p53, the Cellular Gatekeeper Review for Growth and Division
... The p53 gene and its protein product have become the center of intensive study ever since it became clear that slightly more than 50% of human cancers contain mutations in this gene. An extensive database (Hollstein et al., 1994) catalogs these mutations in more than 50 different cell and tissue typ ...
... The p53 gene and its protein product have become the center of intensive study ever since it became clear that slightly more than 50% of human cancers contain mutations in this gene. An extensive database (Hollstein et al., 1994) catalogs these mutations in more than 50 different cell and tissue typ ...
Different susceptibility of two animal species infected with isogenic
... has been determined in a single model of animal virulence, usually in mice or guinea pigs. This use of a single animal model reflects practicalities in terms of cost and time of using more than one animal host under biological containment for investigating a chronic disease, as well as an underlying ...
... has been determined in a single model of animal virulence, usually in mice or guinea pigs. This use of a single animal model reflects practicalities in terms of cost and time of using more than one animal host under biological containment for investigating a chronic disease, as well as an underlying ...
An alternative, arginase-independent pathway for arginine Kluyveromyces lactis involves metabolism in
... (Klku80Δ KlCAR1 reference strain) and IMS0367 (Klcar1Δ Arg+) were grown in aerobic bioreactor batch cultures on chemically defined medium with glucose and arginine as sole nitrogen source (Fig. 4). The specific growth rate of the arginase-negative strain was around fourfold lower than that of the re ...
... (Klku80Δ KlCAR1 reference strain) and IMS0367 (Klcar1Δ Arg+) were grown in aerobic bioreactor batch cultures on chemically defined medium with glucose and arginine as sole nitrogen source (Fig. 4). The specific growth rate of the arginase-negative strain was around fourfold lower than that of the re ...
MyGene.info Documentation
... MyGene.info provides simple-to-use REST web services to query/retrieve gene annotation data. It’s designed with simplicity and performance emphasized. A typical use case is to use it to power a web application which requires querying genes and obtaining common gene annotations. For example, MyGene.i ...
... MyGene.info provides simple-to-use REST web services to query/retrieve gene annotation data. It’s designed with simplicity and performance emphasized. A typical use case is to use it to power a web application which requires querying genes and obtaining common gene annotations. For example, MyGene.i ...
Enzymatic activation of sulfur for incorporation into biomolecules in
... although via more indirect pathways (see below). The central importance of IscS in E. coli has motivated innumerable searches for sequence homologs in other organisms and often iscS-type genes can be identified by the encoded IscS protein signature motifs and the neighborhood to other isc-type compo ...
... although via more indirect pathways (see below). The central importance of IscS in E. coli has motivated innumerable searches for sequence homologs in other organisms and often iscS-type genes can be identified by the encoded IscS protein signature motifs and the neighborhood to other isc-type compo ...
Effect of the allelic variants of aldehyde
... Alcoholism is a complex behavioural disorder. Molecular genetics studies have identified numerous candidate genes associated with alcoholism. It is crucial to verify the disease susceptibility genes by correlating the pinpointed allelic variations to the causal phenotypes. Alcohol dehydrogenase (ADH ...
... Alcoholism is a complex behavioural disorder. Molecular genetics studies have identified numerous candidate genes associated with alcoholism. It is crucial to verify the disease susceptibility genes by correlating the pinpointed allelic variations to the causal phenotypes. Alcohol dehydrogenase (ADH ...
Appaloosa Inheritance
... perhaps in this order of dominance, but not necessarily so as certain Leopards and Spotted Blankets could alternate. These markings are seldom claimed to be high colour producers hence their lower case. The chances of each being found in homozygous form is slight because the interbreeding of all the ...
... perhaps in this order of dominance, but not necessarily so as certain Leopards and Spotted Blankets could alternate. These markings are seldom claimed to be high colour producers hence their lower case. The chances of each being found in homozygous form is slight because the interbreeding of all the ...
Anti-Rat Ciliary Neurotrophic Factor (CNTF) Developed in Goat IgG
... Anti-Rat Ciliary Neurotrophic Factor was developed in goat using recombinant, rat ciliary neurotrophic factor (CNTF), expressed in E. coli, as the immunogen. The antibody is purified by Protein G affinity chromatography. Goat Anti-Rat CNTF is provided lyophilized from phosphate buffered saline, to w ...
... Anti-Rat Ciliary Neurotrophic Factor was developed in goat using recombinant, rat ciliary neurotrophic factor (CNTF), expressed in E. coli, as the immunogen. The antibody is purified by Protein G affinity chromatography. Goat Anti-Rat CNTF is provided lyophilized from phosphate buffered saline, to w ...
Protein Purification by Inverse Transition Cycling
... ions and their concentrations). Examples of the effects of these two factors on the Tt for a given ELP construct are shown in Figures 2 and 3. Because the Tt decreases logarithmically with increasing concentration (Fig. 2), the effect of ELP concentration is of greatest practical importance at conce ...
... ions and their concentrations). Examples of the effects of these two factors on the Tt for a given ELP construct are shown in Figures 2 and 3. Because the Tt decreases logarithmically with increasing concentration (Fig. 2), the effect of ELP concentration is of greatest practical importance at conce ...
Tadashi Inagami, Deng-Fu Guo and Yutaka Kitami
... Journal of hypertension 1994, Vol. 12 (Suppl 10) acid sequence. This aniino acid sequence differed from the bovine adrenal AT 1 amino acid sequence by 8%. The difference could have been due to either different species or organ-dependent AT 1 subtypes. To resolve this question, AT 1 receptor from rat ...
... Journal of hypertension 1994, Vol. 12 (Suppl 10) acid sequence. This aniino acid sequence differed from the bovine adrenal AT 1 amino acid sequence by 8%. The difference could have been due to either different species or organ-dependent AT 1 subtypes. To resolve this question, AT 1 receptor from rat ...
Functional Plant Biology
... expression levels among these genes in RNA extracts of nodules grown in N-depleted conditions (see Supplementary methods available as an Accessory publication to this paper). As shown in Table 2, expression of a GOGAT gene (gltS ss) was very high relative to nifH expression (0.68). Glutamine synthet ...
... expression levels among these genes in RNA extracts of nodules grown in N-depleted conditions (see Supplementary methods available as an Accessory publication to this paper). As shown in Table 2, expression of a GOGAT gene (gltS ss) was very high relative to nifH expression (0.68). Glutamine synthet ...
Principles of BIOCHEMISTRY
... • a precursor of bile acids • a precursor of vitamin D • important component of many mammalian membranes (modulates the fluidity) ...
... • a precursor of bile acids • a precursor of vitamin D • important component of many mammalian membranes (modulates the fluidity) ...
PDF
... Asker and Jerling 1992; Koltunow 1993). As apomictic reproduction entails the development of an embryo from a cell with a somatic chromosome number, several ways exist to produce embryos of apomictic origin. The simplest pathway avoids the production of a gametophyte, and a maternal embryo originate ...
... Asker and Jerling 1992; Koltunow 1993). As apomictic reproduction entails the development of an embryo from a cell with a somatic chromosome number, several ways exist to produce embryos of apomictic origin. The simplest pathway avoids the production of a gametophyte, and a maternal embryo originate ...
Flavonoids in Biological System
... Flavonoids are becoming very popular because they have many health Promoting effects. For examples : anti-allergic, anti-cancer, antioxidant, anti-inflammatory and anti-viral. ...
... Flavonoids are becoming very popular because they have many health Promoting effects. For examples : anti-allergic, anti-cancer, antioxidant, anti-inflammatory and anti-viral. ...
PDF
... et al., 1959; Ede and Kelly, 1964a,b; MacCabe and Abbott, 1974). Although talpid became extinct, the study of the genetic and molecular etiology of the talpid2 and talpid3 phenotypes continues. talpid2 and talpid3 have similar limb phenotypes, yet the craniofacial phenotypes are distinct. talpid3 ha ...
... et al., 1959; Ede and Kelly, 1964a,b; MacCabe and Abbott, 1974). Although talpid became extinct, the study of the genetic and molecular etiology of the talpid2 and talpid3 phenotypes continues. talpid2 and talpid3 have similar limb phenotypes, yet the craniofacial phenotypes are distinct. talpid3 ha ...
Cell Chemistry and Structure
... Know that the energy releasing reactions are linked to the formation of ATP from ADP and phosphate. Know that ATP is an energy rich compound, which can break down to ADP and phosphate, releasing energy for use in energy requiring processes. Be able to give examples of energy requiring processes driv ...
... Know that the energy releasing reactions are linked to the formation of ATP from ADP and phosphate. Know that ATP is an energy rich compound, which can break down to ADP and phosphate, releasing energy for use in energy requiring processes. Be able to give examples of energy requiring processes driv ...
Minimum SNPs version 2043 user manual
... the DNA. In principle, SNPs could be bi-, tri-, or tetra-allelic polymorphisms. However, triallelic and tetra- allelic SNPs are rare and so SNPs are sometimes simply referred to as biallelic markers. However, we have identified two tri-allelic SNP that have proved very useful in genotyping Staphyloc ...
... the DNA. In principle, SNPs could be bi-, tri-, or tetra-allelic polymorphisms. However, triallelic and tetra- allelic SNPs are rare and so SNPs are sometimes simply referred to as biallelic markers. However, we have identified two tri-allelic SNP that have proved very useful in genotyping Staphyloc ...
Persistence and dispersion of Acinetobacter spp. in the urban water
... genus Acinetobacter should comprise only oxidase-negative strains. This division was supported by the use of several phenotypic tests, which have now been used for over three decades as the basis for inclusion of individual isolates within the genus (Bergogne-Berezin & Towner, 1996). ...
... genus Acinetobacter should comprise only oxidase-negative strains. This division was supported by the use of several phenotypic tests, which have now been used for over three decades as the basis for inclusion of individual isolates within the genus (Bergogne-Berezin & Towner, 1996). ...
Risk Assessment and Risk Management Plan
... Environment Minister, State and Territory Governments, GTTAC, and Commonwealth agencies (see Regulation 9 of Gene Technology Regulations 2001) and local Councils where the release is proposed were considered and assessed by the Regulator. 11. The legislation requires the Regulator to consider a numb ...
... Environment Minister, State and Territory Governments, GTTAC, and Commonwealth agencies (see Regulation 9 of Gene Technology Regulations 2001) and local Councils where the release is proposed were considered and assessed by the Regulator. 11. The legislation requires the Regulator to consider a numb ...
Genomic dissection of plant development and its
... shooting lines also tend to be early for other stages. Another peculiarity is that in the case of RIP correlation coefficients were negative for all other developmental stages. Together with the relatively low coefficient of variation for MAT, this indicates that the time of maturity may be predeter ...
... shooting lines also tend to be early for other stages. Another peculiarity is that in the case of RIP correlation coefficients were negative for all other developmental stages. Together with the relatively low coefficient of variation for MAT, this indicates that the time of maturity may be predeter ...
Human RIF1 and protein phosphatase 1 stimulate DNA replication
... accompanied by a change in replication fork progression as reported in other instances of reduced origin frequency, or was there a different effect due to the concomitant effects on replication timing? This point should at least be discussed. Minor issues: 1/ It seems from the Methodology section th ...
... accompanied by a change in replication fork progression as reported in other instances of reduced origin frequency, or was there a different effect due to the concomitant effects on replication timing? This point should at least be discussed. Minor issues: 1/ It seems from the Methodology section th ...