... terminus. FMDV 2A activity was studied in artificial polyproteins in which sequences encoding reporter proteins flanked the 2A sequence such that a single, long, open reading frame was created. The self-processing properties of these artificial polyproteins were investigated and the co-translational ...
Synthesis, Characterisation of Novel NLO Material
... Received 27 November 2015 / Accepted 18 December 2015 ...
... Received 27 November 2015 / Accepted 18 December 2015 ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
... 18. How are oxidizing agents chemoselective? Explain with suitable examples. 19. Explain the mechanism of Aldol condensation and Wittig reaction. 20. Discuss the mechanism of Baeyer Villiger reaction with suitable example. 21. Discuss on the electroorganic synthesis by reduction with suitable exampl ...
... 18. How are oxidizing agents chemoselective? Explain with suitable examples. 19. Explain the mechanism of Aldol condensation and Wittig reaction. 20. Discuss the mechanism of Baeyer Villiger reaction with suitable example. 21. Discuss on the electroorganic synthesis by reduction with suitable exampl ...
Macromolecules
... Structure and Function mean? • Structure = the body plan, or the way the parts are arranged • Function = the job for that part of the organism ...
... Structure and Function mean? • Structure = the body plan, or the way the parts are arranged • Function = the job for that part of the organism ...
Introduction to Biodiesel Chemistry
... Organic chemistry is the branch of chemistry that deals with organic compounds. Organic compounds are compounds that (with a few exceptions such as carbon dioxide gas) contain the element carbon. The properties of organic compounds are dependent primarily on the physical structure of the molecules a ...
... Organic chemistry is the branch of chemistry that deals with organic compounds. Organic compounds are compounds that (with a few exceptions such as carbon dioxide gas) contain the element carbon. The properties of organic compounds are dependent primarily on the physical structure of the molecules a ...
Relationship between the structure and function of proteins
... It is a relatively small protein made up of a single polypeptide chain that contains 153 amino acid residues . It contains a heme group (which is a prosthetic group consisting of a protoporphyrin organic ring and a central iron atom). It is the heme group which is responsible for the oxygen binding ...
... It is a relatively small protein made up of a single polypeptide chain that contains 153 amino acid residues . It contains a heme group (which is a prosthetic group consisting of a protoporphyrin organic ring and a central iron atom). It is the heme group which is responsible for the oxygen binding ...
CBS Reduction
... Recent paper 2016 • Sanderson and coworkers developed flow process for CBS asymmetric reduction of ketones , using chip-microreactors. • They used BH3 , (85% 2-MeTHF, 15% THF) and oxazaborolidine for reduction. • Under such reaction conditions, the reaction was complete in 10 minutes and alcohol wa ...
... Recent paper 2016 • Sanderson and coworkers developed flow process for CBS asymmetric reduction of ketones , using chip-microreactors. • They used BH3 , (85% 2-MeTHF, 15% THF) and oxazaborolidine for reduction. • Under such reaction conditions, the reaction was complete in 10 minutes and alcohol wa ...
Topic 13 – Biomolecules
... include muscles, tendons, fingernails, enzymes antibodies and many hormones. Generally speaking proteins are classified as being Fibrous these are the structural proteins like muscle and tendons Globular these tend to be the working proteins and include enzymes and antibodies Conjugated these ...
... include muscles, tendons, fingernails, enzymes antibodies and many hormones. Generally speaking proteins are classified as being Fibrous these are the structural proteins like muscle and tendons Globular these tend to be the working proteins and include enzymes and antibodies Conjugated these ...
Carboxylic Acid Questions 1.-Arrange the following in order of (i
... (b) LiAlH4 is a hydride reducing agent, acids to primary alcohols. (c) An alcohol and a carboxylic acid give an ester. (d) Carboxylic acids react with bases to give carboxylates. ...
... (b) LiAlH4 is a hydride reducing agent, acids to primary alcohols. (c) An alcohol and a carboxylic acid give an ester. (d) Carboxylic acids react with bases to give carboxylates. ...
From Gene to Protein—Transcription and Translation
... nucleotides have the same shape, so you will have to use the nucleotide abbreviations and the basepairing rule to match the appropriate RNA nucleotide with each DNA nucleotide. 3. Cytoplasm: Give the next RNA nucleotide (complementary to the next DNA nucleotide) to the RNA polymerase person. RNA pol ...
... nucleotides have the same shape, so you will have to use the nucleotide abbreviations and the basepairing rule to match the appropriate RNA nucleotide with each DNA nucleotide. 3. Cytoplasm: Give the next RNA nucleotide (complementary to the next DNA nucleotide) to the RNA polymerase person. RNA pol ...
Molecular Weight and the Metal Amino Acid Chelate
... still need to be digested before absorption could occur because true amino acid chelates are absorbed via the dipeptide absorption pathway. 3 In the case of an amino acid chelate with a molecular weight of less than 800 daltons, there is no need for digestion prior to absorption which results in gre ...
... still need to be digested before absorption could occur because true amino acid chelates are absorbed via the dipeptide absorption pathway. 3 In the case of an amino acid chelate with a molecular weight of less than 800 daltons, there is no need for digestion prior to absorption which results in gre ...
RNA and DNA aptamers. Ribozymes and DNAzymes Daniel
... FMN (and an RNA aptamer is found naturally in E.coli) ...
... FMN (and an RNA aptamer is found naturally in E.coli) ...
Week 9
... Objective: Students will use their knowledge of carbohydrates and their power of observations to test three known solutions to determine how mono, di and polysaccharides react to specific indicator test. Activity: Five minute exercise reviewing Activity: Complete lecture on Activity: Pre-lab the Car ...
... Objective: Students will use their knowledge of carbohydrates and their power of observations to test three known solutions to determine how mono, di and polysaccharides react to specific indicator test. Activity: Five minute exercise reviewing Activity: Complete lecture on Activity: Pre-lab the Car ...
Unit 3 Exam Enzymes REVIEW
... Protein Structure (3.6): How is a protein polymerized? What makes 1 protein different than another? Compare primary and tertiary structure. Why do some amino acids’ R groups interact with each other but others don’t? Choose 3 amino acids to compare/contrast. What can cause R groups to no longer inte ...
... Protein Structure (3.6): How is a protein polymerized? What makes 1 protein different than another? Compare primary and tertiary structure. Why do some amino acids’ R groups interact with each other but others don’t? Choose 3 amino acids to compare/contrast. What can cause R groups to no longer inte ...
Rottlerin
... Inhibits protein kinase C δ (PKCδ, IC50 = 3-6 µM) and PKCθ isozymes. Also inhibits PKCα, PKCβ, and PKCγ isoforms, but with significantly reduced potency (IC50 = 30-42 µM). Has reduced inhibitory activity on PKCε, PKCη, and PKCξ (IC50 = 80-100 µM). Also known to inhibit CaM kinase III (IC50 = 5.3 µM) ...
... Inhibits protein kinase C δ (PKCδ, IC50 = 3-6 µM) and PKCθ isozymes. Also inhibits PKCα, PKCβ, and PKCγ isoforms, but with significantly reduced potency (IC50 = 30-42 µM). Has reduced inhibitory activity on PKCε, PKCη, and PKCξ (IC50 = 80-100 µM). Also known to inhibit CaM kinase III (IC50 = 5.3 µM) ...
The Amino Acids
... • Proteins are polymers of amino acids • There are 20 different amino acids that make up proteins • All of them have similar structures • Amino acids joined together end-to-end • Special name for this bond - Peptide Bond • Virtually unlimited number of proteins ...
... • Proteins are polymers of amino acids • There are 20 different amino acids that make up proteins • All of them have similar structures • Amino acids joined together end-to-end • Special name for this bond - Peptide Bond • Virtually unlimited number of proteins ...
Chapter_5 mod by rauch
... the hydrophilic heads are on the outside in contact with the aqueous solution and the hydrophobic tails from the core. The phospholipid bilayer forms a barrier between the cell and the ...
... the hydrophilic heads are on the outside in contact with the aqueous solution and the hydrophobic tails from the core. The phospholipid bilayer forms a barrier between the cell and the ...
Modification of Galactose Oxidase to
... were then loaded onto a diethylaminoethyl ± cellulose column and eluted with sodium phosphate (NaPi; 50 mM, pH 7.0) at 4 8C. The active fractions were pooled and concentrated in a stirred ultrafiltration cell (Amicon Corp., Beverly, MA). The concentrated samples were dialyzed against NaPi (10 mM, pH ...
... were then loaded onto a diethylaminoethyl ± cellulose column and eluted with sodium phosphate (NaPi; 50 mM, pH 7.0) at 4 8C. The active fractions were pooled and concentrated in a stirred ultrafiltration cell (Amicon Corp., Beverly, MA). The concentrated samples were dialyzed against NaPi (10 mM, pH ...
Bottromycin
Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.