Frequent, independent transfers of a catabolic gene from bacteria to
... supplementary material, figure S3). Supported nodes are indicated with grey circles (bootstrap . 70). mining transcript databases allowed the identification of all or part of acdS mRNA in almost all stramenopiles and fungi studied (see the electronic supplementary material, figure S7). This indicate ...
... supplementary material, figure S3). Supported nodes are indicated with grey circles (bootstrap . 70). mining transcript databases allowed the identification of all or part of acdS mRNA in almost all stramenopiles and fungi studied (see the electronic supplementary material, figure S7). This indicate ...
Two novel genetic lesions and a common BH4-responsive
... Genetic analysis in 23 Italian patients with PAH deficiency led to the identification of two novel transversions ðc:842C > G; c:859C > GÞ and 20 previously described mutations in the PAH gene. The new nucleotide substitution c:842C > G, in exon 7, leads to the novel P281R amino acid change (Fig. 1A). ...
... Genetic analysis in 23 Italian patients with PAH deficiency led to the identification of two novel transversions ðc:842C > G; c:859C > GÞ and 20 previously described mutations in the PAH gene. The new nucleotide substitution c:842C > G, in exon 7, leads to the novel P281R amino acid change (Fig. 1A). ...
PSEUDOCHOLINESTERASE ACTIVITY: DETERMINATION AND INTERPRETATION IN PEDIATRIC ANESTHESIA A
... In fact, there is no study establishing the norms from age 6 months to 3 years. In fact, several limitations to genotyping by biochemical methods exist: First, biochemical testing cannot distinguish between primary and secondary pseudocholinesterase deficiency, the latter caused by drugs, hepatic di ...
... In fact, there is no study establishing the norms from age 6 months to 3 years. In fact, several limitations to genotyping by biochemical methods exist: First, biochemical testing cannot distinguish between primary and secondary pseudocholinesterase deficiency, the latter caused by drugs, hepatic di ...
The final publication is available at Copyright - RiuNet
... effects, as in other plants, are in part due to the presence of flavonoids and phenolic compounds [5, 6]. ...
... effects, as in other plants, are in part due to the presence of flavonoids and phenolic compounds [5, 6]. ...
Document
... Co-infection weakens selection against epistatic mutations in RNA viruses. Genetics. 2004 Sep;168(1):9-19. ...
... Co-infection weakens selection against epistatic mutations in RNA viruses. Genetics. 2004 Sep;168(1):9-19. ...
Gene Section ALK (anaplastic lymphoma kinase) Atlas of Genetics and Cytogenetics
... Althouth presenting as a high grade tumour, a 80% five year survival is associated with this anomaly. Cytogenetics Additional anomalies and complex karyotypes are most often found. Hybrid/Mutated gene 5' NPM1 - 3' ALK on the der(5). Abnormal protein 680 amino acids, 80 kDa; N-term 116 amino acids fr ...
... Althouth presenting as a high grade tumour, a 80% five year survival is associated with this anomaly. Cytogenetics Additional anomalies and complex karyotypes are most often found. Hybrid/Mutated gene 5' NPM1 - 3' ALK on the der(5). Abnormal protein 680 amino acids, 80 kDa; N-term 116 amino acids fr ...
Molecular and Biochemical Studies of Acute Intermittent Porphyria in
... Of the 489 family members, AIP was diagnosed in 196 patients (84 males, 112 females; age range, 15–78 years; 75 symptomatic and 121 symptom free) and excluded in 293 healthy relatives (146 males, 147 females; age range, 15– 61 years). We examined 239 individuals with mutation analysis and 381 indivi ...
... Of the 489 family members, AIP was diagnosed in 196 patients (84 males, 112 females; age range, 15–78 years; 75 symptomatic and 121 symptom free) and excluded in 293 healthy relatives (146 males, 147 females; age range, 15– 61 years). We examined 239 individuals with mutation analysis and 381 indivi ...
The Urea Cycle - Rose
... Although glutamine is a useful, non-toxic ammonium carrier molecule, release of glutamine depletes the tissue of glutamate. This is particularly important in the brain, because glutamate is a neurotransmitter, and is the precursor of g-aminobutyric acid (GABA), another neurotransmitter. In addition ...
... Although glutamine is a useful, non-toxic ammonium carrier molecule, release of glutamine depletes the tissue of glutamate. This is particularly important in the brain, because glutamate is a neurotransmitter, and is the precursor of g-aminobutyric acid (GABA), another neurotransmitter. In addition ...
DnaJ-related protein essential for placentation - Development
... cell adhesion molecules. Vascular cell adhesion molecule-1 (VCAM1) is expressed on the distal tip of the allantois in ...
... cell adhesion molecules. Vascular cell adhesion molecule-1 (VCAM1) is expressed on the distal tip of the allantois in ...
Biomart/ GENOME ALIGNMENT III
... and the mouse sequence. Even in remote organisms such as fugu and zebrafish some of the human exons are conserved. Between rat and mouse and human in the region 1000 bp upstream of the first exons parts of the sequence are conserved as well. These might correspond to the regulatory motifs, responsib ...
... and the mouse sequence. Even in remote organisms such as fugu and zebrafish some of the human exons are conserved. Between rat and mouse and human in the region 1000 bp upstream of the first exons parts of the sequence are conserved as well. These might correspond to the regulatory motifs, responsib ...
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
... (from E. coli to D. radiodurans and Corynebacterium) of the genes encoding these precisely truncated GluRS fragments suggests that these proteins may have a yet unknown function. Nonetheless, GluX was not analyzed further. Class I lysyl-tRNA synthetase (LysRS) is structurally very related (27) and d ...
... (from E. coli to D. radiodurans and Corynebacterium) of the genes encoding these precisely truncated GluRS fragments suggests that these proteins may have a yet unknown function. Nonetheless, GluX was not analyzed further. Class I lysyl-tRNA synthetase (LysRS) is structurally very related (27) and d ...
The Genetic Code Is One in a Million
... in the distribution of codon assignments. It has, for example, been shown that the code minimizes the effects of point mutation or mistranslation: erroneous codons are either synonymous or code for an amino acid with chemical properties very similar to those of the one that would have been present h ...
... in the distribution of codon assignments. It has, for example, been shown that the code minimizes the effects of point mutation or mistranslation: erroneous codons are either synonymous or code for an amino acid with chemical properties very similar to those of the one that would have been present h ...
Review A model for chromosome structure during the mitotic
... Figures 1^11 (overleaf). Diagrammatic representations of chromosome structure through the mitotic cell cycle. Drawings are not to scale. Telophase/G1 . (A) Longitudinal view of a segment of a decondensing chromosome during telophase or a decondensed chromosome during G1. The anaphase chromosome core ...
... Figures 1^11 (overleaf). Diagrammatic representations of chromosome structure through the mitotic cell cycle. Drawings are not to scale. Telophase/G1 . (A) Longitudinal view of a segment of a decondensing chromosome during telophase or a decondensed chromosome during G1. The anaphase chromosome core ...
Resistance to cephalosporins and carbapenems in Gram
... Enterobacteriaceae are ESBL enzymes of Ambler class A. Of special relevance are variants of broad-spectrum -lactamases TEM-1, TEM-2, and SHV-1 that are generated by mutations which extend their substrate specificity to 3rd and 4th generation cephalosporins, in particular to cefotaxime, ceftriaxone, ...
... Enterobacteriaceae are ESBL enzymes of Ambler class A. Of special relevance are variants of broad-spectrum -lactamases TEM-1, TEM-2, and SHV-1 that are generated by mutations which extend their substrate specificity to 3rd and 4th generation cephalosporins, in particular to cefotaxime, ceftriaxone, ...
A mutation in the Arabidopsis mTERFrelated plastid protein
... three other mTERF proteins is shown in Figure S1 in Supporting Information. Arabidopsis contains at least 35 different mTERF proteins (http://smart.embl-heidelberg.de/). One of them, PTAC15, has been shown previously to be associated with transcriptionally active DNA and to be localized in plastids ...
... three other mTERF proteins is shown in Figure S1 in Supporting Information. Arabidopsis contains at least 35 different mTERF proteins (http://smart.embl-heidelberg.de/). One of them, PTAC15, has been shown previously to be associated with transcriptionally active DNA and to be localized in plastids ...
Introduction: - Statistical Science
... Inputs to GSEA. Expression dataset D with levels of N genes for k samples. A sorted gene list L and an associated vector R of gene-phenotype correlations; alternatively a ranking procedure to produce L (including a ranking metric M, e.g., t-test or signal to noise ratio, and 1) phenotype class v ...
... Inputs to GSEA. Expression dataset D with levels of N genes for k samples. A sorted gene list L and an associated vector R of gene-phenotype correlations; alternatively a ranking procedure to produce L (including a ranking metric M, e.g., t-test or signal to noise ratio, and 1) phenotype class v ...
Fermentation for Liquid-type Yogurt with Lactobacillus casei 911LC
... 2 ml/min and two mobile phases were used: solvent A was 0.05 M sodium acetate (pH 6.3), and solvent B, methanol: Changes in pH and titratable acidity THF (90:10, v/v). The linear gradient of solvent B was Changes in pH during the 72 h fermentation of yogurt programmed at 5 levels as follows: initial ...
... 2 ml/min and two mobile phases were used: solvent A was 0.05 M sodium acetate (pH 6.3), and solvent B, methanol: Changes in pH and titratable acidity THF (90:10, v/v). The linear gradient of solvent B was Changes in pH during the 72 h fermentation of yogurt programmed at 5 levels as follows: initial ...
Deoxyribonucleic Acid Base Compositions and Nucleotide
... tide distribution, (TI + guanine-plus-cytosine (G+C) frequency curves (6), describe an additional physicochemical quality of the bacterial genome. The DNA nucleotide distributions of some 2,500 bacterial strains were found to be “quite similar within each genus,” but varied considerably between gene ...
... tide distribution, (TI + guanine-plus-cytosine (G+C) frequency curves (6), describe an additional physicochemical quality of the bacterial genome. The DNA nucleotide distributions of some 2,500 bacterial strains were found to be “quite similar within each genus,” but varied considerably between gene ...
122602 Hydrophobic Surfactant Proteins in Lung Function
... failure in the first 24 to 48 hours of life. Pulmonaryfunction studies and radiographic findings in these infants are consistent with surfactant deficiency. The disorder is usually inherited as an autosomal recessive condition; a single mutation, termed 121ins 2 (a net insertion of two nucleotides i ...
... failure in the first 24 to 48 hours of life. Pulmonaryfunction studies and radiographic findings in these infants are consistent with surfactant deficiency. The disorder is usually inherited as an autosomal recessive condition; a single mutation, termed 121ins 2 (a net insertion of two nucleotides i ...
Chapter 1 - Institut Montefiore
... Reading the code • Because there are only 20 amino acids that need to be coded, the genetic code can be said to be degenerate, with the third position often being redundant • Depending on the starting point of reading, there are three possible variants to translate a given base sequence into an amin ...
... Reading the code • Because there are only 20 amino acids that need to be coded, the genetic code can be said to be degenerate, with the third position often being redundant • Depending on the starting point of reading, there are three possible variants to translate a given base sequence into an amin ...
Meiosis Notes
... Fertilization—the fusion of male and female gametes—generates new combinations of alleles in a zygote. The zygote undergoes cell division by mitosis and eventually forms a new organism. ...
... Fertilization—the fusion of male and female gametes—generates new combinations of alleles in a zygote. The zygote undergoes cell division by mitosis and eventually forms a new organism. ...
NEW YORK STATE MEDICAID PROGRAM LABORATORY
... concentration is clinically relevant as a part of a regimen designed to attain and sustain therapeutic effect by maintenance of blood level within a defined range. The intensity and probability of therapeutic or toxic effect must quantitatively correlate with blood concentration. In addition, one or ...
... concentration is clinically relevant as a part of a regimen designed to attain and sustain therapeutic effect by maintenance of blood level within a defined range. The intensity and probability of therapeutic or toxic effect must quantitatively correlate with blood concentration. In addition, one or ...
Document
... The yellow perch is one of a group of important fishes which exhibit a sexual size dimorphism (SSD) in which females grow faster than males. Studies have identified 17β-estradiol (E2) as a growth stimulator in yellow perch SSD (Malison et al., 1988; Malison et al., 1986; Malison et al., 1985) and Ro ...
... The yellow perch is one of a group of important fishes which exhibit a sexual size dimorphism (SSD) in which females grow faster than males. Studies have identified 17β-estradiol (E2) as a growth stimulator in yellow perch SSD (Malison et al., 1988; Malison et al., 1986; Malison et al., 1985) and Ro ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.