Profile TildeCRF: a new tool for protein homology detection
... foundations for modern biology and genetics. Charles Darwin described the mechanism of natural selection, whereby individuals that are best adapted to their environment are more likely to survive and reproduce, passing their characteristics on to their offspring, while maladapted individuals tend to ...
... foundations for modern biology and genetics. Charles Darwin described the mechanism of natural selection, whereby individuals that are best adapted to their environment are more likely to survive and reproduce, passing their characteristics on to their offspring, while maladapted individuals tend to ...
Paenibacillus xanthinilyticus sp. nov., isolated from agricultural soil
... of diversity of agroecosystems. A standard dilution plating technique on R2A agar (Difco) was used to isolate bacteria from an agricultural soil cultivated with Chinese cabbage (Brassica campestris L.). After plating, cultures were incubated at 28 8C for 7 days, and a white-pigmented bacterial strai ...
... of diversity of agroecosystems. A standard dilution plating technique on R2A agar (Difco) was used to isolate bacteria from an agricultural soil cultivated with Chinese cabbage (Brassica campestris L.). After plating, cultures were incubated at 28 8C for 7 days, and a white-pigmented bacterial strai ...
A Mutation in LTBP2 Causes Congenital Glaucoma in
... linked short tandem repeat (STR) loci to the candidate gene, LTBP2. A 4 base-pair insertion was identified in exon 8 of LTBP2 in affected individuals that generates a frame shift that completely alters the downstream open reading frame and eliminates functional domains. Thus, we describe the first s ...
... linked short tandem repeat (STR) loci to the candidate gene, LTBP2. A 4 base-pair insertion was identified in exon 8 of LTBP2 in affected individuals that generates a frame shift that completely alters the downstream open reading frame and eliminates functional domains. Thus, we describe the first s ...
using the crispr/cas9 gene editing tool to develop a cure for
... quickly improved the use of CRISPR, although there are some variations in how it is used. The most important component is the CRISPR RNA molecule, which includes two types of RNA: programmable guide RNA and tracer RNA. These two parts typically function as two separate molecules, but Jennifer Doudna ...
... quickly improved the use of CRISPR, although there are some variations in how it is used. The most important component is the CRISPR RNA molecule, which includes two types of RNA: programmable guide RNA and tracer RNA. These two parts typically function as two separate molecules, but Jennifer Doudna ...
Meiosis and Sexual Life Cycles
... Transmitting chromosomes and genetic information from generation to generation is equally important. A critical role of heredity is to maintain and obtain variation among members of a species. These variations are the result of the specific genes we inherit from our parents. We did not always know t ...
... Transmitting chromosomes and genetic information from generation to generation is equally important. A critical role of heredity is to maintain and obtain variation among members of a species. These variations are the result of the specific genes we inherit from our parents. We did not always know t ...
transposon
... x M female crosses, but not by M male x P female crosses. A P strain carries 30-50 copies of the P element, about a third of them full length. The elements are absent from M strains. In a P strain, the elements are carried as inert components of the genome. But they become activated to transpose w ...
... x M female crosses, but not by M male x P female crosses. A P strain carries 30-50 copies of the P element, about a third of them full length. The elements are absent from M strains. In a P strain, the elements are carried as inert components of the genome. But they become activated to transpose w ...
The Evolution of CONSTANS-Like Gene Families
... The CO (CONSTANS) gene of Arabidopsis has an important role in the regulation of flowering by photoperiod. CO is part of a gene family with 17 members that are subdivided into three classes, termed Group I to III here. All members of the family have a CCT (CO, CO-like, TOC1) domain near the carboxy ...
... The CO (CONSTANS) gene of Arabidopsis has an important role in the regulation of flowering by photoperiod. CO is part of a gene family with 17 members that are subdivided into three classes, termed Group I to III here. All members of the family have a CCT (CO, CO-like, TOC1) domain near the carboxy ...
Assessing in silico the recruitment and functional spectrum of
... For the evolution of a novel SM pathway, it is generally assumed that it arises through the acquisition of genes from the PM repertoire [6, 9]. According to this theory, after initial gene duplication of the PM predecessor, subsequent mutations shape the biological activity of the gene copy in a way ...
... For the evolution of a novel SM pathway, it is generally assumed that it arises through the acquisition of genes from the PM repertoire [6, 9]. According to this theory, after initial gene duplication of the PM predecessor, subsequent mutations shape the biological activity of the gene copy in a way ...
Mitochondrial cytopathy in adults: What we know so far
... patients have minimal objective findings, possibly because fatigability is difficult to quantify in a physician’s office. Only in severe cases or late in the course of the illness are gross muscle bulk and strength reduced. However, a careful physical examination early on may reveal doughy muscle co ...
... patients have minimal objective findings, possibly because fatigability is difficult to quantify in a physician’s office. Only in severe cases or late in the course of the illness are gross muscle bulk and strength reduced. However, a careful physical examination early on may reveal doughy muscle co ...
20060710_GOannotCamp_Stanford
... Conclusions – Metrics to monitor breadth: 1. How many genes does your genome have? Best estimate of protein or functional RNA genes. Pseudogenes do NOT count. 2. How many genes have any GO annotation? Genes with ND annotations will be counted for this metric since the presence of unknown annotations ...
... Conclusions – Metrics to monitor breadth: 1. How many genes does your genome have? Best estimate of protein or functional RNA genes. Pseudogenes do NOT count. 2. How many genes have any GO annotation? Genes with ND annotations will be counted for this metric since the presence of unknown annotations ...
transposon
... x M female crosses, but not by M male x P female crosses. A P strain carries 30-50 copies of the P element, about a third of them full length. The elements are absent from M strains. In a P strain, the elements are carried as inert components of the genome. But they become activated to transpose w ...
... x M female crosses, but not by M male x P female crosses. A P strain carries 30-50 copies of the P element, about a third of them full length. The elements are absent from M strains. In a P strain, the elements are carried as inert components of the genome. But they become activated to transpose w ...
0 - Microbiology
... markers into recipient cells. The isolation of many more Hfr strains with different origines led rapidly to the construction of increasingly complete linkage maps, such as that compiled by Taylor & Trotter (1972), for markers located on the circular chromosome of E. coli. Since, under favourable con ...
... markers into recipient cells. The isolation of many more Hfr strains with different origines led rapidly to the construction of increasingly complete linkage maps, such as that compiled by Taylor & Trotter (1972), for markers located on the circular chromosome of E. coli. Since, under favourable con ...
News from the west: Ancient DNA from a French megalithic burial
... of significant post-Neolithic migrations, they proposed a Paleolithic ancestry for modern Europeans. Nonetheless, two recent publications (Bramanti et al., 2009; Malmström et al., 2009) reported sequences from late European hunter-gatherers that demonstrated genetic differentiation between ancient h ...
... of significant post-Neolithic migrations, they proposed a Paleolithic ancestry for modern Europeans. Nonetheless, two recent publications (Bramanti et al., 2009; Malmström et al., 2009) reported sequences from late European hunter-gatherers that demonstrated genetic differentiation between ancient h ...
Building proteins from C, coordinates using the dihedral probability
... may enable complete protein structures to be built from the C, coordinates of a lattice representation. Our work was motivated by both of these factors: the desire to build full protein structures from lattice structures, and to provide a means for evaluating different lattice conformations. In addi ...
... may enable complete protein structures to be built from the C, coordinates of a lattice representation. Our work was motivated by both of these factors: the desire to build full protein structures from lattice structures, and to provide a means for evaluating different lattice conformations. In addi ...
and Medium-Chain-Length Fatty Acids
... primer, as suggested by the previous observation of d8-Val incorporation into d7-i10:0 (Walters and Steffens, 1990). In accordance with this, the FAS-like extension of d9-i5:0 (d93-methylbutyric acid), which is derived from d10-Leu by transamination and oxidative decarboxylation, results exclusively ...
... primer, as suggested by the previous observation of d8-Val incorporation into d7-i10:0 (Walters and Steffens, 1990). In accordance with this, the FAS-like extension of d9-i5:0 (d93-methylbutyric acid), which is derived from d10-Leu by transamination and oxidative decarboxylation, results exclusively ...
pdf
... This is explained by crossing over between the gene pairs during meiosis in the parents. Let’s think about the general recombination shown in Fig. 8.1 in this context. The two chromosomes outlined in the figure are in a heterozygous parent, with the wild type alleles for genes A and B (A+ and B+) ar ...
... This is explained by crossing over between the gene pairs during meiosis in the parents. Let’s think about the general recombination shown in Fig. 8.1 in this context. The two chromosomes outlined in the figure are in a heterozygous parent, with the wild type alleles for genes A and B (A+ and B+) ar ...
genetic code: a new understanding of codon
... amino acids. In the third case of reading (Damjanović and Rakočević, 2005) we have the appearance of a specific “mobile loop”. Regarding Figure 2 we see that tryptophan comes one step back “in order” to be together with tyrosine (cf. legend of Table 3) and, at the same time, methionine comes at the ...
... amino acids. In the third case of reading (Damjanović and Rakočević, 2005) we have the appearance of a specific “mobile loop”. Regarding Figure 2 we see that tryptophan comes one step back “in order” to be together with tyrosine (cf. legend of Table 3) and, at the same time, methionine comes at the ...
Signs of change: hormone receptors that regulate plant development
... Plant hormones (phytohormones) are small organic molecules that affect diverse developmental processes. Alterations in hormone responses have been responsible for several important agricultural advances, such as the breeding of semi-dwarf varieties and increased grain production (Ashikari et al., 20 ...
... Plant hormones (phytohormones) are small organic molecules that affect diverse developmental processes. Alterations in hormone responses have been responsible for several important agricultural advances, such as the breeding of semi-dwarf varieties and increased grain production (Ashikari et al., 20 ...
Obligate phototrophy in cyanobacteria: more than a lack of sugar
... substrate for heterotrophic growth [18]. No hybridization signal was revealed with DNA from any of the obligate phototrophic strains. The presence of a poorly or non-homologous gene is unprobable since these strains do not show any uptake of glucose ([6]; data not shown). In the case of the Synechoc ...
... substrate for heterotrophic growth [18]. No hybridization signal was revealed with DNA from any of the obligate phototrophic strains. The presence of a poorly or non-homologous gene is unprobable since these strains do not show any uptake of glucose ([6]; data not shown). In the case of the Synechoc ...
Discovery and classification of ecological diversity in the
... population confers a competitive advantage upon a mutant cell and its clonal (or nearly clonal) descendants; this advantage allows the mutants to replace all competing cells of the same population. However, because different populations use at least somewhat different resources, an adaptive mutant f ...
... population confers a competitive advantage upon a mutant cell and its clonal (or nearly clonal) descendants; this advantage allows the mutants to replace all competing cells of the same population. However, because different populations use at least somewhat different resources, an adaptive mutant f ...
Recombination in HIV and the evolution of drug resistance: for better
... recombination results in the production of progeny virus by random reshuffling of the two parental genomes. However, in contrast to sexual reproduction in higher organisms, there are no distinct sexes in retroviruses. More importantly, in retroviruses recombination of parental genes is frequency dep ...
... recombination results in the production of progeny virus by random reshuffling of the two parental genomes. However, in contrast to sexual reproduction in higher organisms, there are no distinct sexes in retroviruses. More importantly, in retroviruses recombination of parental genes is frequency dep ...
How to ID an Unknown Organism
... • This medium has an oxygen gradient, which means that most of the oxygen is at the top of the tube, and the least amount of oxygen is at the bottom of the tube. To prepare this medium, a reducing agent called Sodium thioglycolate was added, which removes the free oxygen by chemically binding with i ...
... • This medium has an oxygen gradient, which means that most of the oxygen is at the top of the tube, and the least amount of oxygen is at the bottom of the tube. To prepare this medium, a reducing agent called Sodium thioglycolate was added, which removes the free oxygen by chemically binding with i ...
Sialic Acid Production by Metabolically Engineered Escherichia coli
... Medical Importance • Influenza Inhibitors • Marker for Disorders • Biologics • Diagnostics ...
... Medical Importance • Influenza Inhibitors • Marker for Disorders • Biologics • Diagnostics ...
HIGHLY VISCOUS DOUGH FORMING PROPERTIES OF MARAMA PROTEIN
... crosslinking (Tsiami, Bot, Agterof, & Groot, 1997; Mezger, 2006) and therefore a strong protein network. Marama protein, thus, appeared to have some structural stability, but only when small deformations were applied. The complex viscosity (ŋ*) decreased at increasing frequency for marama protein, w ...
... crosslinking (Tsiami, Bot, Agterof, & Groot, 1997; Mezger, 2006) and therefore a strong protein network. Marama protein, thus, appeared to have some structural stability, but only when small deformations were applied. The complex viscosity (ŋ*) decreased at increasing frequency for marama protein, w ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.