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A Genome-Wide Survey of the NAC Transcription
A Genome-Wide Survey of the NAC Transcription

... To determine the phylogenetic relationships of the NAC family genes in rice and citrus, a multiple sequence alignment was performed using amino acid sequences in the NAC domain. This analysis revealed that those amino acid residues which might be involved in some form of physical contact with DNA ar ...
color info - Bedonna`s Performance Horses
color info - Bedonna`s Performance Horses

... Because I study color genetics, and have lots of color in my breeding program, I get asked LOTS of questions about colors and color possibilities for foals. I used to include most of this info in my breeding agreements, but it added too much length to the contract, so I am going to have it all liste ...
Ribosomopathies: human disorders of ribosome
Ribosomopathies: human disorders of ribosome

... include anemia, thrombocytopenia, short stature, and skeletal abnormalities.41 Patients with SDS are also at an increased risk for myelodysplasia and malignant transformation. Supportive measures for patients with SDS include pancreatic enzymes, antibiotics, transfusions, and granulocyte colony-stim ...
Ribosomopathies: human disorders of ribosome
Ribosomopathies: human disorders of ribosome

... include anemia, thrombocytopenia, short stature, and skeletal abnormalities.41 Patients with SDS are also at an increased risk for myelodysplasia and malignant transformation. Supportive measures for patients with SDS include pancreatic enzymes, antibiotics, transfusions, and granulocyte colony-stim ...
Cross-Product Extensions of the Gene Ontology
Cross-Product Extensions of the Gene Ontology

Yet viruses cannot be included in the tree of life - Université Paris-Sud
Yet viruses cannot be included in the tree of life - Université Paris-Sud

... that are supposed to reflect organismal evolution. Whether this molecular phylogenetic tree truly reflects the most important lines of organismal evolution is a matter of discussion but, in practice, it is helpful and the basis of natural systematics (for an example, see the Tree of Life Web Project ...
Determination of Nutrient Contents and Amino acid Composition of
Determination of Nutrient Contents and Amino acid Composition of

... production fix. Effect of Cu2+ at the expense of VEGF is not mediated by H2O2 but bound in thiol-redox status in the cell. Histological analyzes were performed on the edge of the wound tissue is known that the CuSO4-treatment not only speed up the process of wound closure but also the quality of dif ...
Genetic defects causing mitochondrial respiratory
Genetic defects causing mitochondrial respiratory

... to be a potentially important level of accumulation of mitochondrial mutations that can exceed the threshold for clinical consequence. In summary, where the metabolic disorder is due to a defect of a mitochondrially encoded gene, the clinical consequences of that mtDNA mutation are a function of the ...
CHROMOSOMES AND DISEASE
CHROMOSOMES AND DISEASE

Article Fitness Trade-Offs Determine the Role of the Molecular
Article Fitness Trade-Offs Determine the Role of the Molecular

Figure 4-24, step 1
Figure 4-24, step 1

... Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings ...
Imprinting and Seed Development
Imprinting and Seed Development

... duce seeds asexually by apomixis, which exists in several different forms (Nogler, 1984; Koltunow, 1993; Bicknell and Koltunow, 2004). During gametophytic apomixis, the megagametophyte develops from an unreduced megaspore or from a somatic cell inside the ovule. The diploid embryo then develops from ...
a role for mitochondrial enzymes in inherited neoplasia and beyond
a role for mitochondrial enzymes in inherited neoplasia and beyond

... known inherited kidney cancer syndromes (TABLE 2). The apparently dominantly inherited tumours are solitary and aggressive, and usually occur early in life (between the ages of 26 and 48 years). A key feature of these tumours is their histopathology — all component renal carcinomas that have been ex ...
Supporting Information Parfenov et al. 10.1073/pnas.1416074111
Supporting Information Parfenov et al. 10.1073/pnas.1416074111

... million reads mapped) across 70% of the patient samples as not expressed (white with black outline in Fig. 2 and Figs. S4 and S5). For graphical representation of exon expression levels, we mean-centered the RPKM values and divided by their SD for each exon. The lengths of the composite exons were t ...
Failures in Mitochondrial tRNA and tRNA Metabolism
Failures in Mitochondrial tRNA and tRNA Metabolism

... America and the world. In particular, hypertension affects ⬇1 billion individuals worldwide and 130 million in China.1 The etiology of cardiovascular disease is not well understood because of the multifactorial causes. Cardiovascular disease can be caused by a single gene or multifactorial condition ...
(F193L) in the KCNQ1 gene associated with long
(F193L) in the KCNQ1 gene associated with long

Introduction to Protein Summit 2.0: continued exploration of the
Introduction to Protein Summit 2.0: continued exploration of the

INTERNATIONAL NONPROPRIETARY NAMES (INN) FOR
INTERNATIONAL NONPROPRIETARY NAMES (INN) FOR

... substance would be recognized globally by a unique name. These INNs do not give proprietary rights, unlike a trade mark, and can be used freely as they are public property. INNs have been assigned to biological products since the early days of the INN Programme. As well as many names for individual ...
How to order genetic testing for Hemophilia A and B
How to order genetic testing for Hemophilia A and B

... Most mutations that cause hemophilia B are little alterations in genetic code, which is why sequencing will detect pathogenic mutations in 97% to100% of individuals with a clinical diagnosis of hemophilia B. However, while this method allows us to see small mutations in the DNA sequence, it is too f ...
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

... 2. Describe techniques used to characterize genome 3. Describe bacterial genomes and compare them with those of archaea and eukaryotes 4. Describe horizontal gene transfer and explain how to determine if it has taken place 5. Describe the difference between the core genome and pan genome of a bacter ...
Multiple sequence alignment: outline
Multiple sequence alignment: outline

... representation of the MSA. Sequences can be generated from the HMM by starting at the beginning state labeled BEG and then by following anyone of many pathways from one type of sequence variation to another (states) along the state transition arrows and terminating in the ending state labeled END. A ...
Atomistic understanding of kinetic pathways for single base
Atomistic understanding of kinetic pathways for single base

Understanding the Scurred condition in Polled Cattle
Understanding the Scurred condition in Polled Cattle

... Most calves that are horned can be identified at birth or shortly after, and almost always by weaning time. Distinguishing between smooth-polled and scurred-polled is more difficult. Scurs, a rudimentary horn growth, are often not seen until cattle are nearly a year old or sometimes even older. Scur ...
Specification of floral organs in Arabidopsis
Specification of floral organs in Arabidopsis

... Arabidopsis and what is found in other angiosperms, however, is the apparent absence of bona fide A function genes in many flowering plants (Litt and Kramer, 2010). This finding has led to a re-evaluation of the concept of A function and to the proposal of a modified model for floral organ identity ...
Disintegrin, hemorrhagic, and proteolytic activities of Mohave
Disintegrin, hemorrhagic, and proteolytic activities of Mohave

... mg/kg). Both subunits must be present to produce Mojave toxin, which can increase the venom toxicity significantly. Although specimens of C. s. scutulatus sampled throughout the majority of its range contain Mojave toxin, there are populations in central Arizona that do not express the neurotoxic co ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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