted Chemical Libraries

... and standard organic glassware, this would be a daunting endeavor for even the most  dedicated and hard‐working chemist.  This problem was recognized in the 1990s in conjunction  with the explosion of combinatorial chemistry, and several efforts began to make solution  phase chemistry competitive w ...
cAMP-Dependent Protein Kinase, Catalytic Subunit Product
cAMP-Dependent Protein Kinase, Catalytic Subunit Product

... in intracellular cAMP levels regulate cellular responses by influencing interaction between the Regulatory (R) and Catalytic (C) Subunits of PKA (6). The PKA holoenzyme exists as an inactive tetrameric complex (R2C2), which consists of a regulatory dimer (R2) associated with two Catalytic Subunits. ...
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bcaa power - ProAction
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... This mechanism enables BCAA catabolism to be activated, providing the diet is rich in these amino acids. BCKDH is also activated by low levels of ATP and pH, by glycogen depletion, and by physical exercise. It is worth noting that, in addition to promoting protein catabolism, sports training also ca ...
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GENE EXPRESSION: CONTROL IN BACTERIA AND PHAGES
GENE EXPRESSION: CONTROL IN BACTERIA AND PHAGES

... the bacterial genome and enter the lytic cycle in the recipient cell. b. At 42°C, the  CI repressor would denature and the prophage would excise from the bacterial genome. With the -DNA being absent from the bacterial genome, it could not be transferred by conjugation and the recipient cell could ...
PROTEIN SYNTHESIS: TRANSLATION AND
PROTEIN SYNTHESIS: TRANSLATION AND

... perhaps along with X-ray crystallography, should lead to a more detailed and complete model of the ribosome. ...
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IMPROVING ENANTIOSELECTIVITY OF ENZYMES THROUGH
IMPROVING ENANTIOSELECTIVITY OF ENZYMES THROUGH

... from 100 mM to 0.5, 1, 2, and 3 M, the enantiomeric excess decreased to 92.1, 90.7, 89.2, and 87.6% respectively. GSSM created 31,584 clones that were screened to identify the mutants with improved enantioselectivity at higher substrate concentrations. A novel high-throughput assay was developed usi ...
Lecture 9 (09/25/2007): Non-coding RNA genes
Lecture 9 (09/25/2007): Non-coding RNA genes

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Lesson 3
Lesson 3

... • For the design of media used for the production of cell mass, the determination of an elemental material balance is a useful exercise. • For defined media, the determination is a straightforward calculation from the components. • For complex media, Traders’ Co. and other manufacturers of complex n ...


... is advantageous over the chemical ones, as they ensure the stereo-selective obtaining of the product. Although it has been shown that their chemical synthesis was well-developed, the method still employs toxic and expensive compounds to yield α and β-configuration products via several steps. Hence, ...
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Bottromycin



Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.
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