Introduction: - Statistical Science
... Inputs to GSEA. Expression dataset D with levels of N genes for k samples. A sorted gene list L and an associated vector R of gene-phenotype correlations; alternatively a ranking procedure to produce L (including a ranking metric M, e.g., t-test or signal to noise ratio, and 1) phenotype class v ...
... Inputs to GSEA. Expression dataset D with levels of N genes for k samples. A sorted gene list L and an associated vector R of gene-phenotype correlations; alternatively a ranking procedure to produce L (including a ranking metric M, e.g., t-test or signal to noise ratio, and 1) phenotype class v ...
meiosis I - HCC Learning Web
... Offspring acquire genes from parents by inheriting chromosomes • In a literal sense, children do not inherit particular physical traits from their parents. It is genes that are actually inherited • Genes are the units of heredity, and are made up of segments of DNA • Genes are passed to the next ge ...
... Offspring acquire genes from parents by inheriting chromosomes • In a literal sense, children do not inherit particular physical traits from their parents. It is genes that are actually inherited • Genes are the units of heredity, and are made up of segments of DNA • Genes are passed to the next ge ...
Chapter 1 - Institut Montefiore
... Reading the code • Because there are only 20 amino acids that need to be coded, the genetic code can be said to be degenerate, with the third position often being redundant • Depending on the starting point of reading, there are three possible variants to translate a given base sequence into an amin ...
... Reading the code • Because there are only 20 amino acids that need to be coded, the genetic code can be said to be degenerate, with the third position often being redundant • Depending on the starting point of reading, there are three possible variants to translate a given base sequence into an amin ...
122602 Hydrophobic Surfactant Proteins in Lung Function
... failure in the first 24 to 48 hours of life. Pulmonaryfunction studies and radiographic findings in these infants are consistent with surfactant deficiency. The disorder is usually inherited as an autosomal recessive condition; a single mutation, termed 121ins 2 (a net insertion of two nucleotides i ...
... failure in the first 24 to 48 hours of life. Pulmonaryfunction studies and radiographic findings in these infants are consistent with surfactant deficiency. The disorder is usually inherited as an autosomal recessive condition; a single mutation, termed 121ins 2 (a net insertion of two nucleotides i ...
Virology Journal
... out of 52 (69%) of the ORFs for phages eiAU, eiDWF, and eiMSLS, respectively, share significant sequence similarity to known protein sequences contained in the GenBank nr/nt database (Table 1). Of the ORFs with significant sequence similarity to sequences in GenBank, putative functions could only be ...
... out of 52 (69%) of the ORFs for phages eiAU, eiDWF, and eiMSLS, respectively, share significant sequence similarity to known protein sequences contained in the GenBank nr/nt database (Table 1). Of the ORFs with significant sequence similarity to sequences in GenBank, putative functions could only be ...
Passenger Protein Determines Translocation Versus Retention in
... sequence and signal anchors (SAs) facilitate translocation and topology of proteins. To understand the function of type-I SAs (SA-Is), we evaluated translocation of aromatase, whose signal anchor follows a hydrophilic region. Aromatase SA-I mediates translocation of a short N-terminal hydrophillic d ...
... sequence and signal anchors (SAs) facilitate translocation and topology of proteins. To understand the function of type-I SAs (SA-Is), we evaluated translocation of aromatase, whose signal anchor follows a hydrophilic region. Aromatase SA-I mediates translocation of a short N-terminal hydrophillic d ...
Association of estrogen receptor β gene polymorphisms with bulimic
... So far, only a few variants of the ERb gene have been reported and characterized with regard to allele frequency.16–19 Rosenkranz et al16 performed a systematic mutation screening of ERb in probands of different weight extremes and identified five different genetic variants. Only two of these appear ...
... So far, only a few variants of the ERb gene have been reported and characterized with regard to allele frequency.16–19 Rosenkranz et al16 performed a systematic mutation screening of ERb in probands of different weight extremes and identified five different genetic variants. Only two of these appear ...
New liquid absorbents for the removal of CO2 from gas
... Membrane contactors present also an alternative to this problem and can serve to remove carbon dioxide from such anaesthetics closed systems, where energy-efficiency, bio-compatibility and environmental safety are essential. The absorbents have to be highly selective, posses a high absorption capaci ...
... Membrane contactors present also an alternative to this problem and can serve to remove carbon dioxide from such anaesthetics closed systems, where energy-efficiency, bio-compatibility and environmental safety are essential. The absorbents have to be highly selective, posses a high absorption capaci ...
Study of the distribution of autotrophic CO2 fixation
... ‘marine group’-1 Crenarchaeota, which are abundant in the sea (Karner et al., 2001), were initially described as representatives of the Crenarchaeota, and the taxonomic entities ‘Cenarchaeales’ (Preston et al., 1996) or ‘Nitrosopumilales’ (Könneke et al., 2005) have been proposed. However, the phyl ...
... ‘marine group’-1 Crenarchaeota, which are abundant in the sea (Karner et al., 2001), were initially described as representatives of the Crenarchaeota, and the taxonomic entities ‘Cenarchaeales’ (Preston et al., 1996) or ‘Nitrosopumilales’ (Könneke et al., 2005) have been proposed. However, the phyl ...
HOM-C/Hox genes and four interacting loci
... involved in the development of the adult ray pattern, and demonstrated a role of six genes essential to the process (Baird et al., 1991). From these studies we concluded that the rays were not morphogenetically equivalent. In spite of the fact that they arose from repetition of a stereotyped cell su ...
... involved in the development of the adult ray pattern, and demonstrated a role of six genes essential to the process (Baird et al., 1991). From these studies we concluded that the rays were not morphogenetically equivalent. In spite of the fact that they arose from repetition of a stereotyped cell su ...
A comparison of the structure of echinomycin and triostin A
... manner in which the quinoxaline antibiotics are inserted into the DNA duplex. The numbering system of the nucleotides in the duplex is shown together with the designation given to the different crosshatched quinoxaline rings. There is a two-fold axis in the middle of the molecule, so that half of th ...
... manner in which the quinoxaline antibiotics are inserted into the DNA duplex. The numbering system of the nucleotides in the duplex is shown together with the designation given to the different crosshatched quinoxaline rings. There is a two-fold axis in the middle of the molecule, so that half of th ...
Advances in maize genomics: the emergence of positional cloning
... that a 0.1 cM distance is contained on 1–2 BACs. If no BAC or BAC contig is available for a particular marker, or if one wishes to assemble a contig, a BAC library needs to be screened. The most widely used BAC library, ZMMBBb, consists of 247 680 clones, with an average insert size of 137 kb, that ...
... that a 0.1 cM distance is contained on 1–2 BACs. If no BAC or BAC contig is available for a particular marker, or if one wishes to assemble a contig, a BAC library needs to be screened. The most widely used BAC library, ZMMBBb, consists of 247 680 clones, with an average insert size of 137 kb, that ...
2016 HSC Biology Marking Guidelines
... • Provides relevant information about the use of microorganism identification and/or culture in establishing the cause of a disease • Provides some relevant information ...
... • Provides relevant information about the use of microorganism identification and/or culture in establishing the cause of a disease • Provides some relevant information ...
Novel Ciliate Genetic Code Variants Including the Reassignment of
... recoding mechanisms in translation of their transcriptomes. Most organisms have either 1 or 2 stop codons reassigned to amino acids. It is also clear that evolution of TAA and TAG codon meanings is coupled, i.e., if one of these codons is reassigned the other codon is also reassigned. This is most l ...
... recoding mechanisms in translation of their transcriptomes. Most organisms have either 1 or 2 stop codons reassigned to amino acids. It is also clear that evolution of TAA and TAG codon meanings is coupled, i.e., if one of these codons is reassigned the other codon is also reassigned. This is most l ...
Networks in leaf development
... rs2 mutants, proximal features of the sheath, ligule and auricle (Figure 2) are displaced distally into the leaf blade [47]. rs2, therefore, is defective in proximodistal patterning. On the basis of the maize phenotype, an alternative interpretation of the phan phenotype proposed that radialisation ...
... rs2 mutants, proximal features of the sheath, ligule and auricle (Figure 2) are displaced distally into the leaf blade [47]. rs2, therefore, is defective in proximodistal patterning. On the basis of the maize phenotype, an alternative interpretation of the phan phenotype proposed that radialisation ...
lecture - Berkeley MCB
... Note: this diagram is not entirely correct (in an entirelly incorrect sort of way), because the estrogen receptor (ER), a class I nuclear hormone receptor, is not typically bound to target genes in the absence of hormone – such behavior is characteristic of class II nuclear hormone receptors, such ...
... Note: this diagram is not entirely correct (in an entirelly incorrect sort of way), because the estrogen receptor (ER), a class I nuclear hormone receptor, is not typically bound to target genes in the absence of hormone – such behavior is characteristic of class II nuclear hormone receptors, such ...
Mutation specific therapies
... (restores the genetic code for certain deletions). Here I will explain why these approaches can not be applied to all patients. A you can read in the mutations section, a disruption of the genetic code leads to the use of aberrant protein subunits, whereas a point mutations cause a premature stop si ...
... (restores the genetic code for certain deletions). Here I will explain why these approaches can not be applied to all patients. A you can read in the mutations section, a disruption of the genetic code leads to the use of aberrant protein subunits, whereas a point mutations cause a premature stop si ...
Cytogenetics
... Results from errors in division during meiosis, where a daughter cell receives both pairs of a particular chromosome (nondisjunction errors). Addition of an extra chromosome, trisomy, has been described for all the chromosomes but only three autosomal trisomies survive to birth. Those are trisomies ...
... Results from errors in division during meiosis, where a daughter cell receives both pairs of a particular chromosome (nondisjunction errors). Addition of an extra chromosome, trisomy, has been described for all the chromosomes but only three autosomal trisomies survive to birth. Those are trisomies ...
3. BIOMOLECULES I. CARBOHYDRATES
... 1. 11.1. Biosynthesis of lipids ................................................................................................. 1.1. 11. 1. 1. Biosynthesis of triglicerides ...................................................................... 1.1.1. 11.1.1.1. Biosynthesis of fatty acids ......... ...
... 1. 11.1. Biosynthesis of lipids ................................................................................................. 1.1. 11. 1. 1. Biosynthesis of triglicerides ...................................................................... 1.1.1. 11.1.1.1. Biosynthesis of fatty acids ......... ...
SPA1: A New Genetic Locus Involved in Phytochrome A
... these genes encode negative regulators of light signaling that normally are active in the dark and inactivated by light (McNellis et al., 1994; Misera et al., 1994). However, recently, dominant mutants at two apparently novel loci have been described as well (Kim et al., 1996). Because mutations at ...
... these genes encode negative regulators of light signaling that normally are active in the dark and inactivated by light (McNellis et al., 1994; Misera et al., 1994). However, recently, dominant mutants at two apparently novel loci have been described as well (Kim et al., 1996). Because mutations at ...
Classification and domain analysis of protein
... 1296, 5576 and 2028 genes were observed as duplicate entries. Following the removal of the above duplicate entries, there were 17,816, 16,656 and 18,274 protein coding genes in the chimpanzee, gorilla and orangutan genomes respectively. The process of classifying protein kinase genes from the genome ...
... 1296, 5576 and 2028 genes were observed as duplicate entries. Following the removal of the above duplicate entries, there were 17,816, 16,656 and 18,274 protein coding genes in the chimpanzee, gorilla and orangutan genomes respectively. The process of classifying protein kinase genes from the genome ...
Learn more by reading original document
... 3) The DELAY DIVERGENT SEQUENCES switch delays the alignment of the most distantly related sequences until after the most closely related sequences have been aligned. The setting shows the percent identity level required to delay the addition of a sequence; sequences that are less identical than thi ...
... 3) The DELAY DIVERGENT SEQUENCES switch delays the alignment of the most distantly related sequences until after the most closely related sequences have been aligned. The setting shows the percent identity level required to delay the addition of a sequence; sequences that are less identical than thi ...
A New Type of a Multifunctional ß
... (Thieringer and Kunau, 1991). All d-enoyl-CoA hydratase and all d-3-hydroxyacyl-CoA dehydrogenase domains from the different organisms exhibit pronounced amino acid sequence similarities among themselves (Qin et al., 1997). The same is true for monospecific enzymes or domains displaying 2-enoyl-CoA ...
... (Thieringer and Kunau, 1991). All d-enoyl-CoA hydratase and all d-3-hydroxyacyl-CoA dehydrogenase domains from the different organisms exhibit pronounced amino acid sequence similarities among themselves (Qin et al., 1997). The same is true for monospecific enzymes or domains displaying 2-enoyl-CoA ...
... The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal in open access, devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. It presents structured review articles (“cards”) on genes, leukaemias, solid tumours, canc ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.