Structure and function of the chloroplast signal recognition particle
... Abstract The targeting of proteins, including the insertion and translocation of proteins in or across membranes, is a fundamental process within a cell, and a variety of specialized mechanisms for protein transport have been developed during evolution. The signal recognition particle (SRP) is found ...
... Abstract The targeting of proteins, including the insertion and translocation of proteins in or across membranes, is a fundamental process within a cell, and a variety of specialized mechanisms for protein transport have been developed during evolution. The signal recognition particle (SRP) is found ...
Protein Structure Prediction Based on Neural Networks
... the spatial regions between the query protein and the template protein are the same. However, this is not the case in reality, especially when the template protein and the query protein have partly different folds or different functions. For example, the prediction becomes complex, when the homology ...
... the spatial regions between the query protein and the template protein are the same. However, this is not the case in reality, especially when the template protein and the query protein have partly different folds or different functions. For example, the prediction becomes complex, when the homology ...
Enzyme promiscuity: evolutionary and mechanistic aspects
... the two need not be mutually exclusive [33]. The promiscuous, accidental functions of a protein are highly plastic. They can be shaped through mutations that dramatically increase or decrease them. However, these mutations need not have a large effect on the protein’s original activity. Indeed, th ...
... the two need not be mutually exclusive [33]. The promiscuous, accidental functions of a protein are highly plastic. They can be shaped through mutations that dramatically increase or decrease them. However, these mutations need not have a large effect on the protein’s original activity. Indeed, th ...
Substrate specificity of protein kinase A in reaction with
... were provided by Hanks, Quinn and Hunter (Hanks et al, 1988). The common motif for all protein kinases is the homologous “kinase domain”, also known as the “catalytic domain”. This part of these enzymes consists of 250-300 amino acid residues. The kinase domain contains 12 conserved subdomains and i ...
... were provided by Hanks, Quinn and Hunter (Hanks et al, 1988). The common motif for all protein kinases is the homologous “kinase domain”, also known as the “catalytic domain”. This part of these enzymes consists of 250-300 amino acid residues. The kinase domain contains 12 conserved subdomains and i ...
Intrinsic Disorder in Cell-signaling and Cancer
... disordered regions in this dataset (Figure 2(b)). The analysis on a per residue basis (Figure 2(c)), however, also indicated a large amount of disorder, implying that the increased length does not completely explain the higher percentage of predicted disorder in this category. To test the possibilit ...
... disordered regions in this dataset (Figure 2(b)). The analysis on a per residue basis (Figure 2(c)), however, also indicated a large amount of disorder, implying that the increased length does not completely explain the higher percentage of predicted disorder in this category. To test the possibilit ...
Separating spandrels from phenotypic targets of selection
... existing method to verify which phenotypic changes were directly targeted by selection. The problem is that correlations between traits make it difficult to distinguish between direct and indirect selection. A phenotype is a direct target of selection when that trait in particular was shaped by sele ...
... existing method to verify which phenotypic changes were directly targeted by selection. The problem is that correlations between traits make it difficult to distinguish between direct and indirect selection. A phenotype is a direct target of selection when that trait in particular was shaped by sele ...
Role of Dietary Protein in Post-Exercise Muscle Reconditioning
... (EAA) concentrations (with leucine in particular) stimulates muscle protein synthesis rates. Such a postprandial increase in muscle protein synthesis rate will typically last for 2–3 h after meal ingestion. It is obvious that amino acids are much more than simply precursors of de novo muscle protein ...
... (EAA) concentrations (with leucine in particular) stimulates muscle protein synthesis rates. Such a postprandial increase in muscle protein synthesis rate will typically last for 2–3 h after meal ingestion. It is obvious that amino acids are much more than simply precursors of de novo muscle protein ...
Proteins are made of chains of amino acids
... Essential amino acids and nutrition • Consider why protein is needed and what amino acids and proteins are used for in the body. Describe the symptoms you would expect a person with protein deficiency to have. • Look at Table 1. Which amino acids does corn lack (not have)? Which amino acids do bean ...
... Essential amino acids and nutrition • Consider why protein is needed and what amino acids and proteins are used for in the body. Describe the symptoms you would expect a person with protein deficiency to have. • Look at Table 1. Which amino acids does corn lack (not have)? Which amino acids do bean ...
Prediction of B cell epitopes
... antigen complexes in the PDB The data set has been used for developing a method for predictions of discontinuous B cell epitopes Since about 30 of the PDB entries represented Lysozyme, I have used homology grouping (25 groups of non-homologous antigens) and 5 fold cross-validation for training o ...
... antigen complexes in the PDB The data set has been used for developing a method for predictions of discontinuous B cell epitopes Since about 30 of the PDB entries represented Lysozyme, I have used homology grouping (25 groups of non-homologous antigens) and 5 fold cross-validation for training o ...
Organelle origins: Energy-producing symbionts
... with mitochondria, but not with a-proteobacteria. Mitochondria and hydrogenosomes must thus have a common evolutionary history — but at what point did their lineages diverge? Hydrogenosomes may have evolved from an endosymbiont that was ancestral to mitochondria [8], but this seems unlikely because ...
... with mitochondria, but not with a-proteobacteria. Mitochondria and hydrogenosomes must thus have a common evolutionary history — but at what point did their lineages diverge? Hydrogenosomes may have evolved from an endosymbiont that was ancestral to mitochondria [8], but this seems unlikely because ...
Co-opting sulphur-carrier proteins from primary metabolic pathways
... Sulphur is an essential element for life and is ubiquitous in living systems1,2. Yet how the sulphur atom is incorporated into many sulphur-containing secondary metabolites is poorly understood. For bond formation between carbon and sulphur in primary metabolites, the major ionic sulphur sources are ...
... Sulphur is an essential element for life and is ubiquitous in living systems1,2. Yet how the sulphur atom is incorporated into many sulphur-containing secondary metabolites is poorly understood. For bond formation between carbon and sulphur in primary metabolites, the major ionic sulphur sources are ...
... Most enzymes are pH dependent for their activity. Usually they have a pH-optimum which is suited to the environment in which they are generally found. Reasons for this may be that the amino acids in the active site need to be in a certain state of ionization to be active, that the substrate has to ...
Standard for the presentation of nucleotide and amino acid
... “amino acids” are those L-amino acids commonly found in naturally occurring proteins and are listed in Appendix 2, Table 3. Those amino acid sequences containing at least one D-amino acid are not intended to be embraced by this definition. Any amino acid sequence that contains post-translationally m ...
... “amino acids” are those L-amino acids commonly found in naturally occurring proteins and are listed in Appendix 2, Table 3. Those amino acid sequences containing at least one D-amino acid are not intended to be embraced by this definition. Any amino acid sequence that contains post-translationally m ...
slides - DTU CBS
... CENTER FOR BIOLOGICAL SEQUENCE ANALYSIS TECHNICAL UNIVERSITY OF DENMARK DTU ...
... CENTER FOR BIOLOGICAL SEQUENCE ANALYSIS TECHNICAL UNIVERSITY OF DENMARK DTU ...
Full Text - Journal of Pharmaceutical, Chemical and
... same subclades. For example, Gossypium arboretum and Gossypium hirsutum are Malvaceae plants, the ANR proteins GaANR and GhANR shared the same subclade; ANR proteins from Prunus cerasifera and Rubus idaeus that belongs to Rosaceae were classified into the same subclades. The phylogenetic analysis in ...
... same subclades. For example, Gossypium arboretum and Gossypium hirsutum are Malvaceae plants, the ANR proteins GaANR and GhANR shared the same subclade; ANR proteins from Prunus cerasifera and Rubus idaeus that belongs to Rosaceae were classified into the same subclades. The phylogenetic analysis in ...
Investigating semantic similarity measures across the
... another term. These orphan terms within GO need to be provided with links for the purposes of our investigation. We simply linked them directly to the root of their taxonomy. This is perhaps semantically impoverished (for example, a “granum”, (GO:0009542) becomes a kind of “cellular component”, (GO: ...
... another term. These orphan terms within GO need to be provided with links for the purposes of our investigation. We simply linked them directly to the root of their taxonomy. This is perhaps semantically impoverished (for example, a “granum”, (GO:0009542) becomes a kind of “cellular component”, (GO: ...
Chemical synthesis of proteins
... for the solid-phase chemical synthesis of proteins. The first protocol uses the tertiary-butyloxycarbonyl (Boc) group for Na-amino protection. The Boc group is typically removed by trifluoroacetic acid (TFA) and the free N terminus is neutralized by a tertiary amine. The peptide is removed from the ...
... for the solid-phase chemical synthesis of proteins. The first protocol uses the tertiary-butyloxycarbonyl (Boc) group for Na-amino protection. The Boc group is typically removed by trifluoroacetic acid (TFA) and the free N terminus is neutralized by a tertiary amine. The peptide is removed from the ...
Identification of surface proteins in Enterococcus - UiO
... to mucosal and epithelial surfaces have been reported [2]. In addition to involvement in adhesion, surface proteins may affect virulence in other ways, for example by involvement in cell-cell signalling [9], interactions with the host immune system, sensing environmental factors, or protection from ...
... to mucosal and epithelial surfaces have been reported [2]. In addition to involvement in adhesion, surface proteins may affect virulence in other ways, for example by involvement in cell-cell signalling [9], interactions with the host immune system, sensing environmental factors, or protection from ...
Characterisation of hexon and fibre genes of a novel strain of
... patterns of Ad11, Ad35, and M86, using the percentage of pair wise co-migrating restriction fragments of a pair divided by the total number of bands in the pair. The isolate (M86) showed 98% and 88% homology with Ad11 and Ad35, respectively (fig 1). Higher homology of the new strain in restriction e ...
... patterns of Ad11, Ad35, and M86, using the percentage of pair wise co-migrating restriction fragments of a pair divided by the total number of bands in the pair. The isolate (M86) showed 98% and 88% homology with Ad11 and Ad35, respectively (fig 1). Higher homology of the new strain in restriction e ...
Protein-protein interaction networks (I): data preprocessing
... expensive to get. Taking interactions that are supported by two or more experimental techniques is a third method. If an interaction is supported by several methods it is more likely to be true. It will however result in ignoring those true interactions that are only supported by one technique (for ...
... expensive to get. Taking interactions that are supported by two or more experimental techniques is a third method. If an interaction is supported by several methods it is more likely to be true. It will however result in ignoring those true interactions that are only supported by one technique (for ...
IdaPro® Milk Proteins - SupplySide Storefronts
... Amino Acid Profile: Milk Proteins vs Whey Proteins In testing of three market available WPC-80 samples and three IdaPro ® MPI-85 samples, results of assays conducted by independent testing laboratories showed that the Amino Acid (AA) profiles are very similar.6 The slight differences in Essential AA ...
... Amino Acid Profile: Milk Proteins vs Whey Proteins In testing of three market available WPC-80 samples and three IdaPro ® MPI-85 samples, results of assays conducted by independent testing laboratories showed that the Amino Acid (AA) profiles are very similar.6 The slight differences in Essential AA ...
Identification of prokaryotic homologues indicates an endosymbiotic
... The cyanobacterial PTOX homologues are, at their Nterminus, shorter than the eukaryotic PTOX sequences, which is in part explained by the lack of an organelle targeting sequence. Fig. 3 shows a multiple sequence alignment of cyanobacterial predicted PTOXs with the Cterminal part of known PTOXs. The ...
... The cyanobacterial PTOX homologues are, at their Nterminus, shorter than the eukaryotic PTOX sequences, which is in part explained by the lack of an organelle targeting sequence. Fig. 3 shows a multiple sequence alignment of cyanobacterial predicted PTOXs with the Cterminal part of known PTOXs. The ...
Full-Text PDF
... results were interpreted in the context of the docking results. The results suggest that an extended surface along the active site cleft is involved in binding of a protein substrate. Furthermore, it appears that a number of hydrophobic and aromatic residues are important for interacting with Z-QG, ...
... results were interpreted in the context of the docking results. The results suggest that an extended surface along the active site cleft is involved in binding of a protein substrate. Furthermore, it appears that a number of hydrophobic and aromatic residues are important for interacting with Z-QG, ...
Structure of a Plasmodium yoelii gene
... for 2h at 42 °C. Hybridizations were done under the same conditions using a 1 ;
... for 2h at 42 °C. Hybridizations were done under the same conditions using a 1 ;