... The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal in open access, devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. It presents structured review articles (“cards”) on genes, leukaemias, solid tumours, canc ...
Plant cuticles shine: advances in wax biosynthesis
... the abcg11 single mutant lines [34], indicating that the phenotypes were not additive, suggesting that these gene products may act in the same process or pathway. On the basis of this genetic evidence, and by analogy with the Drosophila eye pigment ABC transporters, a working model has been propose ...
... the abcg11 single mutant lines [34], indicating that the phenotypes were not additive, suggesting that these gene products may act in the same process or pathway. On the basis of this genetic evidence, and by analogy with the Drosophila eye pigment ABC transporters, a working model has been propose ...
A New Type of a Multifunctional ß
... (Thieringer and Kunau, 1991). All d-enoyl-CoA hydratase and all d-3-hydroxyacyl-CoA dehydrogenase domains from the different organisms exhibit pronounced amino acid sequence similarities among themselves (Qin et al., 1997). The same is true for monospecific enzymes or domains displaying 2-enoyl-CoA ...
... (Thieringer and Kunau, 1991). All d-enoyl-CoA hydratase and all d-3-hydroxyacyl-CoA dehydrogenase domains from the different organisms exhibit pronounced amino acid sequence similarities among themselves (Qin et al., 1997). The same is true for monospecific enzymes or domains displaying 2-enoyl-CoA ...
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation
... reduces the accumulation of lipids in nonadipose tissues. Recently, leptin was found to repress RNA levels and enzymatic activity of SCD1 in liver (6). Ob兾ob mice with SCD1 mutations were significantly less obese than ob兾ob controls and had markedly increased energy expenditure with reduced triglyce ...
... reduces the accumulation of lipids in nonadipose tissues. Recently, leptin was found to repress RNA levels and enzymatic activity of SCD1 in liver (6). Ob兾ob mice with SCD1 mutations were significantly less obese than ob兾ob controls and had markedly increased energy expenditure with reduced triglyce ...
BMC Struct Biol. BMC Struct Biol. 2003
... 1E7G Ser5–Gly196,Arg197–Glu383,Pro384–Gly584 1O9X; 1N5U; 4MBN; 1E7G ...
... 1E7G Ser5–Gly196,Arg197–Glu383,Pro384–Gly584 1O9X; 1N5U; 4MBN; 1E7G ...
A New Type of a Multifunctional ß-Oxidation
... (Thieringer and Kunau, 1991). All d-enoyl-CoA hydratase and all d-3-hydroxyacyl-CoA dehydrogenase domains from the different organisms exhibit pronounced amino acid sequence similarities among themselves (Qin et al., 1997). The same is true for monospecific enzymes or domains displaying 2-enoyl-CoA ...
... (Thieringer and Kunau, 1991). All d-enoyl-CoA hydratase and all d-3-hydroxyacyl-CoA dehydrogenase domains from the different organisms exhibit pronounced amino acid sequence similarities among themselves (Qin et al., 1997). The same is true for monospecific enzymes or domains displaying 2-enoyl-CoA ...
genetics - Your Heading Goes Here
... 1. Describe the basic structure of all cells and distinguish between prokaryotic and eukaryotic cells B. Heritable information (7-8, 86-89) 1. Explain the basic structure of DNA and how it encodes information to build proteins. Use a specific example. 2. If a DNA strand has the sequence A-G-T-C-C-T, ...
... 1. Describe the basic structure of all cells and distinguish between prokaryotic and eukaryotic cells B. Heritable information (7-8, 86-89) 1. Explain the basic structure of DNA and how it encodes information to build proteins. Use a specific example. 2. If a DNA strand has the sequence A-G-T-C-C-T, ...
Directionality in FLP Protein-promoted Site
... can be predicted by assuming that sites must be aligned in determined to give an optimal reaction. Reactions were incubated at the same orientation during recombination. In at least two 30 “C for the times indicated and stopped by the addition of 2 pl of 10% sodium dodecyl sulfate and 6 pl of runnin ...
... can be predicted by assuming that sites must be aligned in determined to give an optimal reaction. Reactions were incubated at the same orientation during recombination. In at least two 30 “C for the times indicated and stopped by the addition of 2 pl of 10% sodium dodecyl sulfate and 6 pl of runnin ...
What is Cytogenetics?
... • Loss of a segment of chromosome • Invariably, but not always, results in the loss of important genetic material • In this example the area in the blue brackets is not present (deleted) in its pair designated by the red arrow= 46,XXdel(1)(q24q31) • Female with a deletion of chromosome 1 on the long ...
... • Loss of a segment of chromosome • Invariably, but not always, results in the loss of important genetic material • In this example the area in the blue brackets is not present (deleted) in its pair designated by the red arrow= 46,XXdel(1)(q24q31) • Female with a deletion of chromosome 1 on the long ...
p53 in Hematologic Malignancies
... represent about 10% of the total p53 alterations. False-positives also can occur. For example, in one series of lymphomas, we found 50% of tumors with immunohistochemically detectable p53, but no mutations were detected in the p53 gene.7' This finding could be explained in part because we did not an ...
... represent about 10% of the total p53 alterations. False-positives also can occur. For example, in one series of lymphomas, we found 50% of tumors with immunohistochemically detectable p53, but no mutations were detected in the p53 gene.7' This finding could be explained in part because we did not an ...
Gustatory Responses of Eel Palatine Receptors to Amino Acids and
... ABSTRACT The gustatory receptors of the eel palate were found to be extremely sensitive to amino acids and carboxylic acids. The results obtained are as follows: (a) 11 amino acids which are among naturally occurring amino acids elicited responses in the palatine nerve, but 9 amino acids did not eli ...
... ABSTRACT The gustatory receptors of the eel palate were found to be extremely sensitive to amino acids and carboxylic acids. The results obtained are as follows: (a) 11 amino acids which are among naturally occurring amino acids elicited responses in the palatine nerve, but 9 amino acids did not eli ...
a review on biochemical mechanism of fatty acids synthesis and oil
... using acyltransferase reactions. Recently small abundant proteins called acyl-CoA binding proteins have been identified and it is assumed that these binding proteins are involved in the transportation of acyl-CoA to the endoplasmic reticulum. The mechanism involved in this transportation process is ...
... using acyltransferase reactions. Recently small abundant proteins called acyl-CoA binding proteins have been identified and it is assumed that these binding proteins are involved in the transportation of acyl-CoA to the endoplasmic reticulum. The mechanism involved in this transportation process is ...
Final published version
... Manipulation of NADH-dependent steps, and particularly disruption of the las-located lactate dehydrogenase (ldh) gene in Lactococcus lactis, is common to engineering strategies envisaging the accumulation of reduced end products other than lactate. Reverse transcription-PCR experiments revealed that ...
... Manipulation of NADH-dependent steps, and particularly disruption of the las-located lactate dehydrogenase (ldh) gene in Lactococcus lactis, is common to engineering strategies envisaging the accumulation of reduced end products other than lactate. Reverse transcription-PCR experiments revealed that ...
Statistical analysis of simple repeats in the human genome
... associated with any of the single- or di-nucleotide probabilities, nor with any mnucleotide probability, with m42: This finding is consistent with the general acceptance of the failure of zeroth- and first-order Markovian models of simple repeats to fully account for ‘‘linguistic’’ features of non-cod ...
... associated with any of the single- or di-nucleotide probabilities, nor with any mnucleotide probability, with m42: This finding is consistent with the general acceptance of the failure of zeroth- and first-order Markovian models of simple repeats to fully account for ‘‘linguistic’’ features of non-cod ...
The monocarboxylate transporter family
... Molecular Mechanism of MCT1. The molecular mechanism by which MCT1 transports monocarboxylates has been extensively studied by analysis of transport kinetics, the use of inhibitors and more recently through site-directed mutagenesis. Detailed kinetic analysis of monocarboxylate transport in erythroc ...
... Molecular Mechanism of MCT1. The molecular mechanism by which MCT1 transports monocarboxylates has been extensively studied by analysis of transport kinetics, the use of inhibitors and more recently through site-directed mutagenesis. Detailed kinetic analysis of monocarboxylate transport in erythroc ...
Chapter2 Radiolabeled amino acids: basic aspects and
... mRNA) starts at the cytoplasmatic ribosomes. Cells regulate which specific proteins are synthesized and also the total amount of protein synthesis (4). The process of protein synthesis is a coordinated interplay of more than hundred macromolecules and subject to very complex regulation, involving fa ...
... mRNA) starts at the cytoplasmatic ribosomes. Cells regulate which specific proteins are synthesized and also the total amount of protein synthesis (4). The process of protein synthesis is a coordinated interplay of more than hundred macromolecules and subject to very complex regulation, involving fa ...
In the beginning: the initiation of meiosis
... takes place after the animal reaches puberty. In contrast, in the testis, spermatocytes initiate meiosis throughout the life of the animal in synchronous waves starting at about a week after birth. Consequently, the signal for initiating meiosis must be regulated differently in males and females. Re ...
... takes place after the animal reaches puberty. In contrast, in the testis, spermatocytes initiate meiosis throughout the life of the animal in synchronous waves starting at about a week after birth. Consequently, the signal for initiating meiosis must be regulated differently in males and females. Re ...
lntraclonal mating in Trypanosoma brucei is
... 1995). Other lower eukaryotes have multiple mating types, determined by loci which encode or control production of specific pheromones ; such systems ensure that mating occurs only between organisms of different ...
... 1995). Other lower eukaryotes have multiple mating types, determined by loci which encode or control production of specific pheromones ; such systems ensure that mating occurs only between organisms of different ...
CS 5263 Bioinformatics
... • Assume each position of the alignment is independently sampled from some distribution of amino acids • ps: probability of amino acid s in the sequences • Probability of seeing an amino acid s aligned to an amino acid t by chance is – Pr(s, t | U) = ps * pt ...
... • Assume each position of the alignment is independently sampled from some distribution of amino acids • ps: probability of amino acid s in the sequences • Probability of seeing an amino acid s aligned to an amino acid t by chance is – Pr(s, t | U) = ps * pt ...
Cloning and Expression of Bovine Sodium/Glucose Cotransporters* J. Dairy Sci. 88:182–194
... of the SGLT family (Mackenzie et al., 1994). However, its function may need to be reevaluated because human SGLT3 apparently does not transport glucose (Wright and Turk, 2004). Little is known about the isoforms SGLT4 to 6, except that SGLT4 and 6 are expressed in a wide variety of tissues, whereas ...
... of the SGLT family (Mackenzie et al., 1994). However, its function may need to be reevaluated because human SGLT3 apparently does not transport glucose (Wright and Turk, 2004). Little is known about the isoforms SGLT4 to 6, except that SGLT4 and 6 are expressed in a wide variety of tissues, whereas ...
PDF - Journal of Genomics
... Rag4, and Rag5) have been reported (19-26). However, biotypes of the soybean aphid have been identified in Midwest growing regions; biotypes are based on the ability to overcome host-plant resistance provided by one or more of these Rag genes. Biotype 2 can override the Rag1 gene (27), while biotype ...
... Rag4, and Rag5) have been reported (19-26). However, biotypes of the soybean aphid have been identified in Midwest growing regions; biotypes are based on the ability to overcome host-plant resistance provided by one or more of these Rag genes. Biotype 2 can override the Rag1 gene (27), while biotype ...
Protein proteinase inhibitors from avian egg whites
... the enzyme in the enzyme-inhibitor complex. This hypervariability of reactive-site residues in members of the serpin family is a frequently encountered phenomenon rather than a rarity [33 – 35]. The hypervariability is not limited to the third domain but may occur in the first and second domains. Ar ...
... the enzyme in the enzyme-inhibitor complex. This hypervariability of reactive-site residues in members of the serpin family is a frequently encountered phenomenon rather than a rarity [33 – 35]. The hypervariability is not limited to the third domain but may occur in the first and second domains. Ar ...
Hierarchical Text Categorization and Its Evaluation
... • to try global hierarchical approach with other learning algorithms • to extend the gene annotation training sets with similar documents from Medline • to perform similar task for other organisms • to use gene annotations in gene classification and clustering ...
... • to try global hierarchical approach with other learning algorithms • to extend the gene annotation training sets with similar documents from Medline • to perform similar task for other organisms • to use gene annotations in gene classification and clustering ...
Richard Goldschmidt: hopeful monsters and other `heresies`
... was appointed to the Kaiser Wilhelm Institute for Biology in Berlin (FIG. 1). As Director of his own section of the Institute, Goldschmidt was free from teaching duties and could devote his full energy to research. Because the production of intersexes depended on the mating of different geographical ...
... was appointed to the Kaiser Wilhelm Institute for Biology in Berlin (FIG. 1). As Director of his own section of the Institute, Goldschmidt was free from teaching duties and could devote his full energy to research. Because the production of intersexes depended on the mating of different geographical ...
Morgan and Linkage
... The probability that a recombination event occurs between two loci is a function of the distance between the two loci. The alleles at two loci that are far apart on a chromosome are more likely to encounter a recombination event recombine than the alleles for two loci that are close together on that ...
... The probability that a recombination event occurs between two loci is a function of the distance between the two loci. The alleles at two loci that are far apart on a chromosome are more likely to encounter a recombination event recombine than the alleles for two loci that are close together on that ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.